Antibiotics, Vol. 9, Pages 487: Potent Antibacterial Prenylated Acetophenones from the Australian Endemic Plant Acronychia crassipetala Antibiotics doi: 10.3390/antibiotics9080487 Authors: Tran Olsson McMillan Cullen Parsons Reddell Ogbourne Acronychia crassipetala is an endemic plant species in Australia. Its phytochemistry and therapeutic properties are underexplored. The hexane extract of the fruit A. crassipetala T. G. Hartley was found to inhibit the growth...
Thu Aug 06, 2020 03:00
Antibiotics, Vol. 9, Pages 488: Synthesis of Degraded Limonoid Analogs as New Antibacterial Scaffolds against Staphylococcus aureus Antibiotics doi: 10.3390/antibiotics9080488 Authors: Ferrera-Suanzes Prieto Medina-Olivera Botubol-Ares Galán-Sánchez Rodríguez-Iglesias Hernández-Galán Durán-Peña Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) have become serious infections in humans and ruminants. S. aureus strains are showing...
Thu Aug 06, 2020 03:00
Antibiotics, Vol. 9, Pages 484: In the Age of Synthetic Biology, Will Antimicrobial Peptides be the Next Generation of Antibiotics? Antibiotics doi: 10.3390/antibiotics9080484 Authors: Félix Jaumaux Luz P. Gómez de Cadiñanos Philippe Gabant Antibiotics have changed human health and revolutionised medical practice since the Second World War. Today, the use of antibiotics is increasingly limited by the rise of antimicrobial-resistant strains. Additionally, broad-spectrum antibiotic...
Thu Aug 06, 2020 03:00
Antibiotics, Vol. 9, Pages 485: Impact of Colistin Dosing on the Incidence of Nephrotoxicity in a Tertiary Care Hospital in Saudi Arabia Antibiotics doi: 10.3390/antibiotics9080485 Authors: Reem Almutairy Waad Aljrarri Afnan Noor Pansy Elsamadisi Nour Shamas Mohammad Qureshi Sherine Ismail Colistin therapy is associated with the development of nephrotoxicity. We examined the incidence and risk factors of nephrotoxicity associated with colistin dosing. We included adult...
Thu Aug 06, 2020 03:00
Antibiotics, Vol. 9, Pages 486: Update on Acute Bone and Joint Infections in Paediatrics: A Narrative Review on the Most Recent Evidence-Based Recommendations and Appropriate Antinfective Therapy Antibiotics doi: 10.3390/antibiotics9080486 Authors: Giovanni Autore Luca Bernardi Susanna Esposito Acute bone and joint infections (BJIs) in children may clinically occur as osteomyelitis (OM) or septic arthritis (SA). In clinical practice, one-third of cases present a combination of...
Thu Aug 06, 2020 03:00
Antioxidants, Vol. 9, Pages 714: Antioxidant Potential of Psychotropic Drugs: From Clinical Evidence to In Vitro and In Vivo Assessment and toward a New Challenge for in Silico Molecular Design Antioxidants doi: 10.3390/antiox9080714 Authors: Ribaudo Bortoli Pavan Zagotto Orian Due to high oxygen consumption, the brain is particularly vulnerable to oxidative stress, which is considered an important element in the etiopathogenesis of several mental disorders, including...
Thu Aug 06, 2020 03:00
Antioxidants, Vol. 9, Pages 713: Cytoprotective Activity of Natural and Synthetic Antioxidants Antioxidants doi: 10.3390/antiox9080713 Authors: Kateřina Valentová Numerous chronic diseases including cancer, cardiovascular, chronic respiratory or neurodegenerative diseases, diabetes mellitus, retinal damage, and others are associated with oxidative stress [...]
Thu Aug 06, 2020 03:00
Atmosphere, Vol. 11, Pages 831: Cold and Dense Plasma Sheet Caused by Solar Wind Entry: Direct Evidence Atmosphere doi: 10.3390/atmos11080831 Authors: Yue Yu Zuzheng Chen Fang Chen We present a coordinated observation with the Magnetospheric Multiscale (MMS) mission, located in the Earth’s magnetotail plasma sheet, and the Acceleration, Reconnection, Turbulence, and Electrodynamics of the Moon’s Interaction with the Sun (ARTEMIS) mission, located in the solar...
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Atmosphere, Vol. 11, Pages 830: Assessment of Soybean Evapotranspiration and Controlled Water Stress Using Traditional and Converted Evapotranspirometers Atmosphere doi: 10.3390/atmos11080830 Authors: Angela Anda Brigitta Simon Gabor Soos Jaime A. Teixeira da Silva Zsuzsanna Farkas Laszlo Menyhart Evapotranspiration (ETR), reference evapotranspiration (ET0), and seasonal ETR totals were determined for soybean over two growing seasons, at Keszthely, Hungary, using traditionally...
Thu Aug 06, 2020 03:00
Atmosphere, Vol. 11, Pages 829: Interdecadal Variations in Extreme High–Temperature Events over Southern China in the Early 2000s and the Influence of the Pacific Decadal Oscillation Atmosphere doi: 10.3390/atmos11080829 Authors: Zhu Sun Li Wang This study documents a sudden interdecadal variation in the frequency of extreme high–temperature events (FEHE) over southern China during summer in the early 2000s, which is characterized by a relatively small (large)...
Thu Aug 06, 2020 03:00
Atmosphere, Vol. 11, Pages 828: Spatio-Temporal Variations of Water Vapor Budget over the Tibetan Plateau in Summer and Its Relationship with the Indo-Pacific Warm Pool Atmosphere doi: 10.3390/atmos11080828 Authors: Deli Meng Qing Dong Fanping Kong Zi Yin Yanyan Li Jingyi Liu The water vapor budget (WVB) over the Tibetan Plateau (TP) is closely related to the large-scale atmospheric moisture transportation of the surrounding mainland and oceans, especially for the Indo-Pacific...
Thu Aug 06, 2020 03:00
Bioengineering, Vol. 7, Pages 88: Mechanisms of the Osteogenic Switch of Smooth Muscle Cells in Vascular Calcification: WNT Signaling, BMPs, Mechanotransduction, and EndMT Bioengineering doi: 10.3390/bioengineering7030088 Authors: John Tyson Kaylee Bundy Cameron Roach Hannah Douglas Valerie Ventura Mary Frances Segars Olivia Schwartz C. LaShan Simpson Characterized by the hardening of arteries, vascular calcification is the deposition of hydroxyapatite crystals in...
Thu Aug 06, 2020 03:00
Biology, Vol. 9, Pages 210: The Effect of Bacterial Endotoxin LPS on Serotonergic Modulation of Glutamatergic Synaptic Transmission Biology doi: 10.3390/biology9080210 Authors: Jate Bernard Abigail Greenhalgh Oscar Istas Nicole T. Marguerite Robin L. Cooper The release of the endotoxin lipopolysaccharides (LPS) from gram-negative bacteria is key in the induction of the downstream cytokine release from cells targeting cells throughout the body. However, LPS itself has direct...
Thu Aug 06, 2020 03:00
Biology, Vol. 9, Pages 212: Transcriptome Analysis Reveals That Abeliophyllum distichum Nakai Extract Inhibits RANKL-Mediated Osteoclastogenensis Mainly Through Suppressing Nfatc1 Expression Biology doi: 10.3390/biology9080212 Authors: Kyubin Lee You-Jee Jang Hyerim Lee Eunbin Kim Yeojin Kim Tong-Kewn Yoo Tae Kyung Hyun Jae-Il Park Sun-Ju Yi Kyunghwan Kim Abeliophyllum distichum Nakai is known as a monotypic genus endemic to South Korea. Currently, several...
Thu Aug 06, 2020 03:00
Biology, Vol. 9, Pages 211: Induction of CD4+CD25+ Regulatory T Cells from In Vitro Grown Human Mononuclear Cells by Sparteine Sulfate and Harpagoside Biology doi: 10.3390/biology9080211 Authors: Nour Z. Atwany Seyedeh-Khadijeh Hashemi Manju Nidagodu Jayakumar Mitzi Nagarkatti Prakash Nagarkatti Mona Rushdi Hassuneh Regulatory T cells (Tregs) are key players in the regulation of inflammatory responses. In this study, two natural molecules, namely, sparteine sulfate (SS)...
Thu Aug 06, 2020 03:00
Biology, Vol. 9, Pages 209: Modification and Targeted Design of N-Terminal Truncates Derived from Brevinin with Improved Therapeutic Efficacy Biology doi: 10.3390/biology9080209 Authors: Haoyang He Yuqing Chen Zhuming Ye Xiaoling Chen Chengbang Ma Mei Zhou Xinping Xi James F. Burrows Tianbao Chen Lei Wang Antimicrobial peptides (AMPs) are a class of molecules that play an essential role in innate immune regulation. The Brevinin-1 family are AMPs that show strong...
Thu Aug 06, 2020 03:00
Biomedicines, Vol. 8, Pages 277: Arginine and Endothelial Function Biomedicines doi: 10.3390/biomedicines8080277 Authors: Gambardella Khondkar Morelli Wang Santulli Trimarco Arginine (L-arginine), is an amino acid involved in a number of biological processes, including the biosynthesis of proteins, host immune response, urea cycle, and nitric oxide production. In this systematic review, we focus on the functional role of arginine in the regulation of endothelial...
Thu Aug 06, 2020 03:00
Biomedicines, Vol. 8, Pages 276: Vivostat Platelet-Rich Fibrin® for Complicated or Chronic Wounds—A Pilot Study Biomedicines doi: 10.3390/biomedicines8080276 Authors: Andreas Bayer Gesa Höntsch Mark Kaschwich Annika Dell Markus Siggelkow Rouven Berndt Rene Rusch Juergen Harder Regine Gläser Jochen Cremer Vivostat Platelet-Rich Fibrin® (PRF) is an autologous platelet concentrate used for the local treatment of chronic or complicated wounds. Still, its...
Thu Aug 06, 2020 03:00
Biomimetics, Vol. 5, Pages 38: Development of the Third Generation of the Dual-Reciprocating Drill Biomimetics doi: 10.3390/biomimetics5030038 Authors: Craig Pitcher Mohamed Alkalla Xavier Pang Yang Gao The dual-reciprocating drill (DRD) is a low-mass alternative to traditional drilling techniques biologically inspired by the wood wasp ovipositor, which is used to drill into wood in order to lay its eggs. The DRD reciprocates two halves lined with backwards-facing teeth, enabling...
Thu Aug 06, 2020 03:00
Biomolecules, Vol. 10, Pages 1157: Excretory/Secretory Metabolome of the Zoonotic Roundworm Parasite Toxocara canis Biomolecules doi: 10.3390/biom10081157 Authors: Phurpa Wangchuk Owen Lavers David S. Wishart Alex Loukas Toxocariasis is a zoonotic disease affecting humans that is predominantly caused by Toxocara canis and T. cati, primarily parasites of dogs and cats, respectively. Toxocara generally establishes long-term infections by co-opting its host’s physiological...
Thu Aug 06, 2020 03:00
Biomolecules, Vol. 10, Pages 1156: Structural Features Mediating Zinc Binding and Transfer in the AztABCD Zinc Transporter System Biomolecules doi: 10.3390/biom10081156 Authors: Anusha Meni Erik T. Yukl Many bacteria require ATP binding cassette (ABC) transporters for the import of the essential metal zinc from limited environments. These systems rely on a periplasmic or cell-surface solute binding protein (SBP) to bind zinc with high affinity and specificity. AztABCD is one such...
Thu Aug 06, 2020 03:00
Biomolecules, Vol. 10, Pages 1155: Essentials Oils from Brazilian Eugenia and Syzygium Species and Their Biological Activities Biomolecules doi: 10.3390/biom10081155 Authors: Jamile S. da Costa Ellen de Nazaré S. da Cruz William N. Setzer Joyce Kelly do R. da Silva José Guilherme S. Maia Pablo Luis B. Figueiredo The Eugenia and Syzygium genera include approximately 1000 and 1800 species, respectively, and both belong to the Myrtaceae. Their species present economic and...
Thu Aug 06, 2020 03:00
Biomolecules, Vol. 10, Pages 1153: Microalgae: A Promising Source of Valuable Bioproducts Biomolecules doi: 10.3390/biom10081153 Authors: Vyacheslav Dolganyuk Daria Belova Olga Babich Alexander Prosekov Svetlana Ivanova Dmitriy Katserov Nikolai Patyukov Stanislav Sukhikh Microalgae are a group of autotrophic microorganisms that live in marine, freshwater and soil ecosystems and produce organic substances in the process of photosynthesis. Due to their high metabolic...
Thu Aug 06, 2020 03:00
Biomolecules, Vol. 10, Pages 1152: Folding of Truncated Granulin Peptides Biomolecules doi: 10.3390/biom10081152 Authors: Rozita Takjoo David Wilson Paramjit S. Bansal Alex Loukas Michael J. Smout Norelle L. Daly Granulins are a family of unique protein growth factors which are found in a range of species and have several bioactivities that include cell proliferation and wound healing. They typically contain six disulfide bonds, but the sequences, structures and bioactivities...
Thu Aug 06, 2020 03:00
Biomolecules, Vol. 10, Pages 1154: Not so Slim Anymore—Evidence for the Role of SUMO in the Regulation of Lipid Metabolism Biomolecules doi: 10.3390/biom10081154 Authors: Sapir One of the basic building blocks of all life forms are lipids—biomolecules that dissolve in nonpolar organic solvents but not in water. Lipids have numerous structural, metabolic, and regulative functions in health and disease; thus, complex networks of enzymes coordinate the different compositions...
Thu Aug 06, 2020 03:00
Biomolecules, Vol. 10, Pages 1150: The Potential of Phytochemicals in Oral Cancer Prevention and Therapy: A Review of the Evidence Biomolecules doi: 10.3390/biom10081150 Authors: Tzu-Ying Lee Yu-Hsin Tseng The etiological factors of oral cancer are complex including drinking alcohol, smoking tobacco, betel quid chewing, human papillomavirus infection, and nutritional deficiencies. Understanding the molecular mechanism of oral cancer is vital. The traditional treatment for patients...
Thu Aug 06, 2020 03:00
Biomolecules, Vol. 10, Pages 1151: Hormonal Regulation of Mammalian Adult Neurogenesis: A Multifaceted Mechanism Biomolecules doi: 10.3390/biom10081151 Authors: Claudia Jorgensen Zuoxin Wang Adult neurogenesis—resulting in adult-generated functioning, integrated neurons—is still one of the most captivating research areas of neuroplasticity. The addition of new neurons in adulthood follows a seemingly consistent multi-step process. These neurogenic stages include...
Thu Aug 06, 2020 03:00
Brain Sciences, Vol. 10, Pages 526: Towards Intelligent Data Analytics: A Case Study in Driver Cognitive Load Classification Brain Sciences doi: 10.3390/brainsci10080526 Authors: Shaibal Barua Mobyen Uddin Ahmed Shahina Begum One debatable issue in traffic safety research is that the cognitive load by secondary tasks reduces primary task performance, i.e., driving. In this paper, the study adopted a version of the n-back task as a cognitively loading secondary task on the primary...
Thu Aug 06, 2020 03:00
Brain Sciences, Vol. 10, Pages 527: Comparative Analysis of the Permutation and Multiscale Entropies for Quantification of the Brain Signal Variability in Naturalistic Scenarios Brain Sciences doi: 10.3390/brainsci10080527 Authors: Soheil Keshmiri As alternative entropy estimators, multiscale entropy (MSE) and permutation entropy (PE) are utilized for quantification of the brain function and its signal variability. In this context, their applications are primarily focused on two specific...
Thu Aug 06, 2020 03:00
Brain Sciences, Vol. 10, Pages 524: A 36-Class Bimodal ERP Brain-Computer Interface Using Location-Congruent Auditory-Tactile Stimuli Brain Sciences doi: 10.3390/brainsci10080524 Authors: Boyang Zhang Zongtan Zhou Jing Jiang To date, traditional visual-based event-related potential brain-computer interface (ERP-BCI) systems continue to dominate the mainstream BCI research. However, these conventional BCIs are unsuitable for the individuals who have partly or completely lost their...
Thu Aug 06, 2020 03:00
Brain Sciences, Vol. 10, Pages 523: Analgesic Effects and Impairment in Locomotor Activity Induced by Cannabinoid/Opioid Combinations in Rat Models of Chronic Pain Brain Sciences doi: 10.3390/brainsci10080523 Authors: Mohammad Alsalem Ahmad Altarifi Mansour Haddad Belal Azab Heba Kalbouneh Amer Imraish Tareq Saleh Khalid El-Salem Both opioids and cannabinoids have well-known antinociceptive effects in different animal models of chronic pain. However, unwanted side...
Thu Aug 06, 2020 03:00
Brain Sciences, Vol. 10, Pages 525: Risk Calculators in Bipolar Disorder: A Systematic Review Brain Sciences doi: 10.3390/brainsci10080525 Authors: Joana Silva Ribeiro Daniela Pereira Estela Salagre Manuel Coroa Pedro Santos Oliveira Vítor Santos Nuno Madeira Iria Grande Eduard Vieta Introduction: Early recognition of bipolar disorder improves the prognosis and decreases the burden of the disease. However, there is a significant delay in diagnosis. Multiple risk...
Thu Aug 06, 2020 03:00
Cancers, Vol. 12, Pages 2206: Aberrant BUB1 Overexpression Promotes Mitotic Segregation Errors and Chromosomal Instability in Multiple Myeloma Cancers doi: 10.3390/cancers12082206 Authors: Yuto Fujibayashi Reiko Isa Daichi Nishiyama Natsumi Sakamoto-Inada Norichika Kawasumi Junko Yamaguchi Saeko Kuwahara-Ota Yayoi Matsumura-Kimoto Taku Tsukamoto Yoshiaki Chinen Yuji Shimura Tsutomu Kobayashi Shigeo Horiike Masafumi Taniwaki Hiroshi Handa Junya Kuroda...
Thu Aug 06, 2020 03:00
Cancers, Vol. 12, Pages 2204: Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells Cancers doi: 10.3390/cancers12082204 Authors: Margherita Passariello Cinzia Vetrei Emanuele Sasso Guendalina Froechlich Chiara Gentile Anna Morena D’Alise Nicola Zambrano Elisa Scarselli Alfredo Nicosia Claudia De Lorenzo The cytotoxic T lymphocyte-antigen 4 (CTLA-4) has been considered an IC exclusively expressed on T cells,...
Thu Aug 06, 2020 03:00
Cancers, Vol. 12, Pages 2203: Targeting NF-kB Signaling for Multiple Myeloma Cancers doi: 10.3390/cancers12082203 Authors: Ada Hang-Heng Wong Eun Myoung Shin Vinay Tergaonkar Wee-Joo Chng Multiple myeloma (MM) is the second most common hematologic malignancy in the world. Even though survival rates have significantly risen over the past years, MM remains incurable, and is also far from reaching the point of being managed as a chronic disease. This paper reviews the evolution...
Thu Aug 06, 2020 03:00
Cancers, Vol. 12, Pages 2201: High-Risk Human Papillomavirus and Tobacco Smoke Interactions in Epithelial Carcinogenesis Cancers doi: 10.3390/cancers12082201 Authors: Francisco Aguayo Juan P. Muñoz Francisco Perez-Dominguez Diego Carrillo-Beltrán Carolina Oliva Gloria M. Calaf Rances Blanco Daniela Nuñez-Acurio Cervical, anogenital, and some head and neck cancers (HNC) are etiologically associated with high-risk human papillomavirus (HR-HPV) infection, even though...
Thu Aug 06, 2020 03:00
Cancers, Vol. 12, Pages 2202: Body Mass Index and Total Symptom Burden in Myeloproliferative Neoplasms Discovery of a U-shaped Association Cancers doi: 10.3390/cancers12082202 Authors: Sarah Friis Christensen Robyn Marie Scherber Nana Brochmann Martin Goros Jonathan Gelfond Christen Lykkegaard Andersen Esben Meulengracht Flachs Ruben Mesa Elevated body mass index (BMI) is a global health problem, leading to enhanced mortality and the increased risk of several cancers...
Thu Aug 06, 2020 03:00
Cancers, Vol. 12, Pages 2200: Combination of Peri-Tumoral and Intra-Tumoral Radiomic Features on Bi-Parametric MRI Accurately Stratifies Prostate Cancer Risk: A Multi-Site Study Cancers doi: 10.3390/cancers12082200 Authors: Ahmad Algohary Rakesh Shiradkar Shivani Pahwa Andrei Purysko Sadhna Verma Daniel Moses Ronald Shnier Anne-Maree Haynes Warick Delprado James Thompson Sreeharsha Tirumani Amr Mahran Ardeshir R Rastinehad Lee Ponsky Phillip D. Stricker...
Thu Aug 06, 2020 03:00
Cancers, Vol. 12, Pages 2205: Engineering a Humanised Niche to Support Human Haematopoiesis in Mice: Novel Opportunities in Modelling Cancer Cancers doi: 10.3390/cancers12082205 Authors: Alvaro Sanchez-Herrero Isabel A. Calvo Maria Flandes-Iparraguirre Marietta Landgraf Christoph A. Lahr Abbas Shafiee Froilán Granero-Molto Borja Saez Manuel M. Mazo Bruno Paiva Elena de Juan Pardo Andrew Nicol Felipe Prosper Laura J. Bray Jacqui A. McGovern Despite...
Thu Aug 06, 2020 03:00
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