SARS-CoV-2, the coronavirus that causes Covid-19, enters human cells by binding of its viral spike protein to the membrane-bound form of the aminopeptidase angiotensin-converting enzyme 2 (ACE2). From the viewpoint of human physiology, ACE2 plays an important regulatory role in the…
Fri May 01, 2020 03:00
Presentation of Case. Dr. John H. Stone: A 37-year-old man was evaluated in the rheumatology clinic of this hospital for joint pain and rash. The patient had been well until 2 years before this evaluation, when intermittent arthralgias developed in the joints of the hands. Four months before…
Thu Apr 30, 2020 03:00
Persons with mental disorders are at increased risk for other types of mental disorders and for a range of general medical conditions. These medical conditions contribute to a decreased quality of life, increased health care utilization, and premature death in many persons with mental disorders.…
Thu Apr 30, 2020 03:00
How long will this pandemic last? When will we find a treatment or vaccine? Which drug should we give our patients? Will we run out of personal protective equipment (PPE)? When will everyone return to work? We find ourselves in a time of great economic, social, and medical uncertainty. Faced with a…
Tue Apr 28, 2020 03:00
Related ArticlesUncovering Factors Influencing Instructors' Decision Process when Considering Implementation of a Course-Based Research Experience. CBE Life Sci Educ. 2020 Jun;19(2):ar13 Authors: Genné-Bacon EA, Wilks J, Bascom-Slack C Abstract Course-based undergraduate research experiences (CUREs) are an effective way to expose large numbers of students to authentic research, yet most laboratory courses still use traditional "cookbook" methods. While...
Sat May 02, 2020 16:51
Related ArticlesRecent Research on Students' Identities: Advancing Theory and Practice to Disrupt Inequities. CBE Life Sci Educ. 2020 Jun;19(2):fe3 Authors: Gouvea J Abstract Students' identities shape and are shaped by learning experiences inside and outside classrooms. Three recent papers present theoretical frameworks for understanding the complex dynamics of identity development with implications for equity in science and mathematics education.PMID:...
Sat May 02, 2020 16:51
Related ArticlesDeveloping the DELTA: Capturing Cultural Changes in Undergraduate Departments. CBE Life Sci Educ. 2020 Jun;19(2):ar15 Authors: Ngai C, Pilgrim ME, Reinholz DL, Corbo JC, Quan GM Abstract Departments are now recognized as an important locus for sustainable change on university campuses. Making sustainable changes typically requires a shift in culture, but culture is complex and difficult to measure. For this reason, cultural changes are...
Sat May 02, 2020 16:51
Related ArticlesSignaling Inclusivity in Undergraduate Biology Courses through Deliberate Framing of Genetics Topics Relevant to Gender Identity, Disability, and Race. CBE Life Sci Educ. 2020 Jun;19(2):es2 Authors: Hales KG Abstract The study of genetics centers on how encoded information in DNA underlies similarities and differences between individuals and how traits are inherited. Genetics topics covered in a wide variety of undergraduate biology classrooms...
Sat May 02, 2020 16:51
Related ArticlesDiving into the Details: Constructing a Framework of Random Call Components. CBE Life Sci Educ. 2020 Jun;19(2):ar14 Authors: Waugh AH, Andrews TC Abstract Random call is a randomized approach to select a student or group of students to share their thinking with the whole class. There are potential costs and benefits of random call in undergraduate courses, yet we lack insight about how this strategy is actually implemented and why instructors...
Sat May 02, 2020 16:51
Related ArticlesResources for Teaching and Assessing the Vision and Change Biology Core Concepts. CBE Life Sci Educ. 2020 Jun;19(2):es1 Authors: Branchaw JL, Pape-Lindstrom PA, Tanner KD, Bissonnette SA, Cary TL, Couch BA, Crowe AJ, Knight JK, Semsar K, Smith JI, Smith MK, Summers MM, Wienhold CJ, Wright CD, Brownell SE Abstract The Vision and Change report called for the biology community to mobilize around teaching the core concepts of biology. This...
Sat May 02, 2020 16:51
Related ArticlesPositive Impact of Multiple-Choice Question Authoring and Regular Quiz Participation on Student Learning. CBE Life Sci Educ. 2020 Jun;19(2):ar16 Authors: Riggs CD, Kang S, Rennie O Abstract We previously developed an online multiple-choice question authoring, learning, and self-assessment tool that we termed Quizzical. Here we report statistical analyses over two consecutive years of Quizzical use in a large sophomore-level introductory...
Sat May 02, 2020 16:51
Related ArticlesUndergraduate Biology Education Research Gordon Research Conference: A Meeting Report. CBE Life Sci Educ. 2020 Jun;19(2):mr1 Authors: Dolan EL, Borrero M, Callis-Duehl K, Musgrove MMC, de Lima J, Ero-Tolliver I, Gerhart LM, Goodwin EC, Hamilton LR, Henry MA, Herrera J, Huot B, Kiser S, Ko ME, Kravec ME, Lee M, Limeri LB, Peffer ME, Pires D, Lugo JSR, Sharp SM, Suarez NA Abstract The 2019 Undergraduate Biology Education Research Gordon...
Sat May 02, 2020 16:51
Studies in animals have shown that angiotensin-converting enzyme 2 (ACE2), a membrane-bound aminopeptidase that is abundantly expressed in the lungs, the heart, and other tissues, is used by coronaviruses as a functional receptor for their entrance into the cells. Angiotensin-receptor blockers…
Fri May 01, 2020 03:00
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), can infect host cells by means of interaction with membrane-bound angiotensin-converting enzyme 2 (ACE2) on respiratory epithelium. ACE2 is part of the…
Fri May 01, 2020 03:00
Caustic substances injure tissue by means of a chemical reaction on direct physical contact. Often thought of as acids or bases, caustics broadly include desiccants, vesicants, and protoplasmic poisons. The term "corrosive" is often used interchangeably with "caustic," but corrosion implies a…
Thu Apr 30, 2020 03:00
To the Editor: Brodifacoum, a long-acting vitamin K epoxide cycle antagonist, is a rodenticide encountered in intentional ingestions and as a contaminant of some synthetic cannabinoid products. Serious brodifacoum poisoning is characterized by life-threatening hemorrhage. Brodifacoum poisoning is…
Thu Apr 30, 2020 03:00
To the Editor: Despite the risk of rapid respiratory failure and cardiac complications due to Covid-19, it is unclear whether there is an association between Covid-19 and out-of-hospital cardiac arrest. The Lombardy region of Italy was among the first areas to have an outbreak of Covid-19 outside…
Wed Apr 29, 2020 03:00
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