Microorganisms, Vol. 8, Pages 717: Production of Raw Starch-Digesting Amylolytic Preparation in Yarrowia lipolytica and Its Application in Biotechnological Synthesis of Lactic Acid and Ethanol Microorganisms doi: 10.3390/microorganisms8050717 Authors: Gęsicka Borkowska Białas Kaczmarek Celińska Sustainable economy drives increasing demand for raw biomass-decomposing enzymes. Microbial expression platforms exploited as cellular factories of such biocatalysts meet requirements...
Tue May 12, 2020 03:00
Microorganisms, Vol. 8, Pages 715: Organoids and Bioengineered Intestinal Models: Potential Solutions to the Cryptosporidium Culturing Dilemma Microorganisms doi: 10.3390/microorganisms8050715 Authors: Gunasekera Zahedi O’Dea King Monis Thierry Carr Ryan Cryptosporidium is a major cause of severe diarrhea-related disease in children in developing countries, but currently no vaccine or effective treatment exists for those who are most at risk of serious illness....
Mon May 11, 2020 03:00
Microorganisms, Vol. 8, Pages 711: Statistical Optimization of the Physico-Chemical Parameters for Pigment Production in Submerged Fermentation of Talaromyces albobiverticillius 30548 Microorganisms doi: 10.3390/microorganisms8050711 Authors: Venkatachalam Shum-Chéong-Sing Dufossé Fouillaud Talaromyces albobiverticillius 30548 is a marine-derived pigment producing filamentous fungus, isolated from the La Réunion island, in the Indian Ocean. The objective of this...
Mon May 11, 2020 03:00
Microorganisms, Vol. 8, Pages 714: Characteristics and Driving Factors of the Aerobic Denitrifying Microbial Community in Baiyangdian Lake, Xiong’an New Area Microorganisms doi: 10.3390/microorganisms8050714 Authors: Zhou Sun Li Huang Here, the ion-exchangeable form of nitrogen (IEF-N), weak-acid extractable form of nitrogen (WAEF-N), strong-alkali extractable form of nitrogen (SAEF-N), strong-oxidant extractable form of nitrogen (SOEF-N), residue nitrogen (Res-N), and total...
Mon May 11, 2020 03:00
Microorganisms, Vol. 8, Pages 713: Systematic Review of the Respiratory Syncytial Virus (RSV) Prevalence, Genotype Distribution, and Seasonality in Children from the Middle East and North Africa (MENA) Region Microorganisms doi: 10.3390/microorganisms8050713 Authors: Yassine Sohail Younes Nasrallah Respiratory syncytial virus (RSV) is one of the most common viruses to infect children worldwide and is the leading cause of lower respiratory tract illness (LRI) in infants....
Mon May 11, 2020 03:00
Microorganisms, Vol. 8, Pages 710: Elicitation of Cluster A and Co-Receptor Binding Site Antibodies are Required to Eliminate HIV-1 Infected Cells Microorganisms doi: 10.3390/microorganisms8050710 Authors: Guillaume Beaudoin-Bussières Jérémie Prévost Gabrielle Gendron-Lepage Bruno Melillo Junhua Chen Amos B. Smith III Marzena Pazgier Andrés Finzi HIV-1-infected individuals raise a polyclonal antibody response targeting multiple envelope glycoprotein (Env) epitopes....
Mon May 11, 2020 03:00
Microorganisms, Vol. 8, Pages 712: Diversity of Glutathione S-Transferases (GSTs) in Cyanobacteria with Reference to Their Structures, Substrate Recognition and Catalytic Functions Microorganisms doi: 10.3390/microorganisms8050712 Authors: ShylajaNaciyar Karthick Prakasam Deviram Uma Prabaharan Saha Glutathione S-Transferases (GSTs) comprise a diverse group of protein superfamily involved in cellular detoxification of various harmful xenobiotics and endobiotics....
Mon May 11, 2020 03:00
Microorganisms, Vol. 8, Pages 706: Transcriptional Regulation of the Outer Membrane Protein A in Acinetobacter baumannii Microorganisms doi: 10.3390/microorganisms8050706 Authors: Kyu-Wan Oh Kyeongmin Kim Md. Maidul Islam Hye-Won Jung Daejin Lim Je Chul Lee Minsang Shin Acinetobacter baumannii is known for its virulence in severely ill, hospitalized patients and for exhibiting multidrug resistance. A. baumannii infection treatment poses a serious problem in clinical...
Mon May 11, 2020 03:00
Microorganisms, Vol. 8, Pages 708: Occurrence of blaTEM and blaCTXM Genes and Biofilm-Forming Ability among Clinical Isolates of Pseudomonas aeruginosa and Acinetobacter baumannii in Yaoundé, Cameroon Microorganisms doi: 10.3390/microorganisms8050708 Authors: Madaha Gonsu Bughe Fonkoua Ateba Mbacham Background: Pseudomonas aeruginosa (PSA) and Acinetobacter baumannii (ACB) are non-fermentative bacteria mostly associated with nosocomial infections in humans. Objective:...
Mon May 11, 2020 03:00
Microorganisms, Vol. 8, Pages 709: Assessment of the Immunomodulatory Properties of the Probiotic Strain Lactobacillus paracasei K5 in vitro and In Vivo Microorganisms doi: 10.3390/microorganisms8050709 Authors: Chondrou Karapetsas Kiousi Vasileiadis Ypsilantis Botaitis Alexopoulos Plessas Bezirtzoglou Galanis Lactobacillus paracasei K5 is a lactic acid bacteria (LAB) strain that has been isolated from dairy products. Previous studies have established...
Mon May 11, 2020 03:00
Microorganisms, Vol. 8, Pages 707: Transcriptome Analysis of Gene Expression in Dermacoccus abyssi HZAU 226 under Lysozyme Stress Microorganisms doi: 10.3390/microorganisms8050707 Authors: Zhang Ruan Liu Chen Gu Guo Lysozyme acts as a kind of cationic antimicrobial protein and effectively hydrolyzes bacterial peptidoglycan to have a bactericidal effect, which also plays an important role in protecting eggs from microbial contamination. Dermacoccus abyssi HZAU 226,...
Mon May 11, 2020 03:00
Microorganisms, Vol. 8, Pages 705: Biofilm Mode of Cultivation Leads to an Improvement of the Entomotoxic Patterns of Two Aspergillus Species Microorganisms doi: 10.3390/microorganisms8050705 Authors: Frédéric Francis Florent Druart José Diana Di Mavungu Marthe De Boevre Sarah De Saeger Frank Delvigne Two fungi, i.e., Aspergillus flavus Link and Aspergillus oryzae (Ahlb.) E. Cohn, were cultivated according to two methodologies, namely submerged and biofilm cultures with...
Mon May 11, 2020 03:00
Microorganisms, Vol. 8, Pages 704: Effects of Atmospheric Plasma Corona Discharges on Soil Bacteria Viability Microorganisms doi: 10.3390/microorganisms8050704 Authors: Yulia Lazra Irina Dubrovin Victor Multanen Edward Bormashenko Yelena Bormashenko Rivka Cahan Crop contamination by soil-borne pathogenic microorganisms often leads to serious infection outbreaks. Plant protection requires disinfection of agricultural lands. The chemical and the physical disinfection procedures...
Mon May 11, 2020 03:00
Molbank, Vol. 2020, Article M1134: Synthesis and Spectral Characterization of 4,7-Dichloro-6-nitroquinazoline Molbank doi: 10.3390/M1134 Authors: Thi Ngoc Nguyen Thi Huong Tran Nguyet Suong Huyen Dao Van Giang Nguyen Dinh Luyen Nguyen Nguyen Trieu Trinh Van Hai Nguyen Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor (TKI) in the form of a dimaleate salt which is indicated for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC)....
Mon May 11, 2020 03:00
Molbank, Vol. 2020, Article M1133: Formation of an Isomeric Mixture of Dienynes Instead of a Diallene Molbank doi: 10.3390/M1133 Authors: Susanne M. Petrova Leiv K. Sydnes Attempts to convert 1,1,2,2,7,7,8,8-octaethoxyocta-3,5-diyne to a symmetric allene by reduction with lithium aluminum hydride failed. Instead reduction accompanied by isomerization occurred and afforded 1,1,2,7,8,8-hexaethoxyocta-2,6-dien-4-yne as a mixture of three isomers in 63% total isolated yield.
Mon May 11, 2020 03:00
Molecules, Vol. 25, Pages 2282: The Influence of Various N-Heterocyclic Carbene Ligands on Activity of Nitro-Activated Olefin Metathesis Catalysts Molecules doi: 10.3390/molecules25102282 Authors: Michał Pieczykolan Justyna Czaban-Jóźwiak Maura Malinska Krzysztof Woźniak Reto Dorta Anna Rybicka Anna Kajetanowicz Karol Grela A set of nitro-activated ruthenium-based Hoveyda-Grubbs type olefin metathesis catalysts bearing sterically modified N-hetero-cyclic carbene...
Tue May 12, 2020 03:00
Molecules, Vol. 25, Pages 2280: Trinuclear NiII-LnIII-NiII Complexes with Schiff Base Ligands: Synthesis, Structure, and Magnetic Properties Molecules doi: 10.3390/molecules25102280 Authors: Anastasia N. Georgopoulou Michael Pissas Vassilis Psycharis Yiannis Sanakis Catherine P. Raptopoulou The reaction of the Schiff base ligand o-OH-C6H4-CH=N-C(CH2OH)3, H4L, with Ni(O2CMe)2∙4H2O and lanthanide nitrate salts in a 4 : 2 : 1 ratio lead to the formation of the trinuclear complexes...
Tue May 12, 2020 03:00
Molecules, Vol. 25, Pages 2281: Virtual Screening and the In Vitro Assessment of the Antileishmanial Activity of Lignans Molecules doi: 10.3390/molecules25102281 Authors: Mayara dos Santos Maia Joanda Paolla Raimundo e Silva Thaís Amanda de Lima Nunes Julyanne Maria Saraiva de Sousa Gabriela Cristina Soares Rodrigues Alex France Messias Monteiro Josean Fechine Tavares Klinger Antonio da Franca Rodrigues Francisco Jaime B. Mendonça-Junior Luciana Scotti Marcus...
Tue May 12, 2020 03:00
Molecules, Vol. 25, Pages 2278: Therapeutic Emergence of Rhein as a Potential Anticancer Drug: A Review of Its Molecular Targets and Anticancer Properties Molecules doi: 10.3390/molecules25102278 Authors: Sahu Henamayee Kishore Banik Bethsebie Lalduhsaki Sailo Bano Shabnam Choudhary Harsha Satti Srilakshmi Naidu VGM Seung Ho Baek Kwang Seok Ahn Ajaikumar B Kunnumakkara According to the World Health Organization (WHO), cancer is the second-highest cause of mortality...
Tue May 12, 2020 03:00
Molecules, Vol. 25, Pages 2277: Lipoteichoic Acid Biosynthesis Inhibitors as Potent Inhibitors of S. aureus and E. faecalis Growth and Biofilm Formation Molecules doi: 10.3390/molecules25102277 Authors: George A. Naclerio Kenneth I. Onyedibe Herman O. Sintim Methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecalis (VRE) have been deemed as serious threats by the CDC. Many chronic MRSA and VRE infections are due to biofilm formation. Biofilm...
Tue May 12, 2020 03:00
Molecules, Vol. 25, Pages 2279: The Effect of Carbon Black on the Properties of Plasticised Wheat Gluten Biopolymer Molecules doi: 10.3390/molecules25102279 Authors: Oisik Das Antonio J Capezza Julia Mårtensson Yu Dong Rasoul Esmaeely Neisiany Leonardo Pelcastre Lin Jiang Qiang Xu Richard T. Olsson Mikael S Hedenqvist Wheat gluten biopolymers generally become excessively rigid when processed without plasticisers, while the use of plasticisers, on the other...
Tue May 12, 2020 03:00
Molecules, Vol. 25, Pages 2274: Monitoring the Reactivity of Formamide on Amorphous SiO2 by In-Situ UV-Raman Spectroscopy and DFT Modeling Molecules doi: 10.3390/molecules25102274 Authors: Matteo Signorile Stefano Pantaleone Nadia Balucani Francesca Bonino Gianmario Martra Piero Ugliengo Formamide has been recognized in the literature as a key species in the formation of the complex molecules of life, such as nucleobases. Furthermore, several studies reported the impact...
Tue May 12, 2020 03:00
Molecules, Vol. 25, Pages 2276: Experimental Study of Pyrolysis and Laser Ignition of Low-Vulnerability Propellants Based on RDX Molecules doi: 10.3390/molecules25102276 Authors: Jordan Ehrhardt Léo Courty Philippe Gillard Barbara Baschung Low-vulnerability propellants are propellants designed to resist unintended stimuli to increase safety during transport, storage and handling. The substitution of usual nitrocellulose-based gun propellants with these new materials allows maintaining...
Tue May 12, 2020 03:00
Molecules, Vol. 25, Pages 2273: Chemical Kinetic Model of Multicomponent Gasoline Surrogate Fuel with Nitric Oxide in HCCI Combustion Molecules doi: 10.3390/molecules25102273 Authors: Chao Yang Zhaolei Zheng This study presents a simplified mechanism of a five-component gasoline surrogate fuel (TDRF–NO) that includes n-heptane, isooctane, toluene, diisobutylene (DIB) and nitric oxide (NO). The mechanism consists of 119 species and 266 reactions and involves TDRF and NO submechanisms....
Tue May 12, 2020 03:00
Molecules, Vol. 25, Pages 2272: Chiral Phase Transfer Catalysis in the Asymmetric Synthesis of a 3,3-Disubstituted Isoindolinone and Determination of Its Absolute Configuration by VCD Spectroscopy Molecules doi: 10.3390/molecules25102272 Authors: Guglielmo Monaco Maximilian Tiffner Antonia Di Mola Wouter Herrebout Mario Waser Antonio Massa In this work we report our endeavors toward the development of an asymmetric synthesis of a 3,3-disubstituted isoindolinone, dimethyl...
Tue May 12, 2020 03:00
Molecules, Vol. 25, Pages 2275: Experimental Comparative Study of Dynamic Behavior in Solution Phase of C-Tetra(phenyl)resorcin[4]arene and C-Tetra(phenyl)pyrogallol[4]arene Molecules doi: 10.3390/molecules25102275 Authors: José Luis Casas-Hinestroza Miguel Ángel Vela Suazo Mauricio Maldonado Villamil The synthesis of phenyl-resorcinarenes and pyrogallolarenes is known to produce a conformational mixture of cone and chair isomers. Depending on the synthesis conditions the composition...
Tue May 12, 2020 03:00
Molecules, Vol. 25, Pages 2271: Virtual Screening of Natural Products against Type II Transmembrane Serine Protease (TMPRSS2), the Priming Agent of Coronavirus 2 (SARS-CoV-2) Molecules doi: 10.3390/molecules25102271 Authors: Noor Rahman Zarrin Basharat Muhammad Yousuf Giuseppe Castaldo Luca Rastrelli Haroon Khan Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused about 2 million infections and is responsible for more than 100,000 deaths worldwide. To...
Tue May 12, 2020 03:00
Molecules, Vol. 25, Pages 2270: Recent Advances in Polymer Nanomaterials for Drug Delivery of Adjuvants in Colorectal Cancer Treatment: A Scientific-Technological Analysis and Review Molecules doi: 10.3390/molecules25102270 Authors: Marlon Osorio Estefanía Martinez Tonny Naranjo Cristina Castro Colorectal cancer (CRC) is the type with the second highest morbidity. Recently, a great number of bioactive compounds and encapsulation techniques have been developed. Thus, this paper...
Tue May 12, 2020 03:00
Molecules, Vol. 25, Pages 2269: Crystal Structure of a Tetrameric Type II β-Carbonic Anhydrase from the Pathogenic Bacterium Burkholderia pseudomallei Molecules doi: 10.3390/molecules25102269 Authors: Andrea Angeli Marta Ferraroni Mariana Pinteala Stelian S. Maier Bogdan C. Simionescu Fabrizio Carta Sonia Del Prete Clemente Capasso Claudiu T. Supuran Carbonic anhydrase (CA) is a zinc enzyme that catalyzes the reversible conversion of carbon dioxide to bicarbonate...
Tue May 12, 2020 03:00
Molecules, Vol. 25, Pages 2268: N-Alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides and Their Analogues: Synthesis and Multitarget Biological Activity Molecules doi: 10.3390/molecules25102268 Authors: Martin Krátký Zsuzsa Baranyai Šárka Štěpánková Katarína Svrčková Markéta Švarcová Jiřina Stolaříková Lilla Horváth Szilvia Bősze Jarmila Vinšová Based on the isosterism concept, we have designed and synthesized homologous N-alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides...
Tue May 12, 2020 03:00
Molecules, Vol. 25, Pages 2267: Plasmon-Enhanced Controlled Drug Release from Ag-PMA Capsules Molecules doi: 10.3390/molecules25092267 Authors: Giulia Neri Carmelo Corsaro Enza Fazio Silver (Ag)-grafted PMA (poly-methacrylic acid, sodium salt) nanocomposite loaded with sorafenib tosylate (SFT), an anticancer drug, showed good capability as a drug carrier allowing on-demand control of the dose, timing and duration of the drug release by laser irradiation stimuli. In this study,...
Mon May 11, 2020 03:00
Molecules, Vol. 25, Pages 2265: Predicting Drug Resistance Using Deep Mutational Scanning Molecules doi: 10.3390/molecules25092265 Authors: Gur Pines Reilly G. Fankhauser Carrie A. Eckert Drug resistance is a major healthcare challenge, resulting in a continuous need to develop new inhibitors. The development of these inhibitors requires an understanding of the mechanisms of resistance for a critical mass of occurrences. Recent genome editing technologies based on high-throughput...
Mon May 11, 2020 03:00
Molecules, Vol. 25, Pages 2266: Multivariate Analysis of Photoacoustic Spectra for the Detection of Short-Chained Hydrocarbon Isotopologues Molecules doi: 10.3390/molecules25092266 Authors: Alain Loh Marcus Wolff We report, to our knowledge, the first optical detection scheme for short-chained hydrocarbon isotopologues. The sensor system is based on photoacoustic spectroscopy (PAS). Two continuous wave, thermoelectrically cooled, distributed feedback interband cascade lasers (DFB-ICLs)...
Mon May 11, 2020 03:00
Molecules, Vol. 25, Pages 2263: The Influence of Powder Milling on Properties of SPS Compacted FeAl Molecules doi: 10.3390/molecules25092263 Authors: Alena Michalcová Murat Özkan Pavol Mikula Ivo Marek Anna Knaislová Jaromír Kopeček Dalibor Vojtěch The Fe-28 at.% Al alloy was studied in this article. The aim was to describe the influence of gas atomized powder pre-milling before SPS (Spark Plasma Sintering) sintering on the structure and properties of the bulk materials....
Mon May 11, 2020 03:00
Molecules, Vol. 25, Pages 2256: Surface Modification of Magnetic Nanoparticles by Carbon-Coating Can Increase Its Biosafety: Evidences from Biochemical and Neurobehavioral Tests in Zebrafish Molecules doi: 10.3390/molecules25092256 Authors: Nemi Malhotra Gilbert Audira Jung-Ren Chen Petrus Siregar Hua-Shu Hsu Jiann-Shing Lee Tzong-Rong Ger Chung-Der Hsiao Recently, magnetic nanoparticles (MNPs) have gained much attention in the field of biomedical engineering for...
Mon May 11, 2020 03:00
Molecules, Vol. 25, Pages 2262: Panax quinquefolium L. Ginsenosides from Hairy Root Cultures and Their Clones Exert Cytotoxic, Genotoxic and Pro-Apoptotic Activity towards Human Colon Adenocarcinoma Cell Line Caco-2 Molecules doi: 10.3390/molecules25092262 Authors: Ewa Kochan Adriana Nowak Małgorzata Zakłos-Szyda Daria Szczuka Grażyna Szymańska Ilona Motyl American ginseng, Panax quinquefolium (L.), is traditionally used in folk medicine. It exhibits a range of anti-inflammatory,...
Mon May 11, 2020 03:00
Molecules, Vol. 25, Pages 2264: Surface Interactions during the Removal of Emerging Contaminants by Hydrochar-Based Adsorbents Molecules doi: 10.3390/molecules25092264 Authors: Silvia Román Joâo Manuel Valente Nabais Beatriz Ledesma Carlos Laginhas Maria-Magdalena Titirici The aim of this work was to test activated carbons derived from hydrochars produced from sunflower stem, olive stone and walnut shells, as adsorbents for emerging contaminants in aqueous solution, namely...
Mon May 11, 2020 03:00
Molecules, Vol. 25, Pages 2261: Identification of Aroma Differences in Refined and Whole Grain Extruded Maize Puffs Molecules doi: 10.3390/molecules25092261 Authors: Kenneth Smith Devin G. Peterson Differences in the aroma profiles of extruded maize puffs made from refined grain and whole grain flour were investigated. Gas chromatography/mass spectrometry/olfactometry (GC/MS/O) analysis reported 13 aroma compounds with a flavor dilution (FD) value ≥16. Quantitative analysis...
Mon May 11, 2020 03:00
Molecules, Vol. 25, Pages 2259: Fabrication of High-Performance Bamboo–Plastic Composites Reinforced by Natural Halloysite Nanotubes Molecules doi: 10.3390/molecules25092259 Authors: Xiaobei Jin Jingpeng Li Rong Zhang Zehui Jiang Daochun Qin Bamboo-plastic composites (BPCs) as new biomass-plastic composites have recently attracted much attention. However, weak mechanical performance and high moisture absorption as well as low thermal stability greatly limit their industrial...
Mon May 11, 2020 03:00
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