Abstract Background low dose oral minoxidil (OM) is an increasingly used treatment for androgenetic alopecia and other types of hair loss. Objectives to analyze available data of patients treated with OM, focusing on safety and adverse effects. Methods a search in PubMed and EMBASE was performed for studies reporting the treatment of alopecia with OM. Individual patient data available for pooled‐analysis were sex, dose of OM, presence of hypertrichosis and lower limb edema. Results...
Wed Aug 05, 2020 20:39
Abstract Children with epidermolysis bullosa (EB) experienced the highest quality of life impact among several skin conditions and have problems which had not been reported by parents of children with other skin diseases. The EB‐specific module of the Infants and Toddlers Dermatology Quality of Life (InToDermQoL) questionnaire was recently developed to measure the impact of disease‐specific aspects in children from birth to the age of four years. The aim of this study was initial validation of the...
Wed Aug 05, 2020 19:59
Abstract The current systematic review aimed to evaluate the efficacy and safety of dabrafenib plus trametinib (dabrafenib‐trametinib) with those of other therapeutic alternatives in the treatment of patients with BRAF V600 mutation unresectable or metastatic melanoma. The search was carried out on four databases up to July‐2018. Two separate network meta‐analyses (NMA) were performed using the frequentist method (random effects): one with an exclusive population with BRAF V600 mutation (NMA‐pBRAFV600)...
Wed Aug 05, 2020 19:04
ABSTRACT Introduction Off‐label treatment with reduced doses of biological therapies for moderate‐severe psoriasis is used, but its efficacy, safety and persistence are not well known. Objectives We have compared reduced doses with standard an escalated doses and study predictive factors for a successful reduction of doses lasting more than 6 months. Results We included 303 subcutaneous treatments (33% with reduced doses and 29% with escalated doses). Eighty (80.8%) reduced treatments...
Wed Aug 05, 2020 18:48
Abstract Background Traditional medicinal systems are widely practiced in the Indian subcontinent for a wide variety of diseases. We aimed to identify the various home remedies used by people to treat numerous pediatric dermatoses. Material and Methods It was an observational study carried out over 18 months in which 150 children attending our clinics were recruited. A detailed history regarding the various indigenous preparations used was taken from caregivers and noted in a proforma....
Wed Aug 05, 2020 18:38
Abstract Objective Platelet‐rich plasma (PRP) may be effective for treating androgenetic alopecia (AGA); albeit, its efficacy in men and women is still debated. We conducted meta‐analyses to determine PRP efficacy in men and women separately. Methods Studies were identified after systematically searching for trials that investigated PRP monotherapy for AGA in men and women separately. We included trials that studied PRP injections on hair density and/or hair diameter. Pooled effect of PRP...
Wed Aug 05, 2020 18:28
Abstract Up until now, real‐life experiences on the efficacy of risankizumab in patients who had previously failed anti‐IL17, anti‐IL12/23 or anti‐IL23 inhibitor are not reported. We carried out a single‐centre, retrospective study, to evaluate the efficacy, safety and tolerability of patients under risankizumab who previously failed anti‐IL17, anti‐IL12/23 or anti‐IL23 inhibitors in a real‐life setting. A total of 8 patients were enrolled (4 men and 4 women, mean age 45.8 ± 14.3 years). Five of...
Wed Aug 05, 2020 18:24
ABSTRACT Background Hypertrophic scar is a disease with complicated treatment methods. Although there are numerous studies in the literature definitive therapy has not been reported yet. Objective In this study, we aimed to evaluate the short and long‐ term effects of HBOT on hypertrophic scar formation in a rabbit ear model. Material and Methods A total of 20 male New Zealand rabbits weighing 2.1‐ 2.4 kg were used in this study. The rabbits in group 2 were exposed to hyperbaric oxygen...
Wed Aug 05, 2020 18:15
Abstract Background/Objectives Several recent studies have reported a considerably higher overall survival rate in females in various geographic regions This study further investigates the characteristics of melanoma that contribute to overall survival of women residing in the United States. Methods Chi‐Square, Kaplan‐Meier, and Cox regression models were used to analyze differences in demographics, treatment, and survival of invasive cutaneous melanoma in men and women diagnosed from 2004...
Wed Aug 05, 2020 14:34
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