Cyanidin-3-O-β-glucoside inactivates NLRP3 inflammasome and alleviates alcoholic steatohepatitis via SirT1/NF-κB signaling pathway. Free Radic Biol Med. 2020 Aug 14;: Authors: Zhou Y, Wang S, Wan T, Huang Y, Pang N, Jiang X, Gu Y, Luo J, Yang L Abstract Alcoholic liver disease (ALD) is a major cause of liver disease worldwide. In patients with ALD, an increased level of hepatic inflammasome components was observed, together with an increased...
Related Articles Activated protein phosphatase 2A disrupts nutrient sensing balance between mTORC1 and AMPK causing sarcopenia in alcoholic liver disease. Hepatology. 2020 Aug 16;: Authors: Davuluri G, Welch N, Sekar J, Gangadhariah M, Alsabbagh Alchirazi K, Mohan ML, Kumar A, Kant S, Thapaliya S, Stine M, McMullen MR, McCullough RL, Stark GR, Nagy LE, Naga Prasad SV, Dasarathy S Abstract BACKGROUND AND AIMS: Despite the high clinical significance...
Related Articles Appetite is correlated with octopamine and hemolymph sugar levels in forager honeybees. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2019 08;205(4):609-617 Authors: Mayack C, Phalen N, Carmichael K, White HK, Hirche F, Wang Y, Stangl GI, Amdam GV Abstract Insects have rapidly changing energy demands, so they primarily rely on hemolymph and other carbohydrates to carry out life activities. However, how gustatory responsiveness...
Related Articles Pharmacological Stimulation of Mitochondrial Biogenesis Using the Food and Drug Administration-Approved β2-Adrenoreceptor Agonist Formoterol for the Treatment of Spinal Cord Injury. J Neurotrauma. 2019 03 19;36(6):962-972 Authors: Scholpa NE, Williams H, Wang W, Corum D, Narang A, Tomlinson S, Sullivan PG, Rabchevsky AG, Schnellmann RG Abstract A hallmark of the progressive cascade of damage referred to as secondary spinal...
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Abstract Evolving debate suggests that handgrip strength, a measure of muscular strength, might be associated with the risk of fractures; however, the evidence is conflicting. We aimed to assess the association of handgrip strength with the risk of fracture in the general population. Handgrip strength, measured using a dynamometer, was assessed at baseline in a population-based sample of 853 men and women aged 61–73 years in the Kuopio Ischemic Heart Disease prospective cohort....
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51 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/08/18PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
51 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/08/18PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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242 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/08/18PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
242 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/08/18PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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5010 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/08/18PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Many hospitals like this one in Alberta, Canada, have set up screening checkpoints for COVID-19. Other facilities can do the same. (Graham Ruttan/Unsplash/)Zoë McLaren is an associate professor of public policy at the University of Maryland, Baltimore County. This story originally featured on The Conversation.Broad access to testing is one of the most powerful tools to keep the COVID-19 pandemic under control until there’s an effective vaccine in use. Diagnostic testing, which is used in medical...
We're all surrounded by personal clouds of dust and debris smaller than the eye can see. (Pexels/)Scientists have debated the role of droplets both large and small in the transmission of SARS-CoV-2 since the beginning of the COVID-19 pandemic. But findings published this week in the journal Nature Communications suggest that researchers who study airborne viruses like SARS-CoV-2 and influenza need to look more closely at the role of another tiny vector: microscopic dust. “Our data very clearly shows...
Pictures of phone screens are boring. Here's the back of the phone. (Stan Horaczek /)You’re easily forgiven if you don’t know how much RAM your smartphone has inside. No one will judge you if you’re not exactly sure which specific version of Qualcomm’s Snapdragon processor lives inside your device. In short, diving into a phone’s spec sheet means different things to various segments of the smartphone-using public. For some, it’s something to pore over and argue about on the internet. For others,...
Goat frogs, which are native to Brazil’s Atlantic rainforest, are the first known case of an amphibian species in which males maintain lasting relationships with more than one female mate. (Credit: Fábio de Sá/)For male members of the tropical frog species Thoropa taophora, also known as goat frogs, the breeding season is filled with responsibilities. During this ten-month long period, males must do typical frog duties like stake out and defend their territories but they must also navigate an unusually...
A bigger, easier, lovelier breakfast. (Amazon/)You can do a lot with a stovetop and a couple nice pans, but there are some dishes that just land better when they’re cooked on a griddle. Flat-top cooking appliances are a favorite in restaurant kitchens thanks to their large surface area, even heat distribution, and easy-to-clean design, but most home cooks simply don’t have the space or budget for such an installation. Enter the double-burner griddle: when placed directly on the stovetop, these unique...
A proper survival kit includes essentials like a compass, matches, knife, and food. (Tim MacWelch/)This story was originally featured on Outdoor Life.Ask 100 outdoor enthusiasts to write up a shopping list for a wilderness survival kit and you’ll get 100 different lists. The same is true for preppers building disaster preparedness kits or picking which everyday carry gear to bring with them. We all like different products and worry about different scenarios (and there are specialized survival kits...
Add some variety to your morning routine. (Karl Fredrickson via Unsplash/)Every coffee lover knows you have to mix up your routine every now and again. It’s important to try new roasts, beans, and drink types so you can be a cultured coffee connoisseur. A great way to do just that is with a subscription box that will deliver coffee to your door on a schedule. It’ll feel like coffee Christmas every few weeks when you open your box and see all the fun things to try. Each package offers something different,...
For the right cut. (Amazon/)The santoku knife may look a lot like a chef’s knife—but it’s got a few key differences that make it an incredibly useful tool, and an essential in every kitchen. Originally from Japan, the santoku—which translates to “three uses” or “three virtues”—is around 5 to 8 inches (versus the chef’s knife which can be up to 10 inches), has a slightly more square build which gives it a weightier feel, and a less pointy tip.We’ve chosen some of our favorites.Agile and very, very...
An F5 tornado in Oklahoma City, May 3, 1999 (NOAA/)A fire tornado might sound like an unfortunate coincidence involving a weather front and a wildfire, but the truth is actually even wilder. Firenadoes, to use the vernacular, occur when a fire burns so intensely that it creates its own weather.The heat inside a large fire causes air to rise, forming eddies that can spiral into a vortex called a fire whirl. A fire tornado is essentially a much larger whirl. Those rising eddies become strong updrafts,...
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Objective Biomarkers for Total Added Sugar Intake - Are We on a Wild Goose Chase? Adv Nutr. 2020 Aug 17;: Authors: Louie JCY Abstract Misreporting of added sugar intake has been the major criticism of studies linking high added sugar consumption to adverse health outcomes. Despite the advancement in dietary assessment methodologies, the bias introduced by self-reporting can never be completely eliminated. The search for an objective biomarker...
Effects of Dietary Glycemic Index and Glycemic Load on Cardiometabolic and Reproductive Profiles in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Adv Nutr. 2020 Aug 17;: Authors: Kazemi M, Hadi A, Pierson RA, Lujan ME, Zello GA, Chilibeck PD Abstract Women with polycystic ovary syndrome (PCOS) exhibit cardiometabolic (e.g., insulin resistance) and associated reproductive disruptions....
The Effect of Aerobic and Resistance Training and Combined Exercise Modalities on Subcutaneous Abdominal Fat: A Systematic Review and Meta-analysis of Randomized Clinical Trials. Adv Nutr. 2020 Aug 17;: Authors: Yarizadeh H, Eftekhar R, Anjom-Shoae J, Speakman JR, Djafarian K Abstract Subcutaneous abdominal adipose tissue (SAT), is the largest fat depot and major provider of free fatty acids to the liver. Abdominal fat is indirectly (via increased...
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Related Articles A randomised controlled pilot trial of the influence of non-native English accents on examiners' scores in OSCEs. BMC Med Educ. 2020 Aug 15;20(1):268 Authors: Kozato A, Patel N, Shikino K Abstract BACKGROUND: Objective structured clinical examinations (OSCEs) are important aspects of assessment in medical education. There is anecdotal evidence suggesting that students with non-native English accents (NNEA) may be subjected to...
Related Articles Outcomes of trauma education workshop in Vietnam: improving diagnostic and surgical skills. BMC Med Educ. 2020 Aug 15;20(1):267 Authors: Choi S, Kim J, Heo J, Nguyen DTN, Nguyen SH, Kim WH Abstract BACKGROUND: Unintentional injuries have emerged as a significant public health issue in low- and middle-income countries (LMIC), especially in Vietnam, where there is a poor quality of care for trauma. A scarcity of formal and informal...
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Related Articles The effect of a community-based e-health program to promote the role of physical activity among healthy adults in Hungary. BMC Public Health. 2020 Aug 17;20(Suppl 1):1059 Authors: Makai A, Füge K, Breitenbach Z, Betlehem J, Ács P, Lampek K, Figler M Abstract BACKGROUND: Physically active lifestyle can prolong the years spent without chronic diseases and is strongly associated with good mental and physical health. The goal of...
Related Articles Cross-cultural adaptation and validation of the Global Physical Activity Questionnaire among healthy Hungarian adults. BMC Public Health. 2020 Aug 17;20(Suppl 1):1056 Authors: Ács P, Betlehem J, Oláh A, Bergier B, Morvay-Sey K, Makai A, Prémusz V Abstract BACKGROUND: Physical activity (PA) is an important factor among the determinants of health due to it's protective factor and preventive role. Self-reported measures such as...
Related Articles Association with subjective measured physical activity (GPAQ) and quality of life (WHOQoL-BREF) of ageing adults in Hungary, a cross-sectional study. BMC Public Health. 2020 Aug 17;20(Suppl 1):1061 Authors: Rétsági E, Prémusz V, Makai A, Melczer C, Betlehem J, Lampek K, Ács P, Hock M Abstract BACKGROUND: It is well known that physical activity (PA) has health benefits. This study aimed to examine physical activity carried out...
Related Articles Protocol for Minute Calisthenics: a randomized controlled study of a daily, habit-based, bodyweight resistance training program. BMC Public Health. 2020 Aug 15;20(1):1242 Authors: Hollingsworth JC, Young KC, Abdullah SF, Wadsworth DD, Abukhader A, Elfenbein B, Holley Z Abstract BACKGROUND: Resistance-training (RT) provides significant health benefits. However, roughly 3/4 of adults in the United States do not meet current Physical...
Related Articles Measurement of public health benefits of physical activity: validity and reliability study of the international physical activity questionnaire in Hungary. BMC Public Health. 2020 Aug 17;20(Suppl 1):1198 Authors: Ács P, Betlehem J, Oláh A, Bergier J, Melczer C, Prémusz V, Makai A Abstract BACKGROUND: To ensure accurate measurement of the health benefits of habitual physical activity in large sample epidemiological studies, physical...
Related Articles Comparative analysis of the economic burdens of physical inactivity in Hungary between 2005 and 2017. BMC Public Health. 2020 Aug 17;20(Suppl 1):1174 Authors: Ács P, Kovács A, Paár D, Hoffbauer M, Szabó P, Szabó T, Stocker M Abstract BACKGROUND: National economies are increasingly facing the challenge of having to finance the prevention and treatment of human diseases, and of having to compensate for the resulting loss of economic...
Related Articles Socioeconomic and geographic variations in antenatal care coverage in Angola: further analysis of the 2015 demographic and health survey. BMC Public Health. 2020 Aug 15;20(1):1243 Authors: Shibre G, Zegeye B, Idriss-Wheeler D, Ahinkorah BO, Oladimeji O, Yaya S Abstract BACKGROUND: In African countries, including Angola, antenatal care (ANC) coverage is suboptimal and maternal mortality is still high due to pregnancy and childbirth-related...
Related Articles Health literacy among participants from neighbourhoods with different socio-economic statuses in the southern region of Hungary: a pilot study. BMC Public Health. 2020 Aug 17;20(Suppl 1):1060 Authors: Bánfai-Csonka H, Bánfai B, Jeges S, Gyebnár B, Betlehem J Abstract BACKGROUND: Health literacy (HL) has a deep impact on people's decisions about their health and health care system. Measurement and improvement of HL level is essential...
Related Articles Association of nutrition, water, sanitation and hygiene practices with children's nutritional status, intestinal parasitic infections and diarrhoea in rural Nepal: a cross-sectional study. BMC Public Health. 2020 Aug 15;20(1):1241 Authors: Shrestha A, Six J, Dahal D, Marks S, Meierhofer R Abstract BACKGROUND: Providing universal access to safe water, sanitation and hygiene (WASH) in remote Nepal remains challenging. We investigated...
Related Articles Associations between fitness levels and self-perceived health-related quality of life in community - dwelling for a group of older females. BMC Public Health. 2020 Aug 17;20(Suppl 1):1057 Authors: Ihász F, Schulteisz N, Finn KJ, Szabó K, Gangl J, Nagy D, Ács P, Oláh A Abstract BACKGROUND: For older adults perceived quality of life has been linked to the ability to accomplish everyday tasks, a functional capacity which is thought...
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23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "BMJ Open"[jour] These pubmed results were generated on 2020/08/18PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "BMJ Open"[jour] These pubmed results were generated on 2020/08/18PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Related Articles Diet and nutritional status during early adult life have immediate and persistent effects on queen bumble bees. Conserv Physiol. 2019;7(1):coz048 Authors: Woodard SH, Duennes MA, Watrous KM, Jha S Abstract Many insects sequester nutrients during developmentally programmed periods, which they metabolize during subsequent life history stages. During these periods, failure to store adequate nutrients can have persistent effects...
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Related Articles The Diet Quality of a Sample of Predominantly Racial Minority Children From Low-Income Households Is Lower During the Summer vs School Year: Results From the Project Summer Weight and Environmental Assessment Trial Substudy. J Acad Nutr Diet. 2020 Aug 13;: Authors: Hopkins LC, Tiba S, Westrick M, Gunther C Abstract BACKGROUND: Little is known about the diet quality of racial minority children during the summertime when school...
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Related Articles Long noncoding RNA NEAT1 promotes progression of glioma as a ceRNA by sponging miR-185-5p to stimulate DNMT1/mTOR signaling. J Cell Physiol. 2020 Aug 16;: Authors: Yu H, Xu A, Wu B, Wang M, Chen Z Abstract Long noncoding RNA nuclear paraspeckle assembly transcript 1 (NEAT1) is regarded as an oncogene in multiple cancers. Previous studies have shown that NEAT1 is involved in the proliferation and tumorigenesis of glioma cells,...
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Arsenic (III) and/or copper (II) induces oxidative stress in chicken brain and subsequent effects on mitochondrial homeostasis and autophagy. J Inorg Biochem. 2020 Aug 01;211:111201 Authors: Liu Y, Zhao H, Wang Y, Guo M, Mu M, Xing M Abstract As two quite complicated substances, arsenic (As) and copper (Cu) have polluted to the environment. As is highly toxic and could cause nerve damage. Cu is involved in the occurrence of oxidative stress....
Evaluation of cobalt(III) complexes as potential hypoxia-responsive carriers of esculetin. J Inorg Biochem. 2020 Aug 08;211:111211 Authors: Palmeira-Mello MV, Caballero AB, Ribeiro JM, de Souza-Fagundes EM, Gamez P, Lanznaster M Abstract Differentiation between hypoxic and normoxic tissues have been exploited for the development of selective chemotherapeutic agents. In this context, cobalt(III)-based coordination compounds have been designed...
Related Articles Synthesis of Pt(II) complexes of the type [Pt(1,10-phenanthroline)(SArFn)2] (SArFn = SC6H3-3,4-F2; SC6F4-4-H; SC6F5). Preliminary evaluation of their in vitro anticancer activity. J Inorg Biochem. 2020 Jul 25;211:111206 Authors: Backman-Blanco G, Valdés H, Ramírez-Apan MT, Cano-Sanchez P, Hernandez-Ortega S, Orjuela AL, Alí-Torres J, Flores-Gaspar A, Reyes-Martínez R, Morales-Morales D Abstract A series of Pt(II) complexes of...
Related Articles Reaction mechanism of lysyl oxidase-like 2 (LOXL2) studied by computational methods. J Inorg Biochem. 2020 Jul 27;211:111204 Authors: Dong G, Lin LR, Xu LY, Li EM Abstract Lysyl oxidase-like 2 (LOXL2) is a copper-dependent amine oxidase that catalyzes the oxidative deamination of the ε-amino group of lysines/hydroxylysines on substrate proteins (collagen and elastin) to form aldehyde groups. The generated aldehyde groups are...
Related Articles Synthesis, structure, and biological activity of bis(benzimidazole)amino thio- and selenoether nickel complexes. J Inorg Biochem. 2020 Jul 28;211:111198 Authors: Muñoz-Patiño N, Sánchez-Eguía BN, Araiza-Olivera D, Flores-Alamo M, Hernández-Ortega S, Martínez-Otero D, Castillo I Abstract Four new nickel (II) complexes with bis(benzimidazole)thio- and selenoether-based ligands have been synthesized and characterized in the solid...
Related Articles Synthesis, characterization and in vitro biological evaluation of novel organotin(IV) compounds with derivatives of 2-(5-arylidene-2,4-dioxothiazolidin-3-yl)propanoic acid. J Inorg Biochem. 2020 Jul 26;211:111207 Authors: Pantelić NĐ, Zmejkovski BB, Božić B, Dojčinović B, Banjac NR, Wessjohann LA, Kaluđerović GN Abstract Two novel triphenyltin(IV) compounds, [Ph3SnL1] (L1 = 2-(5-(4-fluorobenzylidene)-2,4-dioxotetrahydrothiazole-3-yl)propanoate...
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The Positive Association of Plasma Myristic Acid and Apolipoprotein CIII Concentrations. J Nutr. 2020 Aug 17;: Authors: Fernandez ML PMID: 32805056 [PubMed - as supplied by publisher]
Processing Apples to Puree or Juice Speeds Gastric Emptying and Reduces Postprandial Intestinal Volumes and Satiety in Healthy Adults. J Nutr. 2020 Aug 17;: Authors: Krishnasamy S, Lomer MCE, Marciani L, Hoad CL, Pritchard SE, Paul J, Gowland PA, Spiller RC Abstract BACKGROUND: Whole apples produce greater satiety than processed apples, but the underlying mechanisms remain unclear. OBJECTIVE: Our aim was to assess the intragastric...
Nonvitamin, Nonmineral Dietary Supplement Use in Individuals with Rheumatoid Arthritis. J Nutr. 2020 Aug 17;: Authors: Skiba MB, Hopkins LL, Hopkins AL, Billheimer D, Funk JL Abstract BACKGROUND: Over-the-counter, natural product-based (nonvitamin, nonmineral) dietary supplement (NVNM DS) use is common in adults with rheumatoid arthritis (RA), a group at risk for drug-DS interactions, due to polypharmacy, but this use is underreported to health...
Dietary Variation among Children Meeting and Not Meeting Minimum Dietary Diversity: An Empirical Investigation of Food Group Consumption Patterns among 73,036 Children in India. J Nutr. 2020 Aug 17;: Authors: Beckerman-Hsu JP, Kim R, Sharma S, Subramanian SV Abstract BACKGROUND: Minimum Dietary Diversity (MDD) is a widely used indicator of adequate dietary micronutrient density for children 6-23 mo old. MDD food-group data remain underutilized,...
Riboflavin Is an Important Determinant of Vitamin B-6 Status in Healthy Adults. J Nutr. 2020 Aug 17;: Authors: Jungert A, McNulty H, Hoey L, Ward M, Strain JJ, Hughes CF, McAnena L, Neuhäuser-Berthold M, Pentieva K Abstract BACKGROUND: Riboflavin is required to generate the active form of vitamin B-6 (pyridoxal 5'-phosphate; PLP) in tissues, but the relevance of this metabolic interaction for nutritional status of vitamin B-6 is unclear because...
Avocado Consumption Alters Gastrointestinal Bacteria Abundance and Microbial Metabolite Concentrations among Adults with Overweight or Obesity: A Randomized Controlled Trial. J Nutr. 2020 Aug 17;: Authors: Thompson SV, Bailey MA, Taylor AM, Kaczmarek JL, Mysonhimer AR, Edwards CG, Reeser GE, Burd NA, Khan NA, Holscher HD Abstract BACKGROUND: Avocados are rich in dietary fiber and monounsaturated fatty acids (MUFAs), nutrients that have been...
Habitual Coffee and Tea Consumption and Cardiometabolic Biomarkers in the UK Biobank: The Role of Beverage Types and Genetic Variation. J Nutr. 2020 Aug 17;: Authors: Cornelis MC, van Dam RM Abstract BACKGROUND: Mechanisms linking habitual consumption of coffee and tea to the development of type 2 diabetes and cardiovascular diseases remain unclear. OBJECTIVES: We leveraged dietary, genetic, and biomarker data collected from the UK...
Addition of Whole Wheat Flour During Injera Fermentation Degrades Phytic Acid and Triples Iron Absorption from Fortified Tef in Young Women. J Nutr. 2020 Aug 17;: Authors: Herter-Aeberli I, Fischer MM, Egli IM, Zeder C, Zimmermann MB, Hurrell RF Abstract BACKGROUND: Iron deficiency is a major public health concern in Ethiopia, where the traditional diet is based on tef injera. Iron absorption from injera is low due to its high phytic acid (PA)...
Proton-NMR Metabolomics of Rainbow Trout Fed a Plant-Based Diet Supplemented with Graded Levels of a Protein-Rich Yeast Fraction Reveal Several Metabolic Processes Involved in Growth. J Nutr. 2020 Aug 17;: Authors: Roques S, Deborde C, Richard N, Marchand Y, Larroquet L, Prigent S, Skiba-Cassy S, Moing A, Fauconneau B Abstract BACKGROUND: Plant raw materials are commonly used in aquafeeds, as marine resources are unsustainable. However, full...
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Related Articles Preconditioning human pharyngeal motor cortex enhances directional metaplasticity induced by repetitive transcranial magnetic stimulation. J Physiol. 2020 Aug 17;: Authors: Cheng I, Scarlett H, Zhang M, Hamdy S Abstract KEY POINTS: Recent studies have proposed therapeutic potential for repetitive transcranial magnetic stimulation (rTMS) in swallowing rehabilitation, yet its outcomes vary across individuals and studies. Such...
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Related Articles A robust and interpretable end-to-end deep learning model for cytometry data. Proc Natl Acad Sci U S A. 2020 Aug 14;: Authors: Hu Z, Tang A, Singh J, Bhattacharya S, Butte AJ Abstract Cytometry technologies are essential tools for immunology research, providing high-throughput measurements of the immune cells at the single-cell level. Existing approaches in interpreting and using cytometry measurements include manual or automated...
Related Articles Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression. Proc Natl Acad Sci U S A. 2020 Aug 14;: Authors: Fishbein A, Wang W, Yang H, Yang J, Hallisey VM, Deng J, Verheul SML, Hwang SH, Gartung A, Wang Y, Bielenberg DR, Huang S, Kieran MW, Hammock BD, Panigrahy D Abstract Toxic environmental carcinogens promote cancer via genotoxic and nongenotoxic pathways, but...
Related Articles Coupled transmembrane mechanisms control MCU-mediated mitochondrial Ca2+ uptake. Proc Natl Acad Sci U S A. 2020 Aug 14;: Authors: Vais H, Payne R, Paudel U, Li C, Foskett JK Abstract Ca2+ uptake by mitochondria regulates bioenergetics, apoptosis, and Ca2+ signaling. The primary pathway for mitochondrial Ca2+ uptake is the mitochondrial calcium uniporter (MCU), a Ca2+-selective ion channel in the inner mitochondrial membrane....
Related Articles Universal free-energy landscape produces efficient and reversible electron bifurcation. Proc Natl Acad Sci U S A. 2020 Aug 14;: Authors: Yuly JL, Zhang P, Lubner CE, Peters JW, Beratan DN Abstract For decades, it was unknown how electron-bifurcating systems in nature prevented energy-wasting short-circuiting reactions that have large driving forces, so synthetic electron-bifurcating molecular machines could not be designed and...
Related Articles An endosymbiont's journey through metamorphosis of its insect host. Proc Natl Acad Sci U S A. 2020 Aug 14;: Authors: Kaltenpoth M PMID: 32801211 [PubMed - as supplied by publisher]
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Μία νέα μελέτη από τα Πανεπιστήμια της Αριζόνα, της Οκλαχόμα και το Κολέγιο Hamilton βρήκε ότι το συναίσθημα της ζήλειας μπορεί να αποτελέσει χρήσιμο εργαλείο για τη διατήρηση των φιλικών σχέσεων. Όπως αναφέρεται στη σχετική δημοσίευση στο Journal of Personality and Social Psychology, η ζήλεια σχετίστηκε με την αξία της φιλίας και κινητοποίησε συμπεριφορές που διατήρησαν τη σχέση. «Οι φίλοι είναι μια σημαντική πτυχή της ζωής, ειδικά τώρα που η πανδημία του κορωνοϊού δυσκολεύει την καθημερινότητά...
Η ωκυτοκίνη, γνωστή και ως «ορμόνη της αγάπης» μπορεί να αποτελεί ισχυρό σύμμαχο στον έλεγχο και την πρόληψη της οστεοπόρωσης, σύμφωνα με μία μελέτη επιστημόνων από το Πανεπιστήμιο του Σάο Πάολο (UNESP) στη Βραζιλία. Η μελέτη, που δημοσιεύθηκε στο Scientific Reports, έδειξε ότι όταν η ορμόνη χορηγήθηκε σε θηλυκά ποντίκια που βρίσκονταν στο τέλος της γόνιμης περιόδου τους, μπόρεσε να αναστρέψει την πρόδρομη κατάσταση της οστεοπόρωσης, δηλαδή τη μειωμένη οστική πυκνότητα και δύναμη των οστών και την...
Οι ατομικές δραστηριότητες των παιδιών στο εξωτερικό περιβάλλον ίσως κρατούν τον πρωταρχικό ρόλο στο να συνδεθούν και να αγαπήσουν τη φύση αντλώντας παράλληλα όλα τα οφέλη για την ψυχική και σωματική τους υγεία, βάσει των ευρημάτων μελέτης του Πανεπιστημίου της Βόρειας Καρολίνας. Οι ομαδικές δραστηριότητες είναι φυσικά εξαιρετικά σημαντικές και απαραίτητες για το χτίσιμο του δεσμού με τη φύση, την υγεία, χαρά και κοινωνικοποίηση των παιδιών, πάντως σύμφωνα με τη νέα έρευνα το σημείο εκκίνησης για...
Η ερευνητική μελέτη, που διεξήχθη υπό την αιγίδα του Πανεπιστημίου Ιατρικών Επιστημών και Επιστημών Υγείας RCSI της Ιρλανδίας, συσχετίζει την ατμοσφαιρική ρύπανση κατά τη διάρκεια του χειμώνα με αυξημένες νοσηλείες για αγγειακό εγκεφαλικό επεισόδιο στη χώρα. Πρόκειται για την πρώτη μελέτη που καταγράφει βραχυπρόθεσμη συσχέτιση μεταξύ ατμοσφαιρικής ρύπανσης και εγκεφαλικού επεισοδίου στην Ιρλανδία -μία χώρα, μάλιστα, η οποία δεν διαθέτει υψηλά επίπεδα ατμοσφαιρικής ρύπανσης. Τα σχετικά συμπεράσματα...
Μια παράπλευρη και απροσδόκητη επίπτωση του τσιγάρου στην υγεία των καπνιστριών ανέδειξε πρόσφατη έρευνα. Το εύρημα αποδεικνύεται ιδιαιτέρως σημαντικό, δεδομένου πως ο καρκίνος του πνεύμονα ευθύνεται για τους περισσότερους θανάτους γυναικών ανάμεσα στους άλλους τύπους καρκίνου. Η μελέτη που δημοσιεύτηκε στο BMJ Open έδειξε πως οι ενεργές καπνίστριες αμελούν τον τυπικό έλεγχο για καρκίνο και όταν εν τέλει διαγιγνώσκονται, ο καρκίνος βρίσκεται σε προχωρημένο στάδιο. Σύμφωνα με την επιστημονική ομάδα,...
Ο τακτικός έλεγχος μεγάλου αριθμού ατόμων θα παίξει τεράστιο ρόλο στην παρακολούθηση της μετάδοσης του SARS-CoV-2. Η γρήγορη ανίχνευση και απομόνωση των ενεργών περιπτώσεων – δηλαδή ατόμων που μπορούν να μεταδώσουν τον ιό, είτε είναι συμπτωματικά είτε ασυμπτωματικά – είναι βασικό εργαλείο για τον περιορισμό της εξάπλωσης της νόσου. Επιπλέον, απαιτούνται ακριβή δεδομένα σχετικά με τον αριθμό των ενεργών περιπτώσεων για την χάραξη της υγειονομικής πολιτικής και των ανάλογων μέτρων (σε τοπικό, και...
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