Antibiotics, Vol. 9, Pages 532: Microbial Composition of Oral Biofilms after Visible Light and Water-Filtered Infrared a Radiation (VIS+wIRA) in Combination with Indocyanine Green (ICG) as Photosensitizer Antibiotics doi: 10.3390/antibiotics9090532 Authors: Thomas Burchard Lamprini Karygianni Elmar Hellwig Annette Wittmer Ali Al-Ahmad In view of increasing antibiotic resistance, antimicrobial photodynamic therapy (aPDT) is an alternative treatment method used to eradicate...
Antibiotics, Vol. 9, Pages 530: Novel Antimicrobial Peptide from Temporin L in The Treatment of Staphylococcus pseudintermedius and Malassezia pachydermatis in Polymicrobial Inter-Kingdom Infection Antibiotics doi: 10.3390/antibiotics9090530 Authors: Rosa Bellavita Adriana Vollaro Maria Rosaria Catania Francesco Merlino Luisa De Martino Francesca Paola Nocera Marina DellaGreca Francesca Lembo Paolo Grieco Elisabetta Buommino Interkingdom polymicrobial diseases...
Antibiotics, Vol. 9, Pages 531: Involvement of hpap2 and dgkA Genes in Colistin Resistance Mediated by mcr Determinants Antibiotics doi: 10.3390/antibiotics9090531 Authors: Alejandro Gallardo María Ugarte-Ruiz Marta Hernández Pedro Miguela-Villoldo David Rodríguez-Lázaro Lucas Domínguez Alberto Quesada Plasmid-mediated colistin resistance (mcr) determinants are challenging the efficacy of polymyxins against Gram-negative pathogens. Among 10 mcr genes described so far,...
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Antioxidants, Vol. 9, Pages 781: Biochemical Evaluation of the Antioxidant Effects of Hydroxytyrosol on Pancreatitis-Associated Gut Injury Antioxidants doi: 10.3390/antiox9090781 Authors: Fusco Cordaro Siracusa D’Amico Genovese Gugliandolo Peritore Crupi Impellizzeri Cuzzocrea Paola Acute pancreatitis is a severe abdominal pathology often associated with several complications including gut dysfunction. Oxidative stress is one of the most important...
Antioxidants, Vol. 9, Pages 780: The Circadian Hormone Melatonin Inhibits Morphine-Induced Tolerance and Inflammation via the Activation of Antioxidative Enzymes Antioxidants doi: 10.3390/antiox9090780 Authors: Ing-Jung Chen Chih-Ping Yang Sheng-Hsiung Lin Chang-Mei Lai Chih-Shung Wong Opioids are commonly prescribed for clinical pain management; however, dose-escalation, tolerance, dependence, and addiction limit their usability for long-term chronic pain. The associated...
Antioxidants, Vol. 9, Pages 779: The BACH1/Nrf2 Axis in Brain in Down Syndrome and Transition to Alzheimer Disease-Like Neuropathology and Dementia Antioxidants doi: 10.3390/antiox9090779 Authors: Perluigi Tramutola Pagnotta Barone Butterfield Down syndrome (DS) is the most common genetic cause of intellectual disability that is associated with an increased risk to develop early-onset Alzheimer-like dementia (AD). The brain neuropathological features include alteration...
Antioxidants, Vol. 9, Pages 776: Ethanol-Induced Oxidative Stress Modifies Inflammation and Angiogenesis Biomarkers in Retinal Pigment Epithelial Cells (ARPE-19): Role of CYP2E1 and its Inhibition by Antioxidants Antioxidants doi: 10.3390/antiox9090776 Authors: Natalia Martinez-Gil Lorena Vidal-Gil Miguel Flores-Bellver Rosa Maisto Javier Sancho-Pelluz Manuel Diaz-Llopis Jorge M. Barcia Francisco J. Romero The retinal pigment epithelium (RPE) plays a key role in...
Antioxidants, Vol. 9, Pages 778: Redox Status, Dose and Antioxidant Intake in Healthcare Workers Occupationally Exposed to Ionizing Radiation Antioxidants doi: 10.3390/antiox9090778 Authors: Natividad Sebastià Lorena Olivares-González Alegría Montoro Joan-Francesc Barquinero Antonio José Canyada-Martinez David Hervás Pilar Gras Juan Ignacio Villaescusa Luis Martí-Bonmatí Bianca Tabita Muresan José Miguel Soriano Juan Manuel Campayo Joaquin Andani Oscar...
Antioxidants, Vol. 9, Pages 777: Oxidative Stress and Inflammation Induced by Waterpipe Tobacco Smoking Despite Possible Protective Effects of Exercise Training: A Review of the Literature Antioxidants doi: 10.3390/antiox9090777 Authors: Behzad Taati Hamid Arazi Katsuhiko Suzuki The prevalence of waterpipe tobacco smoking (WTS), which is also known as ghalyan, shisha or hookah, is increasing rapidly around the world, especially among youth. Growing interest in this form of tobacco...
Antioxidants, Vol. 9, Pages 775: In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with IX and XII hCA Inhibition Antioxidants doi: 10.3390/antiox9090775 Authors: Giosuè Costa Annalisa Maruca Roberta Rocca Francesca Alessandra Ambrosio Emanuela Berrino Fabrizio Carta Francesco Mesiti Alessandro Salatino Delia Lanzillotta Francesco Trapasso Anna Artese Stefano Alcaro Claudiu T. Supuran The tumor-associated isoenzymes...
Antioxidants, Vol. 9, Pages 774: Human Relaxin-2 (Serelaxin) Attenuates Oxidative Stress in Cardiac Muscle Cells Exposed In Vitro to Hypoxia–Reoxygenation. Evidence for the Involvement of Reduced Glutathione Up-Regulation Antioxidants doi: 10.3390/antiox9090774 Authors: Silvia Nistri Claudia Fiorillo Matteo Becatti Daniele Bani Serelaxin (RLX) designates the pharmaceutical form of the human natural hormone relaxin-2 that has been shown to markedly reduce tissue and cell damage...
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Atmosphere, Vol. 11, Pages 892: Changes in the Seasonality of Ethiopian Highlands Climate and Implications for Crop Growth Atmosphere doi: 10.3390/atmos11090892 Authors: Gashaw Bimrew Tarkegn Mark R. Jury Rain-fed agriculture in North-West (NW) Ethiopia is seasonally modulated, and our objective is to isolate past and future trends that influence crop growth. Statistical methods are applied to gauge-interpolated, reanalysis, and satellite data to evaluate changes in the annual cycle...
Atmosphere, Vol. 11, Pages 890: Application of Positive Matrix Factorization Receptor Model for Source Identification of PM10 in the City of Sofia, Bulgaria Atmosphere doi: 10.3390/atmos11090890 Authors: Hristova Veleva Georgieva Branzov The Positive Matrix Factorization (PMF) receptor model is used for identification of source contributions to PM10 sampled during the period January 2019–January 2020 in Sofia. More than 200 filters were analyzed by X-Ray Fluorescence...
Atmosphere, Vol. 11, Pages 891: Characterization of Spatio-Temporal Trends and Periodicity of Precipitation over Malawi during 1979–2015 Atmosphere doi: 10.3390/atmos11090891 Authors: Edwin Tadeyo Dan Chen Brian Ayugi Chunzhen Yao Precipitation remains the key climatic parameter in sub-Saharan Africa, as it drives the economy through rain-fed agricultural production. Malawi is one of the countries most susceptible to the impacts of climate change and variability. This paper...
Atmosphere, Vol. 11, Pages 889: 501 Years of Spring Precipitation History for the Semi-Arid Northern Iran Derived from Tree-Ring δ18O Data Atmosphere doi: 10.3390/atmos11090889 Authors: Zeynab Foroozan Jussi Grießinger Kambiz Pourtahmasi Achim Bräuning In semi-arid regions of the world, knowledge about the long-term hydroclimate variability is essential to analyze and evaluate the impact of current climate change on ecosystems. We present the first tree-ring δ18O based...
Atmosphere, Vol. 11, Pages 888: Investigating the Impact of High-Resolution Land–Sea Masks on Hurricane Forecasts in HWRF Atmosphere doi: 10.3390/atmos11090888 Authors: Zaizhong Ma Bin Liu Avichal Mehra Ali Abdolali Andre van der Westhuysen Saeed Moghimi Sergey Vinogradov Zhan Zhang Lin Zhu Keqin Wu Roshan Shrestha Anil Kumar Vijay Tallapragada Nicole Kurkowski Realistic wind information is critical for accurate forecasts of landfalling hurricanes....
Atmosphere, Vol. 11, Pages 887: The Impact of Foreign SO2 Emissions on Aerosol Direct Radiative Effects in South Korea Atmosphere doi: 10.3390/atmos11090887 Authors: Jung-Woo Yoo Wonbae Jeon Hwa Woon Lee Jeonghyeok Mun Soon-Hwan Lee Soon-Young Park This study examined the impact of foreign SO2 emission changes on the aerosol direct radiative effects (ADRE) in South Korea. Simulations that applied basic emissions (BASE) and simulations that applied reduced SO2 emissions...
Atmosphere, Vol. 11, Pages 886: Differential Influences of Teleconnections from the Indian and Pacific Oceans on Rainfall Variability in Southeast Asia Atmosphere doi: 10.3390/atmos11090886 Authors: Abdul Azim Amirudin Ester Salimun Fredolin Tangang Liew Juneng Muhamad Zuhairi This study investigates the individual and combined impacts of El Niño and the positive Indian Ocean Dipole (IOD) on the Southeast Asia (SEA) rainfall variability. Using composite and partial...
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Biology, Vol. 9, Pages 241: Model and Data Concur and Explain the Coexistence of Two Very Distinct Animal Behavioral Types Biology doi: 10.3390/biology9090241 Authors: Jordi Moya-Laraño Rubén Rabaneda-Bueno Emily Morrison Philip H. Crowley Behaviors may enhance fitness in some situations while being detrimental in others. Linked behaviors (behavioral syndromes) may be central to understanding the maintenance of behavioral variability in natural populations. The spillover hypothesis...
Biology, Vol. 9, Pages 242: Metabolic Responses of Carotenoid and Cordycepin Biosynthetic Pathways in Cordyceps militaris under Light-Programming Exposure through Genome-Wide Transcriptional Analysis Biology doi: 10.3390/biology9090242 Authors: Roypim Thananusak Kobkul Laoteng Nachon Raethong Yu Zhang Wanwipa Vongsangnak Cordyceps militaris is currently exploited for commercial production of specialty products as its biomass constituents are enriched in bioactive compounds,...
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Biomedicines, Vol. 8, Pages 303: Pharmacovigilance of Biopharmaceuticals in Rheumatic Diseases, Adverse Events, Evolution, and Perspective: An Overview Biomedicines doi: 10.3390/biomedicines8090303 Authors: Sandra Rodríguez Andrés Muñoz Rosa-Helena Bustos Diego Jaimes Since we have gained an understanding of the immunological pathophysiology of rheumatic diseases such as rheumatoid arthritis and systemic lupus erythematosus, treatment based on biological drugs has become a fundamental...
Biomedicines, Vol. 8, Pages 302: An In Vitro Barrier Model of the Human Submandibular Salivary Gland Epithelium Based on a Single Cell Clone of Cell Line HTB-41: Establishment and Application for Biomarker Transport Studies Biomedicines doi: 10.3390/biomedicines8090302 Authors: Grace C. Lin Merima Smajlhodzic Anna-Maria Bandian Heinz-Peter Friedl Tamara Leitgeb Sabrina Oerter Kerstin Stadler Ulrich Giese Johannes R. Peham Lynne Bingle Winfried Neuhaus The...
Biomedicines, Vol. 8, Pages 301: Sulfated Polysaccharides from Marine Algae as a Basis of Modern Biotechnologies for Creating Wound Dressings: Current Achievements and Future Prospects Biomedicines doi: 10.3390/biomedicines8090301 Authors: Andryukov Besednova Kuznetsova Zaporozhets Ermakova Zvyagintseva Chingizova Gazha Smolina Wound healing involves a complex cascade of cellular, molecular, and biochemical responses and signaling processes. It consists...
Biomedicines, Vol. 8, Pages 298: Usefulness of Different Imaging Modalities in Evaluation of Patients with Non-Alcoholic Fatty Liver Disease Biomedicines doi: 10.3390/biomedicines8090298 Authors: Karolina Grąt Michał Grąt Olgierd Rowiński Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are becoming some of the major health problems in well-developed countries, together with the increasing prevalence of obesity, metabolic syndrome, and all of their...
Biomedicines, Vol. 8, Pages 299: A New Islet Transplantation Method Combining Mesenchymal Stem Cells with Recombinant Peptide Pieces, Microencapsulated Islets, and Mesh Bags Biomedicines doi: 10.3390/biomedicines8090299 Authors: Ryo Kogawa Kentaro Nakamura Yusuke Mochizuki Microencapsulated islet transplantation was widely studied as a promising treatment for type 1 diabetes mellitus. However, micro-encapsulated islet transplantation has the following problems—early dysfunction...
Biomedicines, Vol. 8, Pages 300: Bioabsorbable Osteofixation Materials for Maxillofacial Bone Surgery: A Review on Polymers and Magnesium-Based Materials Biomedicines doi: 10.3390/biomedicines8090300 Authors: Sung-Woon On Seoung-Won Cho Soo-Hwan Byun Byoung-Eun Yang Clinical application of osteofixation materials is essential in performing maxillofacial surgeries requiring rigid fixation of bone such as trauma surgery, orthognathic surgery, and skeletal reconstruction. In addition...
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Biomimetics, Vol. 5, Pages 39: Biomimetic Catalysts Based on Au@ZnO–Graphene Composites for the Generation of Hydrogen by Water Splitting Biomimetics doi: 10.3390/biomimetics5030039 Authors: Abniel Machín Juan C. Arango Kenneth Fontánez María Cotto José Duconge Loraine Soto-Vázquez Edgar Resto Florian Ion Tiberiu Petrescu Carmen Morant Francisco Márquez For some decades, the scientific community has been looking for alternatives to the use of fossil fuels that...
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Biomolecules, Vol. 10, Pages 1226: Characterization of In Vivo Function(s) of Members of the Plant Mitochondrial Carrier Family Biomolecules doi: 10.3390/biom10091226 Authors: Adriano Nunes-Nesi João Henrique F. Cavalcanti Alisdair R. Fernie Although structurally related, mitochondrial carrier family (MCF) proteins catalyze the specific transport of a range of diverse substrates including nucleotides, amino acids, dicarboxylates, tricarboxylates, cofactors, vitamins, phosphate...
Biomolecules, Vol. 10, Pages 1224: Multiple Screening of Pesticides Toxicity in Zebrafish and Daphnia Based on Locomotor Activity Alterations Biomolecules doi: 10.3390/biom10091224 Authors: Akhlaq Hussain Gilbert Audira Nemi Malhotra Boontida Uapipatanakul Jung-Ren Chen Yu-Heng Lai Jong-Chin Huang Kelvin H.-C. Chen Hong-Thih Lai Chung-Der Hsiao Pesticides are widely used to eradicate insects, weed species, and fungi in agriculture. The half-lives of some pesticides...
Biomolecules, Vol. 10, Pages 1225: Canonical and Non-Canonical Roles of Connexin43 in Cardioprotection Biomolecules doi: 10.3390/biom10091225 Authors: Olga M. Rusiecka Jade Montgomery Sandrine Morel Daniela Batista-Almeida Raf Van Campenhout Mathieu Vinken Henrique Girao Brenda R. Kwak Since the mid-20th century, ischemic heart disease has been the world’s leading cause of death. Developing effective clinical cardioprotection strategies would make a significant...
Biomolecules, Vol. 10, Pages 1223: Elucidating the Inhibitory Effect of Resveratrol and Its Structural Analogs on Selected Nucleotide-Related Enzymes Biomolecules doi: 10.3390/biom10091223 Authors: Yifei Wu Tze-chen Hsieh Joseph M. Wu Xiaoxiao Wang Joshua S. Christopher Amanda H. Pham Justin David-Li Swaby Lei Lou Zhong-Ru Xie Resveratrol, the most widely studied natural phytochemical, has been shown to interact with different target proteins. Previous studies...
Biomolecules, Vol. 10, Pages 1222: Applications of Cytokinins in Horticultural Fruit Crops: Trends and Future Prospects Biomolecules doi: 10.3390/biom10091222 Authors: Aremu Fawole Makunga Masondo Moyo Buthelezi Amoo Spíchal Doležal Cytokinins (CKs) are a chemically diverse class of plant growth regulators, exhibiting wide-ranging actions on plant growth and development, hence their exploitation in agriculture for crop improvement and management. Their...
Biomolecules, Vol. 10, Pages 1221: PMEPA1 Gene Isoforms: A Potential Biomarker and Therapeutic Target in Prostate Cancer Biomolecules doi: 10.3390/biom10091221 Authors: Sharad Dobi Srivastava Srinivasan Li The identification of prostate transmembrane protein androgen induced 1 (PMEPA1), an androgen responsive gene, came initially from the studies of androgen regulatory gene networks in prostate cancer. It was soon followed by the documentation of the expression and functional...
Biomolecules, Vol. 10, Pages 1220: MDA-MB-231 Breast Cancer Cells Resistant to Pleurocidin-Family Lytic Peptides Are Chemosensitive and Exhibit Reduced Tumor-Forming Capacity Biomolecules doi: 10.3390/biom10091220 Authors: Ashley L. Hilchie Erin E. Gill Melanie R. Power Coombs Reza Falsafi Robert E. W. Hancock David W. Hoskin Direct-acting anticancer (DAA) peptides are cytolytic peptides that show promise as novel anticancer agents. DAA peptides bind to anionic molecules...
Biomolecules, Vol. 10, Pages 1218: Caveolae and Lipid Rafts in Endothelium: Valuable Organelles for Multiple Functions Biomolecules doi: 10.3390/biom10091218 Authors: Antonio Filippini Alessio D’Alessio Caveolae are flask-shaped invaginations of the plasma membrane found in numerous cell types and are particularly abundant in endothelial cells and adipocytes. The lipid composition of caveolae largely matches that of lipid rafts microdomains that are particularly enriched in cholesterol,...
Biomolecules, Vol. 10, Pages 1217: Foliar Spray of Fe-Asp Confers Better Drought Tolerance in Sunflower as Compared with FeSO4: Yield Traits, Osmotic Adjustment, and Antioxidative Defense Mechanisms Biomolecules doi: 10.3390/biom10091217 Authors: Qasim Ali Shafaqat Ali Mohamed A. El-Esawi Muhammad Rizwan Muhammad Azeem Abdullah Ijaz Hussain Rashida Perveen Mohamed A. El-Sheikh Mohammed Nasser Alyemeni Leonard Wijaya Different techniques are being employed to...
Biomolecules, Vol. 10, Pages 1219: Applications of Compounds from Coffee Processing By-Products Biomolecules doi: 10.3390/biom10091219 Authors: Amaia Iriondo-DeHond Maite Iriondo-DeHond María Dolores del Castillo To obtain the coffee beverage, approximately 90% of the edible parts of the coffee cherry are discarded as agricultural waste or by-products (cascara or husk, parchment, mucilage, silverskin and spent coffee grounds). These by-products are a potential source of nutrients...
Biomolecules, Vol. 10, Pages 1215: Peucedanum ostruthium Inhibits E-Selectin and VCAM-1 Expression in Endothelial Cells through Interference with NF-κB Signaling Biomolecules doi: 10.3390/biom10091215 Authors: Christoph Lammel Julia Zwirchmayr Jaqueline Seigner Judith M. Rollinger Rainer de Martin Twenty natural remedies traditionally used against different inflammatory diseases were probed for their potential to suppress the expression of the inflammatory markers E-selectin...
Biomolecules, Vol. 10, Pages 1216: The Influence of Nasturtium officinale R. Br. Agar and Agitated Microshoot Culture Media on Glucosinolate and Phenolic Acid Production, and Antioxidant Activity Biomolecules doi: 10.3390/biom10091216 Authors: Marta Klimek-Szczykutowicz Agnieszka Szopa Michał Dziurka Łukasz Komsta Michał Tomczyk Halina Ekiert This paper presents an optimization of conditions for microshoot cultures of Nasturtium officinale R. Br. (watercress). Variants...
Biomolecules, Vol. 10, Pages 1214: Study of Biomolecular Interactions of Mitochondrial Proteins Related to Alzheimer’s Disease: Toward Multi-Interaction Biomolecular Processes Biomolecules doi: 10.3390/biom10091214 Authors: Erika Hemmerová Tomáš Špringer Zdeňka Krištofiková Jiří Homola Progressive mitochondrial dysfunction due to the accumulation of amyloid beta (Aβ) peptide within the mitochondrial matrix represents one of the key characteristics of Alzheimer’s...
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Biosensors, Vol. 10, Pages 104: Poly(9H-carbazole) as a Organic Semiconductor for Enzymatic and Non-Enzymatic Glucose Sensors Biosensors doi: 10.3390/bios10090104 Authors: Bagdžiūnas Palinauskas Organic semiconductors and conducting polymers are the most promising next-generation conducting materials for electrochemical biosensors as the greener and cheaper alternative for electrodes based on transition metals or their oxides. Therefore, polycarbazole as the organic semiconducting...
Biosensors, Vol. 10, Pages 103: A French–Greek Cross-Site Comparison Study of the Use of Automatic Video Analyses for the Assessment of Autonomy in Dementia Patients Biosensors doi: 10.3390/bios10090103 Authors: Anastasios Karakostas Alexandra König Carlos Fernando Crispim-Junior François Bremond Alexandre Derreumaux Ioulietta Lazarou Ioannis Kompatsiaris Magda Tsolaki Philippe Robert Background: At present, the assessment of autonomy in daily living activities,...
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Brain Sciences, Vol. 10, Pages 581: Proximal Upper Limb Sensorimotor Integration in Response to Novel Motor Skill Acquisition Brain Sciences doi: 10.3390/brainsci10090581 Authors: Sinead O’Brien Danielle Andrew Mahboobeh Zabihhosseinian Paul Yielder Bernadette Murphy Previous studies have shown significant changes in cortical and subcortical evoked potential activity levels in response to motor training with the distal upper-limb muscles. However, no studies to date have...
Brain Sciences, Vol. 10, Pages 582: The Effects of Gradual Change in Head Positioning on the Relationship between Systemic and Cerebral Haemodynamic Parameters in Healthy Controls and Acute Ischaemic Stroke Patients Brain Sciences doi: 10.3390/brainsci10090582 Authors: Eloise Sands Louvinia Wong Man Y. Lam Ronney B. Panerai Thompson G. Robinson Jatinder S. Minhas (1) Background: Larger blood pressure variability (BPv) in the first 3 h post-stroke onset increases pathophysiological...
Brain Sciences, Vol. 10, Pages 579: Obesity is Associated with Reduced Plasticity of the Human Motor Cortex Brain Sciences doi: 10.3390/brainsci10090579 Authors: Sophia X. Sui Michael C. Ridding Brenton Hordacre Obesity is characterised by excessive body fat and is associated with several detrimental health conditions, including cardiovascular disease and diabetes. There is some evidence that people who are obese have structural and functional brain alterations and cognitive deficits....
Brain Sciences, Vol. 10, Pages 580: Age-Dependency of Neurite Outgrowth in Postnatal Mouse Cochlear Spiral Ganglion Explants Brain Sciences doi: 10.3390/brainsci10090580 Authors: Claudia Frick Stefan Fink Dominik Schmidbauer Francis Rousset Holger Eickhoff Anke Tropitzsch Benedikt Kramer Pascal Senn Rudolf Glueckert Helge Rask-Andersen Karl-Heinz Wiesmüller Hubert Löwenheim Marcus Müller Background: The spatial gap between cochlear implants (CIs) and...
Brain Sciences, Vol. 10, Pages 578: Leveraging Neural Networks in Preclinical Alcohol Research Brain Sciences doi: 10.3390/brainsci10090578 Authors: Lauren C. Smith Adam Kimbrough Alcohol use disorder is a pervasive healthcare issue with significant socioeconomic consequences. There is a plethora of neural imaging techniques available at the clinical and preclinical level, including magnetic resonance imaging and three-dimensional (3D) tissue imaging techniques. Network-based approaches...
Brain Sciences, Vol. 10, Pages 577: The Use of Electrochemical Voltammetric Techniques and High-Pressure Liquid Chromatography to Evaluate Conjugation Efficiency of Multiple Sclerosis Peptide-Carrier Conjugates Brain Sciences doi: 10.3390/brainsci10090577 Authors: Efstathios Deskoulidis Sousana Petrouli Vasso Apostolopoulos John Matsoukas Emmanuel Topoglidis Recent studies have shown the ability of electrochemical methods to sense and determine, even at very low concentrations,...
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Cancers, Vol. 12, Pages 2382: Angiogenesis Inhibition in Prostate Cancer: An Update Cancers doi: 10.3390/cancers12092382 Authors: Sarkar Goswami Basu Chakroborty Prostate cancer (PCa), like all other solid tumors, relies on angiogenesis for growth, progression, and the dissemination of tumor cells to other parts of the body. Despite data from in vitro and in vivo preclinical studies, as well as human specimen studies indicating the crucial role played by angiogenesis in...
Cancers, Vol. 12, Pages 2388: HPV-Induced Oropharyngeal Cancer and the Role of the E7 Oncoprotein Detection via Brush Test Cancers doi: 10.3390/cancers12092388 Authors: Wegene Borena Volker H. Schartinger Jozsef Dudas Julia Ingruber Maria C. Greier Teresa B. Steinbichler Johannes Laimer Heribert Stoiber Herbert Riechelmann Barbara Kofler Background: High risk human papillomavirus (hr-HPV)-associated oropharyngeal cancers (OPCs) are characterized by significantly...
Cancers, Vol. 12, Pages 2386: Genetic Counseling for Hereditary Gastric and Pancreatic Cancer in High-Risk Gastrointestinal Cancer Clinics: An Effective Strategy Cancers doi: 10.3390/cancers12092386 Authors: Joan Llach Lorena Moreno Ariadna Sánchez Cristina Herrera-Pariente Teresa Ocaña Miriam Cuatrecasas Liseth Rivero-Sánchez Rebeca Moreira Mireia Díaz Gerhard Jung Maria Pellisé Antoni Castells Francesc Balaguer Sabela Carballal Leticia Moreira ...
Cancers, Vol. 12, Pages 2387: Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Surface Malignancies: Learning Curve Based on Surgical and Oncological Outcomes Cancers doi: 10.3390/cancers12092387 Authors: Mielko Rawicz-Pruszyński Sędłak Gęca Kwietniewska Polkowski Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is a complex procedure with a steep learning curve (LC). The comprehensive complication...
Cancers, Vol. 12, Pages 2385: Proteotoxic Stress and Cell Death in Cancer Cells Cancers doi: 10.3390/cancers12092385 Authors: Claudio Brancolini Luca Iuliano To maintain proteostasis, cells must integrate information and activities that supervise protein synthesis, protein folding, conformational stability, and also protein degradation. Extrinsic and intrinsic conditions can both impact normal proteostasis, causing the appearance of proteotoxic stress. Initially, proteotoxic stress...
Cancers, Vol. 12, Pages 2383: Marker Identification of the Grade of Dysplasia of Intraductal Papillary Mucinous Neoplasm in Pancreatic Cyst Fluid by Quantitative Proteomic Profiling Cancers doi: 10.3390/cancers12092383 Authors: Misol Do Hongbeom Kim Dongyoon Shin Joonho Park Haeryoung Kim Youngmin Han Jin-Young Jang Youngsoo Kim The incidence of patients with pancreatic cystic lesions, particularly intraductal papillary mucinous neoplasm (IPMN), is increasing. Current...
Cancers, Vol. 12, Pages 2384: S1 versus Doublet Regimens as Adjuvant Chemotherapy in Patients with Advanced Gastric Cancer after Radical Surgery with D2 Dissection—A Propensity Score Matching Analysis Cancers doi: 10.3390/cancers12092384 Authors: Meng-Che Hsieh Shih-Ho Wang Ching-Ting Wei Chung-Yen Chen Yen-Yang Chen Sung-Nan Pei Yu-Fen Tsai Kun-Ming Rau Background: Fluoropyrimidine- and platinum-based doublet regimen is the standard treatment of adjuvant chemotherapy...
Cancers, Vol. 12, Pages 2381: Murine Models of Myelofibrosis Cancers doi: 10.3390/cancers12092381 Authors: Sebastien Jacquelin Frederike Kramer Ann Mullally Steven W. Lane Myelofibrosis (MF) is subtype of myeloproliferative neoplasm (MPN) characterized by a relatively poor prognosis in patients. Understanding the factors that drive MF pathogenesis is crucial to identifying novel therapeutic approaches with the potential to improve patient care. Driver mutations in three main...
Cancers, Vol. 12, Pages 2380: An Integrative Omics Approach Reveals Involvement of BRCA1 in Hepatic Metastatic Progression of Colorectal Cancer Cancers doi: 10.3390/cancers12092380 Authors: Gerovska Larrinaga Solano-Iturria Márquez García Gallastegi Khatib Poschmann Stühler Armesto Lawrie Badiola Araúzo-Bravo : (1) Background & Aims: The roles of different cells in the tumor microenvironment (TME) are critical to the metastatic process....
Cancers, Vol. 12, Pages 2379: Thrombocytosis as a Biomarker in Type II, Non-Endometrioid Endometrial Cancer Cancers doi: 10.3390/cancers12092379 Authors: Parker Bussies Ayi Eta Andre Pinto Sophia George Matthew Schlumbrecht Thrombocytosis (platelets ≥ 400K) is a common hematologic finding in gynecologic malignancies and associated with worse outcomes. Limited data exist on the prognostic capability of thrombocytosis in women with high-grade endometrial cancer (EC)....
Cancers, Vol. 12, Pages 2378: Skipping Exon-v6 from CD44v6-Containing Isoforms Influences Chemotherapy Response and Self-Renewal Capacity of Gastric Cancer Cells Cancers doi: 10.3390/cancers12092378 Authors: Silvana Lobo Carla Pereira Carla Oliveira Gabriela M. Almeida De novo expressed CD44 isoforms containing exon-v6 are frequently associated with gastric cancer (GC) aggressiveness, and may predict chemotherapy response in vitro. Whether exon-v6 itself is responsible for conferring...
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