Cells, Vol. 9, Pages 1240: Circular RNA in Diseased Heart Cells doi: 10.3390/cells9051240 Authors: Wang Liu Heart disease remains the leading cause of death globally and leads to tremendous socio-economic burden. Despite advances in the field of cardiovascular research, novel theranostics are still in urgent need. Remarkable progress has been made in understanding aberrant protein interactions and signaling pathways in the diseased heart, but less is known regarding epigenetic regulation....
Sun May 17, 2020 03:00
Cells, Vol. 9, Pages 1241: HPV Infection Affects Human Sperm Functionality by Inhibition of Aquaporin-8 Cells doi: 10.3390/cells9051241 Authors: Giorgia Pellavio Federica Todaro Paola Alberizzi Claudia Scotti Giulia Gastaldi Marco Lolicato Claudia Omes Laura Caliogna Rossella E. Nappi Umberto Laforenza Human sperm cells express different aquaporins (AQPs), AQP3, 7, 8, 11, which are localized both in the plasma membrane and in intracellular structures. Besides...
Sun May 17, 2020 03:00
Cells, Vol. 9, Pages 1239: Anxiety and Depression Are Related to Higher Activity of Sphingolipid Metabolizing Enzymes in the Rat Brain Cells doi: 10.3390/cells9051239 Authors: Iulia Zoicas Christiane Mühle Anna K. Schmidtner Erich Gulbins Inga D. Neumann Johannes Kornhuber Changes in sphingolipid metabolism have been suggested to contribute to the pathophysiology of major depression. In this study, we investigated the activity of acid and neutral sphingomyelinases (ASM,...
Sun May 17, 2020 03:00
Cells, Vol. 9, Pages 1237: Exogenous Liposomal Ceramide-C6 Ameliorates Lipidomic Profile, Energy Homeostasis, and Anti-Oxidant Systems in NASH Cells doi: 10.3390/cells9051237 Authors: Francesca Zanieri Ana Levi David Montefusco Lisa Longato Francesco De Chiara Luca Frenguelli Sara Omenetti Fausto Andreola Tu Vinh Luong Veronica Massey Juan Caballeria Constantino Fondevila Sriram S Shanmugavelandy Todd Fox Giuseppe Mazza Josepmaria Argemi Ramon...
Sat May 16, 2020 03:00
Cells, Vol. 9, Pages 1238: Functional Characterization of Neurofilament Light Splicing and Misbalance in Zebrafish Cells doi: 10.3390/cells9051238 Authors: Doris Lou Demy Maria Letizia Campanari Raphael Munoz-Ruiz Heather D. Durham Benoit J. Gentil Edor Kabashi Neurofilaments (NFs), a major cytoskeletal component of motor neurons, play a key role in the differentiation, establishment and maintenance of their morphology and mechanical strength. The de novo assembly of these...
Sat May 16, 2020 03:00
Cells, Vol. 9, Pages 1235: Fractionation-Dependent Radiosensitization by Molecular Targeting of Nek1
Cells, Vol. 9, Pages 1235: Fractionation-Dependent Radiosensitization by Molecular Targeting of Nek1 Cells doi: 10.3390/cells9051235 Authors: Freund Hehlgans Martin Ensminger Fokas Rödel Löbrich Rödel NIMA (never-in-mitosis gene A)-related kinase 1 (Nek1) is shown to impact on different cellular pathways such as DNA repair, checkpoint activation, and apoptosis. Its role as a molecular target for radiation sensitization of malignant cells, however, remains...
Sat May 16, 2020 03:00
Cells, Vol. 9, Pages 1236: Understanding Glioblastoma Biomarkers: Knocking a Mountain with a Hammer Cells doi: 10.3390/cells9051236 Authors: Malak Hassn Mesrati Amir Barzegar Behrooz Asmaa Y. Abuhamad Amir Syahir Gliomas are the most frequent and deadly form of human primary brain tumors. Among them, the most common and aggressive type is the high-grade glioblastoma multiforme (GBM), which rapidly grows and renders patients a very poor prognosis. Meanwhile, cancer stem cells...
Sat May 16, 2020 03:00
Cells, Vol. 9, Pages 1234: The Role of Gut Microbiota Biomodulators on Mucosal Immunity and Intestinal Inflammation Cells doi: 10.3390/cells9051234 Authors: Chiara Amoroso Federica Perillo Francesco Strati Massimo Fantini Flavio Caprioli Federica Facciotti Alterations of the gut microbiota may cause dysregulated mucosal immune responses leading to the onset of inflammatory bowel diseases (IBD) in genetically susceptible hosts. Restoring immune homeostasis through the normalization...
Sat May 16, 2020 03:00
Cells, Vol. 9, Pages 1233: The Influence of Palmatine Isolated from Berberis sibirica Radix on Pentylenetetrazole-Induced Seizures in Zebrafish Cells doi: 10.3390/cells9051233 Authors: Gawel Kukula-Koch Nieoczym Stepnik Ent Banono Tarabasz Turski Esguerra Palmatine (PALM) and berberine (BERB) are widely identified isoquinoline alkaloids among the representatives of the Berberidaceae botanical family. The antiseizure activity of BERB was shown previously...
Sat May 16, 2020 03:00
Cells, Vol. 9, Pages 1232: Nutraceutical Activity in Osteoarthritis Biology: A Focus on the Nutrigenomic Role Cells doi: 10.3390/cells9051232 Authors: Stefania D'Adamo Silvia Cetrullo Veronica Panichi Erminia Mariani Flavio Flamigni Rosa Maria Borzì Osteoarthritis (OA) is a disease associated to age or conditions that precipitate aging of articular cartilage, a post-mitotic tissue that remains functional until the failure of major homeostatic mechanisms. OA severely impacts...
Sat May 16, 2020 03:00
Cells, Vol. 9, Pages 1231: Focus on the Role of Klotho Protein in Neuro-Immune Interactions in HT-22 Cells Upon LPS Stimulation Cells doi: 10.3390/cells9051231 Authors: Rusinek Sołek Tabęcka-Łonczyńska Koziorowski Mytych Neuroinflammation is defined as the activation of the brain's innate immune system in response to an inflammatory challenge and is considered to be a prominent feature of neurodegenerative diseases. The contribution of overactivated neuroglial cells...
Sat May 16, 2020 03:00
Cells, Vol. 9, Pages 1230: Lactulose and Melibiose Inhibit α-Synuclein Aggregation and Up-Regulate Autophagy to Reduce Neuronal Vulnerability Cells doi: 10.3390/cells9051230 Authors: Chiung Mei Chen Chih-Hsin Lin Yih-Ru Wu Chien-Yu Yen Yu-Ting Huang Jia-Lan Lin Chung-Yin Lin Wan-Ling Chen Chih-Ying Chao Guey-Jen Lee-Chen Ming-Tsan Su Kuo-Hsuan Chang Parkinson’s disease (PD) is a neurodegenerative disease characterized by selective dopaminergic...
Sat May 16, 2020 03:00
Cells, Vol. 9, Pages 1229: CTRP9 Mediates Protective Effects in Cardiomyocytes via AMPK- and Adiponectin Receptor-Mediated Induction of Anti-Oxidant Response Cells doi: 10.3390/cells9051229 Authors: Bernd Niemann Ling Li Dorothee Siegler Benedikt H. Siegler Fabienne Knapp Jakob Hanna Muhammad Aslam Michael Kracht Rainer Schulz Susanne Rohrbach The C1q/tumor necrosis factor-alpha-related protein 9 (CTRP9) has been reported to exert cardioprotective effects,...
Fri May 15, 2020 03:00
Cells, Vol. 9, Pages 1227: Liver Sinusoidal Endothelial Cells Contribute to Hepatic Antigen-Presenting Cell Function and Th17 Expansion in Cirrhosis Cells doi: 10.3390/cells9051227 Authors: Esther Caparrós Oriol Juanola Isabel Gómez-Hurtado Amaya Puig-Kroger Paula Piñero Pedro Zapater Raquel Linares Fabián Tarín Sebastián Martínez-López Jordi Gracia-Sancho José M. González-Navajas Rubén Francés Hepatic immune function is compromised during cirrhosis....
Fri May 15, 2020 03:00
Cells, Vol. 9, Pages 1228: Knockdown of the Ribosomal Protein eL29 in Mammalian Cells Leads to Significant Changes in Gene Expression at the Transcription Level Cells doi: 10.3390/cells9051228 Authors: Alexander V. Gopanenko Alena V. Kolobova Maria I. Meschaninova Alya G. Venyaminova Alexey E. Tupikin Marsel R. Kabilov Alexey A. Malygin Galina G. Karpova An imbalance in the synthesis of ribosomal proteins can lead to the disruption of various cellular processes....
Fri May 15, 2020 03:00
Cells, Vol. 9, Pages 1225: Current Challenges in Providing Good Leukapheresis Products for Manufacturing of CAR-T Cells for Patients with Relapsed/Refractory NHL or ALL Cells doi: 10.3390/cells9051225 Authors: Felix Korell Sascha Laier Sandra Sauer Kaya Veelken Hannah Hennemann Maria-Luisa Schubert Tim Sauer Petra Pavel Carsten Mueller-Tidow Peter Dreger Michael Schmitt Anita Schmitt Background: T lymphocyte collection through leukapheresis is an essential...
Fri May 15, 2020 03:00
Cells, Vol. 9, Pages 1224: M2 Macrophages Infiltrating Epithelial Ovarian Cancer Express MDR1: A Feature That May Account for the Poor Prognosis Cells doi: 10.3390/cells9051224 Authors: Susann Badmann Sabine Heublein Doris Mayr Anna Reischer Yue Liao Thomas Kolben Susanne Beyer Anna Hester Christine Zeder-Goess Alexander Burges Sven Mahner Udo Jeschke Fabian Trillsch Bastian Czogalla Multi drug resistance protein 1 (MDR1) expression on tumor cells...
Fri May 15, 2020 03:00
Cells, Vol. 9, Pages 1226: In Vitro Effects of Streptococcus oralis Biofilm on Peri-Implant Soft Tissue Cells Cells doi: 10.3390/cells9051226 Authors: Alexandra Ingendoh-Tsakmakidis Jörg Eberhard Christine S. Falk Meike Stiesch Andreas Winkel Human gingival epithelial cells (HGEps) and fibroblasts (HGFs) are the main cell types in peri-implant soft tissue. HGEps are constantly exposed to bacteria, but HGFs are protected by connective tissue as long as the mucosa–implant...
Fri May 15, 2020 03:00
Cells, Vol. 9, Pages 1223: TNFα Rescues Dendritic Cell Development in Hematopoietic Stem and Progenitor Cells Lacking C/EBPα Cells doi: 10.3390/cells9051223 Authors: Subramanian Anirudh Angelika Rosenberger Elke Schwarzenberger Carolin Schaefer Herbert Strobl Armin Zebisch Heinz Sill Albert Wölfler Dendritic cells (DCs) are crucial effectors of the immune system, which are formed from hematopoietic stem and progenitor cells (HSPCs) by a multistep process regulated...
Fri May 15, 2020 03:00
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