Nature Communications, Published online: 18 August 2020; doi:10.1038/s41467-020-17911-0Herpesvirus virions have an outer lipid membrane dotted with glycoproteins that enable fusion with cell membranes to initiate entry and establish infection. Here the authors elucidate the structural mechanism of a neutralizing antibody derived from a patient infected by the herpesvirus varicella-zoster virus and targeted to its fusogen, glycoprotein-B.
Tue Aug 18, 2020 03:00
Nature Communications, Published online: 18 August 2020; doi:10.1038/s41467-020-17988-7Bacteria can form wall-deficient variants, or L-forms, that divide by a simple mechanism that does not require the FtsZ-based cell division machinery. Here, Wu et al. study L-forms in microfluidic systems to show the importance of geometric effects for cell growth, chromosome segregation and cell division.
Tue Aug 18, 2020 03:00
Nature Communications, Published online: 18 August 2020; doi:10.1038/s41467-020-17896-wFLOWERING LOCUS M (FLM) is known as a repressor of Arabidopsis flowering. Here, the authors show that a single intronic substitution of FLM modulates leaf color and plant growth strategy along the leaf economics spectrum, as well as plays a role in plant adaptation.
Tue Aug 18, 2020 03:00
An exponential build-up in seismic energy suggests a months-long nucleation of slow slip in Cascadia
Nature Communications, Published online: 18 August 2020; doi:10.1038/s41467-020-17754-9Using machine learning algorithms, the authors here identify slow slip precursors in the Cascadia subduction zone to last for months - which in turn argues for a much better predictability of slow slip rupture.
Tue Aug 18, 2020 03:00
Nature Communications, Published online: 18 August 2020; doi:10.1038/s41467-020-17936-5Herpes simplex virus establishes lifelong latency in ganglionic neurons, which are the source for recurrent infection. Here Aubert et al. report a promising antiviral therapy based on gene editing with adeno-associated virus-delivered meganucleases, which leads to a significant reduction in ganglionic HSV loads and HSV reactivation.
Tue Aug 18, 2020 03:00
Nature Communications, Published online: 18 August 2020; doi:10.1038/s41467-020-17842-wMiniaturizing efficient triboelectric nanogenerators remains a challenge. Here, the authors propose a MEMS-based micro triboelectric device for acoustic energy transfer and signal communication which is capable of generating the voltage signal of 16.8 mV and 12.7 mV through oil and sound-attenuation medium respectively with 63kPa at 1 MHz ultrasound input.
Tue Aug 18, 2020 03:00
Nature Communications, Published online: 18 August 2020; doi:10.1038/s41467-020-17776-3Here the authors show second harmonic generation (SHG) from a centrosymmetric organic superconductor κ-(BEDT-TTF)2Cu[N(CN)2]Br. They find unusual temperature dependence and CEP-sensitive nature of the SHG which are explained in terms of nonlinear current.
Tue Aug 18, 2020 03:00
Nature Communications, Published online: 18 August 2020; doi:10.1038/s41467-020-17666-8Receptor tyrosine kinase mutations are frequent and associated with poor prognosis in acute myeloid leukemia (AML). Here the authors show that the antipsychotic drug chlorpromazine reduces AML cells viability by perturbing the intracellular localization of FLT3-ITD and KIT-D816V.
Tue Aug 18, 2020 03:00
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