Related Articles Tipifarnib as a Precision Therapy for HRAS-Mutant Head and Neck Squamous Cell Carcinomas. Mol Cancer Ther. 2020 Jul 29;: Authors: Gilardi M, Wang Z, Proietto M, Chillà A, Calleja-Valera JL, Goto Y, Vanoni M, Janes MR, Mikulski Z, Gualberto A, Molinolo AA, Ferrara N, Gutkind JS, Burrows F Abstract Tipifarnib is a potent and highly selective inhibitor of farnesyltransferase (FT). FT catalyzes the post-translational attachment...
Fri Jul 31, 2020 13:12
Related Articles Human Nasal Turbinate Tissues in Organ Culture as a Model for Human Cytomegalovirus Infection at the Mucosal Entry Site. J Virol. 2020 Jul 29;: Authors: Alfi O, From I, Yakirevitch A, Drendel M, Wolf M, Meir K, Zakay-Rones Z, Nevo Y, Elgavish S, Ilan O, Weisblum Y, Tayeb S, Gross M, Jonas W, Ives J, Oberbaum M, Panet A, Wolf DG Abstract The initial events of viral infection at the primary mucosal entry site following horizontal...
Fri Jul 31, 2020 13:12
Detection and Oncologic Outcomes of Head and Neck Squamous Cell Carcinoma of Unknown Primary Origin.
Related Articles Detection and Oncologic Outcomes of Head and Neck Squamous Cell Carcinoma of Unknown Primary Origin. Anticancer Res. 2020 Aug;40(8):4207-4214 Authors: Lee MY, Fowler N, Adelstein D, Koyfman S, Prendes B, Burkey BB Abstract BACKGROUND/AIM: To assess factors that predict detection of tumors and oncologic outcomes in head and neck squamous cell carcinoma of unknown primary (SCCUP). PATIENTS AND METHODS: This was...
Fri Jul 31, 2020 13:12
Related Articles Head and Neck Cancer Survival Disparities by Race and Rural-Urban Context. Cancer Epidemiol Biomarkers Prev. 2020 Jul 29;: Authors: Clarke JA, Despotis AM, Ramirez RJ, Zevallos JP, Mazul AL Abstract BACKGROUND: This study aims to examine the relationship between race and rural-urban context in head and neck cancer (HNC) survival and determine factors that potentially drive this disparity. METHODS: Using the National...
Fri Jul 31, 2020 13:12
Related Articles Transcriptome network of the papillary thyroid carcinoma radiation marker CLIP2. Radiat Oncol. 2020 Jul 29;15(1):182 Authors: Selmansberger M, Michna A, Braselmann H, Höfig I, Schorpp K, Weber P, Anastasov N, Zitzelsberger H, Hess J, Unger K Abstract BACKGROUND: We present a functional gene association network of the CLIP2 gene, generated by de-novo reconstruction from transcriptomic microarray data. CLIP2 was previously...
Fri Jul 31, 2020 13:12
Related Articles Recommendations from the Canadian Association of Head and Neck Surgical Oncology for the Management of Head and Neck Cancers during the COVID-19 pandemic. J Otolaryngol Head Neck Surg. 2020 Jul 29;49(1):53 Authors: O'Connell DA, Seikaly H, Isaac A, Pyne J, Hart RD, Goldstein D, Yoo J, Canadian Association of Head and Neck Surgical Oncology Abstract INTRODUCTION: The SARS-CoV-2 virus (COVID19) pandemic has placed extreme...
Fri Jul 31, 2020 13:12
Related Articles Convolutional neural networks for head and neck tumor segmentation on 7-channel multiparametric MRI: a leave-one-out analysis. Radiat Oncol. 2020 Jul 29;15(1):181 Authors: Bielak L, Wiedenmann N, Berlin A, Nicolay NH, Gunashekar DD, Hägele L, Lottner T, Grosu AL, Bock M Abstract BACKGROUND: Automatic tumor segmentation based on Convolutional Neural Networks (CNNs) has shown to be a valuable tool in treatment planning and...
Fri Jul 31, 2020 13:12
Related Articles SARS-CoV-2 specific serological pattern in healthcare workers of an Italian COVID-19 forefront hospital. BMC Pulm Med. 2020 Jul 29;20(1):203 Authors: Sotgiu G, Barassi A, Miozzo M, Saderi L, Piana A, Orfeo N, Colosio C, Felisati G, Davì M, Gerli AG, Centanni S Abstract BACKGROUND: COVID-19 is an infectious disease caused by a novel coronavirus (SARS-CoV-2). The immunopathogenesis of the infection is currently unknown. Healthcare...
Fri Jul 31, 2020 13:12
Related Articles Comparative effectiveness trial of transoral head and neck surgery followed by adjuvant radio(chemo)therapy versus primary radiochemotherapy for oropharyngeal cancer (TopROC). BMC Cancer. 2020 Jul 29;20(1):701 Authors: Bußmann L, Laban S, Wittekindt C, Stromberger C, Tribius S, Möckelmann N, Böttcher A, Betz CS, Klussmann JP, Budach V, Muenscher A, Busch CJ Abstract BACKGROUND: For loco-regionally advanced, but transorally...
Fri Jul 31, 2020 13:12
Related Articles The value of CT, MRI, and PET-CT in detecting retropharyngeal lymph node metastasis of head and neck squamous cell carcinoma. BMC Med Imaging. 2020 Jul 29;20(1):88 Authors: Kim JH, Choi KY, Lee SH, Lee DJ, Park BJ, Yoon DY, Rho YS Abstract BACKGROUND: The diagnostic accuracies of the imaging studies should be clearly acknowledged in managing head and neck cancer patients; however, the accuracies of preoperative imaging...
Fri Jul 31, 2020 13:12
Related Articles Implementing the Biodesign Process for Medical Device Innovation in Head and Neck Surgery. Surg Innov. 2020 Jul 30;:1553350620943796 Authors: Dharmawan R, Ho H, Ng HHM, Iyer NG, Tan HK, Tan NC Abstract Introduction. The Stanford Biodesign process is a needs-driven approach to innovation which begins in the clinical setting and environment and is championed by practicing clinicians and surgeons. Here, our team applied the...
Fri Jul 31, 2020 13:12
Related Articles [Chinese expert consensus on multiple primary cancers of hypopharynx and esophagus]. Zhonghua Wai Ke Za Zhi. 2020 Aug 01;58(8):589-595 Authors: Committee of Esophageal Cancer in China Anti-Cancer Association, Chinese Working Group on Cooperative Diagnosis and Treatment of Hypopharyngeal and Esophageal Cancer Abstract Hypopharyngeal cancer and esophageal cancer often occur synchronously or metachronously. Timely screening,...
Fri Jul 31, 2020 13:12
Related Articles Intrinsic Radiosensitivity Is Not the Determining Factor in Treatment Response Differences between HPV Negative and HPV Positive Head and Neck Cancers. Cells. 2020 Jul 27;9(8): Authors: Reid P, Staudacher AH, Marcu LG, Olver I, Moghaddasi L, Brown MP, Li Y, Bezak E Abstract Head and neck squamous cell carcinomas (HNSCC) resulting from human papillomavirus (HPV) are increasing in incidence but demonstrate significantly better...
Fri Jul 31, 2020 13:12
Related Articles NIR Photodynamic Destruction of PDAC and HNSCC Nodules Using Triple-Receptor-Targeted Photoimmuno-Nanoconjugates: Targeting Heterogeneity in Cancer. J Clin Med. 2020 Jul 27;9(8): Authors: Bano S, Obaid G, Swain JWR, Yamada M, Pogue BW, Wang K, Hasan T Abstract Receptor heterogeneity in cancer is a major limitation of molecular targeting for cancer therapeutics. Single-receptor-targeted treatment exerts selection pressures...
Fri Jul 31, 2020 13:12
Related Articles [Superficial temporal artery composite perforator flap in repair of temporal skin and soft tissue defects and reconstruction of sideburns]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2020 Apr 15;34(4):493-496 Authors: Liu M, Nie K, Hu P, Wei Z, Wang D, Zeng X Abstract Objective: To investigate the feasibility and effectiveness of repairing temporal skin and soft tissue defects and reconstructing sideburns with superficial...
Fri Jul 31, 2020 13:12
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