Pathogens, Vol. 9, Pages 340: Pathogenomics and Management of Fusarium Diseases in Plants Pathogens doi: 10.3390/pathogens9050340 Authors: Rampersad There is an urgency to supplant the heavy reliance on chemical control of Fusarium diseases in different economically important, staple food crops due to development of resistance in the pathogen population, the high cost of production to the risk-averse grower, and the concomitant environmental impacts. Pathogenomics has enabled (i) the...
Fri May 01, 2020 03:00
Pathogens, Vol. 9, Pages 341: Detection of Porcine Circovirus 3 in Wildlife Species in Spain Pathogens doi: 10.3390/pathogens9050341 Authors: Ewelina Czyżewska-Dors José I. Núñez Viviane Saporiti Eva Huerta Carme Riutord Oscar Cabezón Joaquim Segalés Marina Sibila Porcine circovirus 3 (PCV-3) is the third member of the family Circoviridae, genus Circovirus, able to infect swine. A high prevalence of viral DNA has been recorded in wild boars. Recently, PCV-3 DNA was...
Fri May 01, 2020 03:00
Pathogens, Vol. 9, Pages 339: Tripartite Interactions among Ixodiphagus hookeri, Ixodes ricinus and Deer: Differential Interference with Transmission Cycles of Tick-Borne Pathogens Pathogens doi: 10.3390/pathogens9050339 Authors: Aleksandra I. Krawczyk Julian W. Bakker Constantianus J. M. Koenraadt Manoj Fonville Katsuhisa Takumi Hein Sprong Samiye Demir For the development of sustainable control of tick-borne diseases, insight is needed in biological factors that affect...
Thu Apr 30, 2020 03:00
Pathogens, Vol. 9, Pages 338: Vaccine-Mediated Mechanisms Controlling Francisella tularensis SCHU S4 Growth in a Rat Co-Culture System Pathogens doi: 10.3390/pathogens9050338 Authors: Helena Lindgren Kjell Eneslätt Igor Golovliov Carl Gelhaus Patrik Rydén Terry Wu Anders Sjöstedt Francisella tularensis causes the severe disease tularemia. In the present study, the aim was to identify correlates of protection in the rat co-culture model by investigating the immune responses...
Thu Apr 30, 2020 03:00
Pathogens, Vol. 9, Pages 337: Focus of Ongoing Onchocerciasis Transmission Close to Bangui, Central African Republic Pathogens doi: 10.3390/pathogens9050337 Authors: Smet Metanmo Mbelesso Kemata Fodjo Boumédiène Ekwoge Yangatimbi Ajzenberg Badibanga Preux Colebunders Recently, there were anecdotal reports of a high number of persons with epilepsy, including children with nodding seizures in the Landja Mboko area located about 9 km from the...
Thu Apr 30, 2020 03:00
Pathogens, Vol. 9, Pages 336: Epidemiologic Survey on Toxoplasma gondii and Trichinella pseudospiralis Infection in Corvids from Central Italy Pathogens doi: 10.3390/pathogens9050336 Authors: Francesca Mancianti Giuliana Terracciano Camilla Sorichetti Giuseppe Vecchio Daniele Scarselli Stefania Perrucci Free-ranging corvids—678 magpies (Pica pica) and 120 hooded crows (Corvus cornix) from nine protected areas of the Pisa province (central Italy)—were...
Thu Apr 30, 2020 03:00
Pathogens, Vol. 9, Pages 334: Genetic Diversity and Sequence Polymorphism of Two Genes Encoding Theileria parva Antigens Recognized by CD8+ T Cells among Vaccinated and Unvaccinated Cattle in Malawi Pathogens doi: 10.3390/pathogens9050334 Authors: Chatanga Hayashida Muleya Kusakisako Moustafa Salim Katakura Sugimoto Nonaka Nakao East Coast fever (ECF) is an acute fatal tick-borne disease of cattle caused by Theileria parva. It causes major losses...
Thu Apr 30, 2020 03:00
Pathogens, Vol. 9, Pages 335: Genotyping, Assessment of Virulence and Antibacterial Resistance of the Rostov Strain of Mycobacterium tuberculosis Attributed to the Central Asia Outbreak Clade Pathogens doi: 10.3390/pathogens9050335 Authors: Mikhail V. Fursov Egor A. Shitikov Julia A. Bespyatykh Alexander G. Bogun Angelina A. Kislichkina Tatiana I. Kombarova Tatiana I. Rudnitskaya Natalia S. Grishenko Elena A. Ganina Lubov V. Domotenko Nadezhda K. Fursova Vasiliy...
Thu Apr 30, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 87: Vasorelaxant Effects Induced by Red Wine and Pomace Extracts of Magliocco Dolce cv. Pharmaceuticals doi: 10.3390/ph13050087 Authors: Gabriele Carullo Amer Ahmed Fabio Fusi Fabio Sciubba Maria Enrica Di Cocco Donatella Restuccia Umile Gianfranco Spizzirri Simona Saponara Francesca Aiello Several epidemiological studies demonstrate that moderate (red) wine consumption may afford protection against cardiovascular diseases. Protection...
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Pharmaceuticals, Vol. 13, Pages 86: Crosslinked Fibroin Nanoparticles: Investigations on Biostability, Cytotoxicity, and Cellular Internalization Pharmaceuticals doi: 10.3390/ph13050086 Authors: Duy Toan Pham Nuttawut Saelim Raphaël Cornu Arnaud Béduneau Waree Tiyaboonchai Recently, crosslinked fibroin nanoparticles (FNP) using the crosslinker 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) or the polymer poly(ethylenimine) (PEI) have been developed and...
Thu Apr 30, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 85: The Impact of Iron Supplementation for Treating Anemia in Patients with Chronic Kidney Disease: Results from Pairwise and Network Meta-Analyses of Randomized Controlled Trials Pharmaceuticals doi: 10.3390/ph13050085 Authors: Marcel Adler Francisco Herrera-Gómez Débora Martín-García Marie Gavid F. Javier Álvarez Carlos Ochoa-Sangrador After relative erythropoietin deficiency, iron deficiency is the second most important contributing factor...
Thu Apr 30, 2020 03:00
Pharmaceutics, Vol. 12, Pages 421: Encapsulating TGF-β1 Inhibitory Peptides P17 and P144 as a Promising Strategy to Facilitate Their Dissolution and to Improve Their Functionalization Pharmaceutics doi: 10.3390/pharmaceutics12050421 Authors: Hanafy Fabregat Leporatti Kemary : Transforming growth factor-beta (TGFβ1) is considered as a master regulator for many intracellular signaling pathways, including proliferation, differentiation and death, both in health and...
Sat May 02, 2020 03:00
Pharmaceutics, Vol. 12, Pages 420: Biphasic Dissolution as an Exploratory Method During Early Drug Product Development Pharmaceutics doi: 10.3390/pharmaceutics12050420 Authors: Silva Al-Gousous Davies Chacra Webster Lipka Amidon Löbenberg Dissolution testing is a major tool used to assess a drug product’s performance and as a quality control test for solid oral dosage forms. However, compendial equipment and methods may lack discriminatory power...
Sat May 02, 2020 03:00
Pharmaceutics, Vol. 12, Pages 419: Characterization of Phenolic Acid Antimicrobial and Antioxidant Structure–Property Relationships Pharmaceutics doi: 10.3390/pharmaceutics12050419 Authors: Liu Du Beaman Monroe Keywords: phenolic acids; antimicrobial; antioxidant
Sat May 02, 2020 03:00
Pharmaceutics, Vol. 12, Pages 418: Nanoparticles to Improve the Efficacy of Vaccines Pharmaceutics doi: 10.3390/pharmaceutics12050418 Authors: Yun Cho This editorial aims to summarize the nine scientific papers that contributed to the Special Issue entitled ‘Nanoparticles to Improve the Efficacy of Vaccines’.
Sat May 02, 2020 03:00
Pharmaceutics, Vol. 12, Pages 417: Interpretation of Drug Interaction Using Systemic and Local Tissue Exposure Changes Pharmaceutics doi: 10.3390/pharmaceutics12050417 Authors: Choi Systemic exposure of a drug is generally associated with its pharmacodynamic (PD) effect (e.g., efficacy and toxicity). In this regard, the change in area under the plasma concentration-time curve (AUC) of a drug, representing its systemic exposure, has been mainly considered in evaluation of drug-drug interactions...
Sat May 02, 2020 03:00
Pharmaceutics, Vol. 12, Pages 416: Glyceraldehyde-3-phosphate Dehydrogenase is a Multifaceted Therapeutic Target Pharmaceutics doi: 10.3390/pharmaceutics12050416 Authors: Vladimir F. Lazarev Irina V. Guzhova Boris A. Margulis Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a glycolytic enzyme whose role in cell metabolism and homeostasis is well defined, while its function in pathologic processes needs further elucidation. Depending on the cell context, GAPDH may bind a number...
Sat May 02, 2020 03:00
Pharmaceutics, Vol. 12, Pages 415: Periodic DFT Calculations—Review of Applications in the Pharmaceutical Sciences Pharmaceutics doi: 10.3390/pharmaceutics12050415 Authors: Mazurek Szeleszczuk Pisklak In the introduction to this review the complex chemistry of solid-state pharmaceutical compounds is summarized. It is also explained why the density functional theory (DFT) periodic calculations became recently so popular in studying the solid APIs (active pharmaceutical ingredients)....
Fri May 01, 2020 03:00
Pharmaceutics, Vol. 12, Pages 412: Pharmaceutical Particulates and Membranes for the Delivery of Drugs and Bioactive Molecules Pharmaceutics doi: 10.3390/pharmaceutics12050412 Authors: Diganta B. Das Mostafa Mabrouk Hanan H. Beherei G. Arthanareeswaran The delivery of drugs and bioactive molecules using pharmaceutical particulates and membranes are of great significance for various applications such as the treatment of secondary infections, cancer treatment, skin regeneration,...
Fri May 01, 2020 03:00
Pharmaceutics, Vol. 12, Pages 414: Pyrrolylquinoxaline-2-One Derivative as a Potent Therapeutic Factor for Brain Trauma Rehabilitation Pharmaceutics doi: 10.3390/pharmaceutics12050414 Authors: Dutysheva Mikeladze Trestsova Aksenov Utepova Mikhaylova Suezov Charushin Chupakhin Guzhova Margulis Lazarev Traumatic brain injury (TBI) often causes massive brain cell death accompanied by the accumulation of toxic factors in interstitial and cerebrospinal...
Thu Apr 30, 2020 03:00
Pharmaceutics, Vol. 12, Pages 413: Automated Real-Time Tumor Pharmacokinetic Profiling in 3D Models: A Novel Approach for Personalized Medicine Pharmaceutics doi: 10.3390/pharmaceutics12050413 Authors: Jan F. Joseph Leonie Gronbach Jill García-Miller Leticia M. Cruz Bernhard Wuest Ulrich Keilholz Christian Zoschke Maria K. Parr Cancer treatment often lacks individual dose adaptation, contributing to insufficient efficacy and severe side effects. Thus, personalized...
Thu Apr 30, 2020 03:00
Pharmaceutics, Vol. 12, Pages 411: Automated Large-Scale Production of Paclitaxel Loaded Mesenchymal Stromal Cells for Cell Therapy Applications Pharmaceutics doi: 10.3390/pharmaceutics12050411 Authors: Daniela Lisini Sara Nava Simona Frigerio Simona Pogliani Guido Maronati Angela Marcianti Valentina Coccè Gianpietro Bondiolotti Loredana Cavicchini Francesca Paino Francesco Petrella Giulio Alessandri Eugenio A. Parati Augusto Pessina Mesenchymal...
Thu Apr 30, 2020 03:00
Pharmacy, Vol. 8, Pages 77: “The Difference between Plan b and ella®? They’re Basically the Same Thing”: Results from a Mystery Client Study Pharmacy doi: 10.3390/pharmacy8020077 Authors: Guneet Kaur Tiana Fontanilla Holly Bullock Mary Tschann Pharmacy staff can serve an important role educating patients about emergency contraceptive pills (ECP), particularly ulipristal acetate (UPA), which requires a prescription. We conducted a secondary analysis of a previously completed...
Fri May 01, 2020 03:00
Pharmacy, Vol. 8, Pages 76: Exploring the Availability of Emergency Contraception in New Brunswick Pharmacies: A Mystery-Client Telephone Study Pharmacy doi: 10.3390/pharmacy8020076 Authors: Madison Borsella Angel M. Foster Although levonorgestrel-only emergency contraceptive pills (LNg-ECPs) have been available over the counter in Canada for more than a decade, barriers to access persist. We aimed to obtain information about the availability and cost of LNg-ECPs in New Brunswick....
Thu Apr 30, 2020 03:00
Plants, Vol. 9, Pages 584: Why Seed Physiology Is Important for Genebanking Plants doi: 10.3390/plants9050584 Authors: Whitehouse Hay Lusty Genebank management is a field in its own right; it is multifaceted, requiring a diverse set of skills and knowledge. Seed physiology is one area that is critical to the successful operation of seed genebanks, requiring understanding of seed quality during development and maturation, seed dormancy and germination, and seed longevity in storage...
Sat May 02, 2020 03:00
Plants, Vol. 9, Pages 585: Genome-Wide Association Analysis Identifies Candidate Genes Regulating Seed Number Per Silique in Arabidopsis thaliana Plants doi: 10.3390/plants9050585 Authors: Jiang Hong Jiang Yu Zhang Shi Lin Seed weight and number ultimately determine seed yield. Arabidopsis seed number comprised of silique number and seed number per silique (SNS). Comparing seed development and weight, determinants of seed number remain largely uncharacterized....
Sat May 02, 2020 03:00
Plants, Vol. 9, Pages 581: Does Storage under Gene Bank Conditions Affect Seed Germination and Seedling Growth? The Case of Senecio morisii (Asteraceae), a Vascular Plant Exclusive to Sardinian Water Meadows Plants doi: 10.3390/plants9050581 Authors: Alba Cuena-Lombraña Martina Sanna Marco Porceddu Gianluigi Bacchetta Understanding seed viability under long-term storage conditions provides basic and useful information to investigate the effectiveness of seed banking. Besides...
Sat May 02, 2020 03:00
Plants, Vol. 9, Pages 583: Response to Anthracnose in a Tarwi (Lupinus mutabilis) Collection Is Influenced by Anthocyanin Pigmentation Plants doi: 10.3390/plants9050583 Authors: Guilengue Neves-Martins Talhinhas Anthracnose, caused by Colletotrichum lupini, is a major limiting factor for lupin production. Tarwi or Andean Lupin (Lupinus mutabilis) is generally regarded as susceptible to anthracnose, but the high protein and oil content of its seeds raise interest in promoting...
Sat May 02, 2020 03:00
Plants, Vol. 9, Pages 582: Ethylene is Involved in Symptom Development and Ribosomal Stress of Tomato Plants upon Citrus Exocortis Viroid Infection Plants doi: 10.3390/plants9050582 Authors: Prol López-Gresa Rodrigo Bellés Lisón Citrus exocortis viroid (CEVd) is known to cause different symptoms in citrus trees, and its mechanism of infection has been studied in tomato as an experimental host, producing ribosomal stress on these plants. Some of the symptoms caused by...
Sat May 02, 2020 03:00
Plants, Vol. 9, Pages 580: Phytoremediation Potential of Crop Plants in Countering Nickel Contamination in Carbonation Lime Coming from the Sugar Industry Plants doi: 10.3390/plants9050580 Authors: Arianna De Bernardi Cristiano Casucci Daniela Businelli Roberto D’Amato Gian Maria Beone Maria Chiara Fontanella Costantino Vischetti The phytoremediation potential of four crop species cultivated on carbonation lime coming from the sugar industry with water-soluble nickel...
Sat May 02, 2020 03:00
Plants, Vol. 9, Pages 579: Seed Germination after 30 Years Storage in Permafrost Plants doi: 10.3390/plants9050579 Authors: Solberg Brodal Bothmer Meen Yndgaard Andreasen Asdal More than 30 years ago, the Nordic Gene Bank established a long-term experiment on seeds stored under permafrost conditions in an abandoned mine corridor in Svalbard, as a tool to monitor storage life under these conditions. The study included seeds from 16 Nordic agricultural and horticultural...
Sat May 02, 2020 03:00
Plants, Vol. 9, Pages 576: Arabidopsis in the Wild—The Effect of Seasons on Seed Performance Plants doi: 10.3390/plants9050576 Authors: Deborah de Souza Vidigal Hanzi He Henk W. M. Hilhorst Leo A. J. Willems Leónie Bentsink Climate changes play a central role in the adaptive life histories of organisms all over the world. In higher plants, these changes may impact seed performance, both during seed development and after dispersal. To examine the plasticity of seed performance...
Fri May 01, 2020 03:00
Plants, Vol. 9, Pages 578: Barattiere: An Italian Local Variety of Cucumis melo L. with Quality Traits between Melon and Cucumber Plants doi: 10.3390/plants9050578 Authors: Massimiliano Renna Massimiliano D’Imperio Maria Gonnella Angelo Parente Pietro Santamaria Francesco Serio Barattiere, belonging to the Cucumis melo L. species, is a local variety of Puglia (Southern Italy), which is consumed as a vegetable at the immature stage, like cucumber. In this study, three Barattiere...
Fri May 01, 2020 03:00
Plants, Vol. 9, Pages 577: Cloning and Expression of a Perilla frutescens Cytochrome P450 Enzyme Catalyzing the Hydroxylation of Phenylpropenes Plants doi: 10.3390/plants9050577 Authors: Mariko Baba Ken-ichi Yamada Michiho Ito Phenylpropanoid volatile components in plants are useful and valuable not only as flavorings, but also as medicines and food supplements. The pharmacological actions and toxicities of these compounds have been well studied but their synthetic pathways are...
Fri May 01, 2020 03:00
Plants, Vol. 9, Pages 575: Optimizing N Fertilization to Improve Yield, Technological and Nutritional Quality of Tomato Grown in High Fertility Soil Conditions Plants doi: 10.3390/plants9050575 Authors: Ronga Pentangelo Parisi Processing tomato is the second most important worldwide cash crop, generally produced in high-input systems. However, fruit yield and quality are affected by agronomic management, particularly nitrogen (N) fertilization, whose application to indeterminate...
Fri May 01, 2020 03:00
Plants, Vol. 9, Pages 574: The Role of Mechanoperception in Plant Cell Wall Integrity Maintenance Plants doi: 10.3390/plants9050574 Authors: Laura Bacete Thorsten Hamann The plant cell walls surrounding all plant cells are highly dynamic structures, which change their composition and organization in response to chemical and physical stimuli originating both in the environment and in plants themselves. They are intricately involved in all interactions between plants and their environment...
Fri May 01, 2020 03:00
Plants, Vol. 9, Pages 573: The Consequences of a Disruption in Cyto-Nuclear Coadaptation on the Molecular Response to a Nitrate Starvation in Arabidopsis Plants doi: 10.3390/plants9050573 Authors: Chardon Cueff Delannoy Aubé Lornac Bedu Gilard Pateyron Rogniaux Gargaros Mireau Rajjou Martin-Magniette Budar Mitochondria and chloroplasts are important actors in the plant nutritional efficiency. So, it could be expected that a disruption...
Fri May 01, 2020 03:00
Plants, Vol. 9, Pages 572: Morphological Responses and Gene Expression of Grain Amaranth (Amaranthus spp.) Growing under Cd Plants doi: 10.3390/plants9050572 Authors: Lancíková Tomka Žiarovská Gažo Hricová Phytoremediation efficiency depends on the ability of plants to accumulate, translocate and resist high levels of metals without symptoms of toxicity. This study was conducted to evaluate the potential of grain amaranth for remediation of soils contaminated with Cd....
Thu Apr 30, 2020 03:00
Publications, Vol. 8, Pages 25: The Fast and the FRDR Publications doi: 10.3390/publications8020025 Authors: Turp Wilson Pascoe Garnett The Federated Research Data Repository (FRDR), developed through a partnership between the Canadian Association of Research Libraries’ Portage initiative and the Compute Canada Federation, improves research data discovery in Canada by providing a single search portal for research data stored across Canadian governmental, institutional,...
Sat May 02, 2020 03:00
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