Related Articles Phase 3 trial of a small volume subcutaneous 6-month duration leuprolide acetate treatment for central precocious puberty. J Clin Endocrinol Metab. 2020 Aug 01;: Authors: Klein KO, Freire A, Gryngarten MG, Kletter GB, Benson M, Miller BS, Dajani TS, Eugster EA, Mauras N Abstract CONTEXT: Gonadotropin releasing hormone agonists (GnRHa) are standard of care for central precocious puberty (CPP). A 6-month subcutaneous injection...
Related Articles 5-Year Estimated Glomerular Filtration Rate in Patients with Hypoparathyroidism Treated with and Without rhPTH(1-84). J Clin Endocrinol Metab. 2020 Aug 01;: Authors: Chen KS, Gosmanova EO, Curhan GC, Ketteler M, Rubin M, Swallow E, Zhao J, Wang J, Sherry N, Krasner A, Bilezikian JP Abstract CONTEXT: Chronic hypoparathyroidism (HypoPT) is conventionally managed with oral calcium and active vitamin D. Recombinant human parathyroid...
Related Articles Bilateral adrenal hemorrhage in Coronavirus disease 2019 patient: A case report. J Clin Endocrinol Metab. 2020 Aug 01;: Authors: Frankel M, Feldman I, Levine M, Frank Y, Bogot NR, Benjaminov O, Kurd R, Breuer GS, Munter G Abstract CONTEXT: Bilateral adrenal hemorrhage is a rare condition with potentially life-threatening consequences as acute adrenal insufficiency. Early adrenal axis testing, as well as directed imaging, is...
Treatment options for gonadotroph tumors: current state and perspectives. J Clin Endocrinol Metab. 2020 Jul 31;: Authors: Ilie MD, Raverot G Abstract CONTEXT: Gonadotroph tumors represent approximatively one-third of anterior pituitary tumors, but despite their frequency, no medical treatment is currently recommended for them. This would be greatly needed because following surgery, which is the first-line treatment, a significant percentage...
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Related Articles Effects of cTBS on the Frequency-Following Response and Other Auditory Evoked Potentials. Front Hum Neurosci. 2020;14:250 Authors: López-Caballero F, Martin-Trias P, Ribas-Prats T, Gorina-Careta N, Bartrés-Faz D, Escera C Abstract The frequency-following response (FFR) is an auditory evoked potential (AEP) that follows the periodic characteristics of a sound. Despite being a widely studied biosignal in auditory neuroscience,...
Related Articles Citalopram reduces glutamatergic synaptic transmission in the auditory cortex via activation of 5-HT1A receptors. Neuroreport. 2019 12 18;30(18):1316-1322 Authors: Cervantes-Ramírez V, Canto-Bustos M, Aguilar-Magaña D, Pérez-Padilla EA, Góngora-Alfaro JL, Pineda JC, Atzori M, Salgado H Abstract Serotonin modulates cognitive processes and is related to various psychiatric disorders, including major depression. Administration...
Related Articles Projection from the Amygdala to the Thalamic Reticular Nucleus Amplifies Cortical Sound Responses. Cell Rep. 2019 07 16;28(3):605-615.e4 Authors: Aizenberg M, Rolón-Martínez S, Pham T, Rao W, Haas JS, Geffen MN Abstract Many forms of behavior require selective amplification of neuronal representations of relevant environmental signals. Emotional learning enhances sensory responses in the sensory cortex, yet the underlying...
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Related Articles Epidemiological Patterns and Treatment Outcomes in a Private Practice Community Voice Clinic. J Voice. 2020 Jul 28;: Authors: Thijs Z, Knickerbocker K, Watts CR Abstract OBJECTIVES: Voice therapy is administered by speech-language pathologists in multiple practice settings, including private practice community voice clinics. However, the evidence for diagnosis patterns and voice treatment outcomes in community voice clinics...
Related Articles Specifics and diagnostic procedure in reflux-related dysphonia. Wiad Lek. 2020;73(4):814-817 Authors: Sowa K, Łobaczuk-Sitnik A, Piszczatowski B, Duchnowska E, Kosztyła-Hojna B, Nadolny K, Ładny JR, Zdrojkowski M Abstract Voice is a work tool for many professional groups. Currently, cases of dysphonia of multiple origin consist a growing issue. Voice disorders may result from disturbed voice production process, congenital defects,...
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Related Articles Naso-Ethmoidal Phosphaturic Mesenchymal Tumor: A Rare Tumor Site for an Uncommon Paraneoplastic Syndrome. Ear Nose Throat J. 2020 Jul 30;:145561320940869 Authors: Riminucci M, Colangelo L, Ungari C, Cassoni A, Salvatore M, Corsi A PMID: 32729744 [PubMed - as supplied by publisher]
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Preradiation tooth extraction and jaw osteoradionecrosis: Nationwide population-based retrospective study in Taiwan. Clin Otolaryngol. 2020 Aug 01;: Authors: Liao PH, Chu CH, Tang PL, Wu PC, Kuo TJ Abstract OBJECTIVE: Radiotherapy (RT) for head and neck cancer (HNC) within 7 days of tooth extraction is contraindicated because it may increase the risk of osteoradionecrosis of the jaw (ORNJ). However, delayed RT could compromise survival...
Analysis of the effectiveness of coupon-mediated newborn hearing screening program through comparison of two government-funded pilot projects in South Korea. Int J Pediatr Otorhinolaryngol. 2020 Jul 11;136:110256 Authors: Park SK, Chang J, Chung YS, Oh SH Abstract OBJECTIVE: The aims of this study are to compare the results of two government-funded newborn hearing screening (NHS) pilot programs and evaluate the feasibility and the effectiveness...
Comprehensive analysis of significant genes and immune cell infiltration in HPV-related head and neck squamous cell carcinoma. Int Immunopharmacol. 2020 Jul 29;87:106844 Authors: Xu L, Jin Y, Qin X Abstract Head and neck squamous cell carcinoma (HNSCC) is malignancy which impairs the life quality of patients and seriously threatens human life. HPV infection has increasingly been recognized as a significant etiology for HNSCC initiation...
Differential mutation spectrum and immune landscape in African Americans versus whites: A possible determinant to health disparity in head and neck cancer. Cancer Lett. 2020 Jul 29;: Authors: Chaudhary S, Dam V, Ganguly K, Sharma S, Atri P, Chirravuri R, Cox JL, Sayed Z, Jones DT, Ganti AK, Ghersi D, Macha MA, Batra SK Abstract African Americans (AA) with Head and Neck Squamous Cell Carcinoma (HNSCC) have a worse disease prognosis than...
The Effects of Menopause on Neuromuscular Parameters of the Rat Vocal Folds. Laryngoscope. 2020 Aug 01;: Authors: Lenell C, Johnson AM Abstract OBJECTIVES/HYPOTHESIS: Menopause adversely affecs power and endurance of the limb muscles. However, despite clinical observations that menopause corresponds to negative changes of the voice, the direct effects of estrogen deprivation on the thyroarytenoid muscles are unknown. The purpose of this...
Related Articles Olfactory Fluctuation Revisited. Laryngoscope. 2020 Aug 01;: Authors: Hsieh JW, Daskalou D, Detroux V, Sipione R, Senn P, Hugentobler M, Landis BN Abstract OBJECTIVES: Many patients complain about olfactory fluctuation (OF), which is a symptom commonly attributed to sinonasal disease. Data-based evidence for its association with sinonasal disease is scarce. The aim of the study is to identify explanatory variables associated...
Related Articles Long-Term Influence of Electrode Array Length on Speech Recognition in Cochlear Implant Users. Laryngoscope. 2020 Aug 01;: Authors: Canfarotta MW, Dillon MT, Buchman CA, Buss E, O'Connell BP, Rooth MA, King ER, Pillsbury HC, Adunka OF, Brown KD Abstract OBJECTIVES/HYPOTHESIS: Results from a prospective trial demonstrated better speech recognition for cochlear implant (CI) recipients implanted with a long lateral wall electrode...
Related Articles Salvage Surgery in Head and Neck Cancer. Oral Dis. 2020 Aug 01;: Authors: van Weert S, Leemans CR Abstract Salvage surgery after failed organ preservation treatment offers challenges for both the patient and the surgeon. The outcome is often uncertain and even today, five year overall survival does not exceed 50 percent. The chemoradiotherapy induced toxicity asks for meticulous discussion and planning in a multidisciplinary...
Related Articles Effects of Vocal Training on Thyroarytenoid Muscle Neuromuscular Junctions and Myofibers in Young and Older Rats. J Gerontol A Biol Sci Med Sci. 2020 Jul 16;: Authors: Shembel AC, Lenell C, Chen S, Johnson AM Abstract The purpose of this investigation was to determine the effects of vocal training on neuromuscular junction (NMJ) morphology and muscle fiber size and composition in the thyroarytenoid muscle, the primary muscle...
Related Articles Programmed cell death ligand-1 and cytotoxic T cell infiltrates in metastatic cutaneous squamous cell carcinoma of the head and neck. Head Neck. 2020 Aug 01;: Authors: Kraft S, Gadkaree SK, Deschler DG, Lin DT, Hoang MP, Emerick KS Abstract BACKGROUND: Metastatic cutaneous squamous cell carcinoma (cSCC) carries a poor prognosis. Increased numbers of CD8+ cytotoxic T cells are associated with a favorable prognosis and programmed...
Related Articles Primary tumor volume as a predictor of distant metastases and survival in patients with sinonasal mucosal melanoma. Head Neck. 2020 Aug 01;: Authors: Flukes S, Lohia S, Barker CA, Cracchiolo JR, Ganly I, Patel SG, Roman BR, Shah JP, Shoushtari AN, Tabar V, Shah A, Cohen MA Abstract BACKGROUND: Sinonasal mucosal melanoma (SNMM) is an aggressive cancer with high mortality. Identifying patients at risk of distant metastasis...
Related Articles Prediction of distant metastases in patients with squamous cell carcinoma of head and neck using DWI and DCE-MRI. Head Neck. 2020 Aug 01;: Authors: Chawla S, Kim SG, Loevner LA, Wang S, Mohan S, Lin A, Poptani H Abstract BACKGROUND: The primary purpose was to evaluate the prognostic potential of diffusion imaging (DWI) and dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) in predicting distant metastases in...
Related Articles Expanded exposure and detailed anatomic analysis of the superior orbital fissure: Implications for endonasal and transorbital approaches. Head Neck. 2020 Aug 01;: Authors: Li L, London NR, Chen X, Prevedello DM, Carrau RL Abstract This study aimed to ascertain the maximal exposure of the superior orbital fissure (SOF) afforded by combining endonasal and transorbital endoscopic approaches. Six cadaveric specimens (12 sides)...
Related Articles Clinical evaluation of an automated virtual surgical planning platform for mandibular reconstruction. Head Neck. 2020 Aug 01;: Authors: Wang E, Durham JS, Anderson DW, Prisman E Abstract BACKGROUND: Virtual surgical planning (VSP), via commercial services or developed in-house, has been applied to facilitate head and neck reconstruction. We evaluate a custom, automated planning software. METHODS: Prospectively,...
Related Articles Quality of life changes following three-dimensional printing of prosthesis for large nasal septal perforations - our experience of 13 patients. Clin Otolaryngol. 2020 Jul 31;: Authors: Medikeri GS, Khong GC, Fleming S, Malhotra T, Leong SC Abstract Large nasal septal perforations have higher extrusion rates with pre-fabricated septal obturators. A prospective cohort study was conducted including patients with septal perforation...
Related Articles Low-dose aspirin use and risk of head and neck cancer - A Danish nationwide case-control study. Br J Clin Pharmacol. 2020 Jul 31;: Authors: de la Cour CD, Verdoodt F, Aalborg GL, von Buchwald C, Friis S, Dehlendorff C, Kjaer SK Abstract Results concerning a potential preventive effect of aspirin on head and neck cancer (HNC) are conflicting. We examined the association between low-dose aspirin use and HNC risk overall and...
Related Articles Circulating microRNAs modulating glycolysis as non-invasive prognostic biomarkers of HNSCC. Eur Arch Otorhinolaryngol. 2020 Jul 31;: Authors: Avilés-Jurado FX, Muñoz C, Meler C, Flores JC, Gumà J, Benaiges E, Mora J, Camacho M, León X, Vilaseca I, Terra X Abstract BACKGROUND: The identification of prognostic non-invasive biomarkers is a priority for cancer patients' care. Circulating microRNA (miRNAs) have been described...
Related Articles Congenital sensorineural hearing loss as the initial presentation of PTPN11-associated Noonan syndrome with multiple lentigines or Noonan syndrome: clinical features and underlying mechanisms. J Med Genet. 2020 Jul 31;: Authors: Gao X, Huang SS, Qiu SW, Su Y, Wang WQ, Xu HY, Xu JC, Kang DY, Dai P, Yuan YY Abstract BACKGROUND: Germline variants in PTPN11 are the primary cause of Noonan syndrome with multiple lentigines (NSML)...
Related Articles Acute dacryocystitis. Cleve Clin J Med. 2020 Jul 31;87(8):477 Authors: Bakshi SS PMID: 32737045 [PubMed - as supplied by publisher]
Related Articles Society of swallowing and dysphagia of Japan: Position statement on dysphagia management during the COVID-19 outbreak. Auris Nasus Larynx. 2020 Jul 23;: Authors: Kimura Y, Ueha R, Furukawa T, Oshima F, Fujitani J, Nakajima J, Kaneoka A, Aoyama H, Fujimoto Y, Umezaki T Abstract On April 14, the Society of Swallowing and Dysphagia of Japan (SSDJ) proposed its position statement on dysphagia treatment considering the ongoing...
Related Articles BCCIPβ facilitates p53 ubiquitination via binding with E6 protein in high-risk HPV positive head and neck squamous cell carcinoma. Biochem Biophys Res Commun. 2020 Aug 27;529(3):685-691 Authors: Wang F, Wang J, Wang J, Zhang L, Fu H, Li J, Tian T, Zuo J, Lv W, Ma X Abstract BRCA2 And CDKN1A Interacting Protein (BCCIP) is initially identified as a tumor suppressor. Some recent studies confirmed its p53 binding capability....
Related Articles Serum level and clinical significance of vitamin E in children with allergic rhinitis. BMC Pediatr. 2020 Jul 31;20(1):362 Authors: Wang SY, Wang YF, Pan CC, Sun JW Abstract BACKGROUND: Allergic rhinitis (AR) is one of the most prevalent allergic diseases in children. This study aimed to investigate the association between serum concentrations of vitamin E and AR to determine if the vitamin E level is correlated with the...
Related Articles Characteristics of velopharyngeal dysfunction in 22q11.2 deletion syndrome: a retrospective case-control study. J Otolaryngol Head Neck Surg. 2020 Jul 31;49(1):54 Authors: Failla S, You P, Rajakumar C, Dworschak-Stokan A, Doyle PC, Husein M Abstract OBJECTIVE: To identify and describe the dynamic features of velopharyngeal dysfunction (VPD) in patients with 22q11.2 deletion syndrome relative to patients with non-syndromic...
Related Articles Adult laryngeal Embryonal Rhabdomyosarcoma: a case report and literature review. BMC Surg. 2020 Jul 31;20(1):173 Authors: Hu J, Lu D, Ren J, Wen Q, Zhou J, Gan W, Liu J, Liu S, Yang H, Zou J Abstract BACKGROUND: Laryngeal rhabdomyosarcomas (RMSs) mainly occurred in children, while were extremely rare in adults. Consequently, less information was available to guide clinicians to manage adult RMSs in larynx. CASE...
Convolutional neural network based proton stopping-power-ratio estimation with dual-energy CT: a feasibility study. Phys Med Biol. 2020 Jul 31;: Authors: Lee HH, Park YK, Duan X, Jia X, Jiang SB, Yang M Abstract Dual-energy computed tomography (DECT) has shown a great potential for lowering range uncertainties, which is necessary for truly leveraging the Bragg peak in proton therapy. However, analytical stopping-power-ratio (SPR) estimation...
A review of dose calculation approaches with cone beam CT in photon and proton therapy. Phys Med. 2020 Jul 28;76:243-276 Authors: Giacometti V, Hounsell AH, McGarry CK Abstract BACKGROUND AND PURPOSE: The use of cone beam computed tomography (CBCT) for performing dose calculations in radiation therapy has been widely investigated as it could provide a quantitative analysis of the dosimetric impact of changes in patients during the treatment....
The comparison of prognostic value of tumour volumetric regression ratio and RECIST 1.1 criteria after induction chemotherapy in locoregionally advanced nasopharyngeal carcinoma. Oral Oncol. 2020 Jul 28;111:104924 Authors: Zeng YY, Xiang ZZ, He T, Liu F, Shao BF, Yan RN, Ma JC, Wang XR, Liu L Abstract PURPOSE: To compare the prognostic value of the sum volumetric regression ratio (SVRR) of the primary tumour and metastatic lymph nodes with...
Prognostic impact of CD8-positive tumour-infiltrating lymphocytes and PD-L1 expression in salivary gland cancer. Oral Oncol. 2020 Jul 28;111:104931 Authors: Kesar N, Winkelmann R, Oppermann J, Ghanaati S, Martin D, Neumayer T, Balster S, Rödel C, Rödel F, von der Grün J, Balermpas P Abstract OBJECTIVES: Aim of the study was to evaluate the prognostic impact of CD8-positive (CD8+) tumour-infiltrating lymphocytes (TILs) and PD-L1 expression on...
Diagnostic Utility of High-risk HPV mRNA in Situ Hybridization in Squamous Cell Carcinoma of Unknown Primary in the Head and Neck and Implementing ASCO Guideline Recommendations. Cytopathology. 2020 Jul 31;: Authors: Daneshpajouhnejad P, Miller JA, Maleki Z Abstract BACKGROUND: The American Society of Clinical Oncology (ASCO)-endorsed College of American Pathologists (CAP) 1 recommends high-risk Human Papillomavirus (HR-HPV) testing for...
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