Cancers, Vol. 12, Pages 2122: Effects of Cancer Stem Cells in Triple-Negative Breast Cancer and Brain Metastasis: Challenges and Solutions Cancers doi: 10.3390/cancers12082122 Authors: Kha-Liang Lee Gao Chen Tai-Yuan Chen Yung-Che Kuo Yu-Kai Su A higher propensity of developing brain metastasis exists in triple-negative breast cancer (TNBC). Upon comparing the metastatic patterns of all breast cancer subtypes, patients with TNBC exhibited increased risks of the brain being...
Fri Jul 31, 2020 03:00
Cancers, Vol. 12, Pages 2129: Single-Cell Heterogeneity of Cutaneous T-Cell Lymphomas Revealed Using RNA-Seq Technologies Cancers doi: 10.3390/cancers12082129 Authors: Karolina Rassek Katarzyna Iżykowska Cutaneous T-cell lymphomas (CTCLs) represent a large, heterogeneous group of non-Hodgkin lymphomas that primarily affect the skin. Among multiple CTCL variants, the most prevalent types are mycosis fungoides (MF) and Sézary syndrome (SS). In the past decade, the molecular...
Fri Jul 31, 2020 03:00
Cancers, Vol. 12, Pages 2120: Concurrent TP53 and CDKN2A Gene Aberrations in Newly Diagnosed Mantle Cell Lymphoma Correlate with Chemoresistance and Call for Innovative Upfront Therapy Cancers doi: 10.3390/cancers12082120 Authors: Diana Malarikova Adela Berkova Ales Obr Petra Blahovcova Michael Svaton Kristina Forsterova Eva Kriegova Eva Prihodova Lenka Pavlistova Anna Petrackova Zuzana Zemanova Marek Trneny Pavel Klener Mantle cell lymphoma (MCL)...
Fri Jul 31, 2020 03:00
Cancers, Vol. 12, Pages 2121: Histone Demethylase KDM5B as a Therapeutic Target for Cancer Therapy Cancers doi: 10.3390/cancers12082121 Authors: Anmi Jose Gautham G. Shenoy Gabriel Sunil Rodrigues Naveena A. N. Kumar Murali Munisamy Levin Thomas Jill Kolesar Ganesha Rai Praveen P. N. Rao Mahadev Rao Lysine-specific demethylase 5B (KDM5B/PLU1/JARID1B) is found to be overexpressed in numerous malignancies, including breast, lung, skin, liver, and prostate cancer....
Fri Jul 31, 2020 03:00
Cells, Vol. 9, Pages 1823: Necroptosis in Immuno-Oncology and Cancer Immunotherapy Cells doi: 10.3390/cells9081823 Authors: Jenny Sprooten Pieter De Wijngaert Isaure Vanmeerbeerk Shaun Martin Peter Vangheluwe Susan Schlenner Dmitri V. Krysko Jan B. Parys Geert Bultynck Peter Vandenabeele Abhishek D. Garg Immune-checkpoint blockers (ICBs) have revolutionized oncology and firmly established the subfield of immuno-oncology. Despite this renaissance, a subset...
Sat Aug 01, 2020 03:00
Cells, Vol. 9, Pages 1824: Probiotic Lactobacillus and Bifidobacterium Strains Counteract Adherent-Invasive Escherichia coli (AIEC) Virulence and Hamper IL-23/Th17 Axis in Ulcerative Colitis, but Not in Crohn’s Disease Cells doi: 10.3390/cells9081824 Authors: Gabriella Leccese Alessia Bibi Stefano Mazza Federica Facciotti Flavio Caprioli Paolo Landini Moira Paroni Hypersecretion of proinflammatory cytokines and dysregulated activation of the IL-23/Th17 axis in response...
Sat Aug 01, 2020 03:00
Cells, Vol. 9, Pages 1822: Repeated Application of Autologous Bone Marrow-Derived Lineage-Negative Stem/Progenitor Cells—Focus on Immunological Pathways in Patients with ALS Cells doi: 10.3390/cells9081822 Authors: Bartłomiej Baumert Anna Sobuś Monika Gołąb-Janowska Edyta Paczkowska Karolina Łuczkowska Dorota Rogińska Alicja Zawiślak Sławomir Milczarek Bogumiła Osękowska Wioletta Pawlukowska Agnieszka Meller Karolina Machowska-Sempruch Agnieszka Wełnicka...
Sat Aug 01, 2020 03:00
Cells, Vol. 9, Pages 1820: CpG-Islands as Markers for Liquid Biopsies of Cancer Patients Cells doi: 10.3390/cells9081820 Authors: Maximilian Sprang Claudia Paret Joerg Faber The analysis of tumours using biomarkers in blood is transforming cancer diagnosis and therapy. Cancers are characterised by evolving genetic alterations, making it difficult to develop reliable and broadly applicable DNA-based biomarkers for liquid biopsy. In contrast to the variability in gene mutations,...
Sat Aug 01, 2020 03:00
Cells, Vol. 9, Pages 1821: mtDNA Mutation Accumulation in Muscle Is Not a Major Cause of Fiber Loss. Reply to “Comment on: Mitochondrial Mechanisms of Neuromuscular Junction Degeneration with Aging. Cells 2020, 9, 197” Cells doi: 10.3390/cells9081821 Authors: Russell T. Hepple I thank you for your comment on our review paper [...]
Sat Aug 01, 2020 03:00
Cells, Vol. 9, Pages 1819: Cholesterol and Mevalonate: Two Metabolites Involved in Breast Cancer Progression and Drug Resistance through the ERRα Pathway Cells doi: 10.3390/cells9081819 Authors: Matteo Brindisi Marco Fiorillo Luca Frattaruolo Federica Sotgia Michael P. Lisanti Anna Rita Cappello Breast cancer is the second greatest cause of cancer-related death in women. Resistance to endocrine treatments or chemotherapy is a limiting drawback. In this context, this work...
Fri Jul 31, 2020 03:00
Cells, Vol. 9, Pages 1816: Alveolar Type II Cells or Mesenchymal Stem Cells: Comparison of Two Different Cell Therapies for the Treatment of Acute Lung Injury in Rats Cells doi: 10.3390/cells9081816 Authors: Raquel Guillamat-Prats Marta Camprubí-Rimblas Ferranda Puig Raquel Herrero Neus Tantinyà Anna Serrano-Mollar Antonio Artigas The use of cell therapies has recently increased for the treatment of pulmonary diseases. Mesenchymal stem/stromal cells (MSCs) and alveolar...
Fri Jul 31, 2020 03:00
Cells, Vol. 9, Pages 1818: Depression-Associated Gene Negr1-Fgfr2 Pathway Is Altered by Antidepressant Treatment Cells doi: 10.3390/cells9081818 Authors: Lucia Carboni Francesca Pischedda Giovanni Piccoli Mario Lauria Laura Musazzi Maurizio Popoli Aleksander A. Mathé Enrico Domenici The Negr1 gene has been significantly associated with major depression in genetic studies. Negr1 encodes for a cell adhesion molecule cleaved by the protease Adam10, thus activating Fgfr2...
Fri Jul 31, 2020 03:00
Cells, Vol. 9, Pages 1817: Cyclopamine and Rapamycin Synergistically Inhibit mTOR Signalling in Mouse Hepatocytes, Revealing an Interaction of Hedgehog and mTor Signalling in the Liver Cells doi: 10.3390/cells9081817 Authors: Luise Spormann Christiane Rennert Erik Kolbe Fritzi Ott Carolin Lossius Robert Lehmann Rolf Gebhardt Thomas Berg Madlen Matz-Soja In the liver, energy homeostasis is mainly regulated by mechanistic target of rapamycin (mTOR) signalling, which...
Fri Jul 31, 2020 03:00
Cells, Vol. 9, Pages 1815: The Secret Garden of Neuronal circRNAs Cells doi: 10.3390/cells9081815 Authors: Silvia Gasparini Valerio Licursi Carlo Presutti Cecilia Mannironi High-throughput transcriptomic profiling approaches have revealed that circular RNAs (circRNAs) are important transcriptional gene products, identified across a broad range of organisms throughout the eukaryotic tree of life. In the nervous system, they are particularly abundant, developmentally regulated,...
Fri Jul 31, 2020 03:00
Challenges, Vol. 11, Pages 16: Dozy-Chaos Mechanics for a Broad Audience Challenges doi: 10.3390/challe11020016 Authors: Vladimir V. Egorov A new and universal theoretical approach to the dynamics of the transient state in elementary physico-chemical processes, called dozy-chaos mechanics (Egorov, V.V. Heliyon Physics2019, 5, e02579), is introduced to a wide general readership.
Fri Jul 31, 2020 03:00
Chemosensors, Vol. 8, Pages 61: Phage-Based Sensors in Medicine: A Review Chemosensors doi: 10.3390/chemosensors8030061 Authors: Sebastian J. Machera Joanna Niedziółka-Jӧnsson Katarzyna Szot-Karpińska Bacteriophages are interesting entities on the border of biology and chemistry. In nature, they are bacteria parasites, while, after genetic manipulation, they gain new properties, e.g., selectively binding proteins. Owing to this, they may be applied as recognition elements in biosensors....
Fri Jul 31, 2020 03:00
Chemosensors, Vol. 8, Pages 60: Opto-Electronic Nose Coupled to a Silicon Micro Pre-Concentrator Device for Selective Sensing of Flavored Waters Chemosensors doi: 10.3390/chemosensors8030060 Authors: Sami Slimani Etienne Bultel Thomas Cubizolle Cyril Herrier Tristan Rousselle Thierry Livache Headspace analysis of highly humid samples remains a challenge for artificial olfaction. Based on surface plasmon resonance imaging and bio-based sensors, the NeOse Pro olfactive analyzer...
Fri Jul 31, 2020 03:00
Children, Vol. 7, Pages 86: Defining a “Good Death” in Pediatric Oncology: A Mixed Methods Study of Healthcare Providers Children doi: 10.3390/children7080086 Authors: Mallory R. Taylor Krysta S. Barton Jenny M. Kingsley Julia Heunis Abby R. Rosenberg Delivering optimal end-of-life (EOL) care to children and adolescents is a healthcare priority, yet relatively little is known about what patients, families, and healthcare providers (HCPs) consider “best”...
Fri Jul 31, 2020 03:00
Children, Vol. 7, Pages 85: Effect of Functional Progressive Resistance Exercise on Lower Extremity Structure, Muscle Tone, Dynamic Balance and Functional Ability in Children with Spastic Cerebral Palsy Children doi: 10.3390/children7080085 Authors: Hye-Jin Cho Byoung-Hee Lee The purpose of this study was to investigate the effects of functional progressive resistance exercise (FPRE) on muscle tone, dynamic balance and functional ability in children with spastic cerebral palsy. Twenty-five...
Fri Jul 31, 2020 03:00
Cosmetics, Vol. 7, Pages 62: Pickering Emulsions Stabilized by Calcium Carbonate Particles: A New Topical Formulation Cosmetics doi: 10.3390/cosmetics7030062 Authors: Joana Marto Andreia Nunes Ana Margarida Martins João Carvalheira Pedro Prazeres Lídia Gonçalves Alexandre Marques António Lucas Helena Margarida Ribeiro Pickering emulsions are systems composed of two immiscible fluids stabilized by solid organic or inorganic particles. Pickering emulsions are particularly...
Fri Jul 31, 2020 03:00
Dentistry Journal, Vol. 8, Pages 79: Comparative Evaluation of Digitization of Diagnostic Dental Cast (Plaster) Models Using Different Scanning Technologies Dentistry Journal doi: 10.3390/dj8030079 Authors: Aalaa Emara Neha Sharma Florian S. Halbeisen Bilal Msallem Florian M. Thieringer Rapidly developing digital dental technologies have substantially simplified the documentation of plaster dental models. The large variety of available scanners with varying degrees of accuracy...
Sun Aug 02, 2020 03:00
Diagnostics, Vol. 10, Pages 552: Radiographic Analysis on the Distortion of the Anatomy of First Metatarsal Head in Dorsoplantar Projection Diagnostics doi: 10.3390/diagnostics10080552 Authors: Jessica Grande-del-Arco Ricardo Becerro-de-Bengoa-Vallejo Patricia Palomo-López Daniel López-López César Calvo-Lobo Eduardo Pérez-Boal Marta Elena Losa-Iglesias Carlos Martin-Villa David Rodriguez-Sanz Background: The diagnostic of flat and crest-shaped of first metatarsal...
Sun Aug 02, 2020 03:00
Diagnostics, Vol. 10, Pages 551: Machine Learning Model Comparison in the Screening of Cholangiocarcinoma Using Plasma Bile Acids Profiles Diagnostics doi: 10.3390/diagnostics10080551 Authors: Davide Negrini Patrick Zecchin Andrea Ruzzenente Fabio Bagante Simone De Nitto Matteo Gelati Gian Luca Salvagno Elisa Danese Giuseppe Lippi Bile acids (BAs) assessments are garnering increasing interest for their potential involvement in development and progression of cholangiocarcinoma...
Sun Aug 02, 2020 03:00
Diagnostics, Vol. 10, Pages 550: Personalized Treatment Selection and Disease Monitoring Using Circulating Tumor DNA Profiling in Real-World Cancer Patient Management Diagnostics doi: 10.3390/diagnostics10080550 Authors: Julius Wehrle Ulrike Philipp Martina Jolic Marie Follo Saskia Hussung Silvia Waldeck Max Deuter Michael Rassner Jan Braune Justyna Rawluk Christine Greil Cornelius F. Waller Heiko Becker Jesús Duque-Afonso Anna-L. Illert Ralph M....
Sun Aug 02, 2020 03:00
Diagnostics, Vol. 10, Pages 548: Effect of Coronavirus Disease 2019 in Pulmonary Circulation. The Particular Scenario of Precapillary Pulmonary Hypertension Diagnostics doi: 10.3390/diagnostics10080548 Authors: Jorge Nuche Teresa Segura de la Segura de la Cal Carmen Jiménez López Jiménez López Guarch Francisco López-Medrano Carmen Pérez-Olivares Pérez-Olivares Delgado Fernando Arribas Arribas Ynsaurriaga Juan F. Delgado Borja Ibáñez Eduardo Oliver Pilar Escribano...
Fri Jul 31, 2020 03:00
Diagnostics, Vol. 10, Pages 549: An Update on the Prognostic and Predictive Serum Biomarkers in Metastatic Prostate Cancer Diagnostics doi: 10.3390/diagnostics10080549 Authors: Helen Saxby Christos Mikropoulos Stergios Boussios Serum biomarkers are molecules produced by normal and abnormal cells. Prostate specific antigen (PSA) is an example of a serum biomarker used widely in the diagnosis and prognostication of prostate cancer. PSA has its limitations as it is organ- but not...
Fri Jul 31, 2020 03:00
Diagnostics, Vol. 10, Pages 547: Selected Matrix Metalloproteinases (MMP-2, MMP-7) and Their Inhibitor (TIMP-2) in Adult and Pediatric Cancer Diagnostics doi: 10.3390/diagnostics10080547 Authors: Kaczorowska Miękus Stefanowicz Adamkiewicz-Drożyńska The tumor microenvironment (TME) consists of numerous biologically relevant elements. One of the most important components of the TME is the extracellular matrix (ECM). The compounds of the ECM create a network that provides structural...
Fri Jul 31, 2020 03:00
Diversity, Vol. 12, Pages 301: Diversity of Tree Species in Gap Regeneration under Tropical Moist Semi-Deciduous Forest: An Example from Bia Tano Forest Reserve Diversity doi: 10.3390/d12080301 Authors: Maame Esi Hammond Radek Pokorný In a quest to improve the diversity and conservation of native tree species in tropical African forests, gap regeneration remains all-important nature-promoting silviculture practice and ecosystem-based strategy for attaining these ecological goals....
Sat Aug 01, 2020 03:00
Diversity, Vol. 12, Pages 300: Structure and Biodiversity of Rhodolith Seabeds: A Special Issue Diversity doi: 10.3390/d12080300 Authors: Fernando Tuya Rhodolith seabeds function as ‘ecosystems engineers’, which globally provide a range of ‘ecosystem services’. However, knowledge on the structure, composition and distribution of rhodolith seabeds is still lacking. This Special Issue comprises six articles, addressing specific questions of rhodolith...
Sat Aug 01, 2020 03:00
Environments, Vol. 7, Pages 58: Multi-Scale Modeling and Study of Aerosol Growth in an Amine-based CO2 Capture Absorber Environments doi: 10.3390/environments7080058 Authors: Jia-Lin Kang Kuan-Ting Liu David Shan-Hill Wong Shi-Shang Jang De-Hao Tsai A monoethanolamine (MEA) aerosol growth model was developed to quantify the aerosol growth factor in an amine-based CO2 capture absorber that considers the gas-liquid interactions, and it is empirically validated by measuring...
Fri Jul 31, 2020 03:00
Environments, Vol. 7, Pages 57: Fire as a Selection Agent for the Dissemination of Invasive Species: Case Study on the Evolution of Forest Coverage Environments doi: 10.3390/environments7080057 Authors: Leonel J. R. Nunes Mauro A. M. Raposo Catarina I. R. Meireles Carlos J. Pinto Gomes Nuno M. C. Almeida Ribeiro Climate change has enhanced the occurrence of rural fires, since changes in the hydrological cycle have led to the occurrence of increasingly long and frequent periods...
Fri Jul 31, 2020 03:00
Fermentation, Vol. 6, Pages 78: Comparison of the Glycolytic and Alcoholic Fermentation Pathways of Hanseniaspora vineae with Saccharomyces cerevisiae Wine Yeasts Fermentation doi: 10.3390/fermentation6030078 Authors: Valera Boido Dellacassa Carrau Hanseniaspora species can be isolated from grapes and grape musts, but after the initiation of spontaneous fermentation, they are displaced by Saccharomyces cerevisiae. Hanseniaspora vineae is particularly valuable since this...
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Foods, Vol. 9, Pages 1042: Osmodehydrofreezing: An Integrated Process for Food Preservation during Frozen Storage Foods doi: 10.3390/foods9081042 Authors: Maria C. Giannakourou Efimia K. Dermesonlouoglou Petros S. Taoukis Osmodehydrofreezing (ODF), a combined preservation process where osmotic dehydration is applied prior to freezing, achieves several advantages, especially in plant tissues, sensitive to freezing. OD pre-treatment can lead to the selective impregnation of solutes...
Sun Aug 02, 2020 03:00
Foods, Vol. 9, Pages 1040: 13C NMR-Based Chemical Fingerprint for the Varietal and Geographical Discrimination of Wines Foods doi: 10.3390/foods9081040 Authors: Alberto Mannu Ioannis K. Karabagias Maria Enrica Di Pietro Salvatore Baldino Vassilios K. Karabagias Anastasia V. Badeka A fast, economic, and eco-friendly methodology for the wine variety and geographical origin differentiation using 13C nuclear magnetic resonance (NMR) data in combination with machine learning...
Sun Aug 02, 2020 03:00
Foods, Vol. 9, Pages 1041: Comparison of Thermal and High-Pressure Gelation of Potato Protein Isolates Foods doi: 10.3390/foods9081041 Authors: Hadas Katzav Libi Chirug Zoya Okun Maya Davidovich-Pinhas Avi Shpigelman Potato protein isolate (PPI), a commercial by-product of the starch industry, is a promising novel protein for food applications with limited information regarding its techno-functionality. This research focused on the formation of both thermal and high-pressure...
Sun Aug 02, 2020 03:00
Foods, Vol. 9, Pages 1039: Antioxidant and Anti-Inflammatory Activities of Safflower (Carthamus tinctorius L.) Honey Extract Foods doi: 10.3390/foods9081039 Authors: Li-Ping Sun Feng-Feng Shi Wen-Wen Zhang Zhi-Hao Zhang Kai Wang Safflower honey is a unique type of monofloral honey collected from the nectar of Carthamus tinctorius L. in the Apis mellifera colonies of northwestern China. Scant information is available regarding its chemical composition and biological activities....
Sun Aug 02, 2020 03:00
Foods, Vol. 9, Pages 1038: Estimation of Dietary Exposure to Contaminants Transferred from the Packaging in Fatty Dry Foods Based on Cereals Foods doi: 10.3390/foods9081038 Authors: Antía Lestido-Cardama Ana Rodríguez Bernaldo de Quirós Juana Bustos M. Luisa Lomo Perfecto Paseiro Losada Raquel Sendón Food packaging has received special attention from the food safety standpoint since it could be a potential source of contamination through the migration of chemical substances...
Sat Aug 01, 2020 03:00
Foods, Vol. 9, Pages 1036: Food and COVID-19: Preventive/Co-therapeutic Strategies Explored by Current Clinical Trials and in Silico Studies Foods doi: 10.3390/foods9081036 Authors: Giacomo Di Matteo Mattia Spano Michela Grosso Andrea Salvo Cinzia Ingallina Mariateresa Russo Alberto Ritieni Luisa Mannina Foods, food ingredients, and their balanced consumption are recognized to have an important role in achieving or maintaining a state of wellbeing by acting as carriers...
Sat Aug 01, 2020 03:00
Foods, Vol. 9, Pages 1035: Nutritional Features and Bread-Making Performance of Wholewheat: Does the Milling System Matter? Foods doi: 10.3390/foods9081035 Authors: Maria Ambrogina Pagani Debora Giordano Gaetano Cardone Antonella Pasqualone Maria Cristina Casiraghi Daniela Erba Massimo Blandino Alessandra Marti Despite the interest in stone-milling, there is no information on the potential advantages of using the resultant wholegrain flour (WF) in bread-making. Consequently,...
Sat Aug 01, 2020 03:00
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