Antibiotics, Vol. 9, Pages 523: Rapid Antibacterial Activity of Cannabichromenic Acid against Methicillin-Resistant Staphylococcus aureus Antibiotics doi: 10.3390/antibiotics9080523 Authors: Maria Galletta Tristan A. Reekie Gayathri Nagalingam Amy L. Bottomley Elizabeth J. Harry Michael Kassiou James A. Triccas Methicillin-resistant Staphylococcus aureus (MRSA) has proven to be an imminent threat to public health, intensifying the need for novel therapeutics. Previous...
Antibiotics, Vol. 9, Pages 522: Lactoferrin Functionalized Biomaterials: Tools for Prevention of Implant-Associated Infections Antibiotics doi: 10.3390/antibiotics9080522 Authors: Emoke Pall Alexandra Roman Tissue engineering is one of the most important biotechnologies in the biomedical field. It requires the application of the principles of scientific engineering in order to design and build natural or synthetic biomaterials feasible for the maintenance of tissues and organs. Depending...
Antibiotics, Vol. 9, Pages 521: Effectiveness of Electronic Guidelines (GERH®) to Improve the Clinical Use of Antibiotics in an Intensive Care Unit Antibiotics doi: 10.3390/antibiotics9080521 Authors: Navarro-Gomez Gutierrez-Fernandez Rodriguez-Maresca Olvera-Porcel Sorlozano-Puerto :The objective of the study was to evaluate the capacity of GERH®-derived local resistance maps (LRMs) to predict antibiotic susceptibility profiles and recommend the appropriate...
Antibiotics, Vol. 9, Pages 520: Strain-Specific Adaptations of Streptococcus mitis-oralis to Serial In Vitro Passage in Daptomycin (DAP): Genotypic and Phenotypic Characteristics Antibiotics doi: 10.3390/antibiotics9080520 Authors: Nagendra N. Mishra Truc T. Tran Cesar A. Arias Ravin Seepersaud Paul M. Sullam Arnold S. Bayer Viridans group streptococci (VGS), especially the Streptococcus mitis-oralis subgroup, are pivotal pathogens in a variety of invasive endovascular...
Antibiotics, Vol. 9, Pages 519: Enzybiotics LYSSTAPH-S and LYSDERM-S as Potential Therapeutic Agents for Chronic MRSA Wound Infections Antibiotics doi: 10.3390/antibiotics9080519 Authors: Lukáš Vacek Šárka Kobzová Richard Čmelík Roman Pantůček Lubomír Janda Antibacterial antibiotic therapy has played an important role in the treatment of bacterial infections for almost a century. The increasing resistance of pathogenic bacteria to antibiotics leads to an attempt to use previously...
Antibiotics, Vol. 9, Pages 518: Chemical Profiling and Discrimination of Essential Oils from Six Ferula Species Using GC Analyses Coupled with Chemometrics and Evaluation of Their Antioxidant and Enzyme Inhibitory Potential Antibiotics doi: 10.3390/antibiotics9080518 Authors: Fadia S. Youssef Munira A. Mamatkhanova Nilufar Z. Mamadalieva Gokhan Zengin Salima F. Aripova Elham Alshammari Mohamed L. Ashour The differences in the composition of essential oils obtained from...
Antibiotics, Vol. 9, Pages 517: Melittin from Apis florea Venom as a Promising Anticancer Agent Antibiotics doi: 10.3390/antibiotics9080517 Authors: Sirikwan Sangboonruang Kuntida Kitidee Panuwan Chantawannakul Khajornsak Tragoolpua Yingmanee Tragoolpua Melittin, a major component found in bee venom, is produced by the Apis species of the honey bee. In this study, the effect of melittin derived from Apis florea (Mel-AF), which is a wild honey bee species that is indigenous...
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Antibodies, Vol. 9, Pages 42: The Course of SARS-COV2 Infection Was Not Severe in a Crohn’s Patient Who Administered Maintenance Anti-TNF Therapy Overlapping the Early Pre-Symptomatic Period of Infection Antibodies doi: 10.3390/antib9030042 Authors: Francis Okeke Anjali Mone Arun Swaminath The Inflammatory Bowel Disease (IBD) population, which may require treatment with immunosuppressive medications, may be uniquely vulnerable to COVID-19 infection. In fact, there is some evidence...
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Antioxidants, Vol. 9, Pages 759: Oxidative Stress and Pro-Inflammatory Status in Patients with Non-Alcoholic Fatty Liver Disease Antioxidants doi: 10.3390/antiox9080759 Authors: Margalida Monserrat-Mesquida Magdalena Quetglas-Llabrés Manuela Abbate Sofía Montemayor Catalina M. Mascaró Miguel Casares Silvia Tejada Itziar Abete Maria Angeles Zulet Josep A. Tur J. Alfredo Martínez Antoni Sureda Background: Nonalcoholic fatty liver disease (NAFLD) is characterized...
Antioxidants, Vol. 9, Pages 758: Iron Overload, Oxidative Stress and Calcium Mishandling in Cardiomyocytes: Role of the Mitochondrial Permeability Transition Pore Antioxidants doi: 10.3390/antiox9080758 Authors: Richard Gordan Nadezhda Fefelova Judith K. Gwathmey Lai-Hua Xie Iron (Fe) plays an essential role in many physiological processes. Hereditary hemochromatosis or frequent blood transfusions often cause iron overload (IO), which can lead to cardiomyopathy and arrhythmias;...
Antioxidants, Vol. 9, Pages 757: Engineering the Unicellular Alga Phaeodactylum tricornutum for Enhancing Carotenoid Production Antioxidants doi: 10.3390/antiox9080757 Authors: Francesco Manfellotto Giulio Rocco Stella Angela Falciatore Christophe Brunet Maria Immacolata Ferrante Microalgae represent a promising resource for the production of beneficial natural compounds due to their richness in secondary metabolites and easy cultivation. Carotenoids feature among distinctive...
Antioxidants, Vol. 9, Pages 755: Advanced Glycation End Product Accumulation in Subjects with Open-Angle Glaucoma with and without Exfoliation Antioxidants doi: 10.3390/antiox9080755 Authors: Tomoki Shirakami Mikihiro Yamanaka Jo Fujihara Yotaro Matsuoka Yuko Gohto Akira Obana Masaki Tanito Advanced glycation end products (AGEs), which are the products of a non-enzymatic reaction between reducing sugars and other macromolecules, are critical in aging, as well as metabolic...
Antioxidants, Vol. 9, Pages 756: Theoretical Study of the Iron Complexes with Aminoguanidine: Investigating Secondary Antioxidant Activity Antioxidants doi: 10.3390/antiox9080756 Authors: Guillermo García-Díez Nelaine Mora-Diez A thorough analysis of the thermodynamic stability of various complexes of aminoguanidine (AG) with Fe(III) at a physiological pH is presented. Moreover, the secondary antioxidant activity of AG is studied with respect to its kinetic role in the Fe(III) reduction...
Antioxidants, Vol. 9, Pages 753: Syk Kinase Inhibitors Synergize with Artemisinins by Enhancing Oxidative Stress in Plasmodium Falciparum-Parasitized Erythrocytes Antioxidants doi: 10.3390/antiox9080753 Authors: Ioannis Tsamesidis Karine Reybier Giuseppe Marchetti Maria Carmina Pau Patrizia Virdis Claudio Fozza Francoise Nepveu Philip S. Low Francesco Michelangelo Turrini Antonella Pantaleo Although artemisinin-based combination therapies (ACTs) treat Plasmodium...
Antioxidants, Vol. 9, Pages 754: Antioxidant Effects of PS5, a Peptidomimetic of Suppressor of Cytokine Signaling 1, in Experimental Atherosclerosis Antioxidants doi: 10.3390/antiox9080754 Authors: Sara La Manna Laura Lopez-Sanz Susana Bernal Luna Jimenez-Castilla Ignacio Prieto Giancarlo Morelli Carmen Gomez-Guerrero Daniela Marasco The chronic activation of the Janus kinase/signal transducer and activator of the transcription (JAK/STAT) pathway is linked to oxidative...
Antioxidants, Vol. 9, Pages 752: Chronic Kidney Disease as Oxidative Stress- and Inflammatory-Mediated Cardiovascular Disease Antioxidants doi: 10.3390/antiox9080752 Authors: Alina Podkowińska Dorota Formanowicz Generating reactive oxygen species (ROS) is necessary for both physiology and pathology. An imbalance between endogenous oxidants and antioxidants causes oxidative stress, contributing to vascular dysfunction. The ROS-induced activation of transcription factors and proinflammatory...
Antioxidants, Vol. 9, Pages 750: Mitochondrial Activation and Reactive Oxygen-Species Overproduction during Sperm Capacitation are Independent of Glucose Stimuli Antioxidants doi: 10.3390/antiox9080750 Authors: David F. Carrageta Bárbara Guerra-Carvalho Mário Sousa Alberto Barros Pedro F. Oliveira Mariana P. Monteiro Marco G. Alves Spermatozoa capacitation is a complex process that requires specific ionic and energetic conditions to support biochemical alterations leading...
Antioxidants, Vol. 9, Pages 751: The KEAP1/NRF2 Signaling Pathway in Keratinization Antioxidants doi: 10.3390/antiox9080751 Authors: Yosuke Ishitsuka Tatsuya Ogawa Dennis Roop Keratinization is a tissue adaptation, but aberrant keratinization is associated with skin disorders such as ichthyoses, atopic dermatitis, psoriasis, and acne. The disease phenotype stems from the interaction between genes and the environment; therefore, an understanding of the adaptation machinery may lead...
Antioxidants, Vol. 9, Pages 749: Toxicological Profile of the Pain-Relieving Antioxidant Compound Thioctic Acid in Its Racemic and Enantiomeric Forms Antioxidants doi: 10.3390/antiox9080749 Authors: Elena Lucarini Elena Trallori Daniele Tomassoni Francesco Amenta Carla Ghelardini Alessandra Pacini Lorenzo Di Cesare Mannelli Thioctic acid is a multipotent antioxidant compound existing as dextrorotatory (+), eutomer and naturally occurring and levorotatory (−)....
Antioxidants, Vol. 9, Pages 748: The Interaction of the Endogenous Hydrogen Sulfide and Oxytocin Systems in Fluid Regulation and the Cardiovascular System Antioxidants doi: 10.3390/antiox9080748 Authors: Nicole Denoix Oscar McCook Sarah Ecker Rui Wang Christiane Waller Peter Radermacher Tamara Merz The purpose of this review is to explore the parallel roles and interaction of hydrogen sulfide (H2S) and oxytocin (OT) in cardiovascular regulation and fluid homeostasis....
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Arts, Vol. 9, Pages 90: Between Heaven and Earth: Places of Worship in Egypt and Syria through the Mirror of Visual Evidence Arts doi: 10.3390/arts9030090 Authors: Rachel Sarfati In the villages Dammūh, near Fustֿׅatׅ, and Jobar, near Damascus, there were places of worship dedicated to Moses and Elijah which were part of central pilgrimage sites. This article will propose a depiction of the architecture and interiors of these places based on visual and literary sources from the Middle...
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Atmosphere, Vol. 11, Pages 869: A Hydrodynamical Atmosphere/Ocean Coupled Modeling System for Multiple Tropical Cyclones Atmosphere doi: 10.3390/atmos11080869 Authors: Ghassan J. Alaka Dmitry Sheinin Biju Thomas Lew Gramer Zhan Zhang Bin Liu Hyun-Sook Kim Avichal Mehra The goal of this paper is to introduce a new multi-storm atmosphere/ocean coupling scheme that was implemented and tested in the Basin-Scale Hurricane Weather Research and Forecasting (HWRF-B) model....
Atmosphere, Vol. 11, Pages 868: Health Effects of Air-Quality Regulations in Seoul Metropolitan Area: Applying Synthetic Control Method to Controlled-Interrupted Time-Series Analysis Atmosphere doi: 10.3390/atmos11080868 Authors: Soo-Yeon Kim Hyomi Kim Jong-Tae Lee Despite enormous investment in air-quality regulations, there are only a few studies about the health effects of the air-quality regulations. By applying synthetic control methods to controlled-interrupted time-series...
Atmosphere, Vol. 11, Pages 867: Quantifying the Changing Nature of the Winter Season Precipitation Phase from 1849 to 2017 in Downtown Toronto (Canada) Atmosphere doi: 10.3390/atmos11080867 Authors: Micah J. Hewer William A. Gough One hundred and sixty–nine years of weather station data were analyzed to quantify the changing nature of the winter season precipitation phase in the downtown area of Toronto (Canada). The precipitation variables examined were rainfall, snowfall...
Atmosphere, Vol. 11, Pages 866: An Improved Method for Optical Characterization of Mineral Dust and Soot Particles in the El Paso-Juárez Airshed Atmosphere doi: 10.3390/atmos11080866 Authors: Javier Polanco Manuel Ramos Rosa M. Fitzgerald William R. Stockwell Highly time-resolved aerosol measurements and analysis are necessary for a proper aerosol characterization in many polluted regions, because aerosol concentrations in polluted environments can change over time scales of...
Atmosphere, Vol. 11, Pages 864: Operational Response to Volcanic Ash Risks Using HOTVOLC Satellite-Based System and MOCAGE-Accident Model at the Toulouse VAAC Atmosphere doi: 10.3390/atmos11080864 Authors: Mathieu Gouhier Mathieu Deslandes Yannick Guéhenneux Philippe Hereil Philippe Cacault Béatrice Josse In 2010, the Eyjafjallajökull volcano erupted, generating an ash cloud causing unprecedented disruption of European airspace. Despite an exceptional situation,...
Atmosphere, Vol. 11, Pages 865: Why Does Fog Deepen? An Analytical Perspective Atmosphere doi: 10.3390/atmos11080865 Authors: Jonathan G. Izett Bas J. H. van de Wiel The overall depth of a fog layer is one of the important factors in determining the hazard that a fog event presents. With discrete observations and often coarse numerical grids, however, fog depth cannot always be accurately determined. To address this, we derive a simple analytical relation that describes the change...
Atmosphere, Vol. 11, Pages 863: Modeling Emissions from Concentrated Sources into Large-Scale Models: Theory and apriori Testing Atmosphere doi: 10.3390/atmos11080863 Authors: Roberto Paoli This paper presents a general procedure to incorporate the effects emissions from localized sources, such as aircraft or ship engines, into chemical transport models (CTM). In this procedure, the species concentrations in each grid box of a CTM are split into plume or small-scale concentrations and...
Atmosphere, Vol. 11, Pages 862: Analysis of Cooling and Humidification Effects of Different Coverage Types in Small Green Spaces (SGS) in the Context of Urban Homogenization: A Case of HAU Campus Green Spaces in Summer in Zhengzhou, China Atmosphere doi: 10.3390/atmos11080862 Authors: Huawei Li Handong Meng Ruizhen He Yakai Lei Yuchen Guo Amoako-atta Ernest Sandor Jombach Guohang Tian In the context of global warming, more and more cities are experiencing extreme...
Atmosphere, Vol. 11, Pages 860: Affective Normative Data for English Weather Words Atmosphere doi: 10.3390/atmos11080860 Authors: Alan E. Stewart The research in this article examines the emotional associations people have to common weather words and to selected terms that appear in weather communications (e.g., severe thunderstorm warning). A sample of 420 university students provided ratings for each term along four dimensions: 1. Valence (unhappy vs. happy), 2. Arousal (calm vs. excited),...
Atmosphere, Vol. 11, Pages 861: Isomass and Probability Maps of Ash Fallout Due to Vulcanian Eruptions at Tungurahua Volcano (Ecuador) Deduced from Historical Forecasting Atmosphere doi: 10.3390/atmos11080861 Authors: René Parra Eliana Cadena Joselyne Paz Diana Medina Since April of 2015, the ash dispersion and ash fallout due to Vulcanian eruptions at Tungurahua, one of the most active volcanoes in Ecuador, have been forecasted daily. For this purpose, our forecasting system...
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Beverages, Vol. 6, Pages 51: Functional Beer—A Review on Possibilities Beverages doi: 10.3390/beverages6030051 Authors: Kristina Habschied Antonio Živković Vinko Krstanović Krešimir Mastanjević The expansion of the beer industry has enabled many possibilities for improvement regarding the taste, aroma and functionality of this drink. Health-related issues and a general wish for healthier lifestyles has resulted in increased demand for functional beers. The addition of different...
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Biology, Vol. 9, Pages 229: The Dawn of the Age of Multi-Parent MAGIC Populations in Plant Breeding: Novel Powerful Next-Generation Resources for Genetic Analysis and Selection of Recombinant Elite Material Biology doi: 10.3390/biology9080229 Authors: Andrea Arrones Santiago Vilanova Mariola Plazas Giulio Mangino Laura Pascual María José Díez Jaime Prohens Pietro Gramazio The compelling need to increase global agricultural production requires new breeding approaches...
Biology, Vol. 9, Pages 228: Protoplast Isolation and Shoot Regeneration from Protoplast-Derived Callus of Petunia hybrida Cv. Mirage Rose Biology doi: 10.3390/biology9080228 Authors: Hyun Hee Kang Aung Htay Naing Chang Kil Kim Despite the increasing use of protoplasts in plant biotechnology research, shoot regeneration from protoplasts remains challenging. In this study, we investigated the factors involved in protoplast isolation, callus induction, and shoot regeneration in Petunia...
Biology, Vol. 9, Pages 226: Inverted Covariate Effects for First versus Mutated Second Wave Covid-19: High Temperature Spread Biased for Young Biology doi: 10.3390/biology9080226 Authors: Hervé Seligmann Siham Iggui Mustapha Rachdi Nicolas Vuillerme Jacques Demongeot (1) Background: Here, we characterize COVID-19’s waves, following a study presenting negative associations between first wave COVID-19 spread parameters and temperature. (2) Methods: Visual examinations...
Biology, Vol. 9, Pages 227: Noninvasive and Safe Cell Viability Assay for Breast Cancer MCF-7 Cells Using Natural Food Pigment Biology doi: 10.3390/biology9080227 Authors: Kyohei Yamashita Ryoma Tagawa Yoshikazu Higami Eiji Tokunaga A dye exclusion test (DET) was performed to determine the viability of human breast cancer cells MCF-7, using natural food pigments as compared with trypan blue (TB), a typical synthetic dye for DET known to exhibit teratogenicity and cytotoxicity....
Biology, Vol. 9, Pages 224: Influence of Bone Definition and Finite Element Parameters in Bone and Dental Implants Stress: A Literature Review Biology doi: 10.3390/biology9080224 Authors: María Prados-Privado Carlos Martínez-Martínez Sergio A. Gehrke Juan Carlos Prados-Frutos Bone plays an important role in dental implant treatment success. The goal of this literature review is to analyze the influence of bone definition and finite element parameters on stress in dental implants...
Biology, Vol. 9, Pages 225: Properties of Arabinogalactan Proteins (AGPs) in Apple (Malus × Domestica) Fruit at Different Stages of Ripening Biology doi: 10.3390/biology9080225 Authors: Agata Leszczuk Justyna Cybulska Tomasz Skrzypek Artur Zdunek Arabinogalactan proteins (AGPs) are constituents of the cell wall–plasma membrane continuum in fruit tissue. The aim of the study was to characterise AGPs contained in fruit by determination of their chemical structure and...
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Biomedicines, Vol. 8, Pages 289: R-α-Lipoic Acid and 4-Phenylbutyric Acid Have Distinct Hypolipidemic Mechanisms in Hepatic Cells Biomedicines doi: 10.3390/biomedicines8080289 Authors: Bo He Régis Moreau The constitutive activation of the mechanistic target of rapamycin complex 1 (mTORC1) leads to the overproduction of apoB-containing triacylglycerol-rich lipoproteins in HepG2 cells. R-α-lipoic acid (LA) and 4-phenylbutyric acid (PBA) have hypolipidemic function but their...
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