Publication date: Available online 15 August 2020Source: European Journal of Surgical OncologyAuthor(s): Minas Baltatzis, Maria Grazia Rodriquenz, Ajith K. Siriwardena, Nicola De Liguori Carino
Publication date: Available online 15 August 2020Source: European Journal of Surgical OncologyAuthor(s): Iain McPherson, Nicholas A. Bradley, Rohith Govindraj, Ewan D. Kennedy, Alan J. Kirk, Mohammed Asif
Publication date: Available online 15 August 2020Source: European Journal of Surgical OncologyAuthor(s): Laura Ruspi, Ferdinando Carlo Maria Cananzi, Federico Sicoli, Laura Samà, Salvatore Lorenzo Renne, Andrea Marrari, Nicolò Gennaro, Piergiuseppe Colombo, Luca Cozzaglio, Letterio Salvatore Politi, Alexia Bertuzzi, Vittorio Quagliuolo
Publication date: Available online 14 August 2020Source: European Journal of Surgical OncologyAuthor(s): Jia Ke, Xuan-hui Liu, Xiao-feng Jiang, Zhen He, Jian Xiao, Bin Zheng, Yu-feng Chen, Ze-rong Cai, Xiao-bin Zheng, Yi-feng Zou, Ping Lan, Xiao-jian Wu, Feng Gao
Publication date: September 2020Source: European Journal of Surgical Oncology, Volume 46, Issue 9Author(s):
Publication date: September 2020Source: European Journal of Surgical Oncology, Volume 46, Issue 9Author(s): Oktar Asoglu, Handan Tokmak, Baris Bakir, Gokhan Demir, Enis Ozyar, Banu Atalar, Suha Goksel, Burak Koza, Aslihan Guven Mert, Atakan Demir, Koray Guven
Publication date: September 2020Source: European Journal of Surgical Oncology, Volume 46, Issue 9Author(s): Wacław Hołówko, Ioannis Triantafyllidis, Maud Neuberg, Nicolas Tabchouri, Marc Beaussier, Mostefa Bennamoun, Anthony Sarran, Marine Lefevre, Christophe Louvet, Brice Gayet, David Fuks
Publication date: September 2020Source: European Journal of Surgical Oncology, Volume 46, Issue 9Author(s): Pabos Charalambous, Dimitrios Moris, Georgia-Sofia Karachaliou, Alexandros Papalampros, Nikolaos Dimitrokallis, Diamantis I. Tsilimigras, Dimitrios Oikonomou, Athanasios Petrou
Publication date: September 2020Source: European Journal of Surgical Oncology, Volume 46, Issue 9Author(s):
Publication date: September 2020Source: European Journal of Surgical Oncology, Volume 46, Issue 9Author(s):
Publication date: Available online 13 August 2020Source: European Journal of Surgical OncologyAuthor(s): Martin Hübner, Shigeki Kusamura, Laurent Villeneuve, Ahmed Al-Niaimi, Mohammad Alyami, Konstantin Balonov, John Bell, Robert Bristow, Delia Cortés Guiral, Anna Fagotti, Luiz Fernando R. Falcão, Olivier Glehen, Laura Lambert, Lloyd Mack, Tino Muenster, Pompiliu Piso, Marc Pocard, Beate Rau, Olivia Sgarbura, S.P. Somashekkar
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POLARIS: a prospective, multicenter, noninterventional study assessing palbociclib in hormone receptor-positive advanced breast cancer. Future Oncol. 2020 Aug 13;: Authors: Tripathy D, Blum JL, Rocque GB, Bardia A, Karuturi MS, Cappelleri JC, Liu Y, Zhang Z, Davis KL, Wang Y Abstract This report describes the rationale, purpose and design of the POLARIS study. POLARIS is an ongoing noninterventional, prospective, multicenter study. Female and...
Related Articles Clinical efficacy, predictive biomarkers and response patterns of immunotherapy combinations for patients with cancer. Future Oncol. 2020 Aug;16(23):1659-1664 Authors: Recondo G, Mezquita L PMID: 32783513 [PubMed - in process]
Related Articles Sorafenib treatment by Child-Pugh score in Latin American patients with hepatocellular carcinoma. Future Oncol. 2020 Aug 12;: Authors: de Guevara LL, Dagher L, Arruda VM, Nakajima K, Kudo M Abstract Aim: To evaluate sorafenib treatment in Latin American patients with unresectable hepatocellular carcinoma in the real-world GIDEON study. Patients and methods: Sorafenib administration, safety and efficacy were analyzed by Child-Pugh...
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Journal of Adolescent and Young Adult Oncology, Ahead of Print.
Journal of Adolescent and Young Adult Oncology, Ahead of Print.
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Abstract This study was aimed to analyze the readability and quality of patient education websites on esophageal cancer. Yahoo!, Google, and Bing search engines were searched using keywords esophageal cancer, esophageal tumor, esophageal tumor, esophageal malignancy, esophageal cancer, esophageal tumor, esophageal tumor, and esophageal malignancy. The first 50 websites resulting in each keyword search were evaluated using validated FRES, LIDA, and DISCERN scores to assess readability,...
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Colorectal cancer (CRC) is one of the causes of cancer-related death worldwide. The aim of our study was to disclose the expression pattern and underlying molecular mechanism of circular RNA TADA2A (circTADA2A...
Emerging evidence has shown that dysregulated expression of long noncoding RNAs (lncRNAs) is implicated in liver hepatocellular carcinoma (HCC). However, the role and molecular mechanism of differentially expr...
Chemoresistance is emerging as a major barrier to successful treatment in acute myeloid leukemia (AML), and evasion of apoptosis is among the fundamental underlying mechanisms. Therefore, unraveling molecular ...
Many cancer-associated single nucleotide polymorphisms (SNPs) are located in the genomic regions of long non-coding RNAs (lncRNAs). Mechanisms of these SNPs in connection to cancer risk are not fully understood.
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Abstract Sex‐determining region Y box (SOXs) are expressed in various cells and control cell fate and differentiation in a multitude of physiologic processes. SOX6, a main representative of SOXs, is involved in the regulation of carcinogenesis in various human malignancies. However, the role of SOX6 in clear cell renal cell carcinoma (ccRCC) remains unclear. In this study, SOX6 expression in ccRCC and its clinical significance were investigated. In vitro and in vivo assays were used to explore the...
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Abstract Purpose IGFBP2 is one of the highly expressed genes in glioblastoma (GBM). It has both IGF dependent and independent activities. IGF independent actions are mediated by the activation of integrin signalling through its RGD motif present at C-terminal domain. One of the actions of IGFBP2 is to regulate β-catenin by the inactivation of GSK3β, which preferentially accumulates in the cytoplasm. The mechanism of nuclear β-catenin...
Abstract Purpose Primary benign and malignant central nervous system (CNS) tumors are the most frequent solid tumors in the pediatric age and represent the leading cause of death by cancer in children in high income countries. However, information regarding specific causes of death in this population is still limited. The objective of this work was to investigate mortality in a large cohort of children diagnosed at our institution....
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Radiotherapy (RT) is applied in 45–60% of all cancer patients either alone or in multimodal therapy concepts comprising surgery, RT and chemotherapy. However, despite technical innovations approximately only 5...
Hepatocellular carcinoma (HCC) involving a major branch of the portal or hepatic vein is in a locally advanced stage and remains difficult to cure. This study aimed to evaluate the clinical effects of carbon i...
Patients with resected oral cavity squamous cell carcinoma (OCSCC) are often treated with adjuvant radiation (RT) ± concomitant chemotherapy based on pathological findings. Standard RT volumes include all surg...
We sought to investigate the prognostic impact of missed RT sessions in patients who had undergone surgery for oral cavity squamous cell carcinoma (OCSCC).
This study was an open-label, 2-arms, monocentric, randomized clinical trial comparing Xonrid®, a topical medical device, versus standard of care (SOC) in preventing and treating acute radiation dermatitis (AR...
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A consistent association between the visualization of tumor hypoxia and a poor outcome after curatively intended radiotherapy has been demonstrated[1]. On the initiative of the Danish Head and Neck Cancer Group (DAHANCA), imaging of hypoxia was investigated in the DAHANCA 24 trial (Clinical Trials.gov Identifier NCT01017224) to determine its prognostic value in patients with head and neck squamous cell carcinoma (HNSCC)[2]. During 2009-2011, 40 patients were prospectively included in the study irrespective...
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Publication date: September–October 2020Source: Reports of Practical Oncology & Radiotherapy, Volume 25, Issue 5Author(s): Orit Kaidar-Person, Icro Meattini, Douglas Zippel, Philip Poortmans
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Termination of protein biosynthesis is an essential step of gene expression, during which a complete functional protein is released from the ribosome. Premature or inefficient termination results in truncated, non-functional or toxic proteins that may cause disease. Indeed, more than 10% of human genetic diseases are caused by nonsense mutations leading to premature termination. Efficient and sensitive approaches are required to study eukaryotic termination mechanisms and to identify potential therapeutics...
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