Veterinary Sciences, Vol. 7, Pages 63: Characterizing the Role of SMYD2 in Mammalian Embryogenesis—Future Directions Veterinary Sciences doi: 10.3390/vetsci7020063 Authors: Dillon K. Jarrell Kelly N. Hassell Debbie C. Crans Shari Lanning Mark A. Brown The SET and MYND domain-containing (SMYD) family of lysine methyltransferases are essential in several mammalian developmental pathways. Although predominantly expressed in the heart, the role of SMYD2 in heart development has...
Tue May 12, 2020 03:00
Veterinary Sciences, Vol. 7, Pages 62: Canine Epithelial Skin Tumours: Expression of the Stem Cell Markers Lgr5, Lgr6 and Sox9 in Light of New Cancer Stem Cell Theories Veterinary Sciences doi: 10.3390/vetsci7020062 Authors: Laura Bongiovanni Chiara Brachelente Eva Moreno Monika M. Welle Evidence is accumulating that tumour development is driven by cancer stem cells (CSCs). In order to understand the presence and potential contribution of stem cells (SCs) as tumour-initiating...
Fri May 08, 2020 03:00
Viruses, Vol. 12, Pages 533: Cell Culture Systems and Drug Targets for Hepatitis A Virus Infection Viruses doi: 10.3390/v12050533 Authors: Tatsuo Kanda Reina Sasaki Ryota Masuzaki Naoki Matsumoto Masahiro Ogawa Mitsuhiko Moriyama Hepatitis A virus (HAV) infection is one of the major causes of acute hepatitis, and this infection occasionally causes acute liver failure. HAV infection is associated with HAV-contaminated food and water as well as sexual transmission among...
Tue May 12, 2020 03:00
Viruses, Vol. 12, Pages 532: Green Bees: Reverse Genetic Analysis of Deformed Wing Virus Transmission, Replication, and Tropism Viruses doi: 10.3390/v12050532 Authors: Olesya N. Gusachenko Luke Woodford Katharin Balbirnie-Cumming Ewan M. Campbell Craig R. Christie Alan S. Bowman David J. Evans Environmental and agricultural pollination services by honey bees, Apis mellifera, and honey production are compromised by high levels of annual colony losses globally. The majority...
Tue May 12, 2020 03:00
Viruses, Vol. 12, Pages 531: Usutu Virus Infection of Embryonated Chicken Eggs and a Chicken Embryo-Derived Primary Cell Line Viruses doi: 10.3390/v12050531 Authors: Emna Benzarti José Rivas Michaël Sarlet Mathieu Franssen Nassim Moula Giovanni Savini Alessio Lorusso Daniel Desmecht Mutien-Marie Garigliany Usutu virus (USUV) is a mosquito-borne flavivirus, closely related to the West Nile virus (WNV). Similar to WNV, USUV may cause infections in humans, with occasional,...
Tue May 12, 2020 03:00
Viruses, Vol. 12, Pages 530: Detection of Astrovirus in a Cow with Neurological Signs by Nanopore Technology, Italy Viruses doi: 10.3390/v12050530 Authors: Guendalina Zaccaria Alessio Lorusso Melanie M. Hierweger Daniela Malatesta Sabrina VP Defourny Franco Ruggeri Cesare Cammà Pasquale Ricci Marco Di Domenico Antonio Rinaldi Nicola Decaro Nicola D’Alterio Antonio Petrini Torsten Seuberlich Maurilia Marcacci In this study, starting from nucleic...
Mon May 11, 2020 03:00
Viruses, Vol. 12, Pages 528: Eco-Epidemiological Evidence of the Transmission of Avian and Human Influenza A Viruses in Wild Pigs in Campeche, Mexico Viruses doi: 10.3390/v12050528 Authors: Maya-Badillo Ojeda-Flores Chaves Reveles-Félix Orta-Pineda Martínez-Mercado Saavedra-Montañez Segura-Velázquez Sanvicente Sánchez-Betancourt Influenza, a zoonosis caused by various influenza A virus subtypes, affects a wide range of species, including humans. Pig...
Mon May 11, 2020 03:00
Viruses, Vol. 12, Pages 529: Key Players in HIV-1 Transcriptional Regulation: Targets for a Functional Cure Viruses doi: 10.3390/v12050529 Authors: Luisa Mori Susana T. Valente HIV-1 establishes a life-long infection when proviral DNA integrates into the host genome. The provirus can then either actively transcribe RNA or enter a latent state, without viral production. The switch between these two states is governed in great part by the viral protein, Tat, which promotes RNA transcript...
Mon May 11, 2020 03:00
Viruses, Vol. 12, Pages 527: Prognostic Value of Cardiovascular Biomarkers in COVID-19: A Review Viruses doi: 10.3390/v12050527 Authors: Maryam Aboughdir Thomas Kirwin Ashiq Abdul Khader Brian Wang In early December 2019, the coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first emerged in Wuhan, China. As of May 10th, 2020, a total of over 4 million COVID-19 cases and 280,000 deaths have been reported globally, reflecting...
Mon May 11, 2020 03:00
Viruses, Vol. 12, Pages 526: SARS-CoV-2/COVID-19: Viral Genomics, Epidemiology, Vaccines, and Therapeutic Interventions Viruses doi: 10.3390/v12050526 Authors: Mohammed Uddin Farah Mustafa Tahir A. Rizvi Tom Loney Hanan Al Suwaidi Ahmed H. Hassan Al-Marzouqi Afaf Kamal Eldin Nabeel Alsabeeha Thomas E. Adrian Cesare Stefanini Norbert Nowotny Alawi Alsheikh-Ali Abiola C. Senok The COVID-19 pandemic is due to infection caused by the novel SARS-CoV-2 virus...
Sun May 10, 2020 03:00
Viruses, Vol. 12, Pages 525: Potential Drugs Targeting Early Innate Immune Evasion of SARS-Coronavirus 2 via 2’-O-Methylation of Viral RNA Viruses doi: 10.3390/v12050525 Authors: José Antonio Encinar Javier A. Menendez The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causing the COVID-19 respiratory disease pandemic utilizes unique 2′-O-methyltransferase (2′-O-MTase) capping machinery to camouflage its RNA from innate immune recognition. The nsp16...
Sun May 10, 2020 03:00
Viruses, Vol. 12, Pages 524: Glucose-Regulated Protein 78 Interacts with Zika Virus Envelope Protein and Contributes to a Productive Infection Viruses doi: 10.3390/v12050524 Authors: Jamie Royle Carolina Ramírez-Santana Snezhana Akpunarlieva Claire L. Donald Rommel J. Gestuveo Juan-Manuel Anaya Andres Merits Richard Burchmore Alain Kohl Margus Varjak Zika virus (ZIKV; Flaviviridae) is a mosquito-borne flavivirus shown to cause fetal abnormalities collectively...
Sat May 09, 2020 03:00
Viruses, Vol. 12, Pages 522: The T4 TerL Prohead Packaging Motor Does Not Drive DNA Translocation by a Proposed Dehydration Mechanism Viruses doi: 10.3390/v12050522 Authors: Lindsay W. Black Bingxue Yan Krishanu Ray A “DNA crunching” linear motor mechanism that employs a grip-and-release transient spring like compression of B- to A-form DNA has been found in our previous studies. Our FRET measurements in vitro show a decrease in distance from TerL to portal...
Sat May 09, 2020 03:00
Viruses, Vol. 12, Pages 523: Description of a Novel Mycovirus in the Phytopathogen Fusarium culmorum and a Related EVE in the Yeast Lipomyces starkeyi Viruses doi: 10.3390/v12050523 Authors: Mathieu Mahillon Gustavo Romay Charlotte Liénard Anne Legrève Claude Bragard A new mycovirus was found in the Fusarium culmorum strain A104-1 originally sampled on wheat in Belgium. This novel virus, for which the name Fusarium culmorum virus 1 (FcV1) is suggested, is phylogenetically...
Sat May 09, 2020 03:00
Viruses, Vol. 12, Pages 520: The Effects of Pre-Existing Antibodies on Live-Attenuated Viral Vaccines Viruses doi: 10.3390/v12050520 Authors: Darren Z. L. Mok Kuan Rong Chan Live-attenuated vaccines (LAVs) have achieved remarkable successes in controlling virus spread, as well as for other applications such as cancer immunotherapy. However, with rapid increases in international travel, globalization, geographic spread of viral vectors, and widespread use of vaccines, there is an increasing...
Fri May 08, 2020 03:00
Viruses, Vol. 12, Pages 518: Influenza Virus Like Particles (VLPs): Opportunities for H7N9 Vaccine Development Viruses doi: 10.3390/v12050518 Authors: Peter Pushko Irina Tretyakova In the midst of the ongoing COVID-19 coronavirus pandemic, influenza virus remains a major threat to public health due to its potential to cause epidemics and pandemics with significant human mortality. Cases of H7N9 human infections emerged in eastern China in 2013 and immediately raised pandemic concerns...
Fri May 08, 2020 03:00
Viruses, Vol. 12, Pages 519: TRiC/CCT Complex, a Binding Partner of NS1 Protein, Supports the Replication of Zika Virus in Both Mammalians and Mosquitoes Viruses doi: 10.3390/v12050519 Authors: Yuchen Wang Ryuta Uraki Jesse Hwang Erol Fikrig Mosquito-borne Zika virus (ZIKV) can cause congenital microcephaly and Guillain–Barré syndrome, among other symptoms. Specific treatments and vaccines for ZIKV are not currently available. To further understand the host...
Fri May 08, 2020 03:00
Viruses, Vol. 12, Pages 521: Innate Type 2 Responses to Respiratory Syncytial Virus Infection Viruses doi: 10.3390/v12050521 Authors: Allison E. Norlander R. Stokes Peebles Jr. Respiratory syncytial virus (RSV) is a common and contagious virus that results in acute respiratory tract infections in infants. In many cases, the symptoms of RSV remain mild, however, a subset of individuals develop severe RSV-associated bronchiolitis. As such, RSV is the chief cause of infant hospitalization...
Fri May 08, 2020 03:00
Viruses, Vol. 12, Pages 517: Recombinant Myxoma Virus Expressing Walleye Dermal Sarcoma Virus orfC Is Attenuated in Rabbits Viruses doi: 10.3390/v12050517 Authors: Laura V. Ashton Sandra L. Quackenbush Jake Castle Garin Wilson Jasmine McCoy Mariah Jordan Amy L. MacNeill The poxvirus, myxoma virus (MYXV) has shown efficacy as an oncolytic virus (OV) in some cancer models. However, MYXV replication within murine cancer models and spontaneous canine sarcomas is short-lived....
Fri May 08, 2020 03:00
Water, Vol. 12, Pages 1368: Erratum: Masselink, G.; Lazarus, E.D. Defining Coastal Resilience. Water 2019, 11, 2587 Water doi: 10.3390/w12051368 Authors: Gerd Masselink Eli D Lazarus The authors wish to make the following erratum to this paper [...]
Tue May 12, 2020 03:00
Water, Vol. 12, Pages 1372: Role of Cluster Validity Indices in Delineation of Precipitation Regions
Water, Vol. 12, Pages 1372: Role of Cluster Validity Indices in Delineation of Precipitation Regions Water doi: 10.3390/w12051372 Authors: Nikhil Bhatia Jency M. Sojan Slobodon Simonovic Roshan Srivastav The delineation of precipitation regions is to identify homogeneous zones in which the characteristics of the process are statistically similar. The regionalization process has three main components: (i) delineation of regions using clustering algorithms, (ii) determining the...
Tue May 12, 2020 03:00
Water, Vol. 12, Pages 1371: Exploring Spatiotemporal Relations Between Soil Moisture, Precipitation, and Streamflow for a Large Set of Watersheds Using Google Earth Engine Water doi: 10.3390/w12051371 Authors: Nazmus Sazib John Bolten Iliana Mladenova An understanding of streamflow variability and its response to changes in climate conditions is essential for water resource planning and management practices that will help to mitigate the impacts of extreme events such as floods...
Tue May 12, 2020 03:00
Water, Vol. 12, Pages 1369: A Multi-Scale Mapping Approach Based on a Deep Learning CNN Model for Reconstructing High-Resolution Urban DEMs Water doi: 10.3390/w12051369 Authors: Ling Jiang Yang Hu Xilin Xia Qiuhua Liang Andrea Soltoggio Syed Rezwan Kabir The scarcity of high-resolution urban digital elevation model (DEM) datasets, particularly in certain developing countries, has posed a challenge for many water-related applications such as flood risk management. A solution...
Tue May 12, 2020 03:00
Water, Vol. 12, Pages 1364: A Two-Stage LP-NLP Methodology for the Least-Cost Design and Operation of Water Distribution Systems Water doi: 10.3390/w12051364 Authors: Mengning Qiu Mashor Housh Avi Ostfeld This paper presents a two-stage method for simultaneous least-cost design and operation of looped water distribution systems (WDSs). After partitioning the network into a chord and spanning trees, in the first stage, a reformulated linear programming (LP) method is used to find...
Tue May 12, 2020 03:00
Water, Vol. 12, Pages 1370: Simulating Reservoir Induced Lhasa Streamflow Variability Using ArcSWAT Water doi: 10.3390/w12051370 Authors: Muhammad Yasir Tiesong Hu Samreen Abdul Hakeem Lhasa River Basin being the socio-economic hotspot of Qinghai-Tibetan Plateau is experiencing an increased hydropower capacity in the form of damming and reservoir construction. The Pangduo hydropower station, commenced in 2013, is one of these developments. Lhasa River discharge is analyzed for...
Tue May 12, 2020 03:00
Water, Vol. 12, Pages 1365: Implementing a Statewide Deficit Analysis for Inland Surface Waters According to the Water Framework Directive—An Exemplary Application on Phosphorus Pollution in Schleswig-Holstein (Northern Germany) Water doi: 10.3390/w12051365 Authors: Phuong Ta Björn Tetzlaff Michael Trepel Frank Wendland Deficit analysis—which principally deals with the question “how big are the gaps between current water status and good ecological status?”—has...
Tue May 12, 2020 03:00
Water, Vol. 12, Pages 1366: 10th Anniversary of Water Water doi: 10.3390/w12051366 Authors: Jeroen C. J. H. Aerts This Special Issue was set up to mark the 10th anniversary of Water. The contributions to this Special Issue of Water were carefully selected by the late Guest Editor Prof. Dr. Arjen Hoekstra. Arjen was devoted to conducting excellent science and was motivated to create this Special Issue to be something ‘special’. It was therefore dedicated to the publication...
Tue May 12, 2020 03:00
Water, Vol. 12, Pages 1363: Evaluating Maize Drought and Wet Stress in a Converted Japanese Paddy Field Using a SWAP Model Water doi: 10.3390/w12051363 Authors: Kosuke Hamada Hisayoshi Inoue Hidetoshi Mochizuki Mayuko Asakura Yuta Shimizu Takeshi Takemura Japanese government recommend farmers to cultivate upland crops in paddy fields (“converted fields”) to suppress the overproduction of rice. Converted fields are subject to excessively wet and dry...
Tue May 12, 2020 03:00
Water, Vol. 12, Pages 1367: The Influence of Design and Operational Factors on the Removal of Personal Care Products by Constructed Wetlands Water doi: 10.3390/w12051367 Authors: Huma Ilyas Eric D. van Hullebusch This research presents the correlation analysis of selected design and operational factors (depth, area, hydraulic and organic loading rate, and hydraulic retention time), and physicochemical parameters (pH, temperature, and dissolved oxygen) of constructed wetlands (CWs)...
Tue May 12, 2020 03:00
Water, Vol. 12, Pages 1361: Intermittent Water Supply Management, Household Adaptation, and Drinking Water Quality: A Comparative Study in Two Chinese Provinces Water doi: 10.3390/w12051361 Authors: Li Cohen Li Lv He Wang Zhang Intermittent water supply (IWS) is a relatively common phenomenon across the world as well as in rural and peri-urban areas across China, though there has been little IWS-focused research from China published to date. IWS consumers typically...
Tue May 12, 2020 03:00
Water, Vol. 12, Pages 1362: Recharge Estimation Using CMB and Environmental Isotopes in the Verlorenvlei Estuarine System, South Africa and Implications for Groundwater Sustainability in a Semi-Arid Agricultural Region Water doi: 10.3390/w12051362 Authors: Andrew Watson Anya Eilers Jodie A. Miller Groundwater recharge remains one of the most difficult hydrogeological variables to measure accurately, especially for semi-arid environments where the recharge flux is much smaller than...
Tue May 12, 2020 03:00
Water, Vol. 12, Pages 1360: Global Warming Impacts on Severe Drought Characteristics in Asia Monsoon Region Water doi: 10.3390/w12051360 Authors: Jeong-Bae Kim Jae-Min So Deg-Hyo Bae Climate change influences the changes in drought features. This study assesses the changes in severe drought characteristics over the Asian monsoon region responding to 1.5 and 2.0 °C of global average temperature increases above preindustrial levels. Based on the selected 5 global climate...
Tue May 12, 2020 03:00
Water, Vol. 12, Pages 1355: Impacts of River Engineering on River Channel Behaviour: Implications for Managing Downstream Flood Risk Water doi: 10.3390/w12051355 Authors: George Heritage Neil Entwistle Although knowledge of sediment transport has improved over the last 25 years, our understanding of bedload transfer and sediment delivery is still based on a limited set of observations or on models that make assumptions on hydraulic and sediment transport processes. This study utilises...
Mon May 11, 2020 03:00
Water, Vol. 12, Pages 1358: Multisource Groundwater Contamination under Data Scarcity: The Case Study of Six Municipalities in the Proximity of the Naameh Landfill, Lebanon Water doi: 10.3390/w12051358 Authors: Michele Citton Sofie Croonenberg Anwar El Shami Ghina Chammas Sammy Kayed Najat Aoun Saliba Majdi Abou Najm Hani Tamim Salah Zeineldine Maha Makki Mohamad Kalot Issam Lakkis Mahmoud Al-Hindi Lebanon is affected by a protracted environmental...
Mon May 11, 2020 03:00
Water, Vol. 12, Pages 1359: Influence of Flood Waves, Production Wells, and Precipitation on Shallow Groundwater Using a Linear Regression Model Approach Based on a Case Study of Mohács Island, Hungary Water doi: 10.3390/w12051359 Authors: András Hervai Éva Farics István Sisák Gábor Farkas János Kovács Dénes Lóczy Studying the relationship between river water and shallow groundwater (SGW) during flood events is a research topic receiving increasing attention for many reasons....
Mon May 11, 2020 03:00
Water, Vol. 12, Pages 1357: Sand Content Prediction in Urban WWTPs Using MARS Water doi: 10.3390/w12051357 Authors: Vanesa Mateo Pérez José Manuel Mesa Fernández Francisco Ortega Fernández Henar Morán Palacios The pre-treatment stage of wastewater treatment plants (WWTP), where most of the larger waste, including sand and fat, is removed, is of great importance for the performance and durability of these plants. This work develops a model that predicts the sand content that...
Mon May 11, 2020 03:00
Water, Vol. 12, Pages 1356: Assessing Groundwater Vulnerability: DRASTIC and DRASTIC-Like Methods: A Review Water doi: 10.3390/w12051356 Authors: Alina Barbulescu Groundwater vulnerability studies are sources of essential information for the management of water resources, aiming at the water quality preservation. Different methodologies for estimating the groundwater vulnerability, in general, or of the karst aquifer, in particular, are known. Among them, DRASTIC is one of the most popular...
Mon May 11, 2020 03:00
Water, Vol. 12, Pages 1354: Anthropogenic Impact on Tropical Perennial River in South India: Snapshot of Carbon Dynamics and Bacterial Community Composition Water doi: 10.3390/w12051354 Authors: Katrin Premke Gunasekaran Dharanivasan Kristin Steger Kai Nils Nitzsche Vijayan Jayavignesh Indumathi M Nambi Sundaram Seshadri Riverine systems play an important role in the global carbon cycle, and they are considered hotspots for bacterial activities such as organic matter...
Mon May 11, 2020 03:00
Water, Vol. 12, Pages 1351: From Building Dams to Fetching Water: Scales of Politicization in the Indus Basin Water doi: 10.3390/w12051351 Authors: Abdul Aijaz Majed Akhter Water flows through and informs the socio-spatial geography of the Indus waterscape in Pakistan in myriad ways. This paper argues that state-led water development has historically attempted to bypass political conflict by invoking techno-scientific authority to render water development as a purely techno-managerial...
Sun May 10, 2020 03:00
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