Anxiety is a normal reaction to the stresses we all experience in life. What? Yes, it’s normal to feel that racing heartbeat, catch in your breath, and overall oddness that can feel like panic. Short responses to external circumstances can help you make the right decision. It is when anxious feelings and obsessive thoughts control emotions and interfere with your life that anxiety becomes a problem. Sometimes, after you learn how to handle your anxiety, it may disappear, but in certain cases, there...
Mon Mar 02, 2020 20:30
by Kevin D. Raehtz, Fredrik Barrenäs, Cuiling Xu, Kathleen Busman-Sahay, Audrey Valentine, Lynn Law, Dongzhu Ma, Benjamin B. Policicchio, Viskam Wijewardana, Egidio Brocca-Cofano, Anita Trichel, Michael Gale Jr., Brandon F. Keele, Jacob D. Estes, Cristian Apetrei, Ivona Pandrea Unlike HIV infection, SIV infection is generally nonpathogenic in natural hosts, such as African green monkeys (AGMs), despite life-long high viral replication. Lack of disease progression was reportedly based on the...
Mon Mar 02, 2020 20:55
by Ziah Dean, Jeff Maltas, Kevin Wood Antibiotic combinations are increasingly used to combat bacterial infections. Multidrug therapies are a particularly important treatment option for E. faecalis, an opportunistic pathogen that contributes to high-inoculum infections such as infective endocarditis. While numerous synergistic drug combinations for E. faecalis have been identified, much less is known about how different combinations impact the rate of resistance evolution. In this work, we use...
Mon Mar 02, 2020 20:55
by Pavithra Aravamudhan, Krishnan Raghunathan, Jennifer Konopka-Anstadt, Amrita Pathak, Danica M. Sutherland, Bruce D. Carter, Terence S. Dermody Several barriers protect the central nervous system (CNS) from pathogen invasion. Yet viral infections of the CNS are common and often debilitating. Understanding how neurotropic viruses co-opt host machinery to overcome challenges to neuronal entry and transmission is important to combat these infections. Neurotropic reovirus disseminates through...
Fri Feb 28, 2020 20:43
by Renée M. Van der Sluis, Jennifer M. Zerbato, Jake W. Rhodes, Rachel D. Pascoe, Ajantha Solomon, Nitasha A. Kumar, Ashanti I. Dantanarayana, Surekha Tennakoon, Jérémy Dufloo, James McMahon, Judy J. Chang, Vanessa A. Evans, Paul J. Hertzog, Martin R. Jakobsen, Andrew N. Harman, Sharon R. Lewin, Paul U. Cameron HIV latency is the major barrier to a cure for people living with HIV (PLWH) on antiretroviral therapy (ART) because the virus persists in long-lived non-proliferating and proliferating...
Fri Feb 28, 2020 20:43
Posted by request from the BioBE Center at the University of Oregon: The work of our BioBE team will be represented at five different conferences from May to August 2020. Our projects on hospital-associated infection will be presented at American Society for Microbiology Conference in Chicago, Microbiology in the Built Environment in Andover, NH, ...
Mon Mar 02, 2020 20:21
Abstract Mead is an ancient alcoholic beverage produced through the fermentation of a diluted solution of honey. Due to the peculiar and varied composition of honey, mead production faces several problems, such as slow or stuck fermentations mainly due to the low nitrogen concentration, lack of uniformity of the final product and the production of unpleasant aromas. In this context, this work aimed to select low nitrogen-demand yeast strains and evaluate their potential for the...
Mon Mar 02, 2020 02:00
Abstract Wheat is consumed worldwide because of its high nutritional content and convenience to form different products. Whole wheat is an important source of dietary fiber and its consumption is known to lower the risk of colon cancer, diabetes mellitus and cardiovascular disease. Germination of wheat results in better availability of nutrients and offers many health benefits. In this study, germinated wheat flour (GWF) was prepared and analyzed for its proximate composition,...
Mon Mar 02, 2020 02:00
Abstract Triple ground whole-wheat flour with 18.45% damaged starch was partially substituted by double sifted full-fat stabilised rice bran (SRB) and undamaged-stabilised-debitterised-wheat germ (USDWG) flour to produce high TDF (total dietary fibre), high protein flour for chapati. Five formulations, F1-5 with up to 15% SRB and 20% USDWG incorporations on weight basis were used for baking chapatis. The most sensorially and functionally acceptable formulation (F4), had 10% SRB...
Mon Mar 02, 2020 02:00
Abstract The impact of fermentation and bud size on the antioxidant activity, total phenolic content (TPC), and bioactive compounds of caper buds were investigated. The results showed significant differences in the bioactive properties depending on bud sizes and fermentation process. Antioxidant activity values of fresh caper buds were ranged between 69.61% (bid size) and 72.78% (small size), whereas the values of fermented ones varied between 12.50% (big size) and 39.09% (small...
Mon Mar 02, 2020 02:00
Hajj pilgrimage faces numerous challenges including a high prevalence of respiratory tract infection as well as its prevention strategies. The aim of this study was to develop and validate a questionnaire to e...
Mon Mar 02, 2020 02:00
Despite the misconceptions regarding E-cigarettes (ECs), only a few studies have been conducted in the Middle East that focused on this topic. This study assesses the knowledge of and attitudes towards ECs in ...
Fri Feb 28, 2020 02:00
When returning to work after being on long-term sick leave, individuals may experience varying levels of motivation and self-efficacy. Motivational interviewing (MI) is a counseling style that aims to increase...
Fri Feb 28, 2020 02:00
Neurosity, a neurotech company based in New York, has developed the Notion brain computing platform. The system has a huge range of potential medical applications, including monitoring a patient’s mental health, to diagnosing concussions, to allowing paralyzed patients to control electric wheelchairs. The headset can do this because it incorporates sensors that detect brain activity and translates those signals into specific commands. Notion is the first “brain reading computer,” according...
Mon Mar 02, 2020 20:38
Companion Medical announced that it received FDA clearance for its InPen bolus calculator for fixed dosing and meal estimation. Only 42% of people living with Type 1 diabetes count carbohydrates to determine their mealtime insulin dose, according to the company. Incorrect carb counting and insulin dosages often result in hypo- and hyperglycemia. The bolus calculator is designed to remove the guesswork from insulin dosing for those with either Type 1 or Type 2 insulin-dependent diabetes,...
Mon Mar 02, 2020 16:15
Meniscus tears are a fairly common knee injury. Treatment typically involves complete or partial removal of the damaged meniscus. Without shock-absorbing role of the meniscus, however, patients are at risk for accelerated wear of the knee joint and osteoarthritis. Currently, patients have to wait for many years until they are eligible for a total knee replacement (TKR). Orthopedic surgeons lack options during this period, what they call the “treatment gap.” ATRO Medical is working on another...
Fri Feb 28, 2020 23:58
Emagine Solutions Technology, a startup based in Tucson, Arizona, won FDA clearance for its VistaScan mobile ultrasound system. The product includes ultrasound probes that can interface with a clinician’s own smartphone or tablet, and the company’s app is used to display and manipulate live images produced by the probes. The company developed special software that allows clinicians to use the display of a smartphone or tablet to measure relevant anatomical markers with a to-the-pixel accuracy....
Fri Feb 28, 2020 22:30
3D printing of artificial scaffolds intended to replace injured tissues has become a ballyhooed technology that’s yet to prove itself in clinical practice. One issue that complicates things is that the scaffolds have to match the volume that they’ll be replacing, in both shape and the direction in which cells will have to grow. To do this, 3D models have to be created of the area to be treated and they have to intimately match each patient’s anatomy. Bypassing all this, researchers at the...
Fri Feb 28, 2020 17:07
ConclusionCervical shedding of EBV appears to predict a greater risk of cervical dysplasia in HIV-infected women with a high-risk HPV infection. (Source: Cancer Causes and Control)
Fri Feb 28, 2020 00:00
Background The role of the glycocalyx as the endothelial sensor of an increase in blood flow was assessed in the iliac artery in vivo. Methods Acetylcholine-induced flow mediated dilation was evaluated before and after vascular glycocalyx disruption. This was accomplished by exposing the iliac lumen to the chemotactic agent fMLP (1 μM; n = 6 pigs), concomitant heparinase III (100 mU ml−1) and hyaluronidase (14 mg ml−1) (n = 4), and neuraminidase (140 mU ml−1; n = 5), for 20 min in separate...
Mon Mar 02, 2020 02:00
Video surveys were carried out during the 75th cruise of the RV Akademik M.A. Lavrentyev (June 2016) along the northern slope of the Volcanologists Massif, in the south-western Bering Sea. The seafloor was explored using the ROV Comanche 18. Seven dives were performed in the depth range from 4,278 m to 349 m. Overall, about 180 species of megafauna were recognised. Fifteen types of megafauna communities corresponding to certain depth ranges were distinguished based on the most abundant taxa. Dominance...
Mon Mar 02, 2020 02:00
Cassava is a staple food crop in sub-Saharan Africa; it is a rich source of carbohydrates and proteins which currently supports livelihoods of more than 800 million people worldwide. However, its continued production is at stake due to vector-transmitted diseases such as Cassava mosaic disease and Cassava brown streak disease. Currently, the management and control of viral diseases in cassava relies mainly on virus-resistant cultivars of cassava. Thus, the discovery of new target genes for plant...
Mon Mar 02, 2020 02:00
Birdwatching is a very popular and increasing leisure activity, and the study and observation of birds is more popular in the morning due to the greater activity among birds at that time of day. The aim of our study was to find out whether there was a relationship between the circadian preference of observers and their favourite bird species and whether it was influenced by such factors as professional status, age and gender. In an e-mail survey we asked a total of 433 Polish ornithologists (professionals)...
Mon Mar 02, 2020 02:00
Permineralized peat from the central Transantarctic Mountains of Antarctica has provided a wealth of information on plant and fungal diversity in Middle Triassic high-latitude forest paleoecosystems; however, there are no reports as yet of algae or cyanobacteria. The first record of a fossil filamentous cyanobacterium in this peat consists of wide, uniseriate trichomes composed of discoid cells up to 25 µm wide, and enveloped in a distinct sheath. Filament morphology, structurally preserved by permineralization...
Mon Mar 02, 2020 02:00
Managing low-grade gliomas (LGG) remains a major medical challenge due to the infiltrating nature of the tumor and failure of surgical resection to eliminate the disease. EMILIN/Multimerins contain the gC1q signature, which is involved in many tumor processes. However, the expression and prognostic value of EMILIN/Multimerins in LGG remains unclear. This study used integrated bioinformatics analysis to investigate the expression pattern, prognostic value and function of EMILIN/Multimerins in patients...
Mon Mar 02, 2020 02:00
Cephalanthera rubra (L.) Rich., Red Helleborine, is a widespread orchid in Europe but known only from three very small populations in England. These populations are in decline with no natural seed setting for more than a decade. The species may become extinct in the UK soon unless viable strategies are in place for ex situ conservation, especially the use of symbiotic propagation. Because of the fragile nature of the populations in England mycorrhizal fungal diversity study is not feasible. Therefore,...
Mon Mar 02, 2020 02:00
Purpose Erectile dysfunction (ED) is one of the most common male-disease globally. Despite efforts to explain its pathogenesis, the molecular mechanisms of ED are still not well understood. Methods The microarray dataset GSE10804 was downloaded from the Gene Expression Omnibus (GEO) to find candidate genes in ED progression. After differentially expressed genes (DEGs) were identified, functional enrichment analysis was...
Fri Feb 28, 2020 02:00
Background Citizen science is increasingly popular and has the potential to collect extensive datasets at lower costs than traditional surveys conducted by professional scientists. Ferries have been used to collect data on cetacean populations for decades, providing long-term time series for monitoring of cetacean populations. One cetacean species of concern is the common dolphin, which has been found stranded around the north-east Atlantic in recent years, with high numbers on French coasts being...
Fri Feb 28, 2020 02:00
Profiling cellular phenotypes from microscopic imaging can provide meaningful biological information resulting from various factors affecting the cells. One motivating application is drug development: morphological cell features can be captured from images, from which similarities between different drug compounds applied at different doses can be quantified. The general approach is to find a function mapping the images to an embedding space of manageable dimensionality whose geometry captures relevant...
Fri Feb 28, 2020 02:00
Background Ecological communities of interacting species analyzed as complex networks have shown that species dependence on their counterparts is more complex than expected at random. As for other potentially mutualistic interactions, ant-plant networks mediated by extrafloral nectar show a nested (asymmetric) structure with a core of generalist species dominating the interaction pattern. Proposed factors structuring ecological networks include encounter probability (e.g., species...
Fri Feb 28, 2020 02:00
Background Fatigue influences athletic performance and can also increase the risk of injury in sports, and most of the methods to evaluate it require an additional voluntary effort. Tensiomyography (TMG), which uses electrical stimulation and a displacement sensor to evaluate muscle contraction properties of one or more muscle bellies, has emerged as a technique that can assess the presence of peripheral and central fatigue without requiring additional voluntary efforts. However,...
Fri Feb 28, 2020 02:00
High-altitude ecosystems are found in mountain chains and plateaus worldwide. These areas tend to be underrepresented in insect biodiversity assessments because of the challenges related to systematic survey at these elevations, such as extreme climatic and geographic conditions. Nonetheless, high-altitude ecosystems are of paramount importance because they have been seen to be species pumps for other geographic areas, such as adjacent locations, functioning as buffers for population declines. Moreover,...
Fri Feb 28, 2020 02:00
Abstract Measurement of alcohol use and associated harms at the city level is often incomplete or non-existent even though such data are often critical to informing local prevention strategies. This paper models how to generate local estimates of the morbidity, mortality, and cost of current alcohol use instead of abstaining. Administrative data sources, including medical examiner records, hospital records, and police records, among others, were used to obtain local estimates of...
Mon Mar 02, 2020 02:00
Abstract Purpose d-psicose-3-epimerase (DPEase) catalyses the isomerisation of d-fructose to d-psicose, a rare sugar in nature with unique nutritional and biological functions. An effective industrial-scale method is needed for d-psicose production. Herein, the expression of a neutral and a slightly acidic pH DPEase in Bacillus subtilis was evaluated. Methods ...
Mon Mar 02, 2020 02:00
Abstract Purpose The aim of the present study was to investigate the tolerance of five new Achromobacter and Pseudomonas strains to kerosene and to establish if the production of several secondary metabolites increases or not when these bacteria were grown in the presence of kerosene. The biodegradation of kerosene by isolated bacteria was also investigated in this study. ...
Mon Mar 02, 2020 02:00
Abstract Recent studies have shown that the level of miR-1202 in peripheral blood is closely related to brain activity and cognitive function in patients with depression, and it is involved in glioma pathological progress. However, the correlation between miR-1202 and neuroinflammation has not been reported. The expressions of miR-1202 and small GTP-ase Rab1a at mRNA level were detected in oxygen-glucose deprivation (OGD)/reoxygenation (R) induced human microglial cells (HM cells)...
Mon Mar 02, 2020 02:00
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