Abstract Background Paroxysmal kinesigenic dyskinesia is a spectrum of involuntary dyskinetic disorders with high clinical and genetic heterogeneity. Mutations in proline‐rich transmembrane protein 2 have been identified as the major pathogenic factor. Objectives We analyzed 600 paroxysmal kinesigenic dyskinesia patients nationwide who were identified by the China Paroxysmal Dyskinesia Collaborative Group to summarize the clinical phenotypes and genetic features of paroxysmal kinesigenic...
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Related ArticlesEffects of Periosteal Elevation Before Lateral Osteotomy in Rhinoplasty: A Meta-Analysis of Randomized Controlled Trials. Clin Exp Otorhinolaryngol. 2020 May 12;: Authors: Kim JS, Kim SH, Lee H, Kim BG, Hwang SH Abstract Although osteotomy is an important part of rhinoplasty, it is known to be closely related to postoperative eyelid edema and ecchymosis. We evaluated the effects of periosteal elevation prior to osteotomy on eyelid...
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Related ArticlesSneezing and Rubbing Counts in Allergic Rhinitis Mouse Models Are a Reliable Indicator of Type 2 Immune Response. Clin Exp Otorhinolaryngol. 2020 May 12;: Authors: Ryu G, Bae JS, Kim JH, Kim EH, Chung YJ, Mo JH PMID: 32392641 [PubMed - as supplied by publisher]
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Related ArticlesManagement of Laryngopharyngeal Reflux in Asia. Clin Exp Otorhinolaryngol. 2020 May 12;: Authors: Kim SI, Lechien JR, Ayad T, Jia H, Khoddami SM, Enver N, Raghunandhan SK, Hamdan AL, Eun YG Abstract Objectives: This study was conducted to investigate the current practices of Asian otolaryngologists for laryngopharyngeal reflux (LPR). Methods: An online survey about LPR was sent to 2,000 members of Asian otolaryngological...
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Related ArticlesLycium barbarum Polysaccharide Extracted from Lycium barbarum Leaves Ameliorates Asthma in Mice by Reducing Inflammation and Modulating Gut Microbiota. J Med Food. 2020 May 11;: Authors: Cui F, Shi CL, Zhou XJ, Wen W, Gao XP, Wang LY, He B, Yin M, Zhao JQ Abstract This study was designed to explore the impact of Lycium barbarum polysaccharide (LBP) on inflammation and gut microbiota in mice with allergic asthma. Mice were divided...
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Related ArticlesChanges in Nasal Staphylococcus Colonization and Infection Rates After Nasal Surgery. Facial Plast Surg Aesthet Med. 2020 May 11;: Authors: Swegal W, Deeb R, Greene J, Peterson E, Perri MB, Bardossy AC, Zervos M, Jones LR Abstract Background: The relationship between nasal flora and infection rates in patients undergoing nasal surgery is of interest. This relationship has been studied though changes that may take place due to surgery...
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Related ArticlesDoes obesity cause thyroid cancer? A Mendelian randomization study. J Clin Endocrinol Metab. 2020 May 11;: Authors: Fussey JM, Beaumont RN, Wood AR, Vaidya B, Smith J, Tyrrell J Abstract BACKGROUND: The incidence of thyroid cancer is rising, and relatively little is known about modifiable risk factors for the condition. Observational studies have suggested a link between adiposity and thyroid cancer. However, these are subject to...
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Related ArticlesIs postural dysfunction related to sarcopenia? A population-based study. PLoS One. 2020;15(5):e0232135 Authors: Kim AY, Lee JK, Kim SH, Choi J, Song JJ, Chae SW Abstract Postural dysfunction is one of the most common community health symptoms and frequent chief complaints in hospitals. Sarcopenia is a syndrome characterized by degenerative loss of skeletal muscle mass, muscle quality, and muscle strength, and is the main contributor...
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Related ArticlesQuantitative Imaging Informatics for Cancer Research. JCO Clin Cancer Inform. 2020 May;4:444-453 Authors: Fedorov A, Beichel R, Kalpathy-Cramer J, Clunie D, Onken M, Riesmeier J, Herz C, Bauer C, Beers A, Fillion-Robin JC, Lasso A, Pinter C, Pieper S, Nolden M, Maier-Hein K, Herrmann MD, Saltz J, Prior F, Fennessy F, Buatti J, Kikinis R Abstract PURPOSE: We summarize Quantitative Imaging Informatics for Cancer Research (QIICR; U24...
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Related ArticlesBest Practices for Adapting and Delivering Community-Based Yoga for People with Traumatic Brain Injury in the United States and Canada. Int J Yoga Therap. 2020 May 11;: Authors: Chauhan N, Zeller S, Donnelly KZ Abstract Emerging benefits of yoga for traumatic brain injury (TBI) suggest that broader accessibility to community-based yoga programming is important. This cross-sectional, mixed methods study sought to identify best practices...
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Related ArticlesIt's Time For Mohs: Micrographic Surgery For The Treatment Of High-Risk Basal Cell Carcinomas Of The Head And Neck Region. Dermatol Ther. 2020 May 11;:e13474 Authors: Dika E, Veronesi G, Patrizi A, De Salvo S, Misciali C, Baraldi C, Mussi M, Fabbri E, Tartari F, Lambertini M Abstract Basal cell carcinoma (BCC) is the most common variety of non-melanoma skin cancer and its incidence is rising worldwide. The centrofacial sites (area...
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Related ArticlesConservative management of oesophageal soft food bolus impaction. Cochrane Database Syst Rev. 2020 May 11;5:CD007352 Authors: Hardman J, Sharma N, Smith J, Nankivell P Abstract BACKGROUND: Impaction of a soft food bolus in the oesophagus causes dysphagia and regurgitation. If the bolus does not pass spontaneously, then the patient is at risk of aspiration, dehydration, perforation, and death. Definitive management is with endoscopic...
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Related ArticlesPrimary vs nodal site PET/CT response as a prognostic marker in oropharyngeal squamous cell carcinoma treated with intensity-modulated radiation therapy. Head Neck. 2020 May 11;: Authors: Eckstein JM, Nolan N, Healy E, Wright CL, Jain A, Barney CL, Washington I, McElroy JP, Grecula JC, Wobb JL, Mitchell DL, Miller E, Gamez M, Blakaj D, Diavolitsis V, Bhatt A Abstract BACKGROUND: Positron emission tomography/computed tomography (PET/CT)...
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Related ArticlesClinical Significance of an m6A Reader Gene, IGF2BP2, in Head and Neck Squamous Cell Carcinoma. Front Mol Biosci. 2020;7:68 Authors: Deng X, Jiang Q, Liu Z, Chen W Abstract The importance of N6-methyladenosine (m6A) in tumor recurrence and prognosis has been recognized in recent years. The role of m6A readers, such as insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2), in regulating head and neck squamous cell carcinoma...
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Related ArticlesEffects of Surgery on Survival of Early-Stage Patients With SCLC: Propensity Score Analysis and Nomogram Construction in SEER Database. Front Oncol. 2020;10:626 Authors: Wang Y, Zheng Q, Jia B, An T, Zhao J, Wu M, Zhuo M, Li J, Zhong J, Chen H, Yang X, Chi Y, Dong Z, Sepesi B, Zhang J, Gay CM, Wang Z Abstract Purpose: We aimed to assess the survival benefit of surgery for patients with stage IA-IIB small cell lung cancer (SCLC) and...
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Response of the Istituto Nazionale Tumori of Milan Head & Neck Cancer Unit to the COVID-19 outbreak.
Related ArticlesResponse of the Istituto Nazionale Tumori of Milan Head & Neck Cancer Unit to the COVID-19 outbreak. Cancers Head Neck. 2020;5:7 Authors: Resteghini C, Maggioni P, Di Martino V, Licitra L, Head and Neck Cancer Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori Milan, Italy PMID: 32391172 [PubMed]
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Related ArticlesApplications of radiomics in precision diagnosis, prognostication and treatment planning of head and neck squamous cell carcinomas. Cancers Head Neck. 2020;5:6 Authors: Haider SP, Burtness B, Yarbrough WG, Payabvash S Abstract Recent advancements in computational power, machine learning, and artificial intelligence technology have enabled automated evaluation of medical images to generate quantitative diagnostic and prognostic biomarkers....
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Related ArticlesAging-associated genes TNFRSF12A and CHI3L1 contribute to thyroid cancer: An evidence for the involvement of hypoxia as a driver. Oncol Lett. 2020 Jun;19(6):3634-3642 Authors: Lian M, Cao H, Baranova A, Kural KC, Hou L, He S, Shao Q, Fang J Abstract The prevalence of thyroid cancer (TC) is high in the elderly. The present study was based on the hypothesis that genes, which have increased activity with aging, may play a role in the...
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Related ArticlesAsian Sand Dust Particles Increased Pneumococcal Biofilm Formation in vitro and Colonization in Human Middle Ear Epithelial Cells and Rat Middle Ear Mucosa. Front Genet. 2020;11:323 Authors: Yadav MK, Go YY, Chae SW, Park MK, Song JJ Abstract Introduction: Air pollutants such as Asian sand dust (ASD) and Streptococcus pneumoniae are risk factors for otitis media (OM). In this study, we evaluate the role of ASD in pneumococcal in vitro...
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Related ArticlesGenomics of Otitis Media (OM): Molecular Genetics Approaches to Characterize Disease Pathophysiology. Front Genet. 2020;11:313 Authors: Giese APJ, Ali S, Isaiah A, Aziz I, Riazuddin S, Ahmed ZM Abstract Otitis media (OM) is an infective and inflammatory disorder known to be a major cause of hearing impairment across all age groups. Both acute and chronic OM result in substantial healthcare utilization related to antibiotic prescription...
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Related ArticlesDose-Dependent Transient Decrease of Impedances by Deep Intracochlear Injection of Triamcinolone With a Cochlear Catheter Prior to Cochlear Implantation-1 Year Data. Front Neurol. 2020;11:258 Authors: Prenzler NK, Salcher R, Lenarz T, Gaertner L, Warnecke A Abstract Administration of low-dose steroids via a catheter inserted into the cochlea to apply pharmaceuticals to more apical regions was previously shown not to be sufficient...
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Related ArticlesRevision Surgery of the Cleft Palate. Semin Plast Surg. 2020 May;34(2):120-128 Authors: Hu S, Levinson J, Rousso JJ Abstract Cleft palate repairs often require secondary surgeries and/or revisions for a variety of reasons. The most common causes are symptomatic oronasal fistulas and velopharyngeal insufficiency. Complications from primary surgery, such as wound dehiscence, infection, and hematomas, contribute to the relatively high...
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Related ArticlesOsteoradionecrosis of the Maxilla: Conservative Management and Reconstructive Considerations. Semin Plast Surg. 2020 May;34(2):106-113 Authors: Shokri T, Wang W, Vincent A, Cohn JE, Kadakia S, Ducic Y Abstract The implementation of radiotherapy in the multimodal treatment of advanced head and neck cancer has greatly improved survival rates. In some patients, however, this benefit comes at the potential expense of the tissue surrounding...
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Related ArticlesTranspalatal Approaches to the Skull Base and Reconstruction: Indications, Technique, and Associated Morbidity. Semin Plast Surg. 2020 May;34(2):99-105 Authors: London NR, Chan JYW, Carrau RL Abstract Multiple anterior surgical approaches are available to obtain access to the nasopharynx, clivus, and craniocervical junction. These include the direct and transoral robotic surgery transpalatal, maxillary swing, and endoscopic endonasal...
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Related ArticlesPremaxillary Deficiency: Techniques in Augmentation and Reconstruction. Semin Plast Surg. 2020 May;34(2):92-98 Authors: Shokri T, Wang W, Cohn JE, Kadakia S, Ducic Y Abstract Progressive premaxillary retrusion is a common sequela of the facial aging process. In most cases, this manifests with central maxillary recession. Central maxillary insufficiency is also commonly encountered within certain ethnic communities, or in cleft lip...
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Related ArticlesPalatomaxillary Reconstruction: Fibula or Scapula. Semin Plast Surg. 2020 May;34(2):86-91 Authors: Badhey AK, Khan MN Abstract Palatomaxillary reconstruction presents a unique challenge for the reconstructive surgeon. The maxillofacial skeleton preserves critical aerodigestive functions-it provides a stable hard palate to support mastication and separate the nasal and oral cavities, and buttress support to provide adequate midface...
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Related ArticlesReconstruction of the Midface and Palate. Semin Plast Surg. 2020 May;34(2):77-85 Authors: Bender-Heine A, Wax MK Abstract The midface is a complex anatomic structure that is fundamental to many physiologic and homeostatic functions. It may be involved in many pathologic processes that require partial or complete removal. When this happens, reconstruction is mandatory to improve cosmetic outcome with its effect on social interaction...
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Related ArticlesSurgery of the Palatomaxillary Structure. Semin Plast Surg. 2020 May;34(2):71-76 Authors: Jategaonkar AA, Kaul VF, Lee E, Genden EM Abstract The palatomaxillary structure plays critical roles in both form and function of the midface. Surgical defects of the palate and maxilla can be associated with significant morbidity and deformity. Various defect classification systems have been used to assist in reconstruction and rehabilitation....
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Related ArticlesInjuries in Male and Female Elite Aquatic Sports Athletes: An 8-Year Prospective, Epidemiological Study. J Sports Sci Med. 2020 Jun;19(2):390-396 Authors: Kim HC, Park KJ Abstract This study aimed to determine the injury patterns associated with training activities in elite South Korean aquatic sports athletes training for the Olympic Games. From 2012 to 2019, we prospectively collected data on elite aquatic sports athletes at the...
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Related ArticlesGeographic Variation in Epistaxis Interventions Among Medicare Beneficiaries. Ann Otol Rhinol Laryngol. 2020 May 11;:3489420923380 Authors: Hur K, Badash I, Talmor G, Ference EH, Wrobel BB Abstract OBJECTIVES: To quantify the utilization of epistaxis procedures in the elderly population and assess whether the geographic variability of these procedures is associated with hypertension and direct oral anticoagulant (DOAC) use. ...
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Related ArticlesHemifacial Spasm as a Rare Clinical Presentation of Idiopathic Intracranial Hypertension: Case Report and Literature Review. Ann Otol Rhinol Laryngol. 2020 May 11;:3489420920319 Authors: Poff CB, Lipschitz N, Kohlberg GD, Breen JT, Samy RN Abstract OBJECTIVES: To report a rare case of idiopathic intracranial hypertension (IIH) presenting with hemifacial spasm (HFS) and review the current literature. METHODS: Case report...
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Related ArticlesCell Surface Labeling by Engineered Extracellular Vesicles. Adv Biosyst. 2020 May 10;:e2000007 Authors: Hamilton N, Claudio NM, Armstrong RJ, Pucci F Abstract Extracellular vesicles (EVs) can mediate local and long-range intercellular communication via cell surface signaling. In order to perform in vivo studies of unmanipulated, endogenously released EVs, sensitive but stringent approaches able to detect EV-cell surface interactions...
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Related ArticlesClassification of Hyperspectral Endocrine Tissue Images Using Support Vector Machines. Int J Med Robot. 2020 May 10;:e2121 Authors: Maktabi M, Köhler H, Ivanova M, Neumuth T, Rayes N, Seidemann L, Sucher R, Jansen-Winkeln B, Gockel I, Barberio M, Chalopin C Abstract Thyroidectomy is one of the most commonly performed surgical procedures. The region of the neck has a very complex structural organization. It would be beneficial to introduce...
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Related ArticlesDevelopment of Acellular Respiratory Mucosal Matrix Using Porcine Tracheal Mucosa. Tissue Eng Regen Med. 2020 May 10;: Authors: Jung SY, Tran AN, Kim HY, Choi E, Lee SJ, Kim HS Abstract BACKGROUND: Respiratory mucosa defects result in airway obstruction and infection, requiring subsequent functional recovery of the respiratory epithelium. Because site-specific extracellular matrix (ECM) facilitates restoration of organ function by...
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Related ArticlesBeyond broadband: digital inclusion as a driver of inequities in access to rural cancer care. J Cancer Surviv. 2020 May 11;: Authors: DeGuzman PB, Bernacchi V, Cupp CA, Dunn B, Ghamandi BJF, Hinton ID, Jameson MJ, Lewandowski DL, Sheffield C Abstract PURPOSE: Rural cancer survivors have worse quality of life than their urban counterparts. Telemedicine is a potential solution to connecting rural residents with specialized cancer providers...
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Related ArticlesThe role of nonacid reflux in laryngopharyngeal reflux diseases. Eur Arch Otorhinolaryngol. 2020 May 10;: Authors: Li J, Wang J, Wu M, Zhao J, Guo H Abstract OBJECTIVE: To analyze the role of nonacid reflux in laryngopharyngeal reflux diseases (LPRD). METHODS: From January 2014 to April 2019, 344 patients associated with LPRD underwent 24-h multichannel intraluminal impedance-pH monitoring, and their reflux symptom index...
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Related ArticlesFeasibility of CT quantification of intratumoural 166Ho-microspheres. Eur Radiol Exp. 2020 May 11;4(1):29 Authors: C Bakker R, Bastiaannet R, van Nimwegen SA, D Barten-van Rijbroek A, Van Es RJJ, Rosenberg AJWP, de Jong HWAM, Lam MGEH, Nijsen JFW Abstract BACKGROUND: Microspheres loaded with radioactive 166Ho (166Ho-MS) are novel particles for radioembolisation and intratumoural treatment. Because of the limited penetration of β radiation,...
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Related ArticlesProgrammed Death Ligand 1 Heterogeneity and its Impact on Benefit from Immune Checkpoint Inhibitors in Non-Small-Cell Lung Cancer. J Thorac Oncol. 2020 May 07;: Authors: Hong L, Negrao MV, Dibaj SS, Chen R, Reuben A, Bohac JM, Liu X, Skoulidis F, Gay CM, Cascone T, Mitchell KG, Tran HT, Le X, Byers LA, Sepesi B, Altan M, Elamin YY, Fossella FV, Kurie JM, Lu C, Mott FE, Tsao AS, Rinsurongkawong W, Lewis J, Gibbons DL, Glisson BS, Blumenschein GR, Roarty...
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