It’s been driving policy decisions since covid-19 emerged in late 2019, but what is the R number, and does it matter, asks Elisabeth MahaseWhat is the R number?The R number could refer to either the...
15h
The European Virus Archive (EVA) was created in 2008 with funding from the FP7-EU Infrastructure Programme, in response to the need for a coordinated and readily accessible collection of viruses that could be made available to academia, public health organisations and industry. Within three years, it developed from a consortium of nine European laboratories to encompass associated partners in Africa, Russia, China, Turkey, Germany and Italy. In 2014, the H2020 Research and Innovation Framework Programme...
15h
Inflammatory disorders of the CNS are frequently accompanied by synaptic loss, which is thought to involve phagocytic microglia and complement components. However, the mechanisms accounting for aberrant synaptic connectivity in the context of CD8; +; T cell-driven neuronal damage are poorly understood. Here, we profiled the neuronal translatome in a murine model of encephalitis caused by CD8; +; T cells targeting antigenic neurons. Neuronal STAT1 signaling and downstream CCL2 expression were essential...
15h
The Kryos Basin is a deep-sea hypersaline anoxic basin (DHAB) located in the Eastern Mediterranean Sea (34.98°N 22.04° E). It is fi lled with brine of re-dissolved Messinian evaporites and is nearly saturated with MgCl 2 -equivalents, which makes this habitat extremely challenging for life. The strong density difference between the anoxic brine and the overlying oxic Mediterranean seawater impedes mixing, giving rise to a narrow chemocline. Here, we investigate the microbial community structure and...
15h
Large-scale in silico screening of compounds contained in printing inks for food packaging materials
Providing sustainable and safe nutrition to the population is one of the main tasks of the modern food industry. While food packaging materials fulfill their invaluable protective role, certain substances can migrate from them into food. Switzerland is worldwide the only country, in which substances in printing inks for food packaging are regulated. Approx. 5000 substances are listed in Annex 10 of the Ordinance on Food Contact Materials FCM (SR 817.023. 21). Briefly, they were evaluated based on...
15h
Morbid obesity plays an increasingly important role in healthcare. Patients who are severely obese often suffer from a range of medical problems. One problem is obesity-related hypoventilation syndrome with its resulting hypercapnia. We report a case of a 33-year-old female patient who was in an extraordinarily bad medical state, with severe hypercapnia (pCO2 15.1 kPa), sepsis, acute anuric kidney failure and resulting acidosis (pH 6.96). Her body mass index was 84 kg/m2. Her chances of survival...
15h
Background: The Hippo pathway is a developmental pathway recently discovered in Drosophila melanogaster; in mammals it normally controls organ development and wound healing. Hippo signaling is deregulated in breast cancer (BC). MST1/2 and LATS1/2 kinases are the upstream molecular elements of Hippo signaling which phosphorylate and regulate the two effectors of Hippo signaling, YAP1 and TAZ cotranscriptional activators. The two molecular effectors of the Hippo pathway facilitate their activity through...
15h
About 80 per cent of stars in the Milky Way’s central bulge have relatively close encounters with another star, which can fling off any planets orbiting them
15h
2444 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: quality of care These pubmed results were generated on 2020/05/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
15h
Malignant mesothelioma (MM) and the immune matricial microenvironment (IMM). Hierarchical cluster analysis revealed two distinct clusters of patients with either low or high risk for death of MM. Collagen V, CD8+ T lymphocytes and tumour cellularity densities characterized high and low risk subgroups with impact on outcome. Abstract Objective Previous studies have reported a close relationship between malignant mesothelioma (MM) and the immune matricial microenvironment (IMM). One of the major...
15h
Analysis of the national SEER database revealed that lymph node status (ypN category) was an important prognostic factor, and supported the combination of ypT1 and ypT2 in grouping. Tumor grade ramained an independent predictor of survival in the setting of neoadjuvant therapy, and could improve the performance of ypTNM staging system. Abstract Background The evaluation of the eighth edition of ypTNM staging system for patients with esophageal cancer was limited in the setting of neoadjuvant...
15h
Abstract Purpose of review Herein, we summarize recent findings of novel lipid interactions between hosts and pathogens with the hope that further research is pursued in this emerging area of tropical disease lipidomics. Recent findings Hard-to-treat tropical diseases may be viral, parasitic, or bacterial in origin. Primarily caused in regions with high population...
15h
Abstract Purpose of review Until recently, human immunodeficiency virus (HIV) was considered a contraindication to solid organ transplant (SOT) as there were concerns about poor outcomes given the high degree of immunosuppression needed to successfully transplant and retain an allograft. Emerging data has shown positive outcomes in HIV-infected solid organ transplants but a less well-explored area in the literature is SOT in those co-infected...
15h
Publication date: Available online 12 May 2020Source: Journal of Infection and ChemotherapyAuthor(s): Noriko Takeuchi, Misako Ohkusu, Haruka Hishiki, Katsunori Fujii, Megumi Hotta, Shota Murata, Naruhiko Ishiwada
16h
Publication date: Available online 12 May 2020Source: Journal of Infection and ChemotherapyAuthor(s): K.S. Sreedeep, Sunil Sethi, Rakesh Yadav, Pankaj C. Vaidya, Suresh Kumar Angurana, Aastha Saini, Nancy Mehra, Meenu Singh
16h
Publication date: Available online 12 May 2020Source: Journal of Infection and ChemotherapyAuthor(s): Masami Nakazawa, Kanae Hara, Takuji Komeda, Eriko Ogura
16h
Publication date: August 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 135Author(s): Kara D. Meister
16h
Publication date: August 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 135Author(s): Shorook Na'ara, Waseem Sayegh, Waseem Nassar, Shadi Shinnawi, Ziv Gil, Arie Gordin
16h
Publication date: Available online 11 May 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Bryan K. Lao, Zeev N. Kain, Dina Khoury, Brooke N. Jenkins, Jeremy Prager, Robert S. Stevenson, Brenda Golianu, Jeannie Zuk, Jeffrey I. Gold, Qiu Zhong, Michelle A. Fortier
16h
Publication date: Available online 11 May 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Charlene Santoni, Michael Thaut, Tim Bressmann
16h
Prevalence of Prescription Medication Use in Preschool-age Children Seen in Pediatric Otolaryngology
Publication date: Available online 11 May 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Friederike S. Luetzenberg, Timothy M. Maul, Julie L. Wei
16h
Publication date: Available online 11 May 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Sercan CIKRIKCI, Huseyin DENİZ, Secaattin GULSEN
16h
Publication date: Available online 8 May 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Luca Verrecchia, Katarina Galle Barrett, Eva Karltorp
16h
Publication date: Available online 8 May 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Peiyu Du, Shimin Zong, Yingying Wen, Tianyi Liu, Yanji Qu, Hao Li, Wenting Yu, Enhao Wang, Yi Zhong, Hongjun Xiao
16h
Publication date: Available online 5 May 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Xiaoyu Wang, Manfei Zhang, Jianhui Han, Hao Wang, Song Li
16h
Publication date: Available online 5 May 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Asitha.D.L. Jayawardena, M. Shannon Fracchia, Bethany L. Bartley, Lael M. Yonker, Allen Lapey, Frank Virgin, Christopher J. Hartnick
16h
Speech perception with simultaneous bilateral cochlear implants: Is there a unilateral predominance?
Publication date: Available online 5 May 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Eman Hajr, Meshael AlFayez, Farid Alzhrani
16h
Publication date: Available online 5 May 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Giulia de Soccio, Vincenzo Savastano, Simone Minasi, Serena Bertin, Marta Serafini, Tommaso Vittori, Mara Riminucci, Alessandro Corsi
16h
Disease course of lung oligometastatic colorectal cancer treated with stereotactic body radiotherapy
Abstract Purpose Stereotactic body radiotherapy (SBRT) or stereotactic ablative radiotherapy (SABR) has been shown to increase survival rates in oligometastatic disease (OMD), but local control of colorectal metastases remains poor. We aimed to explore the natural course of oligometastatic colorectal cancer and to investigate how SBRT of lung metastases can delay the progression to polymetastatic disease (PMD). ...
16h
Abstract Background and objective The optimal management of prostate cancer (PC) recurrences after definitive or postoperative radiotherapy (RT) is still controversial. The aim of the present retrospective study was to report the preliminary clinical results and toxicity of a mono-institutional series of patients re-irradiated with linac-based SBRT in recurrent prostate cancer. ...
16h
Publication date: Available online 11 May 2020Source: GeneAuthor(s): Jian Yao, Chen Li, Lin Shi, Yuanan Lu, Xueqin Liu
16h
Publication date: Available online 11 May 2020Source: GeneAuthor(s): Parvin A Barbhuiya, Arif Uddin, Supriyo Chakraborty
16h
Antibiotics, Vol. 9, Pages 247: GC-MS Profile and Enhancement of Antibiotic Activity by the Essential Oil of Ocotea odorífera and Safrole: Inhibition of Staphylococcus aureus Efflux Pumps Antibiotics doi: 10.3390/antibiotics9050247 Authors: Almeida Freitas Araújo Menezes Santos Tintino Moura Filho Ferreira Silva Silva Amaral Deschamps Iriti Coutinho Considering the evidence that essential oils, as well as safrole,...
16h
Antibiotics, Vol. 9, Pages 246: A Retrospective Whole-Genome Sequencing Analysis of Carbapenem and Colistin-Resistant Klebsiella Pneumoniae Nosocomial Strains Isolated during an MDR Surveillance Program Antibiotics doi: 10.3390/antibiotics9050246 Authors: Bernardina Gentile Antonella Grottola Gabriella Orlando Giulia Fregni Serpini Claudia Venturelli Marianna Meschiari Anna Anselmo Silvia Fillo Antonella Fortunato Florigio Lista Monica Pecorari Cristina...
16h
Antibiotics, Vol. 9, Pages 245: Validation of a Worst-Case Scenario Method Adapted to the Healthcare Environment for Testing the Antibacterial Effect of Brass Surfaces and Implementation on Hospital Antibiotic-Resistant Strains Antibiotics doi: 10.3390/antibiotics9050245 Authors: Dauvergne Lacquemant Adjidé Mullié The evaluation of antibacterial activity of metal surfaces can be carried out using various published guidelines which do not always agree with each other...
16h
370 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: health technology These pubmed results were generated on 2020/05/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
16h
Publication date: Available online 11 May 2020Source: Translational ResearchAuthor(s): Leonard Naymagon
16h
Abstract Purpose Indicators to assess early liver damage and disease progression in nonalcoholic fatty liver disease (NAFLD) remain unsatisfactory. Albumin binding function has been reported to be an early indicator of liver damage in hepatitis and liver cirrhosis. However, its role in NAFLD patients is unknown. Methods An age/sex-matched, case-control...
16h
It’s been driving policy decisions since covid-19 emerged in late 2019, but what is the R number, and does it matter, asks Elisabeth MahaseWhat is the R number?The R number could refer to either the...
16h
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου