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Δευτέρα 2 Μαρτίου 2020


Manual and automated Cu-mediated radiosynthesis of the PARP inhibitor [18F]olaparib
Health sciences : nature.com subject feeds
Fri Feb 28, 2020 02:00
Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2
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Fri Feb 28, 2020 02:00
Microbial defence against cancer
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Fri Feb 28, 2020 02:00
Layer-specific sensory processing impairment in the primary somatosensory cortex after motor cortex infarction
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Fri Feb 28, 2020 02:00
The multiplex model of the genetics of Alzheimer’s disease
Health sciences : nature.com subject feeds
Fri Feb 28, 2020 02:00
Backchat: Covering coronavirus
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Fri Feb 28, 2020 02:00
Neuron-specific analysis of histone modifications with post-mortem brains
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Fri Feb 28, 2020 02:00
CD28/4-1BB CD123 CAR T cells in blastic plasmacytoid dendritic cell neoplasm
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Fri Feb 28, 2020 02:00
Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response
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Fri Feb 28, 2020 02:00
Genome-wide association and multi-omic analyses reveal ACTN2 as a gene linked to heart failure
Health sciences : nature.com subject feeds
Fri Feb 28, 2020 02:00
Development of smart anti-glycan reagents using immunized lampreys
Health sciences : nature.com subject feeds
Fri Feb 28, 2020 02:00
Towards the automatic detection of social biomarkers in autism spectrum disorder: introducing the simulated interaction task (SIT)
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Fri Feb 28, 2020 02:00
Annexin A5 as an immune checkpoint inhibitor and tumor-homing molecule for cancer treatment
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Fri Feb 28, 2020 02:00
Identification of significant gene biomarkers of low back pain caused by changes in the osmotic pressure of nucleus pulposus cells
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Fri Feb 28, 2020 02:00
No association of complement mannose-binding lectin deficiency with cardiovascular disease in patients with Systemic Lupus Erythematosus
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Fri Feb 28, 2020 02:00
Treatment outcomes in acute invasive fungal rhinosinusitis extending to the extrasinonasal area
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Fri Feb 28, 2020 02:00
Chemotaxis-driven delivery of nano-pathogenoids for complete eradication of tumors post-phototherapy
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Fri Feb 28, 2020 02:00
Shining a light on thyroid eye disease
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Fri Feb 28, 2020 02:00
EPDR1 up-regulation in human colorectal cancer is related to staging and favours cell proliferation and invasiveness
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Fri Feb 28, 2020 02:00
Using empirically-derived dimensional phenotypes to accelerate clinical neuroscience: the Hierarchical Taxonomy of Psychopathology (HiTOP) framework
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Fri Feb 28, 2020 02:00
MRI Radiomic Features: Association with Disease-Free Survival in Patients with Triple-Negative Breast Cancer
Health sciences : nature.com subject feeds
Fri Feb 28, 2020 02:00
Impact of acute kidney injury in elderly versus young deceased donors on post-transplant outcomes: A multicenter cohort study
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Fri Feb 28, 2020 02:00
Development of Oxytolerant Salmonella typhimurium Using Radiation Mutation Technology (RMT) for Cancer Therapy
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Fri Feb 28, 2020 02:00
Structural brain networks in remitted psychotic depression
Health sciences : nature.com subject feeds
Fri Feb 28, 2020 02:00
Loss of angiogenin function is related to earlier ALS onset and a paradoxical increase in ALS duration
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Fri Feb 28, 2020 02:00
Asialo GM1-positive liver-resident CD8 T cells that express CD44 and LFA-1 are essential for immune clearance of hepatitis B virus
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Fri Feb 28, 2020 02:00
Preparation and Characterization of Spherical Submicron CL-20 by Siphon Spray Refinement
In order to improve the safety of hexanitrohexaazaisowurtzitane (CL-20), submicron CL-20 particles were prepared by a siphon ultrasonic-assisted spray refining experimental device. The samples were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), and differential scanning calorimetry (DSC), and the impact sensitivity of the samples was tested. The results show that the particle size of siphon-refined CL-20 is about 800 nm~1 μm, which is more smooth, mellow, and dense...
Hindawi Publishing Corporation
Mon Mar 02, 2020 13:20
Simultaneous Determination of Synthetic Food Dyes Using a Single Cartridge for Preconcentration and Separation Followed by Photometric Detection
A novel preconcentration/separation method for simultaneous sorption-spectrophotometric determination of anionic food dyes Sunset Yellow and Tartrazine is proposed. The method is based on preconcentration of the dyes using solid phase extraction on a cartridge filled with silica chemically modified with C16 groups from aqueous solution at pH 1 followed by elution with water/acetonitrile mixture containing 2 mmol·L−1 KH2PO4 adjusted to pH 3 with a step gradient of acetonitrile content. This elution...
Hindawi Publishing Corporation
Mon Mar 02, 2020 13:20
Gastric Cancer in Young Adults: A Different Clinical Entity from Carcinogenesis to Prognosis
Approximately 5.0% of gastric cancer (GC) patients are diagnosed before the age of 40 and are not candidates for screening programs in most countries and regions. The incidence of gastric cancer in young adults (GCYA) has declined over time in most countries except in the United States. Genetic alterations, environmental factors, and lifestyle may predispose some young adults to GC. According to molecular classifications, the cancer of most GCYA patients belongs to the genomically stable or microsatellite...
Hindawi Publishing Corporation
Mon Mar 02, 2020 13:20
A Successful Pregnancy with Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a degenerative motor neurone disease that is rarely seen in the obstetric population. We present a 32-year-old patient who presented in her fourth pregnancy with a background history of ALS. There was complete involvement of the upper and lower motor neurone system and bulbar system without involvement of the sensory system. At 34 weeks of gestation, she had a full course of steroids and an elective caesarian section under general anaesthesia due to extreme...
Hindawi Publishing Corporation
Mon Mar 02, 2020 11:50
Oxidative Stress in Radiation-Induced Cardiotoxicity
There is a distinct increase in the risk of heart disease in people exposed to ionizing radiation (IR). Radiation-induced heart disease (RIHD) is one of the adverse side effects when people are exposed to ionizing radiation. IR may come from various forms, such as diagnostic imaging, radiotherapy for cancer treatment, nuclear disasters, and accidents. However, RIHD was mainly observed after radiotherapy for chest malignant tumors, especially left breast cancer. Radiation therapy (RT) has become one...
Hindawi Publishing Corporation
Mon Mar 02, 2020 11:35
Prevalence of Diabetes and Prediabetes among Children Aged 11-14 Years Old in Vietnam
Aim. Diabetes in children is becoming more prevalent in some countries. However, in most countries, little is known about the epidemiology of this disease. This study is aimed at estimating the prevalence of type 1 and type 2 diabetes and prediabetes among children in Vietnam and examining factors associated with the conditions. Methods. A total of 2880 students aged 11-14 years old were recruited for the survey, using a school-based and nationally representative sampling frame. Capillary blood samples...
Hindawi Publishing Corporation
Mon Mar 02, 2020 08:50
Dynamic Expression of HDAC3 in db/db Mouse RGCs and Its Relationship with Apoptosis and Autophagy
Background. Diabetic retinopathy (DR) is a severe complication of diabetes mellitus. DR is considered as a neurovascular disease. Retinal ganglion cell (RGC) loss plays an important role in the vision function disorder of diabetic patients. Histone deacetylase3 (HDAC3) is closely related to injury repair and nerve regeneration. The correlation between HDAC3 and retinal ganglion cells in diabetic retinopathy is still unclear yet. Methods. To investigate the chronological sequence of the abnormalities...
Hindawi Publishing Corporation
Mon Mar 02, 2020 08:50
Advanced Lung Adenocarcinoma Patient with ERBB2 Amplification Identified by Comprehensive Genomic Profiling Benefits from Trastuzumab
For non-small-cell lung cancer (NSCLC) patients without established actionable alterations in genes such as EGFR or ALK, options for targeted therapy remain limited in clinical practice. About 5% of lung adenocarcinoma patients have tumors with ERBB2 genetic alterations, with even fewer patients harboring ERBB2 amplification. Currently, clinical trials mainly use IHC, FISH, or mutation testing to identify potential responders to ERBB2-targeting agents. The use of next-generation sequencing (NGS)...
Hindawi Publishing Corporation
Mon Mar 02, 2020 08:50
Unusual Presentation of Bilateral Radiation-Induced Angiosarcoma of the Breast
Radiation-induced sarcoma of the breast is an iatrogenic malignancy that occurs secondary to radiotherapy, which is most commonly given following breast conservation surgery. It has an incidence of 3.2 per 1,000 patients at 15 years and is associated with a poor prognosis. We report a 62-year-old female with a history of bilateral breast conservation surgery and radiotherapy 5 years ago presenting with bilateral angiosarcoma. This case report highlights the importance of considering radiation-induced...
Hindawi Publishing Corporation
Mon Mar 02, 2020 08:50
Dexrazoxane Protects Cardiomyocyte from Doxorubicin-Induced Apoptosis by Modulating miR-17-5p
The usage of doxorubicin is hampered by its life-threatening cardiotoxicity in clinical practice. Dexrazoxane is the only cardioprotective medicine approved by the FDA for preventing doxorubicin-induced cardiac toxicity. Nevertheless, the mechanism of dexrazoxane is incompletely understood. The aim of our study is to investigate the possible molecular mechanism of dexrazoxane against doxorubicin-induced cardiotoxicity. We established a doxorubicin-induced mouse and cardiomyocyte injury model. Male...
Hindawi Publishing Corporation
Mon Mar 02, 2020 06:50
Fast Localization and Sectioning of Mouse Locus Coeruleus
The locus nucleus (LC) is a multifunctional nucleus which is also the source of norepinephrine in the brain. To date, there is no simple and easy method to locate the small LC in brain sectioning. Here we report a fast, accurate, and easy-to-follow protocol for the localization of mice LC in frozen sectioning. After fixation and dehydration, the intact brains of adult mice were placed on a horizontal surface and vertically cut along the posterior margin of the bilateral cerebral cortex. In the coronal...
Hindawi Publishing Corporation
Mon Mar 02, 2020 06:50
An Optimal Backoff Time-Based Internetwork Interference Mitigation Method in Wireless Body Area Network
When multiple Wireless Body Area Networks (WBANs) are aggregated, the overlapping region of their communications will result in internetwork interference, which could impose severe impacts on the reliability of WBAN performance. Therefore, how to mitigate the internetwork interference becomes the key problem to be solved urgently in practical applications of WBAN. However, most of the current researches on internetwork interference focus on traditional cellular networks and large-scale wireless sensor...
Hindawi Publishing Corporation
Mon Mar 02, 2020 06:05
The Association between Diabetes-Related Distress and Medication Adherence in Adult Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study
Background. Type 2 diabetes mellitus (T2DM) is a major public health problem associated with distress. T2DM can affect health outcomes and adherence to medications. Little is however known about the association between diabetes distress and medication adherence among patients with T2DM in Ghana. Objective. The objective of the present study is twofold: to estimate distress associated with T2DM and to examine its association with medication adherence. Methods. A hospital-based cross-sectional study...
Hindawi Publishing Corporation
Mon Mar 02, 2020 06:05

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