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Τρίτη 18 Αυγούστου 2020

 

Pediatric sarcomas display a variable EpCAM expression in a histology-dependent manner.
Pediatric sarcomas display a variable EpCAM expression in a histology-dependent manner. Transl Oncol. 2020 Aug 14;13(11):100846 Authors: Tombolan L, Rossi E, Zin A, Santoro L, Bonvini P, Zamarchi R, Bisogno G Abstract EpCAM is a transmembrane glycoprotein typically overexpressed in cancer of epithelial origin and mainly involved in the epithelial-to-mesenchymal transition (EMT) of tumor cells that spread and disseminate. Strategies for the...
Rare Cancers
Tue Aug 18, 2020 13:16
Colorectal Adenocarcinomas Harboring ALK Fusion Genes: A Clinicopathologic and Molecular Genetic Study of 12 Cases and Review of the Literature.
Colorectal Adenocarcinomas Harboring ALK Fusion Genes: A Clinicopathologic and Molecular Genetic Study of 12 Cases and Review of the Literature. Am J Surg Pathol. 2020 Sep;44(9):1224-1234 Authors: Lasota J, Chłopek M, Wasąg B, Kowalik A, Christiansen J, Lamoureux J, Kuźniacka A, Felisiak-Gołąbek A, Liu Y, Reyes TAR, Saha R, Agaimy A, Behenska K, Biernat W, Cattaneo L, Centonze G, Daum O, Daumova M, Domagała P, Dziuba I, Geppert CE, Góźdź S, Nasierowska-Guttmejer...
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Tue Aug 18, 2020 13:16
Yttrium-90 radioembolization as a possible new treatment for brain cancer: proof of concept and safety analysis in a canine model.
Related Articles Yttrium-90 radioembolization as a possible new treatment for brain cancer: proof of concept and safety analysis in a canine model. EJNMMI Res. 2020 Aug 17;10(1):96 Authors: Pasciak AS, Manupipatpong S, Hui FK, Gainsburg L, Krimins R, Zink MC, Brayton CF, Morris M, Sage J, Donahue DR, Dreher MR, Kraitchman DL, Weiss CR Abstract PURPOSE: To evaluate the safety, feasibility, and preliminary efficacy of yttrium-90 (90Y) radioembolization...
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Tue Aug 18, 2020 15:09
Colonic clear cell adenocarcinoma with enteroblastic differentiation.
Related Articles Colonic clear cell adenocarcinoma with enteroblastic differentiation. Clin J Gastroenterol. 2020 Aug 17;: Authors: Shiratori Y, Suzuki K, Ikeya T Abstract Adenocarcinoma with enteroblastic differentiation (ACED) has high malignant potential. It is known as clear-cell adenocarcinoma, which is a special type of adenocarcinomas characterized by primitive intestine-like structures. Although ACED is often encountered in the stomach,...
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Tue Aug 18, 2020 15:09
Menetrier disease and Cytomegalovirus infection in paediatric age: report of three cases and a review of the literature.
Related Articles Menetrier disease and Cytomegalovirus infection in paediatric age: report of three cases and a review of the literature. Eur J Pediatr. 2020 Aug 15;: Authors: Barbati F, Marrani E, Indolfi G, Lionetti P, Trapani S Abstract Paediatric Menetrier disease (PMD) is a protein-losing gastropathy, presenting with generalized oedema and abdominal symptoms. PMD commonly has an acute course and may be associated with Cytomegalovirus (CMV)...
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Tue Aug 18, 2020 15:09
Synchronous Primary Endometrial and Ovarian Cancers: Trends and Outcomes of the Rare Disease at a South Asian Tertiary Care Cancer Center.
Related Articles Synchronous Primary Endometrial and Ovarian Cancers: Trends and Outcomes of the Rare Disease at a South Asian Tertiary Care Cancer Center. Cureus. 2020 Jul 13;12(7):e9163 Authors: Khalid N, Ullah F, Zafar H, Anwer AW, Abbas T, Shakeel O, Faisal M, Sadaf T, Syed AA Abstract Background and objective The incidence of synchronous primary endometrial and ovarian cancer is uncommon and poses a diagnostic challenge to the treating...
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Tue Aug 18, 2020 15:09
Prognostic Significance of Rab27A and Rab27B Expression in Esophageal Squamous Cell Cancer.
Related Articles Prognostic Significance of Rab27A and Rab27B Expression in Esophageal Squamous Cell Cancer. Cancer Manag Res. 2020;12:6353-6361 Authors: Yu F, Wu W, Liang M, Huang Y, Chen C Abstract Purpose: Rab27A and Rab27B, members of the Rab family of small GTPases, have aberrant expression and exert different roles in various cancers. However, their expression and potential prognostic values in esophageal squamous cell cancer (ESCC) still...
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Tue Aug 18, 2020 15:09
Chromosomal microarray analysis of benign mesenchymal tumors with RB1 deletion.
Related Articles Chromosomal microarray analysis of benign mesenchymal tumors with RB1 deletion. Hum Pathol. 2020 Jul 22;: Authors: Dusenbery AC, Davick JJ, LeGallo RD, Williams ES Abstract Spindle cell lipomas/pleomorphic lipomas, mammary-type myofibroblastomas, and cellular angiofibromas are benign mesenchymal tumors that demonstrate histologically overlapping features but with varying anatomic locations and an uncertain etiologic relationship....
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Tue Aug 18, 2020 15:09
Four Cases of the Melanotic Variant of Malignant Nerve Sheath Tumour: a Rare, Aggressive Neoplasm in Young Dogs with a Predilection for the Spinal Cord.
Related Articles Four Cases of the Melanotic Variant of Malignant Nerve Sheath Tumour: a Rare, Aggressive Neoplasm in Young Dogs with a Predilection for the Spinal Cord. J Comp Pathol. 2020 Jul;178:1-8 Authors: Warren AL, Miller AD, de Lahunta A, Kortz G, Summers BA Abstract Four cases of a rare melanotic variant of malignant nerve sheath tumour (MNST) in dogs are described. All four cases presented with neurological clinical signs due to multicentric,...
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Tue Aug 18, 2020 15:09
Outcomes with anti-EGFR monoclonal antibodies in metastatic and recurrent anal squamous cell carcinoma.
Related Articles Outcomes with anti-EGFR monoclonal antibodies in metastatic and recurrent anal squamous cell carcinoma. Expert Rev Anticancer Ther. 2020 Aug 15;: Authors: Rogers JE, Jácome AA, Ohinata A, Wolff R, Morris VK, Johnson B, Mehdizadeh A, Rothschild ND, Ahmed SU, Guerra JL, Eng C Abstract OBJECTIVES: Metastatic squamous cell carcinoma anal cancer (SCCA) is rare. Prospective data recommends front-line platinum doublet combinations...
Rare Cancers
Tue Aug 18, 2020 15:09
Needles in a haystack: Extremely rare invasive fungal infections reported in FungiScope® - Global Registry for Emerging Fungal Infections.
Related Articles Needles in a haystack: Extremely rare invasive fungal infections reported in FungiScope® - Global Registry for Emerging Fungal Infections. J Infect. 2020 Aug 13;: Authors: Salmanton-GarcÍa J, Koehler P, Kindo A, Falces-Romero I, GarcÍa-RodrÍguez J, RÁČil Z, Chen SC, Klimko N, Desoubeaux G, Thompson IGR, BenÍtez-PeÑuela MÁ, RodrÍguez JY, Sheppard DC, Hoenigl M, Govic YL, Badali H, Baddley JW, Chander J, Ingram PR, Pakstis DL, Mellinghoff SC, Atici...
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Tue Aug 18, 2020 13:16
Unrecognized tibial nerve injury in total-ankle arthroplasty: Two case reports.
Related Articles Unrecognized tibial nerve injury in total-ankle arthroplasty: Two case reports. Medicine (Baltimore). 2020 Jul 31;99(31):e21474 Authors: Lee GW, Lee KB Abstract RATIONALE: Tibial nerve injury is a sustainable but rare complication during total-ankle arthroplasty (TAA). We outlined 2 previously unreported cases of tibial nerve injury in TAA, including the prognoses and possible causes. PATIENT CONCERNS: First, a 63-year-old...
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Tue Aug 18, 2020 13:16
[Diagnosis and treatment of basal cell carcinoma : A question of the risk of recurrence].
Related Articles [Diagnosis and treatment of basal cell carcinoma : A question of the risk of recurrence]. Hautarzt. 2020 Aug;71(8):580-587 Authors: Lang BM, Grabbe S Abstract Basal cell carcinoma is the most common type of cancer in Central Europe and has a high medical relevance. Due to its high tendency of recurrence, an important parameter in the planning of therapy is the risk of recurrence. After clinical and histological diagnosis, the...
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Tue Aug 18, 2020 13:16
Removal of Double Cavernous Angioma of the Frontal Lobe using a Three-Dimensional Printed Model: A Case Report.
Related Articles Removal of Double Cavernous Angioma of the Frontal Lobe using a Three-Dimensional Printed Model: A Case Report. J UOEH. 2020;42(2):217-222 Authors: Umemura T, Nishizawa S, Miyachi H, Yamamoto J Abstract Cerebral cavernous angiomas are vascular anomalies with dilated spaces. We report the case of rare double cavernous angiomas causing higher brain dysfunction. A 74-year-old man exhibited cognitive dysfunction. Magnetic resonance...
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Tue Aug 18, 2020 13:16
Pneumothorax and the biology of Birt-Hogg-Dubé syndrome.
Related Articles Pneumothorax and the biology of Birt-Hogg-Dubé syndrome. Thorax. 2020 06;75(6):442-443 Authors: Marciniak SJ, Johnson SR PMID: 32414881 [PubMed - indexed for MEDLINE]
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Tue Aug 18, 2020 13:16
[Full thickness resection of a pyloric adenoma in the proximal duodenum in a 67-year-old patient with attenuated polyposis coli].
Related Articles [Full thickness resection of a pyloric adenoma in the proximal duodenum in a 67-year-old patient with attenuated polyposis coli]. Z Gastroenterol. 2020 Aug;58(8):767-772 Authors: Anliker O, Sieweke W, Töpfer A, Wülker I, Breidert M Abstract BACKGROUND:  Pyloric gland adenomas (PGAs) are very rare and underdiagnosed, mostly be founded in the stomach. Similar to colorectal adenomas they have a high risk of malignant transformation...
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Tue Aug 18, 2020 13:16
A novel germline BMPR1A variant (c.72_73delGA) in a Japanese family with hereditary mixed polyposis syndrome.
Related Articles A novel germline BMPR1A variant (c.72_73delGA) in a Japanese family with hereditary mixed polyposis syndrome. Jpn J Clin Oncol. 2020 Jul 09;50(7):826-829 Authors: Miyahara Y, Ishida H, Kawabe K, Eto H, Kasai T, Ito T, Kaneko K, Arai M, Kamae N, Momose S, Eguchi H, Okazaki Y Abstract Hereditary mixed polyposis syndrome (HMPS) is a rare autosomal dominant disorder characterized by a mixture of typical and/or atypical juvenile...
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Tue Aug 18, 2020 13:16
In-depth characterization of the tumor microenvironment in central nervous system lymphoma reveals implications for immune-checkpoint therapy.
Related Articles In-depth characterization of the tumor microenvironment in central nervous system lymphoma reveals implications for immune-checkpoint therapy. Cancer Immunol Immunother. 2020 Sep;69(9):1751-1766 Authors: Marcelis L, Antoranz A, Delsupehe AM, Biesemans P, Ferreiro JF, Debackere K, Vandenberghe P, Verhoef G, Gheysens O, Cattoretti G, Bosisio FM, Sagaert X, Dierickx D, Tousseyn T Abstract Primary central nervous system lymphoma...
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Tue Aug 18, 2020 13:16
Association of fludarabin, cytarabine, and fractioned gemtuzumab followed by hematopoietic stem cell transplantation for first-line refractory acute myeloid leukemia in children: A single-center experience.
Related Articles Association of fludarabin, cytarabine, and fractioned gemtuzumab followed by hematopoietic stem cell transplantation for first-line refractory acute myeloid leukemia in children: A single-center experience. Pediatr Blood Cancer. 2020 06;67(6):e28305 Authors: Penel-Page M, Plesa A, Girard S, Marceau-Renaut A, Renard C, Bertrand Y Abstract CONTEXT: Acute myeloid leukemia (AML) is a rare disease in children, with only 50% to 60%...
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Tue Aug 18, 2020 13:16
Multicystic and diffuse malignant peritoneal mesothelioma in children.
Related Articles Multicystic and diffuse malignant peritoneal mesothelioma in children. Pediatr Blood Cancer. 2020 06;67(6):e28286 Authors: Vermersch S, Arnaud A, Orbach D, Andre N, Berger C, Kepenekian V, Brigand C, Fresneau B, Poli-Merol ML, Habougit C, Varlet F, Scalabre A Abstract BACKGROUND: Malignant and multicystic peritoneal mesotheliomas are extremely rare tumors in children, developing from mesothelial cells. No specific guidelines...
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Tue Aug 18, 2020 13:16
Mesenchymal folliculin is required for alveolar development: implications for cystic lung disease in Birt-Hogg-Dubé syndrome.
Related Articles Mesenchymal folliculin is required for alveolar development: implications for cystic lung disease in Birt-Hogg-Dubé syndrome. Thorax. 2020 06;75(6):486-493 Authors: Chu L, Luo Y, Chen H, Miao Q, Wang L, Moats R, Wang T, Kennedy JC, Henske EP, Shi W Abstract BACKGROUND: Pulmonary cysts and spontaneous pneumothorax are presented in most patients with Birt-Hogg-Dubé (BHD) syndrome, which is caused by loss of function mutations...
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Tue Aug 18, 2020 13:16
Right atrial catheter "ghost" removal by cardiac surgery: A pediatric case series report.
Related Articles Right atrial catheter "ghost" removal by cardiac surgery: A pediatric case series report. Pediatr Blood Cancer. 2020 06;67(6):e28197 Authors: Massardier C, Perron J, Chetaille P, Côté JM, Drolet C, Houde C, Vaujois L, Naccache L, Michon B, Jacques F Abstract Fibrin sheath formation around long-term indwelling central venous catheters is common and usually benign. Fibrin sheath can persist after catheter removal and rarely leads...
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Tue Aug 18, 2020 13:16
Liver metastasis at diagnosis in children with nephroblastoma enrolled in SIOP2001 protocol: A French multicentric study.
Related Articles Liver metastasis at diagnosis in children with nephroblastoma enrolled in SIOP2001 protocol: A French multicentric study. Pediatr Blood Cancer. 2020 06;67(6):e28201 Authors: Liné A, Sudour-Bonnange H, Languillat-Fouquet V, Brisse H, Irtan S, Verschuur A, Sarnacki S, Thébaud E, Coulomb-L'Hermine A, Notz-Carrère A, Michon J, Tabone MD, Boulanger C, Pellier I, Freycon C, Audry G, Dijoud F, Morelle M, Bergeron C, Pasqualini C Abstract ...
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Tue Aug 18, 2020 13:16
FLCN-regulated miRNAs suppressed reparative response in cells and pulmonary lesions of Birt-Hogg-Dubé syndrome.
Related Articles FLCN-regulated miRNAs suppressed reparative response in cells and pulmonary lesions of Birt-Hogg-Dubé syndrome. Thorax. 2020 06;75(6):476-485 Authors: Min H, Ma D, Zou W, Wu Y, Ding Y, Zhu C, Lin A, Song S, Liang Q, Chen B, Zhang B, Wan Y, Ye M, Pan Y, Wen Y, Yi L, Gao Q Abstract BACKGROUND: Birt-Hogg-Dubé Syndrome (BHDS) characterised by skin fibrofolliculomas, kidney tumour and pulmonary cysts/pneumothorax is caused by...
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Tue Aug 18, 2020 13:16
Familial intracranial ependymoma mimicking an extra-lesion: A case report and review of the literature.
Related Articles Familial intracranial ependymoma mimicking an extra-lesion: A case report and review of the literature. J Clin Neurosci. 2020 Apr;74:250-253 Authors: Chen BY, Praeger A, Christie M, Yuen T Abstract Familial occurrence of intracranial ependymoma, in the absence of neurofibromatosis type 2 (NF2), is very rare with only a few cases reported in the literature. We report a 62-year-old man, who presented with a posterior fossa ependymoma...
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Tue Aug 18, 2020 13:16
Management of Unresectable Metastatic Primitive Myxoid Mesenchymal Tumor of Infancy: A Case Report and Systematic Review of the Literature.
Related Articles Management of Unresectable Metastatic Primitive Myxoid Mesenchymal Tumor of Infancy: A Case Report and Systematic Review of the Literature. J Pediatr Hematol Oncol. 2020 04;42(3):163-169 Authors: Asaftei SD, Campello A, Tirtei E, Colombo S, Vallero S, Boffano M, Fagioli F Abstract Primitive myxoid mesenchymal tumor of infancy is a rare soft tissue tumor. The present case is one of the most invasive primitive myxoid mesenchymal...
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Tue Aug 18, 2020 13:16
Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody.
Related Articles Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody. Cell. 2020 03 05;180(5):878-894.e19 Authors: Singh M, Jackson KJL, Wang JJ, Schofield P, Field MA, Koppstein D, Peters TJ, Burnett DL, Rizzetto S, Nevoltris D, Masle-Farquhar E, Faulks ML, Russell A, Gokal D, Hanioka A, Horikawa K, Colella AD, Chataway TK, Blackburn J, Mercer TR, Langley DB, Goodall DM, Jefferis R, Gangadharan Komala M, Kelleher AD, Suan D,...
Rare Cancers
Tue Aug 18, 2020 13:16
Treatment patterns and outcomes for pancreatic tumors in children: an analysis of the National Cancer Database.
Related Articles Treatment patterns and outcomes for pancreatic tumors in children: an analysis of the National Cancer Database. Pediatr Surg Int. 2020 Mar;36(3):357-363 Authors: Picado O, Ferrantella A, Zabalo C, Rao K, Thorson CM, Sola JE, Perez EA Abstract PURPOSE: Pancreatic tumors are rare in children and limited data are available regarding incidence, treatment, and outcomes. We aim to describe patient and tumor characteristics and to...
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Tue Aug 18, 2020 13:16
Autoimmune polyradiculitis due to combination immunotherapy with ipilimumab and nivolumab for the treatment of metastatic melanoma.
Related Articles Autoimmune polyradiculitis due to combination immunotherapy with ipilimumab and nivolumab for the treatment of metastatic melanoma. J Clin Neurosci. 2020 Apr;74:240-241 Authors: Lasocki A, Smith K Abstract Immune checkpoint inhibitors, also known as immunotherapy, have revolutionised the treatment of metastatic melanoma, but are frequently associated with immune-related adverse events (irAEs) affecting a variety of organ systems....
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Tue Aug 18, 2020 13:16
Preputial gland adenoma in a wild nutria (Myocastor coypus): a case report.
Related Articles Preputial gland adenoma in a wild nutria (Myocastor coypus): a case report. J Vet Sci. 2020 Jan;21(1):e1 Authors: Kong JY, Kim HS, Yeon SC, Park JK, Jeong KS, Hong IH Abstract Tumor incidence in wild mammals is reportedly very low. Wild nutria, a large rodent, is known to carry many infectious diseases, but rarely exhibits neoplastic diseases. We necropsied a male wild nutria and found a large nodular mass in the left inguinal...
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Tue Aug 18, 2020 13:16
Ectopic thymoma: Retrospective analysis of eight cases with clinical features and computed tomography findings.
Related Articles Ectopic thymoma: Retrospective analysis of eight cases with clinical features and computed tomography findings. Clin Imaging. 2020 Apr;60(2):153-159 Authors: Zhou Q, Han L, Ke X, Zhou J Abstract OBJECTIVE: To analyze the computed tomography (CT) and clinical features of ectopic thymoma, and to be familiar with the CT diagnosis of this disease. MATERIALS AND METHODS: CT data, clinical data, and pathological data of...
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Tue Aug 18, 2020 13:16
Epineural glomus tumor of the posterior interosseous nerve: Case report.
Related Articles Epineural glomus tumor of the posterior interosseous nerve: Case report. J Clin Neurosci. 2020 Apr;74:232-234 Authors: Drabent P, Bielle F, Bernat I, Peyre M Abstract Among peripheral nerve sheath tumors, epineural glomus tumors represent a rare differential diagnosis for peripheral nerve schwannoma, displaying the same appearance on MRI. Here we present the case of a 68-year-old man complaining of pain in the left forearm,...
Rare Cancers
Tue Aug 18, 2020 13:16
Multicentric Castleman Disease as a Rare Cause of Diffuse Lung Cysts.
Related Articles Multicentric Castleman Disease as a Rare Cause of Diffuse Lung Cysts. Am J Respir Crit Care Med. 2020 05 15;201(10):1292-1293 Authors: Peng M, Shi J, Feng R PMID: 31914318 [PubMed - indexed for MEDLINE]
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Tue Aug 18, 2020 13:16
Cardiac Calcified Amorphous Tumor as a Rare Cause of Ischemic Stroke: Clinical Case.
Related Articles Cardiac Calcified Amorphous Tumor as a Rare Cause of Ischemic Stroke: Clinical Case. Circ Cardiovasc Imaging. 2020 01;13(1):e009623 Authors: Formelli B, Farina A, Pescini F, Palumbo V, Grazia D'Alfonso M, Oddo A, Mori F, Poggesi A PMID: 31906700 [PubMed - indexed for MEDLINE]
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Tue Aug 18, 2020 13:16
Primary Tumor Infiltration and Severe Acute Kidney Injury in Patients with Acute Myeloblastic Leukemia.
Related Articles Primary Tumor Infiltration and Severe Acute Kidney Injury in Patients with Acute Myeloblastic Leukemia. J Nippon Med Sch. 2020 Mar 11;87(1):43-48 Authors: Aratani S, Aburakawa S, Ryotokuji T, Marumo A, Sakai Y, Inokuchi K, Tsuruoka S Abstract In patients with hematologic malignancies, acute kidney injury (AKI) is the most common kidney complication requiring nephrologist consultation. Although the causes of AKI are multifactorial,...
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Tue Aug 18, 2020 13:16
Updates in Novel Therapies for Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN).
Related Articles Updates in Novel Therapies for Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN). Curr Hematol Malig Rep. 2019 12;14(6):515-522 Authors: Economides MP, Rizzieri D, Pemmaraju N Abstract PURPOSE OF REVIEW: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, clinically aggressive hematologic malignancy that has heterogeneous presentation and can involve the skin, lymph nodes, and bone marrow. Recent advancements...
Rare Cancers
Tue Aug 18, 2020 13:16
Pediatric Nasopharyngeal Carcinoma: A Rare Tumor in a Developing Country-What Do We Learn?
Related Articles Pediatric Nasopharyngeal Carcinoma: A Rare Tumor in a Developing Country-What Do We Learn? J Pediatr Hematol Oncol. 2020 04;42(3):e140-e146 Authors: Zekri W, Wahed MA, Attia E, Khalil E Abstract BACKGROUND/AIM: Nasopharyngeal carcinoma (NPC) is rare in children, accounting for 1% of pediatric malignancies. The 5-fluorouracil Cisplatin regimen could be considered as a standard of care induction chemotherapy followed by concomitant...
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Tue Aug 18, 2020 13:16
Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness.
Related Articles Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness. Cancer Res. 2020 02 01;80(3):624-638 Authors: Patel VL, Busch EL, Friebel TM, Cronin A, Leslie G, McGuffog L, Adlard J, Agata S, Agnarsson BA, Ahmed M, Aittomäki K, Alducci E, Andrulis IL, Arason A, Arnold N, Artioli G, Arver B, Auber B, Azzollini J, Balmaña J, Barkardottir RB, Barnes DR, Barroso A, Barrowdale D, Belotti M, Benitez J, Bertelsen B,...
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Tue Aug 18, 2020 13:16
Unilateral Submandibular Gland Aplasia Mimicking Nodal Metastasis.
Related Articles Unilateral Submandibular Gland Aplasia Mimicking Nodal Metastasis. J Pediatr Hematol Oncol. 2020 04;42(3):220-221 Authors: Kandemirli SG Abstract Aplasia of salivary glands is rare and usually involves several major salivary glands. Isolated unilateral submandibular gland aplasia or aplasia accompanied by hypertrophy of contralateral submandibular gland or sublingual glands is a rare entity. The majority of cases are incidentally...
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Tue Aug 18, 2020 13:16
Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia.
Related Articles Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia. Blood Adv. 2019 10 22;3(20):3157-3169 Authors: Shiba N, Yoshida K, Hara Y, Yamato G, Shiraishi Y, Matsuo H, Okuno Y, Chiba K, Tanaka H, Kaburagi T, Takeuchi M, Ohki K, Sanada M, Okubo J, Tomizawa D, Taki T, Shimada A, Sotomatsu M, Horibe K, Taga T, Adachi S, Tawa A, Miyano S, Ogawa S, Hayashi Y Abstract ...
Rare Cancers
Tue Aug 18, 2020 13:16
Clinical presentation, management and follow-up of 83 patients with Leydig cell tumors of the testis: a prospective case-cohort study.
Related Articles Clinical presentation, management and follow-up of 83 patients with Leydig cell tumors of the testis: a prospective case-cohort study. Hum Reprod. 2019 08 01;34(8):1389-1403 Authors: Pozza C, Pofi R, Tenuta M, Tarsitano MG, Sbardella E, Fattorini G, Cantisani V, Lenzi A, Isidori AM, Gianfrilli D, TESTIS UNIT Abstract STUDY QUESTION: When should 'not so rare' Leydig cell tumors (LCTs) of the testis be suspected, diagnosed,...
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Tue Aug 18, 2020 13:16
Small Bowel Adenocarcinoma, Version 1.2020, NCCN Clinical Practice Guidelines in Oncology.
Related Articles Small Bowel Adenocarcinoma, Version 1.2020, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2019 09 01;17(9):1109-1133 Authors: Benson AB, Venook AP, Al-Hawary MM, Arain MA, Chen YJ, Ciombor KK, Cohen SA, Cooper HS, Deming DA, Garrido-Laguna I, Grem JL, Hoffe SE, Hubbard J, Hunt S, Kamel A, Kirilcuk N, Krishnamurthi S, Messersmith WA, Meyerhardt J, Miller ED, Mulcahy MF, Nurkin S, Overman MJ, Parikh A, Patel H, Pedersen...
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Tue Aug 18, 2020 13:16
Small Bowel Adenocarcinoma: Etiology, Presentation, and Molecular Alterations.
Related Articles Small Bowel Adenocarcinoma: Etiology, Presentation, and Molecular Alterations. J Natl Compr Canc Netw. 2019 09 01;17(9):1135-1141 Authors: Pedersen KS, Raghav K, Overman MJ Abstract Small bowel adenocarcinoma (SBA) is a rare cancer that has been treated similarly to colorectal cancer (CRC) in the advanced setting. Incidence has been increasing as detection efforts have been improving for these challenging-to-diagnose tumors,...
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Tue Aug 18, 2020 13:16
Preventing Measles in Immunosuppressed Cancer and Hematopoietic Cell Transplantation Patients: A Position Statement by the American Society for Transplantation and Cellular Therapy.
Related Articles Preventing Measles in Immunosuppressed Cancer and Hematopoietic Cell Transplantation Patients: A Position Statement by the American Society for Transplantation and Cellular Therapy. Biol Blood Marrow Transplant. 2019 11;25(11):e321-e330 Authors: Pergam SA, Englund JA, Kamboj M, Gans HA, Young JH, Hill JA, Savani B, Chemaly RF, Dadwal SS, Storek J, Duchin J, Carpenter PA Abstract Until recently, measles exposures were relatively...
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Tue Aug 18, 2020 13:16
Analyses of molecular and histopathologic features and expression of PRAME by immunohistochemistry in mucosal melanomas.
Related Articles Analyses of molecular and histopathologic features and expression of PRAME by immunohistochemistry in mucosal melanomas. Mod Pathol. 2019 12;32(12):1727-1733 Authors: Toyama A, Siegel L, Nelson AC, Najmuddin M, Bu L, LaRue R, Henzler C, Caicedo-Granados E, Giubellino A, Li F Abstract Mucosal melanomas are rare, and less is known about the biomarkers of this subtype in comparison to cutaneous or uveal melanomas. Preferentially...
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Tue Aug 18, 2020 13:16
Molecular characterization of gastric-type endocervical adenocarcinoma using next-generation sequencing.
Related Articles Molecular characterization of gastric-type endocervical adenocarcinoma using next-generation sequencing. Mod Pathol. 2019 12;32(12):1823-1833 Authors: Garg S, Nagaria TS, Clarke B, Freedman O, Khan Z, Schwock J, Bernardini MQ, Oza AM, Han K, Smith AC, Stockley TL, Rouzbahman M Abstract Gastric-type endocervical adenocarcinoma is an uncommon aggressive type of endocervical adenocarcinoma that is not associated with human papillomavirus...
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Tue Aug 18, 2020 13:16
Successful Intensive Care Treatment of Severe Lactic Acidosis and Tumor Lysis Syndrome Related to Intravascular Lymphoma.
Related Articles Successful Intensive Care Treatment of Severe Lactic Acidosis and Tumor Lysis Syndrome Related to Intravascular Lymphoma. J Nippon Med Sch. 2020 Mar 11;87(1):32-36 Authors: Mase H, Ogawa Y, Takeuchi J, Genda Y, Ichiba S, Sakamoto A Abstract Intravascular lymphoma is a rare disease that progresses to multiple organ dysfunction caused primarily by tumor cell proliferation in small blood vessels. Few studies have investigated...
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Tue Aug 18, 2020 13:16
Absence of H3F3A mutation in a subset of malignant giant cell tumor of bone.
Related Articles Absence of H3F3A mutation in a subset of malignant giant cell tumor of bone. Mod Pathol. 2019 12;32(12):1751-1761 Authors: Yoshida KI, Nakano Y, Honda-Kitahara M, Wakai S, Motoi T, Ogura K, Sano N, Shibata T, Okuma T, Iwata S, Kawai A, Ichimura K, Yoshida A Abstract Giant cell tumor of bone typically involves the epiphysis of the long bones of skeletally mature patients. It is genetically characterized by highly recurrent and...
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Tue Aug 18, 2020 13:16
Bone Marrow Necrosis in a Patient Following Blinatumomab Therapy.
Related Articles Bone Marrow Necrosis in a Patient Following Blinatumomab Therapy. J Pediatr Hematol Oncol. 2020 04;42(3):e167-e169 Authors: Yarali N, Isik M, Arman-Bilir O, Guzelkucuk Z, Oguz-Erdogan AS Abstract Bone marrow necrosis (BMN) is an extremely rare condition characterized by necrosis of the myeloid tissue and medullary stroma leaving an amorphous eosinophilic background and ill-defined necrotic cells in the hematopoietic bone marrow....
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Tue Aug 18, 2020 13:16
Management Strategies for Early-Onset Pulmonary Events Associated with Brigatinib.
Related Articles Management Strategies for Early-Onset Pulmonary Events Associated with Brigatinib. J Thorac Oncol. 2019 09;14(9):1547-1555 Authors: Camidge DR, Pabani A, Miller RM, Rizvi NA, Bazhenova L Abstract INTRODUCTION: Rare cases of early-onset pulmonary events (EOPEs) occurring within days of the start of administration of brigatinib have been reported (incidence 3%-6% with use of the recommended dose of 90 mg for 7 days and then a...
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Tue Aug 18, 2020 13:16
Plasma Cell Myeloma Type Posttransplant Lymphoproliferative Disorder in an 18-Month-Old Heart Transplant Recipient: Case Report and Review of the Literature.
Related Articles Plasma Cell Myeloma Type Posttransplant Lymphoproliferative Disorder in an 18-Month-Old Heart Transplant Recipient: Case Report and Review of the Literature. J Pediatr Hematol Oncol. 2020 04;42(3):e170-e173 Authors: Xue L, Zuppan C, Wang T, Kheradpour A, Rowsell EH, Wang J Abstract Plasma cell myeloma type posttransplant lymphoproliferative disorder (PTLD) is a rare subtype of monomorphic B-cell/plasmacytic-type PTLD. Only...
Rare Cancers
Tue Aug 18, 2020 13:16
Presacral Medulloepithelioma: Case Report and Literature Review.
Related Articles Presacral Medulloepithelioma: Case Report and Literature Review. J Pediatr Hematol Oncol. 2020 04;42(3):244-247 Authors: Honnorat M, Al-Karmi S, Hawkins C, Johnston D, Gerstle T, Schechter T, Huang A, Bouffet E Abstract Medulloepithelioma is a rare early childhood tumor typically presenting in the intraocular region and neuroaxis. We report a rare case of a 2-year-old girl that presented with a peripheral medulloepithelioma...
Rare Cancers
Tue Aug 18, 2020 13:16
Osteopoikilosis With Germline LEMD3 Mutation Mimicking Bone Metastases in a Girl With a Concurrent Secreting Mixed Germ Cell Tumor.
Related Articles Osteopoikilosis With Germline LEMD3 Mutation Mimicking Bone Metastases in a Girl With a Concurrent Secreting Mixed Germ Cell Tumor. J Pediatr Hematol Oncol. 2020 04;42(3):e185-e187 Authors: Correa Llano MG, Mora J, Torner F, Inarejos E, Cruz O Abstract Osteopoikilosis (OPK) is a rare, benign, asymptomatic bone disease causing dense bone lesions, which could be interpreted as bone metastasis. The symmetric distribution, lack...
Rare Cancers
Tue Aug 18, 2020 13:16
Cancer events in Belgian nursing home residents: An EORTC prospective cohort study.
Related Articles Cancer events in Belgian nursing home residents: An EORTC prospective cohort study. J Geriatr Oncol. 2019 09;10(5):805-810 Authors: Wildiers H, Mauer M, Elseviers M, De Wolf J, Hatse S, Hamaker M, Buntinx F, De Lepeleire J, Uytterschaut G, Falandry C, Tryfonidis K, Janssen-Heijnen M Abstract OBJECTIVES: This prospective multicenter cohort study aimed to describe new cancer events in nursing home residents (NHR). MATERIALS...
Rare Cancers
Tue Aug 18, 2020 13:16
Circumportal pancreas.
Related Articles Circumportal pancreas. J Visc Surg. 2019 Oct;156(5):467-468 Authors: Addeo P, Locicero A, Bachellier P Abstract The circumportal pancreas (CPP) is a normal though rare anatomical variant of the pancreas resulting from fusion of ventral and dorsal pancreatic buds during embryogenesis. Preoperative imaging in a 69-year-old man displayed the presence of a CPP completely encasing the portal vein. For pancreatic resection, missing...
Rare Cancers
Tue Aug 18, 2020 13:16
Chemoport-related Fungemia Caused by Trichosporon asahii.
Related Articles Chemoport-related Fungemia Caused by Trichosporon asahii. J Pediatr Hematol Oncol. 2020 04;42(3):e193-e194 Authors: Raju DS, Sugunan A, Keechilattu P, Philip A, Reghu R Abstract Trichosporon asahii is a rare opportunistic fungal pathogen that causes fatal systemic infection in immunocompromised patients. Neutropenia developing due to malignancies is an important risk factor for fungal infection. Invasive infections due to T....
Rare Cancers
Tue Aug 18, 2020 13:16
Multimodal Management of Congenital Orbital Malignant Rhabdoid Tumor: Review of Literature and Report of a Rare Case.
Related Articles Multimodal Management of Congenital Orbital Malignant Rhabdoid Tumor: Review of Literature and Report of a Rare Case. J Pediatr Hematol Oncol. 2020 04;42(3):228-233 Authors: Biswas A, Kumar R, Bakhshi S, Sen S, Sharma MC Abstract BACKGROUND: Malignant rhabdoid tumor (MRT) is a rare and aggressive tumor with a dismal prognosis. It commonly arises in the brain (65%), soft tissues (26%), and the kidney (9%). Primary orbital involvement...
Rare Cancers
Tue Aug 18, 2020 13:16
Monitoring circulating tumor cells in vivo by a confocal microscopy system.
Related Articles Monitoring circulating tumor cells in vivo by a confocal microscopy system. Cytometry A. 2019 06;95(6):657-663 Authors: Hu Y, Tang W, Cheng P, Zhou Q, Tian X, Wei X, He H Abstract Circulating tumor cells (CTCs) play a key role in cancer metastasis but are very difficult to detect. in vivo monitoring CTCs has been recognized as an important technique for cancer research and clinical diagnosis. Recently, a noninvasive method,...
Rare Cancers
Tue Aug 18, 2020 13:16
Anaplastic Astrocytoma in a Child With Coffin-Siris Syndrome and a Germline SMARCE1 Mutation: A Case Report.
Related Articles Anaplastic Astrocytoma in a Child With Coffin-Siris Syndrome and a Germline SMARCE1 Mutation: A Case Report. J Pediatr Hematol Oncol. 2020 04;42(3):e177-e180 Authors: Lin B, Kesserwan C, Quinn EA, Einhaus SL, Wright KD, Azzato EM, Orr BA, Upadhyaya SA Abstract Coffin-Siris syndrome (CSS) is a rare congenital disorder with variable clinical phenotype consisting of developmental delay and characteristic facial features. It is...
Rare Cancers
Tue Aug 18, 2020 13:16

Hand Mirror Cells and Hypercalcemia: A Rare Presentation of Pediatric Acute Lymphoblastic Leukemia.
Related Articles Hand Mirror Cells and Hypercalcemia: A Rare Presentation of Pediatric Acute Lymphoblastic Leukemia. J Pediatr Hematol Oncol. 2020 04;42(3):e181-e184 Authors: Cacciotti C, Leber B, Cox S, Arredondo J, Bassilious E, Athale U Abstract Hand mirror cell (HMC) leukemia is a variant of acute lymphoblastic leukemia previously described in the adult population where lymphoblasts manifest distinctive hand mirror morphologic features....
Rare Cancers
Tue Aug 18, 2020 13:16

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