(Washington State University) The average age at which teens and young adults start using drugs has been rising, according to a study published in JAMA Pediatrics. The study examined changes in the average age of first drug use for 18 different drugs--including alcohol and tobacco products--between 2004 and 2017 and found that average ages had increased for the majority of those drugs.
(Lindau Nobel Laureate Meetings) - Confirmations for the invitation to the 70th Meeting sent out today- Network of academic partners expanded again- Selection process supported by alumni of previous Meetings- Application for the 71st Lindau Meeting 2021 from September- Further information available at lindau-nobel.org - #LINO70
(University of Helsinki) A new research from the University of Helsinki showed for the first time how the pre-immunization acquired through common childhood vaccines can be used to enhance therapeutic cancer treatment.
(Massachusetts Institute of Technology) A study from MIT and Brown University reveals a neural circuit that appears to underlie sensory hypersensitivity in a mouse model of autism, offering a possible strategy for developing new treatments.
(University of Zurich) At high species richness, directed loss, but not random loss, of tree species strongly decreases forest productivity. This is shown by data from a big forest project in China in which the University of Zurich is involved. Previous studies based on random species loss could therefore bias the predictions of how more realistic extinction scenarios are likely to affect ecosystem functioning.
(Hubrecht Institute) Researchers from the group of Hans Clevers at the Hubrecht Institute have developed a new genetic tool to label specific genes in human organoids, or mini organs. They used this new method, called CRISPR-HOT, to investigate how hepatocytes divide and how abnormal cells with too much DNA appear. By disabling the cancer gene TP53, they showed that unstructured divisions of abnormal hepatocytes were more frequent, which may contribute to cancer development.
(John Innes Centre) A study published in Nature Plants, led by scientists from the John Innes Centre in the UK and the University of Toulouse/CNRS in France, describes the discovery of a common genetic basis for plant symbioses
(University of Southampton) A study led by the University of Southampton, funded by Cancer Research UK, has shown a new drug -- originally developed to tackle the scarring of organ tissue -- could help to significantly improve the success rate of cancer immunotherapy treatment.
(IOP Publishing) Researchers in the US have developed a new multi-organ-on-a-chip to test how new drugs affect the human body's vital organs.Developing new drugs can come at enormous financial cost, which can be wasted if the drug must be withdrawn due to unforeseen side effects. The research team believes their new system -- containing representations of liver, heart, vasculature, lungs, testis, and either colon or brain tissues -- could help avoid such cases.
(National Research University Higher School of Economics) The scope of childhood malnutrition has decreased since 2000, although millions of children under five years of age are still undernourished and, as a result, have stunted growth. An international team of researchers analyzed the scope of global childhood malnutrition in 2000 and 2017, and estimated the probability of achieving the World Health Organization Global Nutrition Targets by 2025.
(JAMA Network) Researchers investigated pay differences by sex at the highest ranks of academic medicine among clinical department chairs at 29 state medical schools in 12 states.
(Karolinska Institutet) Researchers from Karolinska Institutet in Sweden have together with an international team mapped the relationship between length of pregnancy and chemical DNA changes in more than 6,000 newborn babies. For each week's longer pregnancy, DNA methylation changes in thousands of genes were detected in the umbilical cord blood. The study is published in Genome Medicine.
(Max Planck Institute for the Science of Human History) By analyzing milk proteins extracted from calcified dental plaque, researchers from the Max Planck Institute for the Science of Human History and their international partners present the earliest evidence for dairy consumption on the eastern Eurasian Steppe and uncover clues to the origin of mounted dairy pastoralism in Mongolia.
(NIH/National Institute on Aging) Researchers report an advance in the development of a blood test that could help detect pathological Alzheimer's disease in people who are showing signs of dementia. This approach could be less invasive and less costly than current brain imaging and spinal fluid tests. The study, funded by the National Institutes of Health, was published on March 2 in Nature Medicine.
(Brigham and Women's Hospital) A new study led by investigators from Brigham and Women's Hospital measured participants' sleep duration and timing, finding that over a five-year period, individuals who had the most irregular sleep experienced a two-fold increased risk of developing cardiovascular disease compared to those with the most regular sleep patterns.
(University of Science and Technology of China) Researchers found CRF responsible for stress coping.
(Pacific Institute for Research and Evaluation) A new study led by researchers at the Prevention Research Center of the Pacific Institute for Research and Evaluation explores these questions using real time data from 100 youth participants from 16-20 years old to assess the effect of exposure to tobacco outlets on same-day smoking and the number of cigarettes consumed.
(University of British Columbia Okanagan campus) Professor Kathleen Martin Ginis says a major barrier to physical activity for people with a spinal cord injury is a lack of knowledge or resources about the amount and type of activity needed to achieve health and fitness benefits.
(King's College London) An improved mobile phone app will help identify women who need special treatments at the right time and reduce emotional and financial burden on families and the NHS.
(Karolinska Institutet) Researchers at Karolinska Institutet in Sweden have analysed all cell types in the human ovary and found that the hotly debated so-called egg stem cells do not exist. The results, published in Nature Communications, open the way for research on improved methods of treating involuntary childlessness.
(University of Texas at San Antonio) Scientists think that a person's values may shape views on "socially appropriate sickness." This has implications for how individuals may take more action in dealing with illness rather than spreading further disease. According to the researchers, stoics or individuals with incomes lower than $60,000 were more likely to claim being ill. People may be comfortable reporting being sick when it's a common cold but questions arise with stigmatized infections, such...
(American Academy of Sleep Medicine) Artificial intelligence has the potential to improve efficiencies and precision in sleep medicine, resulting in more patient-centered care and better outcomes, according to a new position statement from the American Academy of Sleep Medicine.
(University of Exeter) Cases of potentially deadly brain damage as a result of stroke could be reduced after new research identified a pathway in the brain that causes swelling, and which responds to an innovative treatment.
(Mayo Clinic) Chronic pain affects a large proportion of older adults and most long-term care residents. Managing chronic pain effectively is essential but challenging, and it has been complicated by concerns about opioid abuse.
(Canadian Medical Association Journal) A practice article provides 5 things to know on how drugs can interact with cannabinoids in CMAJ (Canadian Medical Association Journal).
(Canadian Medical Association Journal) Innovative, Indigenous-led health care partnerships and cultural healing practices have shown improved health outcomes and access to care, and have become important features of the medical landscape in Canada, according to a new analysis in CMAJ (Canadian Medical Association Journal).
(Canadian Medical Association Journal) As Canada's population grows and ages, the cancer burden will remain high and even increase in 2020, according to a study on projected cancer rates published in CMAJ (Canadian Medical Association Journal).
(University of Manchester) Epidemiologists at the University of Manchester have discovered an association between the number of prescriptions for antibiotics and a higher risk of hospital admissions.
(Parkinson's UK) Results from a study looking at an experimental drug to tackle the debilitating side effect of dyskinesia, have offered hope that it may have potential as a future treatment for people with Parkinson's.
(University of East Anglia) Omega-3 fats do not protect against cancer -- according to new University of East Anglia research. Increased consumption of omega-3 fats is widely promoted globally because of a common belief that it will protect against, or even reverse, diseases such as cancer, heart attacks and stroke. But two systematic reviews find that omega-3 supplements may slightly reduce coronary heart disease mortality and events, but slightly increase risk of prostate cancer. Both beneficial...
(Umea University) The cruise ship Diamond Princess was quarantined for over two weeks resulting in more coronavirus infected passengers than if they would have disembarked immediately. Rather the opposite to what was intended. This according to a study conducted at Umeå University in Sweden.
(University of Connecticut) Doctors used to make patients with drug-induced liver injury stop taking all their medications until the liver healed, but this could be dangerous. Now, researchers report in two recent papers that people with diabetes, hypertension and depression might be able to continue taking life saving medications even while they heal from drug-induced liver injuries.
(University of Warwick) Virtual reality could help physiotherapy patients complete their exercises at home successfully thanks to researchers at WMG, University of Warwick, who managed to combine VR technology with 3D motion capture.
(NIH/National Institute of Allergy and Infectious Diseases) The emergence and rapid increase in cases of coronavirus disease 2019 (COVID-19), a respiratory illness caused by a novel coronavirus, pose complex challenges to the global public health, research and medical communities, write federal scientists from NIH's National Institute of Allergy and Infectious Diseases (NIAID) and from the Centers for Disease Control and Prevention (CDC). Their commentary appears in The New England Journal of Medicine.
(American Roentgen Ray Society) Although COVID-19's imaging features are variable and nonspecific, the findings thus far do show "significant overlap" with those of severe acute respiratory syndrome and Middle East respiratory syndrome. According to AJR, the early evidence suggests that initial chest imaging will show abnormality in at least 85% of patients, with 75% of patients having bilateral lung involvement initially that most often manifests as subpleural and peripheral areas of ground-glass...
(Johannes Gutenberg Universitaet Mainz) As part of the German government's 2025 High-Tech Strategy, the German Federal Ministry of Education and Research will fund the new interdisciplinary research cluster DIASyM - "Data-Independent Acquisition-based Systems Medicine (DIASyM): Mass Spectrometry for High-Throughput Deep Phenotyping of Heart Failure Syndrome" of the Mainz University Medical Center and Johannes Gutenberg University Mainz with EUR 6.8 million in the first three-year project phase. DIASyM...
(National Foundation for Cancer Research) Michael N. Hall, Ph.D., the National Foundation for Cancer Research's (NFCR) 2017 Szent-Györgyi Prize for Progress in Cancer Research winner, and David Sabatini, M.D., Ph.D., were named winners of the 2020 Sjöberg Prize, which honors cancer research excellence. Doctor Hall becomes the third winner of the Szent-Györgyi Prize, one of the most prestigious awards in cancer research, to subsequently be selected for the Sjöberg Prize.
(National Institute for Health Research) Researchers at the Universities of Leicester and Nottingham have discovered parts of the DNA that put some people at higher risk of an incurable lung disease called idiopathic pulmonary fibrosis (IPF). The findings are published in the American Journal of Respiratory and Critical Care Medicine today.
(Oregon Health & Science University) Pregnancies among women with disabilities are 42% more likely to be unintended than pregnancies among women without disabilities, says a new report published in the journal Perspectives on Sexual and Reproductive Health.
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