Cancers, Vol. 12, Pages 2377: COVID-19 and Cancer: Lessons Learnt from a Michigan Hotspot
Cancers, Vol. 12, Pages 2377: COVID-19 and Cancer: Lessons Learnt from a Michigan Hotspot Cancers doi: 10.3390/cancers12092377 Authors: Sunny R. K. Singh Kannan Thanikachalam Hiba Jabbour-Aida Laila M. Poisson Gazala Khan (1) Background: Outcomes with coronavirus disease 2019 (COVID-19) have been worse in those with comorbidities and amongst minorities. In our study, we describe outcomes amongst cancer patients in Detroit, a major COVID-19 hotspot with a predominant inner-city...
Sat Aug 22, 2020 03:00
Cancers, Vol. 12, Pages 2376: Detection of Oral Dysplastic and Early Cancerous Lesions by Polarization-Sensitive Optical Coherence Tomography Cancers doi: 10.3390/cancers12092376 Authors: Ping-Hsien Chen Hung-Yi Lee Yi-Fen Chen Yi-Chen Yeh Kuo-Wei Chang Ming-Chih Hou Wen-Chuan Kuo Detection of oral dysplastic and early-stage cancerous lesions is difficult with the current tools. Half of oral cancers are diagnosed in a late stage. Detection of early stromal change to...
Sat Aug 22, 2020 03:00
Cancers, Vol. 12, Pages 2375: Guidelines for Management of Urgent Symptoms in Patients with Cholangiocarcinoma and Biliary Stents or Catheters using the Modified RAND/UCLA Delphi Process Cancers doi: 10.3390/cancers12092375 Authors: Renuka V. Iyer Susan G. Acquisto John A. Bridgewater Michael A. Choti Theodore S. Hong Bela Kis Peter A. Mead Neehar D. Parikh Lewis R. Roberts Rebecca Roberts Riad Salem Jason K. Sicklick Richard S. Siegel Jonathan R. Whisenant...
Fri Aug 21, 2020 03:00
Cancers, Vol. 12, Pages 2372: Role of the CXCR4-LASP1 Axis in the Stabilization of Snail1 in Triple-Negative Breast Cancer Cancers doi: 10.3390/cancers12092372 Authors: Boopathi Subramaniyan Sangita Sridharan Cory M. Howard Augustus M.C. Tilley Tupa Basuroy Ivana de la Serna Elke Butt Dayanidhi Raman The CXCL12-CXCR4 axis plays a vital role in many steps of breast cancer metastasis, but the molecular mechanisms have not been fully elucidated. We previously reported...
Fri Aug 21, 2020 03:00
Cancers, Vol. 12, Pages 2374: Utility of Comprehensive Serum Glycopeptide Spectra Analysis (CSGSA) for the Detection of Early Stage Epithelial Ovarian Cancer Cancers doi: 10.3390/cancers12092374 Authors: Koji Matsuo Kazuhiro Tanabe Masaru Hayashi Masae Ikeda Miwa Yasaka Hiroko Machida Masako Shida Kenji Sato Hiroshi Yoshida Takeshi Hirasawa Tadashi Imanishi Mikio Mikami Comprehensive serum glycopeptide spectra analysis (CSGSA) evaluates >10,000...
Fri Aug 21, 2020 03:00
Cancers, Vol. 12, Pages 2373: Comprehensive Serum Glycopeptide Spectra Analysis Combined with Artificial Intelligence (CSGSA-AI) to Diagnose Early-Stage Ovarian Cancer Cancers doi: 10.3390/cancers12092373 Authors: Kazuhiro Tanabe Masae Ikeda Masaru Hayashi Koji Matsuo Miwa Yasaka Hiroko Machida Masako Shida Tomoko Katahira Tadashi Imanishi Takeshi Hirasawa Kenji Sato Hiroshi Yoshida Mikio Mikami Ovarian cancer is a leading cause of deaths among gynecological...
Fri Aug 21, 2020 03:00
Cancers, Vol. 12, Pages 2371: Dual Inhibition of Autophagy and PI3K/AKT/MTOR Pathway as a Therapeutic Strategy in Head and Neck Squamous Cell Carcinoma Cancers doi: 10.3390/cancers12092371 Authors: Monique Bernard Guillaume B. Cardin Maxime Cahuzac Tareck Ayad Eric Bissada Louis Guertin Houda Bahig Phuc Felix Nguyen-Tan Edith Filion Olivier Ballivy Denis Soulieres Francis Rodier Apostolos Christopoulos Genomic analyses of head and neck squamous cell...
Fri Aug 21, 2020 03:00
Cancers, Vol. 12, Pages 2370: Novel Caffeic Acid Phenethyl Ester-Mortalin Antibody Nanoparticles Offer Enhanced Selective Cytotoxicity to Cancer Cells Cancers doi: 10.3390/cancers12092370 Authors: Jia Wang Priyanshu Bhargava Yue Yu Anissa Nofita Sari Huayue Zhang Noriyuki Ishii Kangmin Yan Zhenya Zhang Yoshiyuki Ishida Keiji Terao Sunil C. Kaul Eijiro Miyako Renu Wadhwa Caffeic acid phenethyl ester (CAPE) is a key bioactive ingredient of honeybee propolis...
Fri Aug 21, 2020 03:00
Cancers, Vol. 12, Pages 2369: Vascular Shutdown by Photodynamic Therapy Using Talaporfin Sodium Cancers doi: 10.3390/cancers12092369 Authors: Taketo Suzuki Mamoru Tanaka Makiko Sasaki Hiroshi Ichikawa Hirotada Nishie Hiromi Kataoka Photodynamic therapy (PDT) is an attractive cancer treatment modality. Talaporfin sodium, a second-generation photosensitizer, results in lower systemic toxicity and relatively better selective tumor destruction than first-generation photosensitizers....
Fri Aug 21, 2020 03:00
Cancers, Vol. 12, Pages 2368: Identification of Novel Transcriptome Signature as a Potential Prognostic Biomarker for Anti-Angiogenic Therapy in Glioblastoma Multiforme Cancers doi: 10.3390/cancers12092368 Authors: Shuhua Zheng Wensi Tao Glioblastoma multiforme (GBM) is the most common and devastating type of primary brain tumor, with a median survival time of only 15 months. Having a clinically applicable genetic biomarker would lead to a paradigm shift in precise diagnosis, personalized...
Fri Aug 21, 2020 03:00
Cancers, Vol. 12, Pages 2367: Breast-Specific Epigenetic Regulation of DeltaNp73 and Its Role in DNA-Damage-Response of BRCA1-Mutated Human Mammary Epithelial Cells Cancers doi: 10.3390/cancers12092367 Authors: Ayelet Avraham Susanna Feldman Sean Soonweng Cho Ayala Kol Lior Heler Emmanuela Riklin-Nahmias Avishay Sella Tamar Karni Tanir M. Allweis Saraswati Sukumar Ella Evron The function of BRCA1/2 proteins is essential for maintaining genomic integrity...
Fri Aug 21, 2020 03:00
Cancers, Vol. 12, Pages 2366: Computer-Aided Diagnosis in Multiparametric MRI of the Prostate: An Open-Access Online Tool for Lesion Classification with High Accuracy Cancers doi: 10.3390/cancers12092366 Authors: Stephan Ellmann Michael Schlicht Matthias Dietzel Rolf Janka Matthias Hammon Marc Saake Thomas Ganslandt Arndt Hartmann Frank Kunath Bernd Wullich Michael Uder Tobias Bäuerle Computer-aided diagnosis (CADx) approaches could help to objectify...
Fri Aug 21, 2020 03:00
Cancers, Vol. 12, Pages 2365: TILs Immunophenotype in Breast Cancer Predicts Local Failure and Overall Survival: Analysis in a Large Radiotherapy Trial with Long-Term Follow-Up Cancers doi: 10.3390/cancers12092365 Authors: Ewan Millar Lois Browne Iveta Slapetova Fei Shang Yuqi Ren Rachel Bradshaw Heather Ann Brauer Sandra O’Toole Julia Beretov Renee Whan Peter H. Graham Aim: To determine the prognostic significance of the immunophenotype of tumour-infiltrating...
Fri Aug 21, 2020 03:00
Cancers, Vol. 12, Pages 2364: Feasibility, Image Quality and Clinical Evaluation of Contrast-Enhanced Breast MRI Performed in a Supine Position Compared to the Standard Prone Position Cancers doi: 10.3390/cancers12092364 Authors: Alfonso Fausto Annarita Fanizzi Luca Volterrani Francesco Giuseppe Mazzei Claudio Calabrese Donato Casella Marco Marcasciano Raffaella Massafra Daniele La Forgia Maria Antonietta Mazzei Background: To assess the feasibility, image...
Fri Aug 21, 2020 03:00
Cancers, Vol. 12, Pages 2362: Uncommon Subtypes of Malignant Melanomas: A Review Based on Clinical and Molecular Perspectives Cancers doi: 10.3390/cancers12092362 Authors: Matías Chacón Yanina Pfluger Martín Angel Federico Waisberg Diego Enrico Malignant melanoma represents the most aggressive type of skin cancer. Modern therapies, including targeted agents and immune checkpoint inhibitors, have changed the dismal prognosis that characterized this disease. However, most evidence...
Fri Aug 21, 2020 03:00
Cancers, Vol. 12, Pages 2363: Upregulation of DR5 and Downregulation of Survivin by IITZ-01, Lysosomotropic Autophagy Inhibitor, Potentiates TRAIL-Mediated Apoptosis in Renal Cancer Cells via Ubiquitin-Proteasome Pathway Cancers doi: 10.3390/cancers12092363 Authors: Sk Abrar Shahriyar Seung Un Seo Kyoung-jin Min Peter Kubatka Do Sik Min Jong-Soo Chang Dong Eun Kim Seon Min Woo Taeg Kyu Kwon Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selectively...
Fri Aug 21, 2020 03:00
Cancers, Vol. 12, Pages 2361: Circulating Tumor Cells: From the Laboratory to the Cancer Clinic Cancers doi: 10.3390/cancers12092361 Authors: Ruchi Agashe Razelle Kurzrock Circulating tumor cells (CTCs) are cells that are shed from tumors into the bloodstream. Cell enrichment and isolation technology as well as molecular profiling via next-generation sequencing have allowed for a greater understanding of tumor cancer biology via the interrogation of CTCs. CTC detection can be used...
Fri Aug 21, 2020 03:00
Cells, Vol. 9, Pages 1948: Loganin Attenuates High Glucose-Induced Schwann Cells Pyroptosis by Inhibiting ROS Generation and NLRP3 Inflammasome Activation Cells doi: 10.3390/cells9091948 Authors: Cheng Chu Chen Hsieh Chang Dai Wu Diabetic peripheral neuropathy (DPN) is caused by hyperglycemia, which induces oxidative stress and inflammatory responses that damage nerve tissue. Excessive generation of reactive oxygen species (ROS) and NOD-like receptor protein...
Sun Aug 23, 2020 03:00
Cells, Vol. 9, Pages 1947: Molecular and Mechanobiological Pathways Related to the Physiopathology of FPLD2 Cells doi: 10.3390/cells9091947 Authors: Alice-Anaïs Varlet Emmanuèle Helfer Catherine Badens Laminopathies are rare and heterogeneous diseases affecting one to almost all tissues, as in Progeria, and sharing certain features such as metabolic disorders and a predisposition to atherosclerotic cardiovascular diseases. These two features are the main characteristics of the...
Sun Aug 23, 2020 03:00
Cells, Vol. 9, Pages 1943: Fructans Are Differentially Distributed in Root Tissues of Asparagus Cells doi: 10.3390/cells9091943 Authors: Katja Witzel Andrea Matros Inulin- and neoseries-type fructans [fructooligosaccharides (FOS) and fructopolysaccharides] accumulate in storage roots of asparagus (Asparagus officinalis L.), which continue to grow throughout the lifespan of this perennial plant. However, little is known about the storage of fructans at the spatial level in planta,...
Sat Aug 22, 2020 03:00
Cells, Vol. 9, Pages 1944: The Expressions of TSLP, IL-33, and IL-17A in Monocyte Derived Dendritic Cells from Asthma and COPD Patients are Related to Epithelial–Macrophage Interactions Cells doi: 10.3390/cells9091944 Authors: Magdalena Paplinska-Goryca Paulina Misiukiewicz-Stepien Malgorzata Proboszcz Patrycja Nejman-Gryz Katarzyna Gorska Rafal Krenke Background. The cross-talk between the external and internal environment in the respiratory tract involves macrophage/dendritic...
Sat Aug 22, 2020 03:00
Cells, Vol. 9, Pages 1946: Glycan Node Analysis of Plasma-Derived Extracellular Vesicles Cells doi: 10.3390/cells9091946 Authors: Sierra A. Walker Jesús S. Aguilar Díaz De león Sara Busatto Gregory A. Wurtz Abba C. Zubair Chad R. Borges Joy Wolfram Blood plasma is a readily accessible source of extracellular vesicles (EVs), i.e., cell-secreted nanosized carriers that contain various biomolecules, including glycans. Previous studies have demonstrated that glycans play...
Sat Aug 22, 2020 03:00
Cells, Vol. 9, Pages 1942: Y-Box Binding Protein 1 Expression in Trophoblast Cells Promotes Fetal and Placental Development Cells doi: 10.3390/cells9091942 Authors: Nicole Meyer Anne Schumacher Urs Coenen Katja Woidacki Hannah Schmidt Jonathan A. Lindquist Peter R. Mertens Ana C. Zenclussen Y-box binding protein 1 (YB-1) is pivotal for the regulation of cancerogenesis and inflammation. However, its involvement in pregnancy processes such as fetal and placental development...
Sat Aug 22, 2020 03:00
Cells, Vol. 9, Pages 1945: Role of Jagged1-mediated Notch Signaling Activation in the Differentiation and Stratification of the Human Limbal Epithelium Cells doi: 10.3390/cells9091945 Authors: Sheyla González Maximilian Halabi David Ju Matthew Tsai Sophie X. Deng The Notch signaling pathway plays a key role in proliferation and differentiation. We investigated the effect of Jagged 1 (Jag1)-mediated Notch signaling activation in the human limbal stem/progenitor cell (LSC)...
Sat Aug 22, 2020 03:00
Cells, Vol. 9, Pages 1940: AMPK-Dependent Mechanisms but Not Hypothalamic Lipid Signaling Mediates GH-Secretory Responses to GHRH and Ghrelin Cells doi: 10.3390/cells9091940 Authors: María J. Vázquez Marta G. Novelle Francisca Rodríguez-Pacheco Ricardo Lage Luis Varela Miguel López Leonor Pinilla Manuel Tena-Sempere Carlos Diéguez GH (growth hormone) secretion/action is modulated by alterations in energy homeostasis, such as malnutrition and obesity. Recent data...
Fri Aug 21, 2020 03:00
Cells, Vol. 9, Pages 1939: Modulation of Human Adipose Stem Cells’ Neurotrophic Capacity Using a Variety of Growth Factors for Neural Tissue Engineering Applications: Axonal Growth, Transcriptional, and Phosphoproteomic Analyses In Vitro Cells doi: 10.3390/cells9091939 Authors: Katharina M. Prautsch Alexander Schmidt Viola Paradiso Dirk J. Schaefer Raphael Guzman Daniel F. Kalbermatten Srinivas Madduri We report on a potential strategy involving the exogenous neurotrophic...
Fri Aug 21, 2020 03:00
Cells, Vol. 9, Pages 1936: Tsg101 Is Involved in the Sorting and Re-Distribution of Glucose Transporter-4 to the Sarcolemma Membrane of Cardiac Myocytes Cells doi: 10.3390/cells9091936 Authors: Kobina Essandoh Shan Deng Xiaohong Wang Yutian Li Qianqian Li Xingjiang Mu Tianqing Peng Guo-Chang Fan Cardiac cells can adapt to pathological stress-induced energy crisis by shifting from fatty acid oxidation to glycolysis. However, the use of glucose-insulin-potassium (GIK)...
Fri Aug 21, 2020 03:00
Cells, Vol. 9, Pages 1941: In Vivo TSPO Signal and Neuroinflammation in Alzheimer’s Disease Cells doi: 10.3390/cells9091941 Authors: Tournier Tsartsalis Ceyzériat Garibotto Millet In the last decade, positron emission tomography (PET) and single-photon emission computed tomography (SPECT) in in vivo imaging has attempted to demonstrate the presence of neuroinflammatory reactions by measuring the 18 kDa translocator protein (TSPO) expression in many diseases of the central...
Fri Aug 21, 2020 03:00
Cells, Vol. 9, Pages 1938: Detecting Interactive Gene Groups for Single-Cell RNA-Seq Data Based on Co-Expression Network Analysis and Subgraph Learning Cells doi: 10.3390/cells9091938 Authors: Xiucai Ye Weihang Zhang Yasunori Futamura Tetsuya Sakurai High-throughput sequencing technologies have enabled the generation of single-cell RNA-seq (scRNA-seq) data, which explore both genetic heterogeneity and phenotypic variation between cells. Some methods have been proposed to detect...
Fri Aug 21, 2020 03:00
Cells, Vol. 9, Pages 1937: Arabidopsis thaliana cbp80, c2h2, and flk Knockout Mutants Accumulate Increased Amounts of Circular RNAs Cells doi: 10.3390/cells9091937 Authors: Anna Philips Katarzyna Nowis Michal Stelmaszczuk Jan Podkowiński Luiza Handschuh Paulina Jackowiak Marek Figlerowicz Circular RNAs (circRNAs) are the products of the non-canonical splicing of pre-mRNAs. In contrast to humans and animals, our knowledge of the biogenesis and function of circRNAs in...
Fri Aug 21, 2020 03:00
Cells, Vol. 9, Pages 1933: Phosphorus Feast and Famine in Cyanobacteria: Is Luxury Uptake of the Nutrient Just a Consequence of Acclimation to Its Shortage? Cells doi: 10.3390/cells9091933 Authors: Alexei Solovchenko Olga Gorelova Olga Karpova Irina Selyakh Larisa Semenova Olga Chivkunova Olga Baulina Elizaveta Vinogradova Tatiana Pugacheva Pavel Scherbakov Svetlana Vasilieva Alexandr Lukyanov Elena Lobakova To cope with fluctuating phosphorus (P)...
Fri Aug 21, 2020 03:00
Cells, Vol. 9, Pages 1934: Molecular Genetics and Functional Analysis Implicate CDKN2BAS1-CDKN2B Involvement in POAG Pathogenesis Cells doi: 10.3390/cells9091934 Authors: Sonika Rathi Ian Danford Harini V. Gudiseva Lana Verkuil Maxwell Pistilli Sushma Vishwakarma Inderjeet Kaur Tarjani Dave Joan M. O’Brien Venkata R. M. Chavali The genes in the 9p21 locus (CDKN2B-AS1 & CDKN2B) are widely associated with Primary open-angle glaucoma (POAG). However, the...
Fri Aug 21, 2020 03:00
Cells, Vol. 9, Pages 1935: Ischemia-Like Stress Conditions Stimulate Trophic Activities of Adipose-Derived Stromal/Stem Cells Cells doi: 10.3390/cells9091935 Authors: Julia Bachmann Elias Ehlert Matthias Becker Christoph Otto Katrin Radeloff Torsten Blunk Petra Bauer-Kreisel Adipose-derived stromal/stem cells (ASCs) have been shown to exert regenerative functions, which are mainly attributed to the secretion of trophic factors. Upon transplantation, ASCs are facing...
Fri Aug 21, 2020 03:00
Cells, Vol. 9, Pages 1932: Wide Biological Role of Hydroxytyrosol: Possible Therapeutic and Preventive Properties in Cardiovascular Diseases Cells doi: 10.3390/cells9091932 Authors: Chiara D’Angelo Sara Franceschelli José Luis Quiles Lorenza Speranza The growing incidence of cardiovascular disease (CVD) has promoted investigations of natural molecules that could prevent and treat CVD. Among these, hydroxytyrosol, a polyphenolic compound of olive oil, is well known for its antioxidant,...
Fri Aug 21, 2020 03:00
Cells, Vol. 9, Pages 1931: Uptake and Fate of Extracellular Membrane Vesicles: Nucleoplasmic Reticulum-Associated Late Endosomes as a New Gate to Intercellular Communication Cells doi: 10.3390/cells9091931 Authors: Denis Corbeil Mark F. Santos Jana Karbanová Thomas Kurth Germana Rappa Aurelio Lorico Extracellular membrane vesicles (EVs) are emerging as new vehicles in intercellular communication, but how the biological information contained in EVs is shared between cells...
Fri Aug 21, 2020 03:00
Cells, Vol. 9, Pages 1930: Estradiol Induces Epithelial to Mesenchymal Transition of Human Glioblastoma Cells Cells doi: 10.3390/cells9091930 Authors: Ana M. Hernández-Vega Aylin Del Moral-Morales Carmen J. Zamora-Sánchez Ana G. Piña-Medina Aliesha González-Arenas Ignacio Camacho-Arroyo The mesenchymal phenotype of glioblastoma multiforme (GBM), the most frequent and malignant brain tumor, is associated with the worst prognosis. The epithelial–mesenchymal transition...
Fri Aug 21, 2020 03:00
Chemosensors, Vol. 8, Pages 76: Monitoring Corrosion Processes via Visible Fiber-Optic Evanescent Wave Sensor Chemosensors doi: 10.3390/chemosensors8030076 Authors: Türkmen Krug Mizaikoff Ferrous objects, especially those that are additionally exposed to harsh environments, e.g., high humidity, have the common problem of suffering aggressive corrosion processes. Without a precaution, this leads in many cases to a limited functionality followed by treatment steps, and expensive...
Sun Aug 23, 2020 03:00
Chemosensors, Vol. 8, Pages 75: Determination of Volatile Organic Compounds in Water by Attenuated Total Reflection Infrared Spectroscopy and Diamond-Like Carbon Coated Silicon Wafers Chemosensors doi: 10.3390/chemosensors8030075 Authors: Dettenrieder Türkmen Mattsson Österlund Karlsson Mizaikoff Volatile organic compounds (VOCs) are one of the most commonly detected contaminants in water. The occurrence is mainly in gasoline and other petroleum-based products, fumigants,...
Sun Aug 23, 2020 03:00
Chemosensors, Vol. 8, Pages 74: Electrochemical Methods and (Bio) Sensors for Rosmarinic Acid Investigation Chemosensors doi: 10.3390/chemosensors8030074 Authors: Iulia Gabriela David Dana Elena Popa Mihaela Buleandră Mihaela Carmen Cheregi Rosmarinic acid (RA) is an important bioactive phenolic acid with significant biochemical activities, including the antioxidant one. It is widely found in plants of the families Lamiaceae and Boraginaceae and has many uses in the food, pharmaceutical...
Sat Aug 22, 2020 03:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου