Related ArticlesSummary from the First Kidney Cancer Research Summit, September 12-13, 2019: A Focus on Translational Research. J Natl Cancer Inst. 2020 May 02;: Authors: Choueiri TK, Atkins MB, Bakouny Z, Carlo MI, Drake CG, Jonasch E, Kapur P, Lewis B, Linehan WM, Mitchell MJ, Pal SK, Pels K, Poteat S, Rathmell WK, Rini BI, Signoretti S, Tannir N, Uzzo R, Wood CG, Hammers HJ Abstract Kidney cancer is one of the ten most common cancers both in the United...
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Related ArticlesNeurological manifestations of neurofibromatosis: a review. Neurol Sci. 2020 May 01;: Authors: Bayat M, Bayat A Abstract Neurofibromatosis type 1(NF1) is a dominantly inherited genetic disorder caused by a mutation in the NF1 tumor-suppressor gene. Patients are prone to develop benign and malignant tumors not only in the central and peripheral nervous system but also in other parts of the body. Apart from tumors, neurofibromatosis may...
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Related ArticlesHow to divide the pancreatic parenchyma in patients with a portal annular pancreas: laparoscopic spleen-preserving distal pancreatectomy for serous cystic neoplasms. Surg Case Rep. 2020 May 01;6(1):89 Authors: Kuriyama N, Hatanaka T, Gyoten K, Hayasaki A, Fujii T, Iizawa Y, Kato H, Murata Y, Tanemura A, Kishiwada M, Sakurai H, Mizuno S Abstract BACKGROUND: Portal annular pancreas (PAP) is a rare pancreatic anomaly in which the uncinate...
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Related ArticlesHydrocele in recurrent acute pancreatitis caused by testicular venous obstruction: A case report of a rare complication (CARE-compliant). Medicine (Baltimore). 2020 May;99(18):e19738 Authors: Chang YH, Weng SY, Shiue SJ, Cheng CL, Wu MS Abstract RATIONALE: Scrotal swelling is a rare complication of acute pancreatitis. It had been explained by fluid accumulation in scrotum originated from abdomen. Here we demonstrated a case of recurrent...
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Related ArticlesPrevalence of Cigarette Smoking among Patients with Different Histological Types of Kidney Cancer. Cancer Epidemiol Biomarkers Prev. 2020 May 01;: Authors: Gansler T, Fedewa SA, Flanders WD, Pollack LA, Siegel DA, Jemal A Abstract BACKGROUND: Cigarette smoking is causally linked to renal cell carcinoma (RCC). However, associations for individual RCC histologies are not well-described. Newly-available data on tobacco use from population-based...
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Related ArticlesSmooth muscle tumor of uncertain malignant potential (STUMP): a clinicopathologic analysis of 26 cases. Int J Clin Exp Pathol. 2020;13(4):818-826 Authors: Zheng YY, Liu XB, Mao YY, Lin MH Abstract BACKGROUND: To investigate the clinicopathologic features, differential diagnosis, and factors associated with recurrence in patients with smooth muscle tumors of uncertain malignant potential (STUMP). METHODS: The clinical and pathologic...
Sat May 02, 2020 13:21
Related ArticlesGastric duplication cyst lined by pseudostratified columnar ciliated epithelium masquerading as a pancreatic mucinous cystic neoplasm: a case report and literature review. Int J Clin Exp Pathol. 2020;13(4):785-791 Authors: Zhan C, Zhou B Abstract Gastric duplication cyst (GDC) with a pseudostratified columnar ciliated epithelial (PCCE) is a congenital rare cystic neoplasm, which is often difficult to distinguish from other entities by...
Sat May 02, 2020 13:21
Related ArticlesClear cell sarcoma of the kidney in children: a clinopathologic analysis of three cases. Int J Clin Exp Pathol. 2020;13(4):771-777 Authors: Chen S, Li M, Li R, Cao J, Wu Q, Zhou T, Cai Z, Li N Abstract BACKGROUND: Clear cell sarcoma of the kidney (CCSK) is a rare malignant tumor in children with uncertain histologic and immunohistologic traits. It mostly reveals atypical clinical symptoms similar to other familiar pediatric renal neoplasms,...
Sat May 02, 2020 13:21
Related ArticlesUnusual Presentation of Cutaneous Spindle Cell Squamous Cell Carcinoma: A Case Report. Case Rep Dermatol. 2020 Jan-Apr;12(1):70-75 Authors: Wernheden E, Trøstrup H, Pedersen Pilt A Abstract Cutaneous spindle cell squamous cell carcinoma (SpSCC) is a rare and often aggressive subtype of squamous cell carcinoma (SCC), which usually appears in sun-exposed areas, in areas that have received prior ionizing radiation, or in immunosuppressed...
Sat May 02, 2020 13:21
Related ArticlesQuadruple synchronous primary cancers in a single patient. BMJ Case Rep. 2020 Apr 29;13(4): Authors: Albertsdottir E, Juel J Abstract Patients diagnosed with quadruple synchronous primary cancers are extremely rare and we present here, to the best of our knowledge, the first case report of this combination of primary cancers. A 70-year-old woman was diagnosed with cervical adenocarcinoma, melanoma on the right leg, invasive ductal cell...
Sat May 02, 2020 13:21
Related ArticlesMolecular pathways and targeted therapy in cholangiocarcinoma. Clin Adv Hematol Oncol. 2019 Nov;17(11):630-637 Authors: Dabney RS, Khalife M, Shahid K, Phan AT Abstract Cholangiocarcinoma (CCA) encompasses a rare group of malignancies arising from epithelial cells lining the biliary tree that connects the liver and gallbladder to the small intestine. Most patients present with advanced incurable disease that has a poor prognosis, and...
Sat May 02, 2020 13:21
Related ArticlesRare Hereditary Burden associated with a Hypercalcemic Small-Cell Carcinoma of Cervix in a Young Female Patient. Klin Onkol. 2019;32(6):456-462 Authors: Hruška L, Sirák I, Laco J, Fridrichová P, Nosková H, Slabý O, Pál K, Bočkayová V, Hodek M, Petera J Abstract BACKGROUND: Oncological diseases have, in most cases, a multifactorial etiology, composed of a combination of external and internal environmental factors. Hereditary tumorous...
Sat May 02, 2020 13:21
Related ArticlesCase report: optimal tumor cytoreduction and octreotide with durable disease control in a patient with MEN-1 and Zollinger-Ellison syndrome-over a decade of follow-up. World J Surg Oncol. 2019 Dec 09;17(1):213 Authors: Daniels LM, Khalili M, Morano WF, Simoncini M, Mapow BC, Leaf A, Bowne WB Abstract BACKGROUND: Zollinger-Ellison syndrome (ZES) is a rare condition characterized by hypersecretion of gastrin by gastrinoma tumors leading...
Sat May 02, 2020 13:21
Related ArticlesEndometrioid adenocarcinoma of the rectovaginal septum with invasion of the rectum: a case report and review of literature. World J Surg Oncol. 2019 Dec 04;17(1):206 Authors: Yang H, Gu JJ, Qi Y, Zhao W, Wang XL Abstract BACKGROUND: Malignant transformation of endometriosis in the rectovaginal septum is rare and usually misdiagnosed as a colorectal or gynecological tumor. We report a rare case of primary endometrioid adenocarcinoma...
Sat May 02, 2020 13:21
Related ArticlesCT and MRI manifestations of mediastinal cavernous hemangioma and a review of the literature. World J Surg Oncol. 2019 Dec 04;17(1):205 Authors: Bai Y, Zhao G, Tan Y Abstract BACKGROUND: The cavernous hemangioma of mediastinum (CHM) is a rare benign lesion caused by congenital vascular dysplasia. However, its incidence is extremely low, and patients often lack relevant clinical symptoms. So we analyzed retrospectively some cases to...
Sat May 02, 2020 13:21
Related ArticlesPhotodynamic therapy for basal cell carcinoma of external auditory canal: A case report. Photodiagnosis Photodyn Ther. 2019 Dec;28:102-104 Authors: Xu S, Zhang L, Zhang M Abstract BACKGROUND: Basal cell carcinoma (BCC) that occurs in the external auditory canal (EAC) is rare. Currently reported cases are mainly treated with surgical resection. Here, we described an early-detected BCC of the EAC, which achieved good results with photodynamic...
Sat May 02, 2020 13:21
Related ArticlesOncogenic effects of germline variants in lysosomal storage disease genes. Genet Med. 2019 12;21(12):2695-2705 Authors: Shin J, Kim D, Kim HL, Choi M, Koh Y, Yoon SS Abstract PURPOSE: Clinical and experimental evidence has suggested pathobiological crosstalk between lysosomal storage diseases (LSDs) and cancer. We aimed to elucidate the association between germline variants in LSD genes and cancer. METHODS: We performed aggregate...
Sat May 02, 2020 13:21
Related ArticlesFatal myocarditis and rhabdomyositis in a patient with stage IV melanoma treated with combined ipilimumab and nivolumab. Curr Oncol. 2019 06;26(3):e418-e421 Authors: Saibil SD, Bonilla L, Majeed H, Sotov V, Hogg D, Chappell MA, Cybulsky M, Butler MO Abstract Combination immune checkpoint blockade with concurrent administration of the anti-ctla4 antibody ipilimumab and the anti-PD-1 antibody nivolumab has demonstrated impressive responses...
Sat May 02, 2020 13:21
Related ArticlesOutcome and prognostic features in paediatric pineoblastomas: analysis of cases from the Surveillance, Epidemiology, and End Results registry (1990-2007). Acta Neurochir (Wien). 2019 09;161(9):1799-1807 Authors: Selvanathan SK, Richards O, Alli S, Elliott M, Tyagi AK, Chumas PD Abstract BACKGROUND: Paediatric pineoblastomas are rare central nervous system tumours. Patient and treatment factors associated with outcome are poorly defined...
Sat May 02, 2020 13:21
Related ArticlesDual TGFβ/BMP Pathway Inhibition Enables Expansion and Characterization of Multiple Epithelial Cell Types of the Normal and Cancerous Breast. Mol Cancer Res. 2019 07;17(7):1556-1570 Authors: Prasad M, Kumar B, Bhat-Nakshatri P, Anjanappa M, Sandusky G, Miller KD, Storniolo AM, Nakshatri H Abstract Functional modeling of normal breast epithelial hierarchy and stromal-epithelial cell interactions have been difficult due to inability to...
Sat May 02, 2020 13:21
Related ArticlesPhysical and Family History Variables Associated With Neurological and Cognitive Development in Sturge-Weber Syndrome. Pediatr Neurol. 2019 07;96:30-36 Authors: Day AM, McCulloch CE, Hammill AM, Juhász C, Lo WD, Pinto AL, Miles DK, Fisher BJ, Ball KL, Wilfong AA, Levin AV, Thau AJ, Comi AM, National Institute of Health Sponsor: Rare Disease Clinical Research Consortium (RDCRN) Brain and Vascular Malformation Consortium (BVMC) SWS Investigator Group, Koenig...
Sat May 02, 2020 13:21
Related ArticlesAltering Fundamental Trends in the Emission of Xanthene Dyes. J Org Chem. 2019 03 01;84(5):2585-2595 Authors: Wang LG, Munhenzva I, Sibrian-Vazquez M, Escobedo JO, Kitts CH, Fronczek FR, Strongin RM Abstract Fluorescent small molecules enable researchers and clinicians to visualize biological events in living cells, tissues, and organs in real time. Herein, the focus is on the structure and properties of the relatively rare benzo[ a]xanthenes...
Sat May 02, 2020 13:21
Related Articles[Acute lymphoblastic leukemia - diagnosis and therapy]. Ther Umsch. 2019;76(9):510-515 Authors: Medinger M, Heim D, Lengerke C, Halter JP, Passweg JR Abstract Acute lymphoblastic leukemia - diagnosis and therapy Abstract. Acute lymphoblastic leukemia (ALL) is a rare malignant hematological disease. The incidence of the disease peaks in the childhood and thus is rare in adults, making assessment and care at qualified centers highly desirable....
Sat May 02, 2020 13:21
Related Articles[Tubulocystic renal cell carcinoma. A rare entity in neoplastic renal pathology]. Rev Esp Patol. 2019 Jan - Mar;52(1):57-61 Authors: Martínez I Cózar V, Bauza ME, Blanco Máñez R, Vera-Sempere FJ, Ramos-Soler D Abstract Tubulocystic renal carcinoma is an uncommon neoplasm. We present a case of a patient presenting with multiple renal colic. A nodular cystic lesion was an incidental sonographic finding which increased in size during subsequent...
Sat May 02, 2020 13:21
Related ArticlesDistinct genomic profile and specific targeted drug responses in adult cerebellar glioblastoma. Neuro Oncol. 2019 01 01;21(1):47-58 Authors: Cho HJ, Zhao J, Jung SW, Ladewig E, Kong DS, Suh YL, Lee Y, Kim D, Ahn SH, Bordyuh M, Kang HJ, Sa JK, Seo YJ, Kim ST, Lim DH, Dho YS, Lee JI, Seol HJ, Choi JW, Park WY, Park CK, Rabadan R, Nam DH Abstract Background: Despite extensive efforts on the genomic characterization of gliomas, very few...
Sat May 02, 2020 13:21
The DNA mismatch repair system in sebaceous tumors: an update on the genetics and workup of Muir-Torre syndrome. Cutis. 2019 Mar;105(3):E34-E37 Authors: Dany M Abstract Mutations in the genes encoding the DNA mismatch repair (MMR) are identified in most sebaceous neoplasms. Sebaceous tumors are rare in the general population; however, they are common in patients with inherited or acquired mutations in the MMR system. This article describes the DNA MMR...
Fri May 01, 2020 13:19
Canine tonsillar neoplasia and tonsillar metastasis from various primary neoplasms. Vet Comp Oncol. 2020 Apr 30;: Authors: Mickelson MA, Regan D, Randall EK, Worley D, Seguin B Abstract Tonsillar metastasis from distant primary tumors has not been described in dogs, and reports are rare in humans. The aims of this study were to determine whether tumor metastasis occurs to the canine palatine tonsils and evaluate whether afferent lymphatics drain to the...
Fri May 01, 2020 13:19
Pharmacogenomics Biomarkers of Soft Tissue Sarcoma Therapies. Front Oncol. 2020;10:509 Authors: Caruso C, Garofalo C Abstract Soft tissue sarcomas (STS) are heterogeneous rare malignancies comprising ~1% of all solid cancers in adults and including more than 70 histological and molecular subtypes with different pathological and clinical development characteristics. Over the last two decades, the increased knowledge of the new molecular and genomic mechanisms...
Fri May 01, 2020 13:19
A Case of Short Stature and Severe Osteoporosis in a Young Man with Oculocutaneous Albinism: Syndrome or Coincidence? Cureus. 2020 Apr 24;12(4):e7817 Authors: Oyibo SO Abstract Oculocutaneous albinism (OCA) is a rare autosomal recessive congenital condition characterized by reduced or absent production of the pigment melanin by melanocytes. The affected individuals have increased susceptibility to sunburn and skin cancers. Osteoporosis is a disease entity...
Fri May 01, 2020 13:19
Mucosa-associated Lymphoid Tissue Lymphoma of Colon: A Case Report and Literature Review of Rare Entity. Cureus. 2020 Mar 27;12(3):e7438 Authors: Nagra N, Singhvi AR, Singhvi G Abstract Mucosa-associated lymphoid tissue lymphoma (MALT lymphoma) accounts for approximately 5% of non-Hodgkin lymphomas, and the gastrointestinal (GI) tract is the most common site of involvement. The stomach and small intestine are the most common sites of involvement in the...
Fri May 01, 2020 13:19
Erdheim-Chester Disease and Small Lymphocytic Lymphoma Collision Tumour Presenting as a Perirenal Mass. Case Rep Pathol. 2020;2020:3081824 Authors: Maietta A, Razmpoosh M Abstract Background: Erdheim-Chester disease is a rare histiocytic neoplasm associated with MAPK pathway mutations. Disease manifestation is variable often involving many different organs, mainly bone, retroperitoneum, the heart, and the central nervous system. Histological findings...
Fri May 01, 2020 13:19
Long noncoding RNA BSN-AS2 induced by E2F1 promotes spinal osteosarcoma progression by targeting miR-654-3p/SYTL2 axis. Cancer Cell Int. 2020;20:133 Authors: Zhou X, Li J, Teng J, Liu Y, Zhang D, Liu L, Zhang W Abstract Spinal osteosarcoma (OS) is a rare and aggressive malignancy. Long noncoding RNA (lncRNA) BSN-AS2 has been shown to be an oncogenic gene in several cancers. However, the role and function of BSN-AS2 in spinal OS were unfamiliar. Our study...
Fri May 01, 2020 13:19
Related ArticlesNon-invasive imaging of Young's modulus and Poisson's ratio in cancers in vivo. Sci Rep. 2020 Apr 29;10(1):7266 Authors: Islam MT, Tang S, Liverani C, Saha S, Tasciotti E, Righetti R Abstract Alterations of Young's modulus (YM) and Poisson's ratio (PR) in biological tissues are often early indicators of the onset of pathological conditions. Knowledge of these parameters has been proven to be of great clinical significance for the diagnosis,...
Fri May 01, 2020 13:19
Related ArticlesThe current reality of soft tissue sarcomas: advances, controversies, areas for improvement, and promising new treatments. Expert Rev Anticancer Ther. 2020 Apr 29;:1-11 Authors: Blay JY, Le Cesne A, Demetri GD Abstract Introduction: Soft tissue sarcomas (STS) encompass a group of rare and heterogeneous cancers. Rapid evolution in the field justifies a focused critical review of the clinical literature.Areas covered: Important advances,...
Fri May 01, 2020 13:19
Related ArticlesClinical and Pathological Data of 17 Non-Epithelial Pancreatic Tumors in Cats. Vet Sci. 2020 Apr 27;7(2): Authors: Törner K, Staudacher M, Steiger K, Aupperle-Lellbach H Abstract Tumors of mesenchymal origin are rarely reported in the pancreas. Therefore, this study characterized 17 feline non-epithelial pancreatic tumors, including clinical data, histopathology, and immunohistochemistry. Seventeen feline pancreatic tissue samples were...
Fri May 01, 2020 13:19
Related ArticlesPrimary intracranial fibrosarcoma in a southern sea otter Enhydra lutris nereis. Dis Aquat Organ. 2020 Mar 26;138:207-213 Authors: Armwood AR, Anderson CE, Clauss T, Camus AC Abstract Southern sea otters Enhydra lutris nereis, a threatened marine mammal species, face numerous environmental and infectious disease challenges in their native habitat of coastal California, USA. However, there are few published cases describing neoplasia...
Fri May 01, 2020 13:19
Related ArticlesMapping the Human Exposome to Uncover the Causes of Breast Cancer. Int J Environ Res Public Health. 2019 12 27;17(1): Authors: Bessonneau V, Rudel RA Abstract Breast cancer is an important cause of morbidity and mortality for women, yet a significant proportion of variation in individual risk is unexplained. It is reasonable to infer that unexplained breast cancer risks are caused by a myriad of exposures and their interactions with...
Fri May 01, 2020 13:19
Related ArticlesClinicopathologic characteristics and survival outcomes in neuroendocrine carcinoma of the ovary. Int J Gynecol Cancer. 2020 02;30(2):207-212 Authors: Zhu Y, Meng F, Fang H, Zhang Z, Wang L, Zheng W Abstract OBJECTIVE: Neuroendocrine tumors are rare in the ovary. Definitive epidemiologic and prognostic information for neuroendocrine carcinoma of the ovary is lacking. This retrospective population-based study aimed to elucidate the demographic...
Fri May 01, 2020 13:19
Related ArticlesCushing disease in children and adolescents - assessment of the clinical course, diagnostic process, and effects of the treatment - experience from a single paediatric centre. Pediatr Endocrinol Diabetes Metab. 2019;25(3):127-143 Authors: Wędrychowicz A, Hull B, Tyrawa K, Kalicka-Kasperczyk A, Zieliński G, Starzyk J Abstract INTRODUCTION: Adrenocorticotropic hormone-dependent Cushing syndrome, known as Cushing disease (CD), is a rare...
Fri May 01, 2020 13:19
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