Objective The goal of this study was to examine sex differences in tau distribution across the brain of older adults, using positron emission tomography (PET), and investigate how these differences might associate with cognitive trajectories. Methods Participants were 343 clinically‐normal individuals (Female,58%; 73.8[8.5] years) and 55 individuals with MCI (Female,38%; 76.9[7.3] years) from the Harvard Aging Brain Study and the Alzheimer's Disease Neuroimaging Initiative. We examined 18F‐Flortaucipir...
Objective The longitudinal association of blood biomarkers of total tau (t‐tau), neurofilament light (Nf‐L), and glial fibrillary acidic protein (GFAP) with common sporadic AD and cognitive decline are not established. Methods Using a single molecule array technology, ultrasensitive immunoassays for serum concentrations of total tau (t‐tau), neurofilament light (Nf‐L), and glial fibrillary acidic protein (GFAP) were measured in a population sample of 1,327 participants (60% African Americans...
In multiple sclerosis (MS), a subset of chronic active white matter lesions are identifiable on MRI by their paramagnetic rims, and increasing evidence supports their association with clinical disease severity. Here we study their potential role in differential diagnosis, screening an international multicenter clinical research‐based sample of 438 individuals affected by different neurological conditions (MS, other inflammatory, infectious, and non‐inflammatory). Paramagnetic rim lesion detection,...
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Publication date: Available online 15 August 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Mohamed Macki, Hesham Mostafa Zakaria, Lara W Massie, Jaafar Elmenini, Mohamed Fakih, Belal Dakroub, Victor Chang
Publication date: November 2020Source: Clinical Neurology and Neurosurgery, Volume 198Author(s): Ranjit Ganguly, Amy Minnema, Varun Singh, Andrew Grossbach
Publication date: Available online 14 August 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): Joshua H. Weinberg, Ahmad Sweid, Kalyan Sajja, Rawad Abbas, Ashlee Asada, Osman Kozak, Larami Mackenzie, Hana Choe, Michael Reid Gooch, Nabeel Herial, Stavropoula Tjoumakaris, Hekmat Zarzour, Robert H. Rosenwasser, Pascal Jabbour
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Abstract The locomotor networks in the spinal cord coordinate muscle contractions and govern limb movements, ensuring postural body stability and smooth locomotion at different speeds. Dissecting the organization and connection of spinal motor networks is crucial to interpret their functional roles and thus can help to design more specific interventions for motor system diseases. Traditional two‐dimensional (2D) histological sectioning is inadequate to accurately dissect complex architecture of...
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Recent studies have shown that neural stimulation can be used to provide artificial sensory feedback to amputees eliciting sensations referred on the amputated hand. The temporal properties of the neural stimu...
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J Neurol Surg Rep 2020; 81: e46-e51DOI: 10.1055/s-0040-1712919 Background We report an extremely unusual case of anterior clinoid process (ACP) metastasis as the first presentation of a signet ring cell carcinoma. Case Description A 54-year-old female patient presented with right-sided visual disturbances due to optic nerve compression from a computed tomography (CT)-identified right anterior clinoid bone lesion. Contrast-enhanced magnetic resonance imaging showed an extra-axial,...
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Publication date: Available online 15 August 2020Source: Journal of Neuroscience MethodsAuthor(s): Tianyu Jia, Ke Liu, Chao Qian, Chong Li, Linhong Ji
Publication date: Available online 15 August 2020Source: Journal of Neuroscience MethodsAuthor(s): Ayumu Konno, Hirokazu Hirai
Publication date: Available online 14 August 2020Source: Journal of Neuroscience MethodsAuthor(s): Sana Hannan, Mayo Faulkner, Kirill Aristovich, James Avery, Matthew C. Walker, David S. Holder
Publication date: Available online 14 August 2020Source: Journal of Neuroscience MethodsAuthor(s): Matthew Binder, Suzanne O. Nolan, Joaquin N. Lugo
Publication date: Available online 14 August 2020Source: Journal of Neuroscience MethodsAuthor(s): Valerij G. Kiselev
Publication date: Available online 14 August 2020Source: Journal of Neuroscience MethodsAuthor(s): Yimeng Ge, Shuan Ye, Kaihua Zhu, Tianruo Guo, Diansan Su, Dingguo Zhang, Yao Chen, Xinyu Chai, Xiaohong Sui
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Journal of Neurotrauma, Ahead of Print.
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Abstract Objective To compare the utility of constructive interference in steady-state (CISS) sequence over T2-weighted (T2W) sequence in the accurate delineation of the tethering element on magnetic resonance (MR) imaging in patients of tethered cord syndrome (TCS) and correlation with intraoperative findings. Methods MR findings of fifty-six consecutive...
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Publication date: Available online 16 August 2020Source: Brain Research BulletinAuthor(s): Wei-Bing Chen, Lian-Xiu Zhang, Yi-Kun Zhao, Jie Li, Yan Jiao
Publication date: Available online 13 August 2020Source: Brain Research BulletinAuthor(s): Fan Yang, Hai Zhao, Kaiyuan Zhang, Xiuying Wu, Hongtao Liu
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Publication date: Available online 15 August 2020Source: World NeurosurgeryAuthor(s): Ivan Lozada-Martínez, María Bolaño-Romero, Luis Moscote-Salazar, Daniela Torres-Llinas
Publication date: Available online 15 August 2020Source: World NeurosurgeryAuthor(s): Tim S. Yoon, Aaron J. Greenberg, Praveen V. Mummaneni, Weilong J. Shi
Publication date: Available online 15 August 2020Source: World NeurosurgeryAuthor(s): Garret P. Greeneway, Paul S. Page, Viharkumar Patel, Azam S. Ahmed
Publication date: November 2020Source: World Neurosurgery, Volume 143Author(s): Marcelo D. Vilela, Hugo AS. Pedrosa, Braulio F. Mesquita, Claudia L.F. Horiguchi
Publication date: November 2020Source: World Neurosurgery, Volume 143Author(s): Nitesh V. Patel, Deepak Khatri, Randy D'Amico, Madeline Abrams, Noah Reichman, Christopher G. Filippi, Todd Anderson, Fanni Ratzon, Tamika Wong, Sherese Fralin, Mona Li, Lukas Faltings, David J. Langer, John A. Boockvar
Publication date: November 2020Source: World Neurosurgery, Volume 143Author(s): Waleed Brinjikji, Harry J. Cloft, Kelly Flemming, Giuseppe Lanzino
Publication date: November 2020Source: World Neurosurgery, Volume 143Author(s): Yusuke Funakoshi, Tadahisa Shono, Ai Kurogi, Naoki Maehara, Nobuhiro Hata, Masahiro Mizoguchi
Publication date: November 2020Source: World Neurosurgery, Volume 143Author(s): Bharath Raju, Omar Ashraf, Fareed Jumah, Naveen Mandya Appaji Gowda, Gaurav Gupta, Hai Sun, Anil Nanda
Publication date: October 2020Source: World Neurosurgery, Volume 142Author(s): Deepak Khatri, Randy D'Amico, Amy Tucker, Madeline Abrams, David Langer, John Boockvar
Publication date: Available online 15 August 2020Source: World NeurosurgeryAuthor(s): Xiangyuan Cao, Yida Wang, Yi Jin
Publication date: Available online 15 August 2020Source: World NeurosurgeryAuthor(s): Ru Tang, Song Mao, Dawei Li, Haibo Ye, Weitian Zhang
Publication date: Available online 15 August 2020Source: World NeurosurgeryAuthor(s): Jian Guan, Chenghua Yuan, Can Zhang, Longbing Ma, Qingyu Yao, Lei Cheng, Zhenlei Liu, Kai Wang, Wanru Duan, Xingwen Wang, Hao Wu, Zan Chen, Fengzeng Jian
Publication date: Available online 15 August 2020Source: World NeurosurgeryAuthor(s): Nunthasiri Wittayanakorn, Vincent Diong Weng Nga, Mirna Sobana, Nor Faizal Ahmad Bahuri, Ronnie E. Baticulon
Publication date: Available online 15 August 2020Source: World NeurosurgeryAuthor(s): Eric Bozier, Alexandre Carpentier, Caroline Apra
Publication date: Available online 15 August 2020Source: World NeurosurgeryAuthor(s): Shota Kakizaki, Toshihiro Ishibashi, Naoki Kato, Issei Kan, Kengo Nishimura, Yuichi Murayama
Publication date: November 2020Source: World Neurosurgery, Volume 143Author(s): Saeed Kayhanian, Robert J. Machado
Publication date: October 2020Source: World Neurosurgery, Volume 142Author(s): Joshua D. Bernstock, Hannah E. Olsen, David Segar, Kevin Huang, Ari D. Kappel, Walid Ibn Essayed, Phillip L. Pearl, Joseph R. Madsen
Publication date: Available online 14 August 2020Source: World NeurosurgeryAuthor(s): Peter Lewkonia
Publication date: Available online 14 August 2020Source: World NeurosurgeryAuthor(s): John K. Houten, Samuel J. Swiggett, Bana Hadid, David M. Choueka, Merritt D. Kinon, Razvan Buciuc, Daniel W. Zumofen
Publication date: Available online 14 August 2020Source: World NeurosurgeryAuthor(s): Yueh-Hsin Lin, Isabella M. Young, Andrew K. Conner, Chad A. Glenn, Arpan R. Chakraborty, Cameron E. Nix, Michael Y. Bai, Vukshitha Dhanaraj, R. Dineth Fonseka, Jorge Hormovas, Onur Tanglay, Robert G. Briggs, Michael E. Sughrue
Publication date: Available online 14 August 2020Source: World NeurosurgeryAuthor(s): Clayton L. Rosinski, Mandana Behbahani, Brett Geever, Anisse N. Chaker, Saavan Patel, Ryan Chiu, Jack Zakrzewski, David Rosenberg, Rown Parola, Koral Shah, Ankit I. Mehta
Publication date: Available online 13 August 2020Source: World NeurosurgeryAuthor(s): Wanjin Qin, Peng Yang, Feng Zhou, Haiqing Mao, Huilin Yang
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