Stem Cells and Development, Ahead of Print.
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A new hexavalent vaccine for use in children aged 6 weeks through 4 years has been approved by the FDA to prevent diphtheria, tetanus, pertussis, polio, Haemophilus influenzae type b, and hepatitis B.Morbidity & Mortality Weekly Report (Source: Medscape Allergy Headlines)
Pediatric-onset patients show features different to those with adult onset that may help clinicians with management, new research suggests.Medscape Medical News (Source: Medscape Allergy Headlines)
A new study shows patients with multiple sclerosis are at increased risk for most infections, particularly renal tract infections.Medscape Medical News (Source: Medscape Allergy Headlines)
Aaron Holley, MD, calls for more attention to the role of behavioral health in the clinical practice of asthma.Medscape Critical Care (Source: Medscape Allergy Headlines)
Clinicians can help lead the way in COVID-19 preparedness by fighting pandemic denial in themselves and being frank with their patients, an expert in risk communication said.Medscape Medical News (Source: Medscape Allergy Headlines)
Parents of children with food allergies should acknowledge their kids'anxiety, as well as their own, a group of allergy experts advises.Reuters Health Information (Source: Medscape Allergy Headlines)
Two Chinese nurses on the frontlines of the coronavirus outbreak in the city of Wuhan made an unusual global appeal for help in a letter published by a prestigious British medical journal.Reuters Health Information (Source: Medscape Allergy Headlines)
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Healthcare database studies can be complicated. The data itself can be complex. Raw data needs to be transformed into useful variables. Then this analytic file needs to evaluated in an appropriate manner. Plus, the results need to be communicated clearly. What are the key aspects for describing this approach both among members of the research team and to external stakeholders (e.g., journal reviewers and editors). A paper by Wang et al. (2017) provides a nice overview of the components...
According to a paper by Stevens et al. (2020), the answer is ‘yes’. One clear reason why it would change is if the drug’s price changes. Even if that is not the case, however, the drug may be more or less effective over time. For instance, physicians may improve their ability to manage side effects or target dosing to specific patients. The authors call this the impact of “learning by doing”. Using SEER-Medicare data, the authors: …estimated the time‐varying effects of treatments in...
All praise the fist bump.Problems with U.S. coronavirus testing protocols.Health Affairs’ ACA at 10 series.Living with multiple sclerosis.Which programming language is best for economics research?
No, that is not a typo. The cost of Bernie Sanders Medicare-for-All (M4A) plan is $13 trillion dollars. How does this stack up to other candidates? The Committee for a Responsible Federal Budget does the math. Whereas Mr. Sanders plan would cost $12.95 trillion between 2021 and 2030, Mrs. Warren’s plan would cost $6.1 trillion, still expensive but half of the Sanders plan. Mr. Biden’s health care plan would increase federal deficits by only $0.8 trillion, whereas the Buttigieg plan would...
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Blood Cancer Journal, Published online: 02 March 2020; doi:10.1038/s41408-020-0297-2Consolidation with carfilzomib, lenalidomide, and dexamethasone (KRd) following ASCT results in high rates of minimal residual disease negativity and improves bone metabolism, in the absence of bisphosphonates, among newly diagnosed patients with multiple myeloma
Blood Cancer Journal, Published online: 28 February 2020; doi:10.1038/s41408-020-0288-3Mass spectrometry-based identification of a B-cell maturation antigen-derived T-cell epitope for antigen-specific immunotherapy of multiple myeloma
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Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
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Abstract Introduction We used data from MOBI-Kids, a 14-country international collaborative case–control study of brain tumors (BTs), to study clinical characteristics of the tumors in older children (10 years or older), adolescents and young adults (up to the age of 24). Methods Information from clinical records was obtained for 899 BT cases, including signs...
Abstract Introduction Opening of the blood–brain barrier (BBB) by pulsed low intensity ultrasound has been developed during the last decade and is now recognized as a safe technique to transiently and repeatedly open the BBB. This non- or minimally invasive technique allows for a targeted and uniform dispersal of a wide range of therapeutic substances throughout the brain, including immune cells and antibodies. ...
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Abstract Micropigmentation, also termed medical tattooing, can be a useful alternative treatment for patients with vitiligo who are resistant to conventional treatments. To assess the benefits and risks of micropigmentation in the treatment of refractory vitiligo, 25 lesions of 14 patients with vitiligo (Fitzpatrick skin types III and IV) were subjected to micropigmentation using an electric tattooing machine between December 2018 and March 2019. The procedure was repeated until satisfactory results...
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(Oxford University Press USA) A new study in the Journal of the National Cancer Institute finds improvements in five-year survival rates for all cancers in young adults. For some cancers, however, there has been little improvement since the 1970s.
(Boston University School of Medicine) For people living with HIV, any level of alcohol consumption is associated with lower levels of a protein involved in bone formation, raising the risk of osteoporosis, according to a new study by researchers from the Boston University School of Public Health (BUSPH) and School of Medicine (BUSM) and published in the journal Alcoholism: Clinical and Experimental Research.
(The Lancet) Patients with molecular changes in their tumors who received a targeted therapy alongside other treatment survived for an average of one year longer after being diagnosed with advanced disease compared with patients who received standard chemotherapy (survival of 31 vs. 18 months), according to an observational study published in The Lancet Oncology journal.
(Oregon Health & Science University) New direct-acting antiviral therapies are highly effective at eliminating the Hepatitis C virus infection, according to a systematic evidence review by researchers at Oregon Health & Science University. The review, published today in the Journal of the American Medical Association, informed a new recommendation by the U.S. Preventive Health Task Force for universal screening of Hepatitis C
(Colorado State University) Most people know that good oral hygiene - brushing, flossing, and regular dental visits - is linked to good health. Colorado State University microbiome researchers offer fresh evidence to support that conventional wisdom, by taking a close look at invisible communities of microbes that live in every mouth. Their study found a correlation between people who did not visit the dentist regularly and increased presence of a pathogen that causes periodontal disease.
(University of Illinois at Urbana-Champaign, News Bureau) Novel biomedical advances that show promise in the lab often fall short in clinical trials. For researchers studying peripheral artery disease, this is made more difficult by a lack of standardized metrics for what recovery looks like. A new study from University of Illinois at Urbana-Champaign researchers identifies major landmarks of PAD recovery, creating signposts for researchers seeking to understand the disease and develop treatments.
(Mayo Clinic) A study by researchers at Mayo Clinic published this week in the Journal of Clinical Oncology suggests that all women with a breast cancer diagnosis under the age of 66 be offered germline genetic testing to determine if they have a gene mutation known to increase the risk of developing other cancers and cancers among blood relatives.
(Thomas Jefferson University) The advanced technology has the potential to change acute stroke treatment.
(Emory Health Sciences) Within hours of birth, a baby's gaze is drawn to faces. Now, brain scans of newborns reveal the neurobiology underlying this behavior, showing that as young as six days old a baby's brain appears hardwired for the specialized tasks of seeing faces and seeing places.
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