JCM, Vol. 9, Pages 1511: Medication Management after Bariatric Surgery: Providing Optimal Patient Care Journal of Clinical Medicine doi: 10.3390/jcm9051511 Authors: Daniel Porat Arik Dahan Substantially altered gastrointestinal anatomy/physiology after bariatric surgery presents new challenges for the proper medication management of these patients; drug absorption and bioavailability may increase, decrease, or remain unchanged post surgery, depending on the specific drug in question...
Sun May 17, 2020 03:00
JCM, Vol. 9, Pages 1509: Photodynamic Therapy Using Talaporfin Sodium for Local Failure after Chemoradiotherapy or Radiotherapy for Esophageal Cancer: A Single Center Experience Journal of Clinical Medicine doi: 10.3390/jcm9051509 Authors: Natsuki Ishida Satoshi Osawa Takahiro Miyazu Masanao Kaneko Satoshi Tamura Shinya Tani Mihoko Yamade Moriya Iwaizumi Yasushi Hamaya Takahisa Furuta Ken Sugimoto A phase II study of second-generation photodynamic therapy...
Sun May 17, 2020 03:00
JCM, Vol. 9, Pages 1510: Imaging Modalities for the Diagnosis of Vascular Graft Infections: A Consensus Paper amongst Different Specialists Journal of Clinical Medicine doi: 10.3390/jcm9051510 Authors: Chiara Lauri Roberto Iezz Michele Rossi Giovanni Tinelli Simona Sica Alberto Signore Alessandro Posa Alessandro Tanzilli Chiara Panzera Maurizio Taurino Paola Anna Erba Yamume Tshomba Vascular graft infection (VGI) is a rare but severe complication of vascular...
Sun May 17, 2020 03:00
JCM, Vol. 9, Pages 1508: Advancing the Science and Management of Renal Cell Carcinoma: Bridging the Divide between Academic and Community Practices Journal of Clinical Medicine doi: 10.3390/jcm9051508 Authors: Nicholas J. Salgia Errol J. Philip Mohammadbagher Ziari Kelly Yap Sumanta Kumar Pal The treatment of metastatic renal cell carcinoma (mRCC) has rapidly evolved; however, the progress made in the field is heavily contingent upon timely and efficient accrual to clinical...
Sun May 17, 2020 03:00
JCM, Vol. 9, Pages 1507: Trauma Can Induce Telangiectases in Hereditary Hemorrhagic Telangiectasia Journal of Clinical Medicine doi: 10.3390/jcm9051507 Authors: Urban Geisthoff Ha-Long Nguyen Rolf Lefering Steffen Maune Kruthika Thangavelu Freya Droege Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease of the fibrovascular tissue resulting in visceral vascular malformations and (muco-) cutaneous telangiectases with recurrent bleedings. The mechanism...
Sun May 17, 2020 03:00
JCM, Vol. 9, Pages 1506: Effects of Steam Sterilization on 3D Printed Biocompatible Resin Materials for Surgical Guides—An Accuracy Assessment Study Journal of Clinical Medicine doi: 10.3390/jcm9051506 Authors: Sharma Cao Msallem Kunz Brantner Honigmann Thieringer Computer-assisted surgery with three-dimensional (3D) printed surgical guides provides more accurate results than free-hand surgery. Steam sterilization could be one of the factors that affect the dimensions...
Sun May 17, 2020 03:00
JCM, Vol. 9, Pages 1505: EPICANCER—Cancer Patients Presenting to the Emergency Departments in France: A Prospective Nationwide Study Journal of Clinical Medicine doi: 10.3390/jcm9051505 Authors: Olivier Peyrony Jean-Paul Fontaine Sébastien Beaune Abdo Khoury Jennifer Truchot Frédéric Balen Rishad Vally Jacques Schmitt Kasarra Ben Hammouda Mélanie Roussel Céline Borzymowski Cécile Vallot Veronique Sanh Elie Azoulay Sylvie Chevret Background: We...
Sun May 17, 2020 03:00
JCM, Vol. 9, Pages 1503: Glaucomatous Maculopathy: Thickness Differences on Inner and Outer Macular Layers between Ocular Hypertension and Early Primary Open-Angle Glaucoma Using 8 × 8 Posterior Pole Algorithm of SD-OCT Journal of Clinical Medicine doi: 10.3390/jcm9051503 Authors: Jose Javier Garcia-Medina Monica del-Rio-Vellosillo Ana Palazon-Cabanes Maria Dolores Pinazo-Duran Vicente Zanon-Moreno Maria Paz Villegas-Perez The purpose of this study was to compare the thickness...
Sat May 16, 2020 03:00
JCM, Vol. 9, Pages 1504: Reproducibility of Ablated Volume Measurement Is Higher with Contrast-Enhanced Ultrasound than with B-Mode Ultrasound after Benign Thyroid Nodule Radiofrequency Ablation—A Preliminary Study Journal of Clinical Medicine doi: 10.3390/jcm9051504 Authors: Simone Schiaffino Francesca Serpi Duccio Rossi Valerio Ferrara Ciriaco Buonomenna Marco Alì Lorenzo Monfardini Luca Maria Sconfienza Giovanni Mauri The reproducibility of contrast-enhanced...
Sat May 16, 2020 03:00
JCM, Vol. 9, Pages 1501: Contemporary Management of Acute Lower Limb Ischemia: Determinants of Treatment Choice Journal of Clinical Medicine doi: 10.3390/jcm9051501 Authors: Lukasiewicz The role of endovascular procedures in the treatment of acute lower limb ischemia (ALI) is expanding. For treatment, the choice between surgical or endovascular is still debated. The aim of this study was to identify factors that determine the selection of treatment. This study included 307 ALI patients...
Sat May 16, 2020 03:00
JCM, Vol. 9, Pages 1502: Different Shades of L1CAM in the Pathophysiology of Cancer Stem Cells Journal of Clinical Medicine doi: 10.3390/jcm9051502 Authors: Giordano Cavallaro L1 cell adhesion molecule (L1CAM) is aberrantly expressed in several tumor types where it is causally linked to malignancy and therapy resistance, acting also as a poor prognosis factor. Accordingly, several approaches have been developed to interfere with L1CAM function or to deliver cytotoxic agents to L1CAM-expressing...
Sat May 16, 2020 03:00
JCM, Vol. 9, Pages 1499: Epigenetic Regulation of Alternative mRNA Splicing in Dilated Cardiomyopathy Journal of Clinical Medicine doi: 10.3390/jcm9051499 Authors: Weng-Tein Gi Jan Haas Farbod Sedaghat-Hamedani Elham Kayvanpour Rewati Tappu David Hermann Lehmann Omid Shirvani Samani Michael Wisdom Andreas Keller Hugo A. Katus Benjamin Meder In recent years, the genetic architecture of dilated cardiomyopathy (DCM) has been more thoroughly elucidated. However,...
Sat May 16, 2020 03:00
JCM, Vol. 9, Pages 1500: Cone Dystrophies: An Optical Coherence Tomography Angiography Study Journal of Clinical Medicine doi: 10.3390/jcm9051500 Authors: Lisa Toto Maurizio Battaglia Parodi Rossella D’Aloisio Stefano Mercuri Alfonso Senatore Luca Di Antonio Guido Di Marzio Marta Di Nicola Rodolfo Mastropasqua Background: This study investigates the relationship between retinal vascularization and macular function in patients with cone dystrophies (CDs)....
Sat May 16, 2020 03:00
JCM, Vol. 9, Pages 1497: Family Caregiver Strain and Challenges When Caring for Orthopedic Patients: A Systematic Review Journal of Clinical Medicine doi: 10.3390/jcm9051497 Authors: Umile Giuseppe Longo Maria Matarese Valeria Arcangeli Viviana Alciati Vincenzo Candela Gabriella Facchinetti Anna Marchetti Maria Grazia De Marinis Vincenzo Denaro Background: Caregivers represent the core of patients’ care in hospital structures, in the process of care...
Sat May 16, 2020 03:00
JCM, Vol. 9, Pages 1498: Initial Steps for the Development of a Phage-Mediated Gene Replacement Therapy Using CRISPR-Cas9 Technology Journal of Clinical Medicine doi: 10.3390/jcm9051498 Authors: Jordi Yang Zhou Keittisak Suwan Amin Hajitou p53 gene (TP53) replacement therapy has shown promising results in cancer gene therapy. However, it has been hampered, mostly because of the gene delivery vector of choice. CRISPR-Cas9 technology (clustered regularly interspaced short palindromic...
Sat May 16, 2020 03:00
JCM, Vol. 9, Pages 1496: Current and Desired Quality of Life in People with Parkinson’s Disease: the Calman Gap Increases with Depression Journal of Clinical Medicine doi: 10.3390/jcm9051496 Authors: Prell Teschner Witte Kunze Hopes and expectations often differ from current experiences. This so-called Calman gap influences quality of life (QoL). We investigated this gap in 77 elderly patients with Parkinson’s disease (PD), 25 patients with epilepsy, and 39 age-matched...
Fri May 15, 2020 03:00
JCM, Vol. 9, Pages 1493: Population-Based Screening or Targeted Screening Based on Initial Clinical Risk Assessment for Atrial Fibrillation: A Report from the Huawei Heart Study Journal of Clinical Medicine doi: 10.3390/jcm9051493 Authors: Yutao Guo Hao Wang Hui Zhang Yundai Chen Gregory Y. H. Lip Background: A general-population approach has been advocated to improve the screening of patients with atrial fibrillation (AF). A more pragmatic alternative may be targeted screening...
Fri May 15, 2020 03:00
JCM, Vol. 9, Pages 1495: Update for Anaesthetists on Clinical Features of COVID-19 Patients and Relevant Management Journal of Clinical Medicine doi: 10.3390/jcm9051495 Authors: Benedikt Preckel Marcus J. Schultz Alexander P. Vlaar Abraham H. Hulst Jeroen Hermanides Menno D. de Jong Wolfgang S. Schlack Markus F. Stevens Robert P. Weenink Markus W. Hollmann When preparing for the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection...
Fri May 15, 2020 03:00
JCM, Vol. 9, Pages 1494: Marine Polyhydroxynaphthoquinone, Echinochrome A: Prevention of Atherosclerotic Inflammation and Probable Molecular Targets Journal of Clinical Medicine doi: 10.3390/jcm9051494 Authors: Artyukov Zelepuga Bogdanovich Lupach Novikov Rutckova Kozlovskaya The effect of low doses of echinochrome A (EchA), a natural polyhydroxy-1,4-naphthoquinone pigment from the sea urchin Scaphechinus mirabilis, has been studied in clinical trials, when it...
Fri May 15, 2020 03:00
JCM, Vol. 9, Pages 1492: Forecasting COVID-19-Associated Hospitalizations under Different Levels of Social Distancing in Lombardy and Emilia-Romagna, Northern Italy: Results from an Extended SEIR Compartmental Model Journal of Clinical Medicine doi: 10.3390/jcm9051492 Authors: Chiara Reno Jacopo Lenzi Antonio Navarra Eleonora Barelli Davide Gori Alessandro Lanza Riccardo Valentini Biao Tang Maria Pia Fantini The outbreak of coronavirus disease 2019 (COVID-19)...
Fri May 15, 2020 03:00
JCM, Vol. 9, Pages 1488: Combined Use of Febuxostat and Colchicine Does Not Increase Acute Hepatotoxicity in Patients with Gout: A Retrospective Study Journal of Clinical Medicine doi: 10.3390/jcm9051488 Authors: Yoon-Jeong Oh Ki Won Moon Colchicine has been effectively used to prevent acute flares in patients with gout, but drug-related adverse events have frequently occurred. We investigated whether colchicine therapy with febuxostat is associated with hepatotoxicity in gout patients....
Fri May 15, 2020 03:00
JCM, Vol. 9, Pages 1491: Use of Saliva for Diagnosis and Monitoring the SARS-CoV-2: A General Perspective Journal of Clinical Medicine doi: 10.3390/jcm9051491 Authors: Ceron Lamy Martinez-Subiela Lopez-Jornet Capela e Silva Eckersall Tvarijonaviciute In this report, updated information and future perspectives about the use of saliva as a sample for laboratory analysis of the Covid-19 are highlighted. Saliva can be used for the direct detection of the SARS-CoV-2...
Fri May 15, 2020 03:00
JCM, Vol. 9, Pages 1490: Interactions between Amyloid-Β Proteins and Human Brain Pericytes: Implications for the Pathobiology of Alzheimer’s Disease Journal of Clinical Medicine doi: 10.3390/jcm9051490 Authors: Donald J. Alcendor Alzheimer’s disease (AD) is a progressive neurodegenerative disease that is the most common cause of dementia, especially among aging populations. Despite advances in AD research, the underlying cause and the discovery of disease-modifying treatments...
Fri May 15, 2020 03:00
JCM, Vol. 9, Pages 1489: Summary-Based Methylome-Wide Association Analyses Suggest Potential Genetically Driven Epigenetic Heterogeneity of Alzheimer’s Disease Journal of Clinical Medicine doi: 10.3390/jcm9051489 Authors: Alireza Nazarian Anatoliy I. Yashin Alexander M. Kulminski Alzheimer’s disease (AD) is a progressive neurodegenerative disorder with no curative treatment available. Exploring the genetic and non-genetic contributors to AD pathogenesis is essential to...
Fri May 15, 2020 03:00
JCM, Vol. 9, Pages 1487: Clinician Assessment Tools for Patients with Diabetic Foot Disease: A Systematic Review Journal of Clinical Medicine doi: 10.3390/jcm9051487 Authors: Raúl Fernández-Torres María Ruiz-Muñoz Alberto J. Pérez-Panero Jerónimo C. García-Romero Manuel Gónzalez-Sánchez The amputation rate in patients with diabetes is 15 to 40 times higher than in patients without diabetes. To avoid major complications, the identification of high-risk in patients with diabetes...
Fri May 15, 2020 03:00
JCM, Vol. 9, Pages 1486: Thoracic Ultrasound for Immediate Exclusion of Pneumothorax after Interventional Bronchoscopy Journal of Clinical Medicine doi: 10.3390/jcm9051486 Authors: Stephan Eisenmann Jane Winantea Rüdiger Karpf-Wissel Faustina Funke Elena Stenzel Christian Taube Kaid Darwiche Background. Pneumothorax is a common side effect in interventional pulmonology. The ideal moment for detection with chest X-ray or ultrasound has not yet been defined. Earlier studies...
Fri May 15, 2020 03:00
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