JCM, Vol. 9, Pages 2544: Telomeres, DNA Damage and Ageing: Potential Leads from Ayurvedic Rasayana (Anti-Ageing) Drugs Journal of Clinical Medicine doi: 10.3390/jcm9082544 Authors: Sharma Martins Ageing, while a relentless, unidirectional and pleiotropic phenomenon of life, is a key trigger for several age-related disorders, such as cancer, cataract, osteoporosis, hypertension, cardiovascular (CV), metabolic and even neurodegenerative ailments, including Alzheimer’s (AD)...
Thu Aug 06, 2020 03:00
JCM, Vol. 9, Pages 2543: Clinical and Imaging Characteristics in Patients with SARS-CoV-2 Infection and Acute Intracranial Hemorrhage Journal of Clinical Medicine doi: 10.3390/jcm9082543 Authors: Jawed Nawabi Andrea Morotti Moritz Wildgruber Gregoire Boulouis Hermann Kraehling Frieder Schlunk Elif Can Helge Kniep Götz Thomalla Marios Psychogios Bernd Hamm Jens Fiehler Uta Hanning Peter Sporns Background and Purpose: Intracranial hemorrhage has been...
Thu Aug 06, 2020 03:00
JCM, Vol. 9, Pages 2542: Second Update for Anaesthetists on Clinical Features of COVID-19 Patients and Relevant Management Journal of Clinical Medicine doi: 10.3390/jcm9082542 Authors: Weenink Preckel Hulst Hermanides de Jong Schlack Stevens Sperna Weiland Hollmann The COVID-19 pandemic poses great challenges for healthcare workers around the world, including perioperative specialists. Previously, we provided a first overview of available literature on...
Thu Aug 06, 2020 03:00
JCM, Vol. 9, Pages 2545: Clinical and Radiologic Outcomes of Combined Use of Biocomposite and PEEK Suture Anchors during Arthroscopic Rotator Cuff Repair: A Prospective Observational Study Journal of Clinical Medicine doi: 10.3390/jcm9082545 Authors: Lee Lee The aim of the current study was to evaluate the functional and radiologic outcomes of biocompatible non-absorbable PEEK (polyetheretherketone) and biocomposite (poly-L-lactic acid/poly(lactic-co-glycolic acid) 70% + β-tricalcium...
Thu Aug 06, 2020 03:00
JCM, Vol. 9, Pages 2537: Deep Learning-Based Segmentation and Quantification of Retinal Capillary Non-Perfusion on Ultra-Wide-Field Retinal Fluorescein Angiography Journal of Clinical Medicine doi: 10.3390/jcm9082537 Authors: Joan M. Nunez do Rio Piyali Sen Rajna Rasheed Akanksha Bagchi Luke Nicholson Adam M. Dubis Christos Bergeles Sobha Sivaprasad Reliable outcome measures are required for clinical trials investigating novel agents for preventing progression of...
Thu Aug 06, 2020 03:00
JCM, Vol. 9, Pages 2541: General Overview of Nontuberculous Mycobacteria Opportunistic Pathogens: Mycobacterium avium and Mycobacterium abscessus Journal of Clinical Medicine doi: 10.3390/jcm9082541 Authors: Kimberly To Ruoqiong Cao Aram Yegiazaryan James Owens Vishwanath Venketaraman Nontuberculous mycobacteria (NTM) are emerging human pathogens, causing a wide range of clinical diseases affecting individuals who are immunocompromised and who have underlying health conditions....
Thu Aug 06, 2020 03:00
JCM, Vol. 9, Pages 2540: Athlete’s Passport: Prevention of Infections, Inflammations, Injuries and Cardiovascular Diseases Journal of Clinical Medicine doi: 10.3390/jcm9082540 Authors: Cristina Mennitti Mariarita Brancaccio Luca Gentile Annaluisa Ranieri Daniela Terracciano Michele Cennamo Evelina La Civita Antonietta Liotti Giovanni D’Alicandro Cristina Mazzaccara Giulia Frisso Raffaela Pero Barbara Lombardo Olga Scudiero Laboratory medicine in...
Thu Aug 06, 2020 03:00
JCM, Vol. 9, Pages 2538: Diagnostic and Prognostic Value of Conventional Brain MRI in the Clinical Work-Up of Patients with Amyotrophic Lateral Sclerosis Journal of Clinical Medicine doi: 10.3390/jcm9082538 Authors: Giovanni Rizzo Anna Marliani Stella Battaglia Luca Albini Riccioli Silvia De Pasqua Veria Vacchiano Rossella Infante Patrizia Avoni Vincenzo Donadio Massimiliano Passaretti Ilaria Bartolomei Fabrizio Salvi Rocco Liguori on behalf of the BoReALS...
Thu Aug 06, 2020 03:00
JCM, Vol. 9, Pages 2539: Impact of Axial Eye Size on Retinal Microvasculature Density in the Macular Region Journal of Clinical Medicine doi: 10.3390/jcm9082539 Authors: M. Hafi Khan Andrew K. C. Lam James A. Armitage Lisa Hanna Chi-ho To Alex Gentle Mechanical tissue stresses are important contributors to the increased risk of sight-threatening pathology in larger, more myopic eyes. The contribution of altered ocular vasculature to the development of this pathology is...
Thu Aug 06, 2020 03:00
JCM, Vol. 9, Pages 2536: Investigation of the PD-1 and PD-L1 Immune Checkpoint Molecules Throughout Healthy Human Pregnancy and in Nonpregnant Women Journal of Clinical Medicine doi: 10.3390/jcm9082536 Authors: Matyas Meggyes David U. Nagy Laszlo Szereday Background: A growing body of evidence supports the importance of PD-1 and PD-L1, especially in the materno-fetal interface, although limited information is available about the peripheral expression of these molecules during the...
Thu Aug 06, 2020 03:00
JFMK, Vol. 5, Pages 61: Comparison of Mandibular Arch Expansion by the Schwartz Appliance Using Two Activation Protocols: A Preliminary Retrospective Clinical Study Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5030061 Authors: Vincenzo Quinzi Stefano Mummolo Francesca Bertolazzi Vincenzo Campanella Giuseppe Marzo Enrico Marchetti Background and objectives: Dental crowding is more pronounced in the mandible than in the maxilla. When exceeding a significant...
Thu Aug 06, 2020 03:00
JoF, Vol. 6, Pages 128: Natural Products from Endophytic Fungi Associated with Rubiaceae Species Journal of Fungi doi: 10.3390/jof6030128 Authors: Jacqueline Santos Cruz Carla Amaral da Silva Lidilhone Hamerski This review presents the chemical diversity and pharmacological properties of secondary metabolites produced by endophytic fungi associated with various genera of Rubiaceae. Several classes of natural products are described for these endophytes, although, this study highlights...
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JoF, Vol. 6, Pages 127: Blue Light Induced Edible Mushroom (Lentinula edodes) Proteomic Analysis Journal of Fungi doi: 10.3390/jof6030127 Authors: Youn Jin Park Myoung Jun Jang Blue light is an important environmental factor that induces mushroom growth and morphological changes. In this study, after confirming the morphological difference between Lentinula edodes (LE) under blue light condition (BL) and lightless condition (LL), the increase and decrease in LE protein and the expression...
Thu Aug 06, 2020 03:00
Life, Vol. 10, Pages 142: Does the Introduction of Alien Species Represent a Sanitary Threat for Native Species? The Case of the Eastern Cottontail Sylvilagus floridanus in Italy Life doi: 10.3390/life10080142 Authors: Tizzani Andrade Min Peano Meneguz Introduction of alien species is a well-known threat to biodiversity. Where newly introduced, alien species may pose a risk for the local ecological community by competing for resources or by introducing pathogens. Sylvilagus...
Thu Aug 06, 2020 03:00
Life, Vol. 10, Pages 141: Evaluation of GammaH2AX in Buccal Cells as a Molecular Biomarker of DNA Damage in Alzheimer’s Disease in the AIBL Study of Ageing Life doi: 10.3390/life10080141 Authors: Mohammad Sabbir Siddiqui Maxime Francois Stephanie Rainey-Smith Ralph Martins Colin L. Masters David Ames Christopher C. Rowe Lance S. Macaulay Michael F. Fenech Wayne R. Leifert In response to double-stranded breaks (DSBs) in chromosomal DNA, H2AX (a member of histone...
Thu Aug 06, 2020 03:00
Life, Vol. 10, Pages 140: Seaweed’s Bioactive Candidate Compounds to Food Industry and Global Food Security Life doi: 10.3390/life10080140 Authors: Adriana Leandro Diana Pacheco João Cotas João C. Marques Leonel Pereira Ana M. M. Gonçalves The world population is continuously growing, so it is important to keep producing food in a sustainable way, especially in a way that is nutritious and in a sufficient quantity to overcome global needs. Seaweed grows, and can be cultivated,...
Thu Aug 06, 2020 03:00
Medical Sciences, Vol. 8, Pages 31: Short-Term Effects of Air Pollution on Coronary Events in Strasbourg, France—Importance of Seasonal Variations Medical Sciences doi: 10.3390/medsci8030031 Authors: Baptiste Vaudrey Marie Mielcarek Erik Sauleau Nicolas Meyer Benjamin Marchandot Marie Moitry Pierre Robellet Thierry Reeb Laurence Jesel Patrick Ohlmann Thomas Bourdrel Olivier Morel The aim of this study, is to investigate the effects of a short-term exposure...
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Metabolites, Vol. 10, Pages 320: Promoter Architecture and Promoter Engineering in Saccharomyces cerevisiae Metabolites doi: 10.3390/metabo10080320 Authors: Hongting Tang Yanling Wu Jiliang Deng Nanzhu Chen Zhaohui Zheng Yongjun Wei Xiaozhou Luo Jay D. Keasling Promoters play an essential role in the regulation of gene expression for fine-tuning genetic circuits and metabolic pathways in Saccharomyces cerevisiae (S. cerevisiae). However, native promoters in S. cerevisiae...
Thu Aug 06, 2020 03:00
Metabolites, Vol. 10, Pages 319: A Multilevel Bayesian Approach to Improve Effect Size Estimation in Regression Modeling of Metabolomics Data Utilizing Imputation with Uncertainty Metabolites doi: 10.3390/metabo10080319 Authors: Christopher E. Gillies Theodore S. Jennaro Michael A. Puskarich Ruchi Sharma Kevin R. Ward Xudong Fan Alan E. Jones Kathleen A. Stringer To ensure scientific reproducibility of metabolomics data, alternative statistical methods are needed....
Thu Aug 06, 2020 03:00
Metabolites, Vol. 10, Pages 318: Metabolic Profiles of Whole, Parotid and Submandibular/Sublingual Saliva Metabolites doi: 10.3390/metabo10080318 Authors: Marco Meleti Eleonora Quartieri Rita Antonelli Margherita E. Pezzi Benedetta Ghezzi Maria Vittoria Viani Giacomo Setti Emanuela Casali Elena Ferrari Tecla Ciociola Alberto Spisni Thelma A. Pertinhez The detection of salivary molecules associated with pathological and physiological alterations has encouraged...
Thu Aug 06, 2020 03:00
Microorganisms, Vol. 8, Pages 1196: Gastric Microbiome Diversities in Gastric Cancer Patients from Europe and Asia Mimic the Human Population Structure and Are Partly Driven by Microbiome Quantitative Trait Loci Microorganisms doi: 10.3390/microorganisms8081196 Authors: Bruno Cavadas Rui Camacho Joana C. Ferreira Rui M. Ferreira Ceu Figueiredo Alvis Brazma Nuno A. Fonseca Luísa Pereira The human gastrointestinal tract harbors approximately 100 trillion microorganisms...
Thu Aug 06, 2020 03:00
Microorganisms, Vol. 8, Pages 1198: Spoilage of Chilled Fresh Meat Products during Storage: A Quantitative Analysis of Literature Data Microorganisms doi: 10.3390/microorganisms8081198 Authors: Ngoc-Du Martin Luong Louis Coroller Monique Zagorec Jeanne-Marie Membré Sandrine Guillou A literature search was performed on spoilage of fresh meat products by combining keyword query, text mining and expert elicitation. From the 258 collected studies, a quantitative analysis was...
Thu Aug 06, 2020 03:00
Microorganisms, Vol. 8, Pages 1197: Citrus Psorosis Virus: Current Insights on a Still Poorly Understood Ophiovirus Microorganisms doi: 10.3390/microorganisms8081197 Authors: Zineb Belabess Tourya Sagouti Naima Rhallabi Abdessalem Tahiri Sébastien Massart Rachid Tahzima Rachid Lahlali M. Haissam Jijakli Citrus psorosis was reported for the first time in Florida in 1896 and was confirmed as a graft-transmissible disease in 1934. Citrus psorosis virus (CPsV) is the...
Thu Aug 06, 2020 03:00
Microorganisms, Vol. 8, Pages 1195: Genetic Impairment of Cellulose Biosynthesis Increases Cell Wall Fragility and Improves Lipid Extractability from Oleaginous Alga Nannochloropsis salina Microorganisms doi: 10.3390/microorganisms8081195 Authors: Seok Won Jeong Kwon HwangBo Jong Min Lim Seung Won Nam Bong Soo Lee Byeong-ryool Jeong Yong Keun Chang Won-Joong Jeong Youn-Il Park In microalgae, photosynthesis provides energy and sugar phosphates for the biosynthesis...
Thu Aug 06, 2020 03:00
Microorganisms, Vol. 8, Pages 1194: Generation of a Non-Transgenic Genetically Improved Yeast Strain for Wine Production from Nitrogen-Deficient Musts Microorganisms doi: 10.3390/microorganisms8081194 Authors: Eduardo Kessi-Pérez Jennifer Molinet Verónica García Omayra Aguilera Fernanda Cepeda María López Santiago Sari Raúl Cuello Iván Ciklic María Rojo Mariana Combina Cristián Araneda Claudio Martínez The yeast Saccharomyces cerevisiae is the main...
Thu Aug 06, 2020 03:00
Microorganisms, Vol. 8, Pages 1199: Lactic Acid Bacteria Adjunct Cultures Exert a Mitigation Effect against Spoilage Microbiota in Fresh Cheese Microorganisms doi: 10.3390/microorganisms8081199 Authors: Daniela Bassi Simona Gazzola Eleonora Sattin Fabio Dal Bello Barbara Simionati Pier Sandro Cocconcelli Lactic acid bacteria (LAB) have a strong mitigation potential as adjunct cultures to inhibit undesirable bacteria in fermented foods. In fresh cheese with low salt concentration,...
Thu Aug 06, 2020 03:00
Molecules, Vol. 25, Pages 3588: Mineral Composition of Three Popular Wild Mushrooms from Poland Molecules doi: 10.3390/molecules25163588 Authors: Michalina Gałgowska Renata Pietrzak-Fiećko The region of Warmia and Mazury is characterized by the special diversity and richness of its natural environment, including large forest complexes, where wild mushrooms are commonly collected and consumed. This study aimed to examine the differences in mineral content (calcium, magnesium, sodium,...
Thu Aug 06, 2020 03:00
Molecules, Vol. 25, Pages 3587: Unravelling the Miscibility of Poly(2-oxazoline)s: A Novel Polymer Class for the Formulation of Amorphous Solid Dispersions Molecules doi: 10.3390/molecules25163587 Authors: Melissa Everaerts Ali Tigrine Victor R. de la Rosa Richard Hoogenboom Peter Adriaensens Christian Clasen Guy Van den Mooter Water-soluble polymers are still the most popular carrier for the preparation of amorphous solid dispersions (ASDs). The advantage of this type...
Thu Aug 06, 2020 03:00
Molecules, Vol. 25, Pages 3585: Water-Extracted Ganoderma lucidum Induces Apoptosis and S-Phase Arrest via Cyclin-CDK2 Pathway in Glioblastoma Cells Molecules doi: 10.3390/molecules25163585 Authors: An-Yi Cheng Yi-Chung Chien Han-Chung Lee Yi-Hsien Hsieh Yung-Luen Yu Glioblastoma is one of the most common and most aggressive brain cancers. The current treatment is mainly surgery, chemotherapy, and radiation therapy, but the results are not satisfactory. Ganoderma lucidum...
Thu Aug 06, 2020 03:00
Molecules, Vol. 25, Pages 3586: Synthesis of 2,4,6-Trinitrotoluene (TNT) Using Flow Chemistry Molecules doi: 10.3390/molecules25163586 Authors: Dimitris Kyprianou Michael Berglund Giovanni Emma Grzegorz Rarata David Anderson Gabriela Diaconu Vassiliki Exarchou This paper describes the nitration of 2,4-dinitrotoluene (DNT) and its conversion to 2,4,6-trinitrotoluene (TNT) at a gram scale with the use of a fully automated flow chemistry system. The conversion of DNT to...
Thu Aug 06, 2020 03:00
Molecules, Vol. 25, Pages 3583: A Leopard Cannot Change Its Spots: Unexpected Products from the Vilsmeier Reaction on 5,10,15-Tritolylcorrole Molecules doi: 10.3390/molecules25163583 Authors: Fabrizio Caroleo Greta Petrella Lorena Di Zazzo Sara Nardis Beatrice Berionni Berna Daniel O. Cicero Roberto Paolesse The reaction of 5,10,15-tritolylcorrole with 3-dimethylaminoacrolein (3-DMA) and POCl3 gives a further example of the rebel reactivity of this contracted macrocycle....
Thu Aug 06, 2020 03:00
Molecules, Vol. 25, Pages 3584: Synthesis, Crystal Structures and Anticancer Studies of Morpholinyldithiocarbamato Cu(II) and Zn(II) Complexes Molecules doi: 10.3390/molecules25163584 Authors: Peter A. Ajibade Fartisincha P. Andrew Nandipha L. Botha Nolwazi Solomane Cu(II) and Zn(II) morpholinyldithiocarbamato complexes, formulated as [Cu(MphDTC)2] and [Zn(μ-MphDTC)2(MphDTC)2], where MphDTC is morpholinyldithiocarbamate were synthesized and characterized by elemental...
Thu Aug 06, 2020 03:00
Molecules, Vol. 25, Pages 3581: Asoprisnil, a Selective Progesterone Receptor Modulator (SPRM), Inhibits Melanosome Export in B16F10 Cells and HEMn-DP Melanocytes Molecules doi: 10.3390/molecules25163581 Authors: Shilpi Goenka Sanford R. Simon Previous studies have reported that estrogen hormone promotes melanogenesis while progesterone inhibits it. A selective estrogen receptor modulator (SERM), tamoxifen, has been shown to promote melanogenesis; however, to date, there have been...
Thu Aug 06, 2020 03:00
Molecules, Vol. 25, Pages 3580: Chinese Yellow Rice Wine Processing with Reduced Ethyl Carbamate Formation by Deleting Transcriptional Regulator Dal80p in Saccharomyces cerevisiae Molecules doi: 10.3390/molecules25163580 Authors: Tianyu Wei Zhihua Jiao Jingjin Hu Hanghang Lou Qihe Chen Ethyl carbamate (EC) is a potential carcinogen that forms spontaneously during Chinese rice wine fermentation. The primary precursor for EC formation is urea, which originates from both external...
Thu Aug 06, 2020 03:00
Molecules, Vol. 25, Pages 3582: Assessment of Protein Content and Phosphorylation Level in Synechocystis sp. PCC 6803 under Various Growth Conditions Using Quantitative Phosphoproteomic Analysis Molecules doi: 10.3390/molecules25163582 Authors: Masakazu Toyoshima Yuma Tokumaru Fumio Matsuda Hiroshi Shimizu The photosynthetic apparatus and metabolic enzymes of cyanobacteria are subject to various controls, such as transcriptional regulation and post-translational modifications,...
Thu Aug 06, 2020 03:00
Molecules, Vol. 25, Pages 3578: Experimental Pretreatment with Chlorogenic Acid Prevents Transient Ischemia-Induced Cognitive Decline and Neuronal Damage in the Hippocampus through Anti-Oxidative and Anti-Inflammatory Effects Molecules doi: 10.3390/molecules25163578 Authors: Tae-Kyeong Lee Il-Jun Kang Bora Kim Hye Jin Sim Dae- Won Kim Ji Hyeon Ahn Jae-Chul Lee Sungwoo Ryoo Myoung Cheol Shin Jun Hwi Cho Young-Myeong Kim Joon Ha Park Soo Young Choi Moo-Ho...
Thu Aug 06, 2020 03:00
Molecules, Vol. 25, Pages 3579: Novel Methodologies for Chemical Activation in Organic Synthesis under Solvent-Free Reaction Conditions Molecules doi: 10.3390/molecules25163579 Authors: Claudia Gabriela Avila-Ortiz Eusebio Juaristi One central challenge for XXI century chemists is the development of sustainable processes that do not represent a risk either to humanity or to the environment. In this regard, the search for more efficient and clean alternatives to achieve the chemical...
Thu Aug 06, 2020 03:00
Molecules, Vol. 25, Pages 3577: Synthesis and Evaluation of Antimicrobial and Cytotoxic Activity of Oxathiine-Fused Quinone-Thioglucoside Conjugates of Substituted 1,4-Naphthoquinones Molecules doi: 10.3390/molecules25163577 Authors: Yuri E. Sabutski Ekaterina S. Menchinskaya Ludmila S. Shevchenko Ekaterina A. Chingizova Artur R. Chingizov Roman S. Popov Vladimir A. Denisenko Valery V. Mikhailov Dmitry L. Aminin Sergey G. Polonik A series of new tetracyclic...
Thu Aug 06, 2020 03:00
Molecules, Vol. 25, Pages 3576: 1,4-Disubstituted 1,2,3-Triazoles as Amide Bond Surrogates for the Stabilisation of Linear Peptides with Biological Activity Molecules doi: 10.3390/molecules25163576 Authors: Lisa-Maria Rečnik Wolfgang Kandioller Thomas L. Mindt Peptides represent an important class of biologically active molecules with high potential for the development of diagnostic and therapeutic agents due to their structural diversity, favourable pharmacokinetic properties,...
Thu Aug 06, 2020 03:00
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