Navidea Biopharmaceuticals has reclaimed marketing and distribution rights...Read more on AuntMinnieEurope.comRelated Reading: Navidea brings Lymphoseek to Europe Navidea gets $1M for 2 Lymphoseek milestones Navidea's Lymphoseek makes progress in Europe Navidea's PET agent featured at German nuclear medicine congress Navidea reports completion of clinical trial
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The latest coronavirus news updated every day including coronavirus cases, the latest news, features and interviews from New Scientist and essential information about the covid-19 pandemic
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A single-institution study of intraoperative radiation therapy (IORT) using electronic brachytherapy
Abstract Objective Two prospective randomized trials, TARGIT-A and ELIOT, have shown intraoperative radiation (IORT) to be safe and well-tolerated in low-risk patients. Electronic IORT with the Xoft Axxent system has few long-term reported results. Materials/methods A total of 100 patients (101 tumors) were treated with partial mastectomy and intraoperative...
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Publication date: April–June 2020Source: Revista de Logopedia, Foniatría y Audiología, Volume 40, Issue 2Author(s): Anabel González Cano, Rosa Belén Santiago Pardo
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Publication date: April–June 2020Source: Revista de Logopedia, Foniatría y Audiología, Volume 40, Issue 2Author(s): Luisa Muñoz García, Francisco Carrero Barril
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Publication date: April–June 2020Source: Revista de Logopedia, Foniatría y Audiología, Volume 40, Issue 2Author(s): Cristina Lana Pérez, Fernando López Álvarez, Paloma Sirgo Rodríguez
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Publication date: April–June 2020Source: Revista de Logopedia, Foniatría y Audiología, Volume 40, Issue 2Author(s): Marta Suárez Suárez, María Verónica Martínez López
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Publication date: April–June 2020Source: Revista de Logopedia, Foniatría y Audiología, Volume 40, Issue 2Author(s): Natalia Pérez Niculcar, César Antonio Álvarez Marcos, Liliana Santamarina Rabanal
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Publication date: April–June 2020Source: Revista de Logopedia, Foniatría y Audiología, Volume 40, Issue 2Author(s): Ana Cristina Martín Crespo, Luis Andrés Castejón Fernández
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Publication date: April–June 2020Source: Revista de Logopedia, Foniatría y Audiología, Volume 40, Issue 2Author(s): Myrian García González, Sandra Espino Datsira, Diana Grandi de Trepat
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Publication date: April–June 2020Source: Revista de Logopedia, Foniatría y Audiología, Volume 40, Issue 2Author(s): Adelina Palma, Ana Lou Moreno
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Publication date: April–June 2020Source: Revista de Logopedia, Foniatría y Audiología, Volume 40, Issue 2Author(s): Eric Bermúdez Cervantes, David García Quintana
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Publication date: April–June 2020Source: Revista de Logopedia, Foniatría y Audiología, Volume 40, Issue 2Author(s): Fernando Cuetos
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Publication date: April–June 2020Source: Revista de Logopedia, Foniatría y Audiología, Volume 40, Issue 2Author(s): Irma Pujol Maculet, David García Quintana
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Publication date: April–June 2020Source: Revista de Logopedia, Foniatría y Audiología, Volume 40, Issue 2Author(s): Paula Resina Curado, Naymé Salas
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Publication date: April–June 2020Source: Revista de Logopedia, Foniatría y Audiología, Volume 40, Issue 2Author(s): Alba López Sánchez, Natalia Jimeno Bulnes
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Abstract Purpose To examine associations of KRAS mutation with tumor deposit status and overall survival in colorectal cancer (CRC) patients. Methods This retrospective cohort study included patients with incidental CRC diagnosed during 2010–2014 and recorded statuses of KRAS and tumor deposit in the National Cancer Database of the USA. Multivariable logistic...
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Abstract Purpose Kidney cancer survivors spend large quantities of time sedentary and little time physically active, which negatively impacts quality of life (QoL). This study examined (1) the association of reallocating sedentary time to sleep, light physical activity (PA), or moderate-to-vigorous PA (MVPA) on QoL in kidney cancer survivors and (2) the threshold at which results are clinically meaningful. ...
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Abstract Congruent, low-friction relative movement between the articulating elements of a synovial joint is an essential pre-requisite for sustained, efficient, function. Where disorders of joint formation or maintenance exist, mechanical overloading and osteoarthritis (OA) follow. The heritable component of OA accounts for ~ 50% of susceptible risk. Although almost 100 genetic risk loci for OA have now been identified, and the epidemiological relationship between joint development,...
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Objective. To identify susceptibility modules and genes for cardiovascular disease in diabetic patients using weighted gene coexpression network analysis (WGCNA). Methods. The raw data of GSE13760 were downloaded from the Gene Expression Omnibus (GEO) website. Genes with a false discovery and a log2 fold were included in the analysis. WGCNA was used to build a gene coexpression network, screen important modules, and filter the hub genes. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes...
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In order to explore the transverse bending responses of carbon fiber-reinforced polymer (CFRP) square tubes filled with aluminum foam, the three-point bending tests were carried out on an INSTRON machine, the full-field deformation measurement was performed using a 3D-DIC test system, the numerical model was established by ABAQUS/Explicit, and the bending stiffness was calculated by the improved analytical model based on shear-deformable beam theory. The discrepancies of experimental data, numerical...
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This study identified 57 basic leucine zipper (bZIP) genes from the pineapple genome, and the analysis of these bZIP genes was focused on the evolution and divergence after multiple duplication events in relation to the pineapple genome fusion. According to bioinformatics analysis of a phylogenetic tree, the bZIP gene family was divided into 11 subgroups in pineapple, Arabidopsis, and rice; gene structure and conserved motif analyses showed that bZIP genes within the same subgroup shared similar...
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This paper considers the pricing of the CatEPut option (catastrophe equity put option) in a mixed fractional model in which the stock price is governed by a mixed fractional Brownian motion (mfBM model), which manifests long-range correlation and fluctuations from the financial market. Using the conditional expectation and the change of measure technique, we obtain an analytical pricing formula for the CatEPut option when the short interest rate is a deterministic and time-dependent function. Furthermore,...
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In this paper, we study the quasilinear Schrödinger equation involving concave and convex nonlinearities. When the pair of parameters belongs to a certain subset of , we establish the existence of a nontrivial mountain pass-type solution and infinitely many negative energy solutions by using some new techniques and dual fountain theorem. Recent results from the literature are improved and extended.
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Brucellosis is a zoonotic infection caused by Gram-negative bacteria of genus Brucella. The disease is of public health, veterinary, and economic significance in most of the developed and developing countries. Direct contact between susceptible and infective animals or their contaminated products are the two major routes of the disease transmission. In this paper, we investigate the impacts of controls of livestock vaccination, gradual culling through slaughter of seropositive cattle and small ruminants,...
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Purpose. Difficulties with sensory processing are known to have negative effects on individuals’ attachment styles and the interpersonal domain. We investigated the relationships among sensory processing styles, attachment styles, and interpersonal problems to better understand the role of attachment styles on the relationship between sensory processing styles and interpersonal problems. Participants. One-hundred and eighty-four university students (aged 18-28 years) completed a set of self-reported...
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The chemotherapeutic and immunosuppressive agent cyclophosphamide has previously been shown to induce complications within the setting of bone marrow transplantation. More recently, cardiotoxicity has been shown to be a dose-limiting factor during cyclophosphamide therapy, and cardiooncology is getting wider attention. Though mechanism of cyclophosphamide-induced cardiotoxicity is not completely understood, it is thought to encompass oxidative and nitrative stress. As such, this review focuses on...
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With the rise of big data in cloud computing, many optimization problems have gradually developed into high-dimensional large-scale optimization problems. In order to address the problem of dimensionality in optimization for genetic algorithms, an adaptive dimensionality reduction genetic optimization algorithm (ADRGA) is proposed. An adaptive vector angle factor is introduced in the algorithm. When the angle of an individual’s adjacent dimension is less than the angle factor, the value of the smaller...
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Background. The data on clinical practice patterns in the evaluation and management of Graves’ disease (GD) are limited in Asia. The aims of this survey were to report the current practices in the management of GD in Thailand and to examine any international differences in the management of GD. Methods. Members of the Endocrine Society of Thailand who were board certified in endocrinology (N = 392) were invited to participate in an electronic survey on the management of GD using the same index case...
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The study examined kinematic parameters and their inter- and intrasubject variability in the topspin forehand of seven top-level table tennis players. A wireless inertial measurement unit (IMU) system measured the movement of the playing hand to analyze the Ready position, Backswing, and Forward events, and a racket-mounted piezoelectric sensor captured the racket-ball Contact. In a four-phase cycle (Backswing, Hitting, Followthrough, and Back to Ready position), body sensors recorded the cycle and...
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Background. Helicobacter pylori (H. pylori) is a common and universally distributed bacterial infection. However, in children, active gastritis and ulcer are rarely seen. Objectives. The aims of this study were to establish the prevalence of H. pylori infection and to compare the clinical, endoscopic, and histopathological findings between infected and noninfected pediatric patients at Makassed General Hospital. Methods. Patients aged between 1 month and 17 years who underwent upper gastrointestinal...
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With the rapid development of quantum computing and quantum information technology, the universal quantum computer will emerge in the near decades with a very high probability and it could break most of the current public key cryptosystems totally. Due to the ability of withstanding the universal quantum computer’s attack, the lattice-based cryptosystems have received lots of attention from both industry and academia. In this paper, we propose an identity-based blind signature scheme using lattice....
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To solve the problems of high complexity and low accuracy in Volterra time-domain kernel calculation of a nonlinear system, this paper proposes an intelligent calculation method of Volterra time-domain kernel by time-delay artificial neural networks (TDANNs) and also designs a root mean square error (RMSE) index to choose the neuron number of the network input layer. Firstly, a three-layer TDANN is designed according to the characteristics of the Volterra model. Secondly, the relationship between...
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Geometric nonlinearity (GN) and initial internal forces (IIFs) are the basic characteristics of cable-stayed bridges, but now there is no effective method for analyzing the effect of them on bridge-track interaction of continuous welded rail (CWR) on cable-stayed bridge. A method for reconstructing the displacement-force curve of ballast longitudinal resistance was put forward according to the deformation of cable-stayed bridges under the completed bridge state. A feasibility study on the method...
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We study the local and global bifurcation of nonnegative nonconstant solutions of a discrete general Brusselator model. We generalize the linear in the standard Brusselator model to the nonlinear . Assume that is a strictly increasing function, and . Taking as the bifurcation parameter, we obtain that the solution set of the problem constitutes a constant solution curve and a nonconstant solution curve in a small neighborhood of the bifurcation point . Moreover, via the Rabinowitz bifurcation...
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Introduction. Alzheimer’s disease (AD), the most common neurodegenerative disorder, is characterized by the accumulation of amyloid-β (Aβ) peptide and hyperphosphorylated tau protein. Accumulating evidence has revealed that the slow progressive deterioration of AD is associated with oxidative stress and chronic inflammation in the brain. Nuclear factor erythroid 2- (NF-E2-) related factor 2 (Nrf2), which acts through the Nrf2/ARE pathway, is a key regulator of the antioxidant and anti-inflammatory...
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This study is aimed at providing a numerical derivation of the shell knockdown factors of isogrid-stiffened cylinders under axial compressive loads. The present work uses two different analysis models such as the detailed model with modeling of numerous stiffeners and the equivalent model without modeling of stiffeners for isogrid-stiffened cylinders. The single perturbation load approach is used to represent the geometrically initial imperfection of the cylinder. Postbuckling analyses using the...
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This paper is focused on a kind of distributed optimal control design for a class of switched nonlinear systems with the state time delay which have a prescribed switching sequence. Firstly, we design a bounded controller to make the system stable for each mode of the nominal system. Then, a distributed optimal controller which can satisfy input constraint is designed based on the bounded stabilization controller. A sufficient condition to guarantee ultimate boundedness of the system is given based...
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