Motivational climate in exercise group environments would have an impact on adherence, effort and enjoyment. We examined the motivational climate among nursing home residents who were involved in group exercis...
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To analyze the influence of socioeconomic determinants on the development of overweight and obesity in the mother-child binomial.
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Abstract Background High-risk HPV is a causative factor of cervical cancer. HPV DNA fragments integrate into host genome resulting in the constitutive expression of HPV genes E6 and E7 under the regulation of transcription factors, such as p300 and Tip60. Interestingly, Tip60, a factor with HAT (histone acetyl transferase) activity, represses HPV18 E6/E7 genes while another HAT p300 activates the transcription of HPV18 E6/E7. ...
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Abstract The poultry industry in the European Union produces 13 million tons of manure annually, which represents a major health and environmental challenge. Composting is an environmental-friendly technique for the management of manure, but there are few studies about antibiotic residues and antimicrobial resistances at a field scale. The goal of this study was to determine if the composting of poultry manure at a field scale would result in the reduction of antibiotic residues,...
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Abstract The development of efficient solar driven catalyst for the degradation of antibiotics has become increasingly important in environmental protection. However, the reported efficient photocatalysts for antibiotic degradation are limited. In this work, porous Fe3+-doped graphitic carbon nitride (g-C3N4) with outstanding photocatalytic ability is synthesized and then used as the photocatalyst for the efficient degradation of sulfadiazine (SDZ) under visible light. A series...
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Abstract Bio-evaluating of surface waters is not a new approach but is becoming more important since the application of the European Water Framework Directive (WFD). The present study was designed to evaluate the limno-ecological conditions of rivers in the West Mediterranean basin of Turkey using diatom metrics and multivariate approaches according to the WFD requirements. Canonical correspondence analysis (CCA) was used to assess the relationships of diatom species and environmental...
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The US currently carries the ignoble distinction of being the world leader in both incarceration and prevalence of covid-19. Worse still, around 12% of the 2.3 million people currently in state and...
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The moral fortitude of clinicians and health systems has been tested as the number of patients with covid-19 has grown. Experts initially warned that patients requiring ventilatory support could...
16h
What you need to knowInterpreting the result of a test for covid-19 depends on two things: the accuracy of the test, and the pre-test probability or estimated risk of disease before testingA positive...
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Stay alert for what?Covid-19, of course. In a curious move, Boris Johnson’s UK government has decided to ditch its clear, unambiguous public information slogan of “stay home, protect the NHS, save...
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Men working in the lowest skilled jobs had the highest rate of death involving covid-19 among working age people, the latest figures from the Office for National Statistics (ONS) show.1However,...
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Prepare as if you were meeting in personRachel Heard, specialty trainee year 5 in general surgery, Northwest, says, “Breaking bad news is a challenging part of being a doctor. Many people use a...
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Related ArticlesOn the Work of Alexander of Tralles. Acta Med Hist Adriat. 2019 12;17(2):295-304 Authors: Panagiota K, Dimitrios F Abstract Helminthiasis is known to man since antiquity, but it still remains a significant public health problem. In ancient times many plants have been tried as possible therapeutics in search of an effective drug. This manuscript investigates ancient beliefs on parasitic worm infestation. Moreover, Alexander of Tralles'...
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Abstract Background Pediatric nuclear medicine is evolving, and its practice patterns are uncertain. Knowledge of the current trends in pediatric nuclear medicine might be helpful to direct local decisions, including expectations for patient care, needs for capital acquisitions, and staffing recruitment strategies. Objective To provide data regarding the...
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Abstract Relapse‐enriched somatic variants drive drug resistance in childhood acute lymphoblastic leukemia. We used digital droplet‐based polymerase chain reaction to establish whether relapse‐enriched mutations in emerging subclones could be detected in peripheral blood samples before frank relapse. Although limitations in sensitivity for some probes hindered detection of certain variants, we successfully detected variants in NT5C2 and PRPS1 at a fractional abundance of 0.005% to 0.3%, 41 to 116...
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Abstract Background The WHO Global Initiative for Childhood Cancer aims to increase survival to at least 60% for all children with cancer globally, with initial focus on six common curable cancer types. Frequent causes of treatment failure in low income countries (LICs) are treatment abandonment and death during treatment. Here, we report on the outcome at the end of treatment of patients with newly diagnosed common and curable cancer types, admitted in the Queen Elizabeth Central Hospital, Blantyre,...
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Abstract Hereditary hemolytic anemias (HHA) are a heterogeneous group of anemias associated with decreased red cell survival. While there can be clinical benefit of splenectomy in many cases, splenectomy is not appropriate for all types of HHA. Additionally, there are significant risks during and following splenectomy including surgical risks, postsplenectomy sepsis, and thrombotic complications. This review discusses the diagnostic approach to HHA as well as the role of splenectomy in the management....
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Abstract Introduction Our objectives were to design and validate methods to identify relapse and hematopoietic stem cell transplantation (HSCT) in children with acute lymphoblastic leukemia (ALL) using administrative data representing hospitalizations at US pediatric institutions. Methods We developed daily billing and ICD‐9 code definitions to identify relapses and HSCTs within a cohort of children with newly diagnosed ALL between January 1, 2004, and December 31, 2013, previously assembled...
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Abstract Background Acinic cell carcinoma (AciCC) is rare in children; therefore, reaching a consensus on its management is challenging and radiotherapy is limited by concerns about long‐term toxicity. The purpose of this study is to analyze the effectiveness and safety of surgery plus postoperative 125I interstitial brachytherapy (IBT) for children and adolescents with AciCC of the parotid gland (PG) treated at a single institution. Procedure Sixteen patients ≤ 18 years old with AciCC...
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Abstract Introduction The Collaborative Wilms Tumour (WT) Africa Project implemented an adapted WT treatment guideline in six centres in sub‐Saharan Africa. The primary objectives were to describe abandonment of treatment, death during treatment, event‐free survival (EFS) and relapse following implementation. An exploratory objective was to compare outcomes with the baseline evaluation, a historical cohort preceding implementation. Methods The Collaborative WT Africa Project is a multi‐centre...
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Abstract Oncologists and cancer biologists are frequently confronted by the question of what causes cancer? This is particularly vexing for cancers affecting children and young adults who have had limited exposure to environmental mutagens and the effects of aging. Here, I focus on a general framework of the causes of early‐onset cancer development in children and young adults by relating inherited and constitutional cancer predisposition, oncogenic pathogens, and developmental mutations. This framework...
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Abstract Supervised learning by means of Genetic Programming (GP) aims at the evolutionary synthesis of a model that achieves a balance between approximating the target function on the training data and generalising on new data. The model space searched by the Evolutionary Algorithm is populated by compositions of primitive functions defined in a function set. Since the target function is unknown, the choice of function set’s constituent elements is primarily guided by the makeup...
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2444 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: quality of care These pubmed results were generated on 2020/05/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Background: Several studies have linked acetaminophen exposure to the risk of allergic rhinitis, with controversial results. Methods: A systematic search of PubMed, Embase, Cochrane Library, and Web of Science was conducted up to December 1, 2019. We included observational studies that examined the association between acetaminophen exposure and the risk of allergic rhinitis. Two reviewers independently extracted data and assessed study quality. Summary odds ratios (ORs) and 95% confidence intervals...
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Cancers, Vol. 12, Pages 1211: Neuroendocrine Carcinoma of the Uterine Cervix: A Clinicopathologic and Immunohistochemical Study with Focus on Novel Markers (Sst2–Sst5) Cancers doi: 10.3390/cancers12051211 Authors: Inzani Santoro Angelico Feraco Spadola Arciuolo Valente Carlino Piermattei Scaglione Scambia Rindi Zannoni Background. Gynecological neuroendocrine neoplasms (NENs) are extremely rare, accounting for 1.2–2.4%...
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Cancers, Vol. 12, Pages 1212: Classification of Breast Cancer Cells Using the Integration of High-Frequency Single-Beam Acoustic Tweezers and Convolutional Neural Networks Cancers doi: 10.3390/cancers12051212 Authors: Hae Gyun Lim O-Joun Lee K. Kirk Shung Jin-Taek Kim Hyung Ham Kim Single-beam acoustic tweezers (SBAT) is a widely used trapping technique to manipulate microscopic particles or cells. Recently, the characterization of a single cancer cell using high-frequency...
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Introduction: Recent studies have reported that elevated levels of platelets and inflammatory markers are associated with poor treatment outcomes among patients with solid tumours, but reports are conflicting in head and neck cancer (HNC) patients. Objective: To establish if pre-treatment anti-inflammatory markers can be used as a prognostic tool of overall survival and tumour control among HNC patients. Methods: We retrospectively reviewed the pre-treatment platelet/lymphocyte ratio (PLR) and neutrophil/lymphocyte...
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Related ArticlesHead and neck cancer cannot wait for this pandemic to end: Risks, challenges and perspectives of oral-maxillofacial surgeon during COVID-19. Oral Oncol. 2020 May 01;:104758 Authors: Valentini V, Pucci R, Battisti A, Cassoni A PMID: 32389540 [PubMed - as supplied by publisher]
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Related ArticlesRegarding the concurrent presence of secretory carcinoma and Warthin's tumor in the ipsilateral parotid gland. Oral Oncol. 2020 May 07;:104763 Authors: Tretiakow D, Stodulski D, Skorek A PMID: 32389539 [PubMed - as supplied by publisher]
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Related ArticlesSurgical tracheostomies in COVID-19 patients: A multidisciplinary approach and lessons learned. Oral Oncol. 2020 May 03;:104767 Authors: Broderick D, Kyzas P, Baldwin AJ, Graham RM, Duncan T, Chaintoutis C, Boultoukas E, Vassiliou L Abstract Surgical tracheostomies have a role in the weaning process of COVID-19 patients treated in intensive care units. A multidisciplinary team approach (MDT) is required for decision making. This process...
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The US currently carries the ignoble distinction of being the world leader in both incarceration and prevalence of covid-19. Worse still, around 12% of the 2.3 million people currently in state and...
18h
The moral fortitude of clinicians and health systems has been tested as the number of patients with covid-19 has grown. Experts initially warned that patients requiring ventilatory support could...
18h
What you need to knowInterpreting the result of a test for covid-19 depends on two things: the accuracy of the test, and the pre-test probability or estimated risk of disease before testingA positive...
18h
The cover image is based on the Original Article A personalized computational model predicts cancer risk level of oral potentially malignant disorders and its web application for promotion of non‐invasive screening by Xiangjian Wang et al., https://doi.org/10.1111/jop.12983.
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Up to one in three of older patients who are hospitalised develop functional decline, which is associated with sustained disability, institutionalisation and death. This study developed and validated a clinical prediction model that identifies patients who are at risk for functional decline during hospitalisation. The predictive value of the model was compared against three models that were developed for patients admitted to a general medical ward.; A prospective cohort study was performed on two...
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Als Teilprojekt der nationalen Demenzstrategie der Schweiz wurde untersucht, inwieweit die in den Alters- und Pflegeheimen bereits eingesetzten Bedarfsabklärungsinstrumente BESA und RAI ausreichend sind, um Symptome von Depressionen, Delirien und behavioralen und psychologischen Symptomen der Demenz (BPSD) frühzeitig zu erkennen. Während RAI für die Bewertung von Depressivität als ausreichend aufgefasst wurde, ist für BESA die Ergänzung um den Zwei-Fragen-Test und die geriatrische Depressionsskala...
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DNA has been widely used as a key tether to promote self-organization of super-assemblies with emergent properties. However, control of this process is still challenging for compartment assemblies and to date the resulting assemblies have unstable membranes precluding in vitro and in vivo testing. Here we present our approach to overcome these limitations, by manipulating molecular factors such as compartment membrane composition and DNA surface density, thereby controlling the size and stability...
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