Abstract Adipose‐derived stem cells (ASCs) possess strong regenerative potencies and have been used to improve wound healing in animal models and clinical studies. However, the use of ASCs on scarless wound healing is not satisfactory. Matrix metalloproteinase 3 (MMP‐3) is involved in extracellular matrix (ECM) remolding and scar formation. We aimed to investigate the effect of ASCs stable expressing MMP‐3 (ASCs‐MMP‐3) on wound healing and scarring. A cutaneous wound healing animal model was used...
Fri Jul 31, 2020 18:53
Abstract Isotretinoin is prescribed in many dermatologic disorders, but mostly in acne. There is limited research about oxidative stress induced by isotretinoin and its effects on the liver tissue, muscle tissue, and blood. In this study, oxidative damage of isotretinoin on the liver, muscles, and blood in rats at the therapeutic dosage for humans, is evaluated. Thirty, 2‐months‐old Wistar albino rats were randomly divided into 4 groups. Isotretinoin was administered at the human equivalent low...
Fri Jul 31, 2020 18:41
Fri Jul 31, 2020 12:03
Abstract Many traditional Chinese medicine compositions can moisturize the skin and utilize in cosmetics. Using a combination of Chinese Medicine Materials and guided by Traditional Chinese Medicine principles, this study selected Echinacea purpurea to protect the skin barrier, Dendrobium nobile to clear heat and promote fluid production, Sophora flavescens to clear heat for diminished inflammation, and Aloe vera combined Lycium barbarum to nourish yin, to together form a "poly TCM moisturizing...
Fri Jul 31, 2020 11:59
Abstract Melanoma is the most severe form of skin cancer and its incidence has increased over the past few decades. COVID‐19 pandemic affected the diagnosis and management of many diseases including melanoma. In this study, we aimed to provide a review focused on the diagnosis and management of melanoma in the era of COVID‐19. A comprehensive search was conducted on PubMed, Web of Science, and Google Scholar databases using the keywords "melanoma,”, "coronavirus", "COVID 19" and "SARS‐CoV‐2". The...
Fri Jul 31, 2020 11:45
Abstract Psoriasis patients are at increased risk of atherosclerosis, characterized by endothelial dysfunction, linked through systemic inflammation. Anti‐TNF‐a therapy seems to decrease this risk. The purpose of this study was to measure the levels of serum markers associated with systemic inflammation in psoriasis patients, compared to healthy individuals and to investigate the change in their levels after 3 months and 2 years of adalimumab therapy. We investigated 4 biomarkers: high‐sensitivity...
Thu Jul 30, 2020 21:19
Abstract Cutaneous leishmaniasis (CL) is endemic in Iraq. After the last war in Iraq against Islamic State in Iraq and Syria (ISIS), the number of CL cases has peaked particularly in children. International guidelines do not provide an insight on how to choose treatment regimen of CL in children. The aim of this paper was to study the efficacy of intralesional sodium stibogluconate (SSG) therapy for school age children with CL. In the period between June 2016 and June 2019, 288 internally displaced...
Thu Jul 30, 2020 20:29
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