Abstract Many studies in the rigid gas permeable (RGP) lens fitting field have focused on providing the best fit for patients with irregular astigmatism, a challenging issue. Despite the ease and accuracy of fitting in the current fitting methods, no studies have provided a high-pace solution with the final best fit to assist experts. This work presents a deep learning solution for identifying features in Pentacam four refractive maps and RGP base curve identification. An authentic...
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An 8-year-old female of Italian (paternal) and Irish (maternal) descent was evaluated for recurrent fevers that started at about 2 months of age. The fevers would cycle about every 8 weeks and lasted 3-4 days, with temperatures as high as 103o F. Associated symptoms included pharyngitis and abdominal pain, but no rashes. More recently, fevers had been occurring weekly and had been associated with more severe abdominal pain. These febrile episodes were occurring in addition to reported recurrent and...
Chronic urticaria (CU) is a common skin disorder that is characterized by the occurrence of wheals, angioedema, or both for more than six weeks. It is further divided into: chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU).1 To date, the humanized anti-IgE monoclonal antibody omalizumab has become well recognized as an effective and well-tolerated therapy for CU patients who remain symptomatic on H1-antihistamines.
Tiotropium, a long-acting form of anticholinergic bronchodilator, has been indicated for the treatment of chronic obstructive pulmonary disease for over 10 years, followed by its more recent approval for use in patients with asthma. In 2014, tiotropium administered through Respimat® Soft Mist inhaler (Boehringer Ingelheim, Ingelheim am Rhein, Germany), was indicated as the first long-acting muscarinic antagonists (LAMA) approved for asthma maintenance therapy. A systematic review and meta-analysis...
Treatment of asthma and its complications results in a significant burden to the healthcare system. In 2015, approximately 25 million Americans were reported to have asthma.1 In 2014 in the United States, asthma was associated with 3,651 deaths, 439,000 hospitalizations, 2.1 million emergency room (ER) visits, and more than 11 million outpatient/office visits.1 Studies report a wide range of patients with uncontrolled asthma (17-34%)2-4 and with severe asthma (5 to 20%).4-6 The small percentage of...
Although previous studies have reported an important role of IL - 13 and its genetic polymorphisms in atopic dermatitis (AD), many of these prior reports focused on the missense variant rs20541 (Gln144Arg) without fine mapping of the gene region.
Asthma is characterized by chronic airway inflammation, and inhaled corticosteroids (ICSs) have been recommended as first-line treatment. However, response to ICS treatment is various, and the prediction of response to ICS is still difficult, especially in individuals with newly diagnosed asthma.
Mastocytosis is characterized by clonal expansion of mast cells. When diagnosed in children, mastocytosis is commonly limited to the skin, which is named cutaneous mastocytosis (CM). According to its clinical presentation, CM can be classified into mastocytoma (M, 20% of cases), maculopapular CM (MPCM, 75%; previously urticaria pigmentosa (UP)) and diffuse cutaneous mastocytosis (DCM, 5%).1,2 Contrary to adult-onset mastocytosis, complete or partial resolution is commonly seen by adolescence.3 Serum...
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This study aimed to assess nasal airflow, nasal resistance, and the cross-sectional area of the nasal cavity in patients who have had maxillary superior repositioning (MSR). This is a cross-sectional study, and nasal airflow, nasal resistance, and the cross-sectional area of the nasal cavity were evaluated by rhinometry and acoustic rhinometry techniques in patients who had had MSR. Thirty-two patients were studied, and the mean (SD) MSR was 5.03 (1.61) (range 3-8) mm. There was a significant correlation...
TikTok™ is a mobile application (app) that has been downloaded over 1 billion times worldwide.1 The app generally contains short videos made by users (less than 30 seconds), which document a small story or narrative, with or without images and music. It is possible that many of the readers of BJOMS have heard of the app from their own children, albeit due to an annoying dance routine. A total of 41% of TikTok™ users are aged between 16–24,2 and on average, spend 52minutes a day viewing these uploaded...
Maxillofacial departments all over Italy were increasingly involved in facing the COVID-19 emergency. Elective surgeries have been progressively postponed to free beds and offer human and material sources.We compiled an inventory of 32 questions to evaluate the impact of SARS-COV2 epidemic on Maxillofacial Surgery in 23 selected Italian Maxillofacial departments. The questionnaire focused on three different aspects: the variation of the workload, showing both a reduction of the number of team members...
We read with great interest the editorial by Herron JBT et al1 on the Personal protective equipment (PPE) and coronavirus disease 2019 (COVID-19). The authors need to be complimented for a well-timed paper that addresses the current issue of exposure of health care workers to COVID 19.
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The outbreak of coronavirus disease 2019 (COVID-19) is rapidly changing our habits. To date, April 12, 2020, the virus has reached 209 nations, affecting 1.8 million people and causing more than 110,000 deaths. Maxillofacial surgery represents an example of a specialty that has had to adapt to this outbreak, because of the subspecialties of oncology and traumatology. The aim of this study was to examine the effect of this outbreak on the specialty of maxillofacial surgery and how the current situation...
Ectomesenchymal chondromyxoid tumour (ECT) is an extremely rare intraoral mesenchymal tumour. Most of these tumours have been identified on the anterior aspect of the dorsal surface of the tongue. ECT is difficult to diagnose because of its rarity. We report a case of ECT arising on the lateral border of the tongue in a 67-year-old woman. The tumour, measuring 20 × 10 mm in size, was surgically removed. Histopathologically, the tumour was composed of small polygonal cells arranged in sheets, with...
Immediate implant placement holds considerable value, yet primary implant stability is often a critical factor. The aim of this study was to evaluate the stability, volumetric viability, and buccal gap size of reverse tapered body shift (RTBS) implants after immediate placement. Peak insertion torque measurements of two RTBS designs (apical 40% vs. apical 50%), relative to conventionally tapered implants, were assessed in simulated extraction sockets prepared in synthetic bone blocks. Additionally,...
In patients with non-tuberculous mycobacterial cervicofacial lymphadenitis, incomplete surgical removal of infected lymph nodes leads to delayed healing and a higher recurrence rate, with eventual spontaneous drainage through the skin. However, complete surgical removal is not always achievable due to the extent of the infected tissue and proximity to vulnerable structures, such as the facial or accessory nerve. The aim of this study was to identify the clinical determinants of the (in)ability to...
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Abstract Purpose Although several trials have confirmed the treatment efficacy of induction chemotherapy followed by concurrent chemoradiotherapy (CCRT) in locoregionally advanced nasopharyngeal carcinoma (NPC) from endemic area of China, little is known about the best regime for induction chemotherapy in non-endemic region. This study compared the treatment effect of Gemcitabine and cisplatin (GP) versus docetaxel and cisplatin (TP)...
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Abstract Purpose The aim of this study was to assess the effect of vitamin D supplementation on ovulation rate in overweight subfertile women with PCOS undergoing ovulation induction. Methods This was a single center, parallel-groups, double-blind, and placebo-controlled randomized trial involving 186 eligible women undergoing induction of ovulation...
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