(Source: Journal of Gastrointestinal Cancer)
00:00
Conclusions: This large epidemiologic study demonstrates a positive association between current H. pylori infection and the severity of both precancerous and cancerous lesions of the gastric cardia in an Asian population at high risk of GCA. These findings suggest that H. pylori infection may play a role throughout both early- and late-stage development of GCA. (Source: Frontiers in Oncology)
00:00
To support great demand of cell growth, cancer cells preferentially obtain energy and biomacromolecules by glycolysis over mitochondrial oxidative phosphorylation (OxPhos). Among all glycolytic enzymes, hexokinase (HK), a rate-limiting enzyme at the first step of glycolysis to catalyze cellular glucose into glucose-6-phosphate, is herein emphasized. Four HK isoforms, HK1-HK4, were discovered in nature. It was shown that HK2 expression is enriched in many tumor cells and correlated with poorer survival...
00:00
Cancer Gene Therapy, Published online: 03 March 2020; doi:10.1038/s41417-020-0170-2Transcription factors in ferroptotic cell death (Source: Cancer Gene Therapy)
00:00
Conclusion: GPSM2 was an independent prognostic factor in breast cancer and nuclear expression of GPSM2 was significantly associated with poor prognosis, which was related to the positive expression of DYNC1I1. Examination of both GPSM2 and DYNC1I1 is necessary to establish a prognosis in breast cancer patients. (Source: Frontiers in Oncology)
00:00
ConclusionsThis is the largest clinical epidemiology study of BT in young people conducted so far. Many signs and symptoms were identified, dominated by headaches and nausea/vomiting. Diagnosis was generally rapid but in 12% diagnostic delay exceeded 1 year with none of the symptoms been associated with a distinctly long time until diagnosis. (Source: Journal of Neuro-Oncology)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media...
00:00
Conclusions: We proposed an online replanning strategy for automatically correcting interfractional anatomy variations. The preliminary results indicate that the IFP method substantially increased planning speed for online adaptive replanning. (Source: Frontiers in Oncology)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
00:00
ConclusionPerceived self-efficacy was the most salient predictor of the probability of undergoing fecal occult blood testing as well as the history of the test. Promoting perceived self-efficacy is very important in the process of promoting colorectal cancer screening behaviors. Therefore, it is recommended that when designing educational interventions, consideration should be given to enhancing the perceived self-efficacy of at-risk individuals to overcome the barriers for performing fecal occult...
00:00
(Source: OncoTargets and Therapy)
Mon Mar 02, 2020 23:48
(Source: OncoTargets and Therapy)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
Mon Mar 02, 2020 23:40
ACS Applied Materials& InterfacesDOI: 10.1021/acsami.9b20071 (Source: ACS Applied Materials and Interfaces)
Mon Mar 02, 2020 06:00
ACS Applied Materials& InterfacesDOI: 10.1021/acsami.0c00095 (Source: ACS Applied Materials and Interfaces)
Mon Mar 02, 2020 06:00
Pancreatic cancer is currently one of the most lethal diseases. In recent years, increasing evidence has shown that reprogrammed metabolism may play a critical role in the carcinogenesis, progression, treatmen... (Source: Molecular Cancer)
Mon Mar 02, 2020 01:00
As the standard treatments for cancer, chemotherapy and radiotherapy have been widely applied to clinical practice worldwide. However, the resistance to cancer therapies is a major challenge in clinics and sci... (Source: Molecular Cancer)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Mon Mar 02, 2020 01:00
It is well acknowledged that immune system is deeply involved in cancer initiation and progression, and can exert both pro-tumorigenic and anti-tumorigenic effects, depending on specific microenvironment. With... (Source: Molecular Cancer)
Mon Mar 02, 2020 01:00
Glioma is one of the most malignant brain tumors and accounts for the majority of brain cancer related death. Despite progress on mechanistic studies, current understandings of the initiation and progression o... (Source: Cancer Cell International)
Mon Mar 02, 2020 01:00
Pancreatic cancer is a highly lethal disease with a poor prognosis, and existing therapies offer only limited effectiveness. Mutation gene sequencing has shown several gene associations that may account for it... (Source: Molecular Cancer)
Mon Mar 02, 2020 01:00
Genomic imprinting is the differential expression of alleles in diploid individuals, with the expression being dependent upon the sex of the parent from which it was inherited. Haigs kinship theory hypothesizes that genomic imprinting is due to an evolutionary conflict of interest between alleles from the mother and father. In social insects, it has been suggested that genomic imprinting should be widespread. One recent study identified parent-of-origin expression in honeybees and found evidence...
Mon Mar 02, 2020 02:00
While numerous studies have found horizontal transposon transfer (HTT) to be widespread across metazoans, few have focused on HTT in marine ecosystems. To investigate potential recent HTTs into marine species we searched for novel repetitive elements in sea snakes, a group of elapids which transitioned to a marine habitat at most 18 Mya. Our analysis uncovered repeated HTTs into sea snakes following their marine transition. Such major shifts in habitat should require significant genomic changes.The...
Mon Mar 02, 2020 02:00
PARIS--(BUSINESS WIRE)--Regulatory News: GenSight Biologics (Paris:SIGHT) (Euronext: SIGHT, ISIN: FR0013183985, PEA-PME eligible), a biopharma company focused on discovering and developing innovative gene therapies for retinal neurodegenerative diseases and central nervous system disorders, announced today that the bilateral visual recovery observed with GS010 (LUMEVOQ™) in the REVERSE and RESCUE Phase III trials will be presented and discussed at the 46th Annual Meeting of the North American N
08:30
PARIS--(BUSINESS WIRE)--Regulatory News: GenSight Biologics (Paris:SIGHT) (Euronext : SIGHT, ISIN : FR0013183985, éligible PEA-PME), société biopharmaceutique dédiée à la découverte et au développement de thérapies géniques innovantes pour le traitement des maladies neurodégénératives de la rétine et du système nerveux central, annonce aujourd’hui que la récupération visuelle bilatérale observée avec GS010 (LUMEVOQ™) dans les études cliniques de Phase III REVERSE et RESCUE sera présentée et dis
08:30
Everolimus prolongs progression-free survival compared with placebo as long as patients with advanced head and neck cancer remain on it.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
06:23
Isatuximab, in combination with pomalidomide and dexamethasone, has been approved for the treatment of multiple myeloma in patients who have received two or more prior therapies.FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Mon Mar 02, 2020 22:11
(Source: The Doctors Lounge - Oncology)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
Mon Mar 02, 2020 19:00
Hypersomnolence linked to increased risk for developing diabetes, cancer, HTN three years later (Source: The Doctors Lounge - Oncology)
Mon Mar 02, 2020 19:00
(Source: The Doctors Lounge - Oncology)
Mon Mar 02, 2020 11:15
The FDA approved isatuximab-irfc, in combination with pomalidomide and dexamethasone, for the treatment of adult patients with multiple myeloma who have received at least 2 prior therapies, including lenalidomide and a proteasome inhibitor. (Source: CancerNetwork)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
Mon Mar 02, 2020 06:00
The FDA granted priority review to a biologics license application for tafasitamab in combination with lenalidomide for the treatment of patients with relapsed or refractory diffuse large B-cell lymphoma. (Source: CancerNetwork)
Mon Mar 02, 2020 06:00
(European Society of Cardiology) Air pollution is responsible for shortening people's lives worldwide on a scale far greater than wars and other forms of violence, parasitic and insect-born diseases such as malaria, HIV/AIDS and smoking, according to a study published in Cardiovascular Research. (Source: EurekAlert! - Cancer)
Mon Mar 02, 2020 06:00
This study found racial and ethnic disparities in childhood and adolescent cancer survival for non-Hispanic black, non-Hispanic American Indian/Alaskan Native, non-Hispanic Asian or Pacific Islander, and Hispanic patients. (Source: CancerNetwork)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
Mon Mar 02, 2020 06:00
(The Lancet) Patients with molecular changes in their tumors who received a targeted therapy alongside other treatment survived for an average of one year longer after being diagnosed with advanced disease compared with patients who received standard chemotherapy (survival of 31 vs. 18 months), according to an observational study published in The Lancet Oncology journal. (Source: EurekAlert! - Cancer)
Mon Mar 02, 2020 06:00
An interim analysis of the ongoing phase Ib study of resiniferatoxin, administered via epidural route in patients with intractable cancer pain, has produced positive data. (Source: CancerNetwork)
Mon Mar 02, 2020 06:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου