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Δευτέρα 2 Μαρτίου 2020


Keratinocytes Derived from Patient-Specific Induced Pluripotent Stem Cells Recapitulate the Genetic Signature of Psoriasis Disease
Stem Cells and Development, Ahead of Print.
Stem Cells and Development
Mon Mar 02, 2020 10:00
Licensure of a New Hexavalent Vaccine for Use in Infants Licensure of a New Hexavalent Vaccine for Use in Infants
A new hexavalent vaccine for use in children aged 6 weeks through 4 years has been approved by the FDA to prevent diphtheria, tetanus, pertussis, polio, Haemophilus influenzae type b, and hepatitis B.Morbidity & Mortality Weekly Report (Source: Medscape Allergy Headlines)
Medscape Allergy Headlines
Mon Mar 02, 2020 16:05
Key Differences Found Between Pediatric- and Adult-Onset MS Key Differences Found Between Pediatric- and Adult-Onset MS
Pediatric-onset patients show features different to those with adult onset that may help clinicians with management, new research suggests.Medscape Medical News (Source: Medscape Allergy Headlines)
Medscape Allergy Headlines
Mon Mar 02, 2020 15:36
Increased Risk of Infection Seen in Patients With MS Increased Risk of Infection Seen in Patients With MS
A new study shows patients with multiple sclerosis are at increased risk for most infections, particularly renal tract infections.Medscape Medical News (Source: Medscape Allergy Headlines)
Medscape Allergy Headlines
Sat Feb 29, 2020 06:14
Exposing the Role of Psychosocial Stress on Asthma Exposing the Role of Psychosocial Stress on Asthma
Aaron Holley, MD, calls for more attention to the role of behavioral health in the clinical practice of asthma.Medscape Critical Care (Source: Medscape Allergy Headlines)
Medscape Allergy Headlines
Fri Feb 28, 2020 17:09
COVID-19 Preparedness: Clinicians Can Lead the Way COVID-19 Preparedness: Clinicians Can Lead the Way
Clinicians can help lead the way in COVID-19 preparedness by fighting pandemic denial in themselves and being frank with their patients, an expert in risk communication said.Medscape Medical News (Source: Medscape Allergy Headlines)
Medscape Allergy Headlines
Fri Feb 28, 2020 01:56
Allergists Offer Advice to Parents of Kids With Food Allergies Allergists Offer Advice to Parents of Kids With Food Allergies
Parents of children with food allergies should acknowledge their kids'anxiety, as well as their own, a group of allergy experts advises.Reuters Health Information (Source: Medscape Allergy Headlines)
Medscape Allergy Headlines
Thu Feb 27, 2020 22:06
Two Chinese Nurses Call for Overseas Help in Stretched Virus Wards Two Chinese Nurses Call for Overseas Help in Stretched Virus Wards
Two Chinese nurses on the frontlines of the coronavirus outbreak in the city of Wuhan made an unusual global appeal for help in a letter published by a prestigious British medical journal.Reuters Health Information (Source: Medscape Allergy Headlines)
Medscape Allergy Headlines
Thu Feb 27, 2020 20:59
Improving the transparency of healthcare database study design
Healthcare database studies can be complicated. The data itself can be complex. Raw data needs to be transformed into useful variables. Then this analytic file needs to evaluated in an appropriate manner. Plus, the results need to be communicated clearly. What are the key aspects for describing this approach both among members of the research team and to external stakeholders (e.g., journal reviewers and editors). A paper by Wang et al. (2017) provides a nice overview of the components...
Healthcare Economist
07:34
Does a drug’s cost-effectiveness improve over time?
According to a paper by Stevens et al. (2020), the answer is ‘yes’. One clear reason why it would change is if the drug’s price changes. Even if that is not the case, however, the drug may be more or less effective over time. For instance, physicians may improve their ability to manage side effects or target dosing to specific patients. The authors call this the impact of “learning by doing”. Using SEER-Medicare data, the authors: …estimated the time‐varying effects of treatments in...
Healthcare Economist
Mon Mar 02, 2020 06:41
Friday Links
All praise the fist bump.Problems with U.S. coronavirus testing protocols.Health Affairs’ ACA at 10 series.Living with multiple sclerosis.Which programming language is best for economics research?
Healthcare Economist
Sat Feb 29, 2020 00:15
Cost of Bernie Sanders’ M4A Plan: $13 trillion
No, that is not a typo. The cost of Bernie Sanders Medicare-for-All (M4A) plan is $13 trillion dollars. How does this stack up to other candidates? The Committee for a Responsible Federal Budget does the math. Whereas Mr. Sanders plan would cost $12.95 trillion between 2021 and 2030, Mrs. Warren’s plan would cost $6.1 trillion, still expensive but half of the Sanders plan. Mr. Biden’s health care plan would increase federal deficits by only $0.8 trillion, whereas the Buttigieg plan would...
Healthcare Economist
Fri Feb 28, 2020 09:53
Consolidation with carfilzomib, lenalidomide, and dexamethasone (KRd) following ASCT results in high rates of minimal residual disease negativity and improves bone metabolism, in the absence of bisphosphonates, among newly diagnosed patients with multiple myeloma
Blood Cancer Journal, Published online: 02 March 2020; doi:10.1038/s41408-020-0297-2Consolidation with carfilzomib, lenalidomide, and dexamethasone (KRd) following ASCT results in high rates of minimal residual disease negativity and improves bone metabolism, in the absence of bisphosphonates, among newly diagnosed patients with multiple myeloma
Blood Cancer Journal - Issue - nature.com science feeds
Mon Mar 02, 2020 02:00
Mass spectrometry-based identification of a B-cell maturation antigen-derived T-cell epitope for antigen-specific immunotherapy of multiple myeloma
Blood Cancer Journal, Published online: 28 February 2020; doi:10.1038/s41408-020-0288-3Mass spectrometry-based identification of a B-cell maturation antigen-derived T-cell epitope for antigen-specific immunotherapy of multiple myeloma
Blood Cancer Journal - Issue - nature.com science feeds
Fri Feb 28, 2020 02:00
Circ_0000388 Exerts Oncogenic Function in Cervical Cancer Cells by Regulating miR-337-3p/TCF12 Axis
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Cancer Biotherapy & Radiopharmaceuticals - Table of Contents
Mon Mar 02, 2020 10:00
LncRNA NR2F2-AS1 Upregulates Rac1 to Increase Cancer Stemness in Clear Cell Renal Cell Carcinoma
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Cancer Biotherapy & Radiopharmaceuticals - Table of Contents
Fri Feb 28, 2020 10:00
LncRNA MACC1-AS1 Promotes Lung Adenocarcinoma Cell Proliferation by Downregulating PTEN
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Cancer Biotherapy & Radiopharmaceuticals - Table of Contents
Fri Feb 28, 2020 10:00
Labeling Monoclonal Antibody with α-emitting 211At at High Activity Levels via a Tin Precursor
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Cancer Biotherapy & Radiopharmaceuticals - Table of Contents
Fri Feb 28, 2020 10:00
The Relationship Between Total Lesion Activity on 18F Choline Positron Emission Tomography-Computed Tomography and Clinical Outcome in Patients with Castration-Resistant Prostate Cancer Bone Metastases Treated with 223Radium
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Cancer Biotherapy & Radiopharmaceuticals - Table of Contents
Fri Feb 28, 2020 10:00
Clinical presentation of young people (10–24 years old) with brain tumors: results from the international MOBI-Kids study
Abstract Introduction We used data from MOBI-Kids, a 14-country international collaborative case–control study of brain tumors (BTs), to study clinical characteristics of the tumors in older children (10 years or older), adolescents and young adults (up to the age of 24). Methods Information from clinical records was obtained for 899 BT cases, including signs...
Latest Results for Journal of Neuro-Oncology
02:00
Blood–brain barrier opening with low intensity pulsed ultrasound for immune modulation and immune therapeutic delivery to CNS tumors
Abstract Introduction Opening of the blood–brain barrier (BBB) by pulsed low intensity ultrasound has been developed during the last decade and is now recognized as a safe technique to transiently and repeatedly open the BBB. This non- or minimally invasive technique allows for a targeted and uniform dispersal of a wide range of therapeutic substances throughout the brain, including immune cells and antibodies. ...
Latest Results for Journal of Neuro-Oncology
Fri Feb 28, 2020 02:00
Micropigmentation for vitiligo on light to moderately colored skin: Updated evidence from a clinical and animal study
Abstract Micropigmentation, also termed medical tattooing, can be a useful alternative treatment for patients with vitiligo who are resistant to conventional treatments. To assess the benefits and risks of micropigmentation in the treatment of refractory vitiligo, 25 lesions of 14 patients with vitiligo (Fitzpatrick skin types III and IV) were subjected to micropigmentation using an electric tattooing machine between December 2018 and March 2019. The procedure was repeated until satisfactory results...
The Journal of Dermatology
07:35
Squamous cell carcinoma of the nose presenting with a giant cutaneous horn: A unique clinical presentation
The Journal of Dermatology
07:35
Tissue resident memory T cells in lesional and non‐lesional psoriatic skin on a scar
The Journal of Dermatology
07:35
Anemia in a psoriatic patient treated with ixekizumab
The Journal of Dermatology
07:35
Cancer survival rates improve for young adults
(Oxford University Press USA) A new study in the Journal of the National Cancer Institute finds improvements in five-year survival rates for all cancers in young adults. For some cancers, however, there has been little improvement since the 1970s.
EurekAlert! - Medicine and Health
07:00
Drinking weakens bones of people living with HIV: BU study
(Boston University School of Medicine) For people living with HIV, any level of alcohol consumption is associated with lower levels of a protein involved in bone formation, raising the risk of osteoporosis, according to a new study by researchers from the Boston University School of Public Health (BUSPH) and School of Medicine (BUSM) and published in the journal Alcoholism: Clinical and Experimental Research.
EurekAlert! - Medicine and Health
07:00
The Lancet Oncology: Targeted treatments for pancreatic cancer may help eligible patients live an extra year
(The Lancet) Patients with molecular changes in their tumors who received a targeted therapy alongside other treatment survived for an average of one year longer after being diagnosed with advanced disease compared with patients who received standard chemotherapy (survival of 31 vs. 18 months), according to an observational study published in The Lancet Oncology journal.
EurekAlert! - Medicine and Health
Mon Mar 02, 2020 07:00
OHSU-led evidence review shows new therapy for Hepatitis C is highly effective
(Oregon Health & Science University) New direct-acting antiviral therapies are highly effective at eliminating the Hepatitis C virus infection, according to a systematic evidence review by researchers at Oregon Health & Science University. The review, published today in the Journal of the American Medical Association, informed a new recommendation by the U.S. Preventive Health Task Force for universal screening of Hepatitis C
EurekAlert! - Medicine and Health
Mon Mar 02, 2020 07:00
The microbes in your mouth, and a reminder to floss and go to the dentist
(Colorado State University) Most people know that good oral hygiene - brushing, flossing, and regular dental visits - is linked to good health. Colorado State University microbiome researchers offer fresh evidence to support that conventional wisdom, by taking a close look at invisible communities of microbes that live in every mouth. Their study found a correlation between people who did not visit the dentist regularly and increased presence of a pathogen that causes periodontal disease.
EurekAlert! - Medicine and Health
Mon Mar 02, 2020 07:00
Study maps landmarks of peripheral artery disease to guide treatment development
(University of Illinois at Urbana-Champaign, News Bureau) Novel biomedical advances that show promise in the lab often fall short in clinical trials. For researchers studying peripheral artery disease, this is made more difficult by a lack of standardized metrics for what recovery looks like. A new study from University of Illinois at Urbana-Champaign researchers identifies major landmarks of PAD recovery, creating signposts for researchers seeking to understand the disease and develop treatments.
EurekAlert! - Medicine and Health
Mon Mar 02, 2020 07:00
Mayo researchers recommend all women with breast cancer diagnosis under age 66
(Mayo Clinic) A study by researchers at Mayo Clinic published this week in the Journal of Clinical Oncology suggests that all women with a breast cancer diagnosis under the age of 66 be offered germline genetic testing to determine if they have a gene mutation known to increase the risk of developing other cancers and cancers among blood relatives.
EurekAlert! - Medicine and Health
Mon Mar 02, 2020 07:00
Novel use of robotics for neuroendovascular procedures
(Thomas Jefferson University) The advanced technology has the potential to change acute stroke treatment.
EurekAlert! - Medicine and Health
Mon Mar 02, 2020 07:00
Earliest look at newborns' visual cortex reveals the minds babies start with
(Emory Health Sciences) Within hours of birth, a baby's gaze is drawn to faces. Now, brain scans of newborns reveal the neurobiology underlying this behavior, showing that as young as six days old a baby's brain appears hardwired for the specialized tasks of seeing faces and seeing places.
EurekAlert! - Medicine and Health
Mon Mar 02, 2020 07:00

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