Publication date: Available online 18 August 2020Source: American Journal of OtolaryngologyAuthor(s): Mahmoud Rouabhia, Marilou Piché, Marie-Noëlle Corriveau, Jamila Chakir
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Publication date: Available online 17 August 2020Source: Auris Nasus LarynxAuthor(s): Kenzo Ohara, Takeshi Kanaya, Yasuaki Harabuchi
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Background. Mucosa-associated lymphoid tissue (MALT) lymphomas are a subtype of non-Hodgkin lymphoma stemming from marginal zone B-cells. In this case report, we present two patients with an extremely rare localization of MALT lymphoma to the larynx. Methods. Case 1 is of a 78-year-old male presenting with a six-month history of progressive hoarseness with a past medical history significant for marginal zone lymphoma of the right orbit. Diagnosis was confirmed with a biopsy for extranodal marginal...
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ABSTRACT Pharyngeal pouch operations are commonly performed in ENT. However, some pouches can be large, with poor access making surgical management more complex.
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Conditions: Bronchial Carcinoma; Esophageal Carcinoma; Tumor of the Brain; Head and Neck Cancer; Pancreas Cancer; Sarcoma; Cervix Uteri CancerIntervention: Device: Fitness tracker based activity training for Arm A and B. Booklet "physical training, exercise and cancer" and an introduction about physical activity during cancer therapy for Arm A, B, CSponsor: University Hospital TuebingenRecruiting
Condition: Nasopharyngeal CarcinomaInterventions: Drug: Toripalimab; Radiation: IMRT to the nasopharynx and neck; Drug: Gemcitabine and Cisplatin Chemotherapy; Drug: Adjuvant chemotherapy with CapecitabineSponsors: Fudan University; Fudan University Eye and ENT Hospital; Anhui Provincial Hospital; Sir Run Run Shaw Hospital; Hangzhou Cancer Hospital; Ningbo Medical Center Lihuili Hospital; The First People's Hospital of Changzhou; Cancer Hospital of Chinese Academy of...
Conditions: Head and Neck Cancer; Intraoperative Complications; Coagulation Disorder, Blood; Vitamin K Deficiency; Thrombosis; Anticoagulants and Bleeding Disorders; Head and Neck Procedural ComplicationIntervention: Sponsor: Region SkaneNot yet recruiting
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Jeff Cobb had surgery for nasal polyposis 23 years ago and vowed he would never go through it again. “The...
Hyperparathyroidism occurs in people in every age group but is most common in patients in their 50s, 60s, and 70s....
Amber Luong, MD, PhD, a practicing rhinologist and research director in the Department of Otorhinolaryngology-Head and Neck Surgery at McGovern...
More than 100 physicians from around the world participated in ORL Frontiers first-ever virtual event, sponsored by the Department of...
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Abstract Background The aim of the study was to update our experience treating patients with glottic carcinoma in situ (CIS) with curative radiotherapy (RT). Methods Fifty patients received continuous‐course RT using once‐daily fractionation. Twenty‐eight (56%) had recurrent or persistent CIS after resection. Median total dose was 63.0 Gy; median dose per fraction was 2.25 Gy. Median follow‐up was 9.6 years for all patients and 8.4 years for survivors. Results After RT, 5 patients...
Abstract Consensus has yet to be reached on the optimal operation for patients with residual or recurrent nasopharyngeal carcinoma (NPC). To compare effectiveness and safety of open surgery and endoscopic surgery for patients with residual or recurrent NPC. Pubmed, Embase, and Cochrane were searched for relevant publications from January 1, 2000 to May 1, 2017. Included studies reported specific residual or local recurrent nasopharyngeal cancer survival data. Proportional meta‐analysis was performed...
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Related Articles The effect of dexamethasone on pain control after thyroid surgery: a meta-analysis of randomized controlled trials. Eur Arch Otorhinolaryngol. 2020 Aug 17;: Authors: Cheng L, Le Y, Yang H, Zhou X Abstract INTRODUCTION: The effect of dexamethasone on postoperative pain after thyroid surgery remains controversial. We conduct a systematic review and meta-analysis to explore the influence of dexamethasone versus placebo on postoperative...
Related Articles Depression profile in malignancy patients attending otorhinolaryngology clinic. Eur Arch Otorhinolaryngol. 2020 Aug 17;: Authors: Khadilkar MN, Pai KK, Rai T, Shenoy V, Dosemane D, Kabekkodu S Abstract PURPOSE: Patients with malignancy quite often suffer from physical as well as psychological symptoms due to the shattering diagnosis, and prolonged, incapacitating management. The frequency of the depressive disorder in malignancy...
Related Articles Individual variability of olfactory fMRI in normosmia and olfactory dysfunction. Eur Arch Otorhinolaryngol. 2020 Aug 14;: Authors: Yunpeng Z, Han P, Joshi A, Hummel T Abstract PURPOSE: The diagnosis of olfactory dysfunction is mainly based on psychophysical measurements. The aim of the current study was to investigate how well the olfactory functional magnetic resonance imaging (fMRI) can effectively distinguish between normosmic...
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The use of immune checkpoint inhibitors (ICIs) in melanoma patients has significantly improved treatment outcomes. Unfortunately, ICI therapy is associated with specific immune-related adverse events (irAEs). There is limited data on the use of ICIs in patients with autoimmune or allergic diseases, because these patients have typically been excluded from clinical trials. Eosinophilic inflammatory bowel disease (primary eosinophilic gastrointestinal disorders) is a rare condition defined as eosinophilic...
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Introduction: Mucoepidermoid carcinoma (MEC) of the upper aerodigestive tract (UADT) is an uncommon malignancy, with limited literature available on its clinical and pathologic characteristics. Here, we describe the behavior of MEC of the UADT including pathologic characteristics and predictors of nodal metastasis. Methods: Retrospective cohort study of patients with MEC of the UADT treated at an academic medical center from January 2008 to May 2018. Data was collected about demographics and tumor...
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Objective: Head trauma can cause deafness in cases with and without a skull base fracture. Anatomic disruption can occur with skull base fractures, but inner ear structures can also be damaged by the concussive forces of the trauma even without fracture. It is thought that negative prognostic indicators for successful cochlear implantation (CI) for hearing rehabilitation include fractures involving the otic capsule or ossification of the cochlea. This review evaluates success of CI in posttrauma...
Objective: A new active transcutaneous bone conduction hearing implant system that uses piezoelectric technology has been developed: an active osseointegrated steady-state implant system (OSI). This was the first clinical investigation undertaken to demonstrate clinical performance, safety, and benefit of the new implant system. Study Design and Setting: A multicenter prospective within-subject clinical investigation was conducted. Patients: Fifty-one adult subjects with mixed...
Objective: The purpose of this study is to determine the feasibility of magnetic resonance imaging (MRI) without general anesthesia (GA) for infants being evaluated for sensorineural hearing loss (SNHL) using the bundle and scan technique. Study Design: Retrospective study. Setting: Pediatric tertiary care hospital. Patients: All infants who underwent MRI using the bundle and scan technique as part of the diagnostic workup for unilateral or bilateral SNHL between June...
Objectives: To investigate the intracochlear position of the latest Cochlear Nucleus 532 electrode array compared with the straight Nucleus 522 and the precurved 512 arrays and determine the effect of the electrode–modiolus distance on electrically evoked compound action potential, C-levels, electrically evoked stapedius reflex thresholds (ESRTs), and impedances. Methods: Postoperative high-resolution cone beam computational tomography images of 30 patients with Cochlear Nucleus 532,...
Objective: To define the relationships among ear preference strength, audiometric interaural asymmetry magnitude, and hearing impairment. Study Design: Prospective, cross-sectional. Setting: Academic audiology clinic. Patients: Adults. Interventions: Diagnostic. Main Outcome Measures: Patient-reported ear preference strength using a seven-category preference (no preference; left or right somewhat, strongly, or completely) scheme, hearing disability...
Objectives: To determine the limits of visualization during transcanal endoscopic ear surgery (EES) by correlating the relationship between radiologic and endoscopic anatomy using angled optics. Methods: Radiology and endoscopic visualization of tensor fold, protympanum, facial sinus (FS), sinus tympani (ST), subtympanic sinus (STS), hypotympanum, and aditus ad antrum were analyzed using a transcanal approach in 30 human temporal bones specimens with different angled endoscopes (0 degree,...
Objective: To determine the effects of cochlear implant (CI) hearing rehabilitation on quality of life in older patients (≥65 yr). Study design: Prospective observational study. Setting: Department of Oto-Rhino-Laryngology, Medical University Frankfurt/Main. Patients: Patients aged between 65 and 86 years who received unilateral CI therapy for the first time. Intervention: Unilateral cochlear implantation. Main Outcome Measures: In addition to audiological...
Hypothesis: A terra cotta plaque [LMU 2551] from the Neo-Babylonian period (c.629-539 BCE), housed in the museum of the Archaeology Center at Loyola Marymount University, Los Angeles, is a representation of right peripheral facial paralysis. Background: Ancient representations of pathology are rare and often difficult to identify. This is particularly true of Assyrian-Babylonian cultures where, despite numerous surviving medical texts, artistic examples of disease are almost non-existent....
Aligning Hearing Aid and Cochlear Implant Improves Hearing Outcome in Bimodal Cochlear Implant Users
Objective: Patients with unilateral deafness and residual hearing on the contralateral ear can benefit from a cochlear implant (CI) on one side and a hearing aid (HA) on the other. However, hearing improvement among these patients is heterogenous. Interindividual differences in bimodal benefit may be caused by a mismatch of CI and HA. The aim of this study was to clinically apply a HA fitting strategy and to evaluate hearing outcome with and without a dedicated bimodal fitting formula. Study...
Objective: To investigate the prevalence and risk of subsequent dementia in subjects with sudden hearing loss during a 7-year follow-up period through comparisons with cohorts matched by sex, age group, and year of index date. Study Design: A retrospective matched-cohort study. Setting: The Longitudinal Health Insurance Database 2000 (LHID2000) in Taiwan. Patients: This study included a total of 11,148 subjects, including 1,858 in the study group and 9,290 in the comparison...
Objective: To identify differences in the vestibulo-ocular reflex (VOR) gain value and the peak saccade velocity in the suppression video head impulse test paradigms according to the age of the subject and the direction of the impulse. Study Design: Retrospective chart analysis. Setting: Tertiary referral hospital. Patients/Interventions: Between October 2017 and May 2019, we enrolled subjects who had previous histories of dizziness but no dizziness over the last 1...
Feasibility and Efficacy of Vibrant Soundbridge Short Process Coupler in Patients With Aural Atresia
Objectives: Different options are available for hearing restoration in patients with aural atresia. Middle ear implantation with the Vibrant Soundbridge (VSB) has been used successfully in many patients with aural atresia with conductive or mixed hearing loss. The aim of the current study was to assess the safety and the efficiency of VSBs coupled to the short process of the incus in patients with aural atresia with conductive or mixed hearing loss. Methods: The study was a retrospective...
Objectives: Intraoperative electrocochleography (ECochG) has provided insight regarding inner ear pathophysiology during neurotologic procedures. In this study, intraoperative ECochG findings are reported in patients who presented with episodic aural and vestibular symptoms during resection of posterior fossa neoplasms. Patients: Three patients with episodic vertigo who underwent resection of posterior fossa tumors. Intervention: Intraoperative ECochG was performed before and...
Objective: Age-related hearing loss (ARHL) is the third most challenging disability in older adults. Noise is a known modifiable risk factor of ARHL, which can drive adverse health effects. Few large-scale studies, however, have shown how chronic noise exposure (CNE) impacts the progression of ARHL and tinnitus. Study Design: Retrospective large-scale study. Setting: Audiology clinical practice. Patients: In this study, 928 individuals aged 30-100 years without (n=497)...
Objective: Hearing loss remains a significant morbidity for patients with vestibular schwannomas (VS). A growing number of reports suggest audibility with cochlear implantation following VS resection; however, there is little consensus on preferred timing and cochlear implant (CI) performance. Data Sources: A systematic literature search of the Ovid Medline, Embase, Scopus, and clinicaltrails.gov databases was performed on 9/7/2018. PRISMA reporting guidelines were followed. Study...
Objective: To evaluate the relationship between degree of cognitive impairment and gray-matter density changes in the auditory cortex. Study Design: Retrospective case-control. Patients: Six hundred sixty-three patients of a tertiary referral center cognitive disorders clinic. Intervention: Magnetic resonance imaging. Main Outcome Measures: Ratios of gray matter density of the primary auditory cortex (A1) to whole brain and auditory association cortex (AAC)...
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Objective: To characterize presurgical symptoms and treatment history and postoperative course in patients with medically recalcitrant Menière's disease undergoing transmastoid labyrinthectomy in the post-intratympanic gentamicin era. Study Design: Retrospective case series. Setting: Tertiary academic medical center. Patients: All patients who underwent transmastoid labyrinthectomy for medically recalcitrant Menière's disease in 2003 to 2019 by the senior author. ...
Objective: Only a handful of case reports exist describing posttraumatic sutural diastasis in the calvarium and none report concurrent temporal bone involvement. We aim to describe diastasis along the temporal bone suture lines in the setting of temporal bone trauma and to identify clinical sequelae. Study Design: Retrospective case review. Setting: Tertiary Level 1 trauma center. Patients: Forty-four patients aged 18 and younger who suffered a temporal bone fracture...
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