Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Jiwei Ye, Mingquan Gao, Xinwu Guo, Henan Zhang, Fuchun Jiang
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Jian-Hua Chang, Mei-Mei Jin, Jun-Tian Liu
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Zhishen Xie, Gai Gao, Hui Wang, Erwen Li, Yong Yuan, Jiangyan Xu, Zhenqiang Zhang, Pan Wang, Yu Fu, Huahui Zeng, Junying Song, Christian Hölscher, Hui Chen
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Rosana H.C.N. Freitas, Juliana M.C. Barbosa, Patrícia Bernardino, Vitor Sueth-Santiago, Solange M.S.V. Wardell, James L. Wardell, Débora Decoté-Ricardo, Tatiana G. Melo, Edson F. da Silva, Kelly Salomão, Carlos A.M. Fraga
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Zhirui Yang, Guofeng Pan, Luyong Zhang, Dan Yan
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Biming Zhan, Zongyu Xu, Yang Zhang, Kefei Wan, Hanyue Deng, Dimeng Wang, Huihui Bao, Qinghua Wu, Xiaohong Hu, Hong Wang, Xiao Huang, Xiaoshu Cheng
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Gerardo D. Anaya-Eugenio, Choon Yong Tan, L. Harinantenaina Rakotondraibe, Esperanza Carcache Carcache de Blanco
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Z. Kutlu, M. Celik, A. Bilen, Z. Halıcı, S. Yıldırım, S. Karabulut, S. Karakaya, Delimustafaoğlu F. Bostanlık, P. Aydın
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Chengke Luo, Shengchao Xu, Gan Dai, Zhiqiang Xiao, Ling Chen, Zhixiong Liu
Abstract Background Obstructive sleep apnea (OSA) is associated with an increased risk of developing atherosclerotic cardiovascular disease (ASCVD). Patients with OSA have increased levels of oxidative stress and several studies have shown higher levels of oxidative stress markers. Oxidized-LDL (Ox-LDL) is an important risk factor for ASCVD and a number of studies have measured its levels in patients with OSA, though results from these...
Abstract Introduction Sleep problems, including obstructive sleep apnea (OSA), profoundly affect quality of life in patients with systemic sclerosis (SSc). This study aimed to determine the prevalence of OSA in patients with SSc and the factors affecting OSA. Methods Consecutive patients with SSc lung involvement who were referred to the “Outpatient...
Abstract Objective Previous studies suggest a relationship between sleep disordered breathing (SDB) and lower extremity artery disease (LEAD) though disagreements remain. This study was performed to assess the association between SDB and LEAD in a metaanalysis. Methods PubMed and Embase databases were searched for observational studies. A random-effects...
Abstract Purpose Obstructive sleep apnoea (OSA) involves recurrent obstructive apnoeas and hypopnoeas which cause cyclic hypoxia, reoxygenation and formation of reactive oxygen species (ROS). We aimed to investigate a member of the nicotinamide adenine dinucleotide phosphate oxidase (NOX) family of enzymes, specifically (NOX4), not previously studied in humans, as well as 8-OHdG/106dG, MDA and IMA, which are known to be associated with...
Abstract Purpose Poor quality of sleep is a common feature in patients with various lung diseases and affects their health-related quality of life (HRQL). We evaluated sleep quality and HRQL in patients on the waitlist for lung transplantation in Japan. Methods In this prospective study, patient-reported and physiological data were collected from patients...
Zusammenfassung Eine Vielzahl neuer implantierbarer Hörsysteme und Anwendungen eröffnet zusätzliche Möglichkeiten für bisher schlecht behandelbare Erkrankungen. Für viele dieser Hörsysteme gibt es nur eingeschränkt technische Möglichkeiten, um alle Anwendungen technisch zu charakterisieren. Deswegen sind klar strukturierte, klinische Studien, die die Anwendungen und Geräte für zusammenfassende Metastudien vergleichbar machen, dringend erforderlich. Dies ist nicht nur im Hinblick...
Zusammenfassung Exosomen, virusgroße Nanovesikel, werden als Botensysteme unseres Körpers zur Kommunikation mit anderen Körperzellen und Regulation von Immunfunktionen genutzt. Die von fast allen Körperzellen sezernierten Exosomen können unterwegs in der Blutzirkulation und in der Körperperipherie mit Immunzellen interagieren. Unterschiedliche Marker auf der Exosomenoberfläche sind für die Immunzelladhäsion und -interaktion nötig. Darüber hinaus sind mehrere Arten der Exosomen-Immunzell-Interaktion...
About half of head and neck squamous cell carcinoma (HNSCC) patients present with advanced stage disease. In the case of hypopharyngeal, laryngeal and HPV-negative oropharyngeal carcinomas, chemoradiotherapy is the current treatment of choice for these patients[1]. Disease progression occurs in around 40%, stressing the need for additional treatment options for poor prognosis patients.
The brainstem is composed of several densely packed neural tracts that are critical for neurological function and survival. Progressing lesions near or on the brainstem often lead to rapid neurological decline and even death.[1-6] A 2017 study by Emery et al. found that brainstem metastases are associated with more than a three-fold risk of death when compared to supratentorial lesions.[7] Resection is typically avoided as a treatment option due to operative risk and poor outcomes, and instead, stereotactic...
In breast conserving treatment (BCT), radiation therapy following breast-conserving surgery (BCS) is performed as whole breast irradiation (WBI) or, increasingly, as accelerated partial breast irradiation (APBI), targeting the tissue surrounding the original tumour site (tumour bed) in selected patients with low local recurrence risks [1].
Radiation-cystitis is an unavoidable side effect of external beam radiation therapy to the pelvis, even when delivered using normal tissue sparing delivery methods such as image guided radiation therapy (IGRT) and volumetric modulated arc therapy (VMAT). Cystitis symptoms include dysuria, urinary frequency, urgency, nocturia, the sensation of incomplete bladder voiding, haematuria and an increased risk of urinary tract infections. Acute radiation-cystitis develops during radiation therapy and generally...
Conflict of Interest: DGK is on the scientific advisory board and owns stock in Lumicell, Inc which is developing intraoperative imaging technology. DGK is a co-founder of X-RAD Therapeutics, which is developing radiosensitizers. DGK reports research support from Merck, Bristol Myers Squibb, and X-RAD Therapeutics. MD reports research funding from Varian Medical Systems and Illumina, ownership interest in CiberMed, patent filings related to cancer biomarkers, paid consultancy from Roche, AstraZeneca,...
Italy experienced one of the world’s deadliest COVID-19 outbreaks and healthcare systems had to instantly reorganise activity. The Italian Radiation Oncology Departments adapted numerous solutions to minimize the disruptions. Information technologies, treatment prioritization and implementation of hypofractionation and protection procedures allowed balancing between cancer patient care and patient/healthcare workers safety.
Publication date: Available online 11 May 2020Source: Acta Otorrinolaringológica EspañolaAuthor(s): Jordi Coromina Isern, Robert Soler Rich, Joan Rius Tarruella, Jeanneth Zamora Bustamante
Publication date: Available online 12 May 2020Source: Journal of Communication DisordersAuthor(s): Kim Bettens, Cassandra Alighieri, Laura Bruneel, Lara De Meulemeester, Kristiane Van Lierde
ObjectivesThere are established methods for occupational epidemiological cohort analysis, such as proportional hazards regression, that are well suited to aetiological research and yield parameter estimates that allow for succinct communication among academics. However, these methods are not necessarily well suited for evaluation of health impacts of policy choices and communication to decision makers. An informed decision about a policy that impacts health and safety requires a valid estimate of...
ObjectivesA historical cohort study of cancer mortality is being conducted among workers in a chrysotile mine and its enrichment factories in the town of Asbest, Russian Federation. Because individual-level information on tobacco use is not available for Asbest Chrysotile Cohort members, a cross-sectional survey of smoking behaviours was conducted among active and retired workers.MethodsSelf-administered questionnaires were completed by active workers during meetings organised by occupational safety...
Publication date: Available online 12 May 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Carlota F. Prendes, Christina Christersson, Kevin Mani
Tue May 12, 2020 19:50
Publication date: Available online 12 May 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Andrés Reyes Valdivia, Claudio Gandarias Zúñiga, Vicente Riambau
Tue May 12, 2020 19:50
Publication date: Available online 12 May 2020Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Alexandros Mallios, William C. Jennings
Tue May 12, 2020 19:50
The name of author Do Hoon Lim was incorrect in the initial online publication. The original article has been corrected.
Background. Few biomarkers are available for early identification of pulmonary arterial hypertension (PAH) and interstitial lung disease (ILD) in systemic sclerosis (SS) and scleroderma spectrum disorders (SSD). Aims. To evaluate Gas6, sAxl, and sMer as biomarkers for cardiopulmonary complications of SS and SSD. Methods. In a cross-sectional observational study, we recruited 125 consecutive patients, affected by SS and SSD and referred to a tertiary-level pulmonary hypertension outpatient clinic....
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01318
Abstract Introduction Diabetes has been proposed as a risk factor for increased skeletal fragility. Visceral fat is known to yield adverse effects on bone metabolism in people with diabetes. We investigated the relationship between the change in visceral fat mass over time and TBS or BMD. Materials and methods This retrospective study enrolled 690...
Abstract Pancreatic neuroendocrine tumors (PanNETs) are rare neoplasms that include even rarer variants that may pose different diagnostic problems, especially in fine needle aspiration cytology (FNAC). We describe the diagnostic clues of the amyloid-rich variant of PanNETs in endoscopic ultrasound (EUS)–guided fine needle aspiration cytology (EUS-FNAC). Three cases of PanNETs with an amyloid-rich stromal component were retrieved and retrospectively reviewed. For every case, the...
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c00861
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c04091
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02221
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02240
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c00807
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