Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Gastric adenocarcinoma is a highly aggressive disease with poor overall survival. The aggressive nature of this disease is in part due to the high intra and inter tumoral heterogeneity and also due to the late diagnosis at presentation. Once progression occurs, treatment is more difficult due to the adaptation of tumors, which acquires resistance to commonly used chemotherapeutics. In this report, using publicly...
Mon Aug 17, 2020 14:14
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:The present study aimed to explore the correlation of protein kinase D 1 with prognosis in bortezomib-treated multiple myeloma patients and further investigate the effect of protein kinase D 1 knockdown on drug sensitivity to bortezomib in multiple myeloma cells.Methods:Totally, 104 de novo symptomatic multiple myeloma patients treated with bortezomib-based regimens and 30 healthy controls were recruited....
Mon Aug 17, 2020 13:05
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:The present study aimed to detect A-kinase interacting protein 1 expression and further explore the association of A-kinase interacting protein 1 with clinical features and prognosis in patients with multiple myeloma.Methods:Totally, 152 de novo symptomatic patients with multiple myeloma and 30 healthy donors were enrolled. Bone marrow mononuclear cells derived plasma cells were collected from patients...
Mon Aug 17, 2020 13:05
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Background/Aims:Nasopharyngeal carcinoma is a common head and neck cancer in South China and Southeast Asia. Radiotherapy is the standard treatment for nasopharyngeal carcinoma. Accumulating evidence showed that the expression of miR-34a was abnormal in nasopharyngeal carcinoma. Here, this study investigates the effect of miR-34a on radiosensitivity of nasopharyngeal carcinoma cells and explored the underlying...
Mon Aug 17, 2020 13:04
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Radiotherapy plays an important role in the treatment of non-small cell lung cancer. Accurate segmentation of the gross target volume is very important for successful radiotherapy delivery. Deep learning techniques can obtain fast and accurate segmentation, which is independent of experts’ experience and saves time compared with manual delineation. In this paper, we introduce a modified version of ResNet and apply...
Mon Aug 17, 2020 13:00
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:The purpose of this study was to evaluate the changes in pulmonary function after wedge resection, segmentectomy, and lobectomy.Methods:The patients were divided into 4 groups: lobectomy group, segmentectomy group, wedge resection group, and mediastinal surgery group. The pulmonary function was evaluated at various time points: 3 days before surgery, 1 month, 6 months, 12 months, and then 24 months after...
Mon Aug 17, 2020 13:00
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Breast cancer (Bca) remains the most common form of malignancy affecting females in China, leading to significant reductions in the mental and physical health of those with this condition. While spindle and kinetochore associated complex subunit 3 (SKA3) is known to be linked with cervical cancer progression, whether it is similarly associated with Bca progression remains unknown. Using shRNA, we specifically...
Mon Aug 17, 2020 13:00
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Hepatocellular carcinoma (HCC) remains to a common cause of tumor mortality worldwide and represents the most common type of lethal hepatic malignancy. The incidence of HCC is swiftly increasing in western countries and southeast Asia. Despite poor prognosis, traditional treatments for advanced HCC appear to be minimally effective or even useless since patients are usually diagnosed in the advanced stage of disease....
Mon Aug 17, 2020 13:00
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:This study aimed to investigate the correlation of long noncoding RNA plasmacytoma variant translocation 1 with clinical features and prognosis in patients with multiple myeloma.Methods:The bone marrow samples were collected from 128 patients with de novo symptomatic multiple myeloma (before initial treatment) and 30 healthy donors (on the enrollment). Long noncoding RNA plasmacytoma variant translocation...
Mon Aug 17, 2020 13:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου