Abstract The aim of the present study was to investigate the knowledge about oral cancer in a Brazilian population, including initial clinical signs, causal factors, and the health professional of first choice when suspected of the disease. A total of 2261 participants were interviewed in a cross-sectional study, to investigate associations between sociodemographic descriptive variables and knowledge of oral cancer, risk factors, disease precursor lesions, and health professional...
Mon Mar 02, 2020 02:00
Abstract Lack of awareness of screening methods, risk factors, and symptoms may lead to late diagnosis and poor prognosis of cervical cancer. The plan of this study was to assess the level of awareness about cervical cancer and HPV vaccine among females of rural and urban areas of Haryana, India. This cross-sectional study was performed using a comprehensive self-designed questionnaire on 1500 women of urban (700) and rural (800) background aged 18–65 years, evaluating their knowledge...
Fri Feb 28, 2020 02:00
Abstract We aimed to investigate awareness of colorectal cancer (CRC) lifestyle risk factors, willingness to participate in CRC screening, and preferences concerning channels for information on CRC prevention in the general population, including the target age of the upcoming Norwegian national CRC screening program. The present study was a cross-sectional online survey of adults aged 39 to 55 years registered as Kantar Web Panel respondents in Norway. The survey included demographic...
Fri Feb 28, 2020 02:00
Abstract Triple‐negative breast cancer (TNBC) lacks a well‐defined molecular target and is associated with poorer outcomes compared to other breast cancer subtypes. Programmed cell death protein 1 (PD‐1)/programmed death‐ligand 1 (PD‐L1) blockade therapy shows a 10% to 20% response rate in TNBC patients. Our previous studies show that PD‐L1 proteins are heavily glycosylated in TNBC, and the glycosylation plays an important role in the PD‐L1 protein's stability and immunosuppressive function. However,...
Mon Mar 02, 2020 12:12
Abstract Background This study aimed to determine the optimal radiotherapy (RT) regimen for patients with clinical metastasis to the internal mammary lymph node (cIMN+) from breast cancer. Methods We retrospectively reviewed the medical records of 84 patients with cIMN+ breast cancer treated with curative surgery, taxane-based chemotherapy,...
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Abstract Background The aim of the present study was to evaluate MRI response rate and clinical outcome of short-course radiotherapy (SCRT) on rectal cancer as an alternative to chemoradiotherapy in patients where downstaging is indicated. Methods A retrospective analysis was performed of a patient cohort with rectal carcinoma (cT1-4cN0-2 cM0–1)...
Mon Mar 02, 2020 02:00
Abstract Background Three-dimensional Surface Imaging (3DSI) is a well-established method to objectively monitor morphological changes in the female breast in the field of plastic surgery. In contrast, in radiation oncology we are still missing effective tools, which can objectively and reproducibly assess and document adverse events in breast cancer radiotherapy within the framework of clinical studies. The aim of the present study...
Fri Feb 28, 2020 02:00
Zusammenfassung In den letzten Jahren ist aufgrund technischer Fortschritte mit einer Miniaturisierung der Systeme und Reduktion der postoperativen Komplikationen, Zunahme der Prävalenz der Herzinsuffizienz, dem Spendermangel im Bereich der Transplantation sowie steigender Lebenserwartung eine deutliche Zunahme der Patientenzahl mit permanenten Herzunterstützungssystemen zu verzeichnen. Dieses sehr spezielle Patientenkollektiv kann sowohl akute systemassoziierte Notfälle, wie z. B....
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Abstract Purpose The aim of this study was to compare tracheal intubation conditions after induction of anesthesia with a bolus of propofol-sufentanil or propofol-remifentanil and a rapid induction technique. Material and methods A total of 70 patients (American Society of Anesthesiologists (ASA) classification I‑II) undergoing outpatient surgery under general...
Fri Feb 28, 2020 02:00
The study was conducted with the aim to assess the psychometric measures of an adapted Arabic version of the Epworth Sleepiness Scale (ESS) among medical students at Sana’a University, Yemen. The cross-sectional study targeted 360 students (males: 176; females: 184) from the preclinical 3rd year (: 197) and the final clinical year (: 163). Participants self-filled an Arabic and slightly modified version of the 8-item Epworth Sleepiness Scale. Exploratory Principal Component Analysis (PCA) and Confirmatory...
Mon Mar 02, 2020 17:50
The fractional telegraph equation is a kind of important evolution equation, which has an important application in signal analysis such as transmission and propagation of electrical signals. However, it is difficult to obtain the corresponding analytical solution, so it is of great practical value to study the numerical solution. In this paper, the alternating segment pure explicit-implicit (PASE-I) and implicit-explicit (PASI-E) parallel difference schemes are constructed for time fractional telegraph...
Mon Mar 02, 2020 16:50
Endothelial cell damage caused by oxidative stress is widely considered to be a triggering event in atherosclerosis (AS). However, the specific effect elicited by autophagy in endothelial cells undergoing oxidative stress remains controversial, especially during end-stage autophagy. The inhibition of end-stage autophagy has been reported to increase cell pyroptosis and contribute to endothelial damage. Several studies have shown that microRNA-103 is involved in end-stage autophagy; however, its specific...
Mon Mar 02, 2020 16:50
Inflammation and oxidative stress play key roles in the process of aging and age-related diseases. Since serine availability plays important roles in the support of antioxidant and anti-inflammatory defense system, we explored whether serine deficiency affects inflammatory and oxidative status in D-galactose-induced aging mice. Male mice were randomly assigned into four groups: mice fed a basal diet, mice fed a serine- and glycine-deficient (SGD) diet, mice injected with D-galactose and fed a basal...
Mon Mar 02, 2020 16:35
Carbon nanotubes were synthesized by using a nanostructured conducting polymer—the polypyrrole nanofiber via microwave radiation. The radiation time was set to be 30, 60, and 90 seconds, respectively. The morphological evolvements of the as-synthesized carbon nanotubes with increased radiation time (e.g., shape, diameter, wall structure, and catalyst size) were carefully investigated, and the possible growth mode was discussed in detail. It was found that the growth mode of the carbon nanotubes synthesized...
Mon Mar 02, 2020 14:50
Background and Aims. Endoscopic submucosal dissection (ESD) is widely performed for early gastric cancer (EGC). We have sometimes encountered gastric cancer lesions for which ESD was performed and at which pathologically advanced cancer was found. In this study, we performed clinicopathological examination of lesions whose endoscopic diagnosis and pathology differed substantially. Methods. ESD was performed for 2,194 gastric cancer lesions (1,753 cases) in our institute from April 2005 through March...
Mon Mar 02, 2020 14:20
Ocular involvement with disseminated coccidiodal infection is rare. Even rarer is a patient presenting with symptomatic chorioretinitis first, followed weeks later by systemic symptoms of disseminated coccidioidomycosis. This highlights the need for physicians to have a heightened suspicion for testing for valley fever in patients living in endemic regions who present with ocular inflammation so that rapid and timely initiation of antifungal therapy may prevent loss of vision.
Mon Mar 02, 2020 14:20
Moxibustion is a thermal therapy in traditional Chinese medicine that relies on the heat from burning moxa to be transferred beneath the skin surface. Although moxibustion has long been in widespread practice, the mechanism of heat transfer modality and temperature distribution during this treatment is not yet well understood. The current paper presents the first examination by magnetic resonance imaging (MRI) of the three-dimensional temperature elevation during moxibustion treatment. A mathematical...
Mon Mar 02, 2020 13:50
Objective. Early nutritional support in patients with gastric cancer can improve their nutritional status, but the impact on immune function has not been confirmed. This study aimed to analyze the effects of Qihuang decoction combined with enteral nutrition on nutrition and the immune function of postoperative gastric cancer. Methods. 120 patients with postoperative gastric cancer in the study group and 117 in the control group were selected as the study subjects from our hospital at random. Indications...
Mon Mar 02, 2020 13:50
A real form of a complex semisimple Lie group G has only finitely many orbits in any given compact G-homogeneous projective algebraic manifold . A maximal compact subgroup of has special orbits C which are complex submanifolds in the open orbits of . These special orbits C are characterized as the closed orbits in Z of the complexification K of . These are referred to as cycles. The cycles intersect Schubert varieties S transversely at finitely many points. Describing these points and their multiplicities...
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