Related Articles The impact of low mineral content water on cardiac function in diabetic rats: focus on oxidative stress. Mol Cell Biochem. 2020 Jun 20;: Authors: Lalovic D, Jakovljevic V, Radoman K, Bradic J, Jeremic N, Vranic A, Milosavljevic I, Jeremic J, Srejovic I, Turnic TN, Zivkovic V, Stanojevic D, Bolevich S, Djuric DM Abstract The aim of this study was to estimate the effects of natural low mineral water from the source "Sneznik-1/79"...
Mon Jun 22, 2020 14:40
Related Articles Effects of Cerebellar Theta Burst Stimulation on Contralateral Motor Cortex Excitability in Patients with Alzheimer's Disease. Brain Topogr. 2020 Jun 20;: Authors: Di Lorenzo F, Bonnì S, Picazio S, Motta C, Caltagirone C, Martorana A, Koch G Abstract Although the cerebellum is not among the most renowned brain structures affected in Alzheimer`s disease (AD), recent evidence suggest that it undergoes degenerative changes during...
Mon Jun 22, 2020 14:40
Related Articles Safety assessment of chronic hepatitis C treatment using h-FABP and 24-hour ECG Holter monitoring. Pol Merkur Lekarski. 2020 Jun 17;48(285):147-151 Authors: Poliwczak AR, Jędrzejczak-Pospiech K, Błaszczyk J, Białkowska-Warzecha J, Woźny J, Jabkowski M Abstract Every year, 3-4 million people become infected with HCV, most of them are asymptomatic. In more than 20-30 years from infection, it leads to 10-20% of patients with cirrhosis,...
Mon Jun 22, 2020 14:40
Related Articles Serum zonulin measured by enzyme-linked immunosorbent assay may not be a reliable marker of small intestinal permeability in healthy adults. Nutr Res. 2020 May 19;78:82-92 Authors: Tatucu-Babet OA, Forsyth A, Owen E, Navarro-Perez D, Radcliffe J, Benheim D, Mendis H, Jois M, Itsiopoulos C, Tierney AC Abstract The association between intestinal permeability (IP) and body composition remains unclear. The gold standard differential...
Mon Jun 22, 2020 14:40
Related Articles Recent advances in the role of interleukin-6 in health and disease. Curr Opin Pharmacol. 2020 Jun 18;52:47-51 Authors: Peppler WT, Townsend LK, Wright DC Abstract Interleukin-6 (IL-6) is a pleotropic cytokine, and in this review, we highlight recent studies focusing on the role of IL-6 in health and disease. IL-6 is known as an exercise-inducible myokine, and in rodents it was identified that a lactate-dependent increase in...
Mon Jun 22, 2020 14:40
Related Articles Lnc-M2 controls M2 macrophage differentiation via the PKA/CREB pathway. Mol Immunol. 2020 Jun 18;124:142-152 Authors: Chen Y, Li H, Ding T, Li J, Zhang Y, Wang J, Yang X, Chong T, Long Y, Li X, Gao F, Lyu X Abstract Long noncoding RNAs (lncRNAs) play an indispensable role in the process of M1 macrophage via regulating the development of macrophages and their responses to bacterial pathogens and viral infections. However, there...
Mon Jun 22, 2020 14:40
Related Articles Role of VPS13, a protein with similarity to ATG2, in physiology and disease. Curr Opin Genet Dev. 2020 Jun 18;65:61-68 Authors: Ugur B, Hancock-Cerutti W, Leonzino M, De Camilli P Abstract The evolutionarily conserved VPS13 family proteins have been implicated in several cellular processes. Mutations in each of the four human VPS13s cause neurodevelopmental or neurodegenerative disorders. Until recently, the molecular function...
Mon Jun 22, 2020 14:40
Related Articles Comparative analysis of gene expression between articular cartilage-derived cells to assess suitability of fibronectin adhesion assay to enrich chondroprogenitors. Knee. 2020 Jun;27(3):755-759 Authors: Kachroo U, Vinod E Abstract BACKGROUND: Enhanced chondrogenesis and reduction in hypertrophy are essential pre-requisites for cell-based therapy in regenerative research for cartilage loss. Chondroprogenitors, isolated by fibronectin...
Mon Jun 22, 2020 14:40
Related Articles Total facial nerve injury during mandibular distraction osteogenesis. Int J Pediatr Otorhinolaryngol. 2020 Jun 13;136:110182 Authors: Belcher RH, Phillips JD Abstract INTRODUCTION: Over the last 10-15 years, usage of internal mandibular distraction systems has increased in the pediatric population, particularly for craniofacial syndromes. Mandibular distraction osteogenesis (MDO) has been shown to be effective in avoiding tracheostomy...
Mon Jun 22, 2020 14:38
Related Articles An Unusual Intraoral Lipoma: A Case Report and Literature Review. Am J Case Rep. 2020 Jun 21;21:e923503 Authors: De Sanctis CM, Zara F, Sfasciotti GL Abstract BACKGROUND Lipoma is a painless tumor derived from mesenchymal connective tissue. It manifests itself on soft tissue and is characterized by a slow and circumscribed growth. Its incidence in the oral cavity is relatively low (1-4%). Despite the fact that it poses very...
Mon Jun 22, 2020 14:31
Τα κουνούπια έχουν αποτελέσει πονοκέφαλο για τον άνθρωπο μάλλον καθ’ όλη τη διάρκεια της ύπαρξής του. Όχι άδικα: τα έντομα είναι τα πιο επικίνδυνα ζώα του κόσμου, αφού μπορούν να μεταδώσουν θανατηφόρες ασθένειες όπως η ελονοσία, ο κίτρινος πυρετός και άλλα. Ενώ τα χημικά απωθητικά που περιέχουν DEET και χρησιμοποιούνται ευρέως είναι αποτελεσματικά και με αμελητέες επιπτώσεις στην υγεία, πολλοί άνθρωποι καταφεύγουν σε φυσικές λύσεις όπως τα φυτά και τα αιθέρια έλαια για μια ασφαλέστερη μέθοδο απώθησης...
Mon Jun 22, 2020 12:55
Οι θετικές προσδοκίες ότι ένα φάρμακο είναι αποτελεσματικό μπορεί να το καταστήσουν πιο δραστικό, ακόμη και αν οι ασθενείς ενημερωθούν για το φαινόμενο placebo. Το αντίθετο, το φαινόμενο nocebo, δρα με τον ίδιο τρόπο, δηλαδή με την προσδοκία ότι μια θεραπεία θα είναι αναποτελεσματική κάτι που τελικά επιβεβαιώνεται. Η ψυχολόγος υγείας Stefanie Meeuwis από το Πανεπιστήμιο του Leiden βρήκε αρκετές αποδείξεις για τη δράση του placebo και του nocebo σε σχετική έρευνα. Το ενδιαφέρον της ερευνήτριας ήταν...
Mon Jun 22, 2020 12:35
Θα ανέμενε κανείς οι αλλαγές που συνοδεύουν κάθε εποχή γύρω από τα ήθη, τα κοινωνικά πρότυπα και την κοινωνική κατασκευή του φύλου να έχει αντίστοιχη επίδραση στα κριτήρια επιλογής συντρόφου. Ποια είναι η αλήθεια; Νέα έρευνα που δημοσιεύτηκε στο Psychological Science, αναζήτησε την απάντηση μέσα από την έρευνα για τα κριτήρια επιλογής συντρόφου περισσότερων από 14.000 ετεροφυλόφιλων κατοίκων 45 χωρών. Τα ευρήματα είναι εντυπωσιακά. Όπως φάνηκε, τίποτα δεν έχει αλλάξει εδώ και πάνω από 30 χρόνια:...
Mon Jun 22, 2020 10:38
Ο κίνδυνος των γυναικών να νοσήσουν από κάποια καρδιαγγειακή πάθηση και να πεθάνουν από αυτήν, είναι μικρότερος από εκείνων των ανδρών της ίδιας ηλικίας, ανεξάρτητα από το σε ποια χώρα ζουν. Αυτό φαίνεται από μια σουηδική μελέτη που έγινε σε περισσότερους από 160.000 άνδρες και γυναίκες σε 27 χώρες και η οποία δημοσιεύθηκε πρόσφατα στο έγκριτο The Lancet και μπορείτε να βρείτε εδώ. Η έρευνα έθεσε τους συμμετέχοντες στο μικροσκόπιο για περισσότερα από 10 χρόνια, για τα συμβάντα της καρδιακής προσβολής,...
Mon Jun 22, 2020 09:15
Ο συνδυασμός περισσότερων υγιεινών συμπεριφορών στον τρόπο ζωής σχετίστηκε με σημαντικά χαμηλότερο κίνδυνο για τη νόσο Αλτσχάιμερ σε μια μελέτη που περιελάμβανε δεδομένα από σχεδόν 3.000 συμμετέχοντες και δημοσιεύθηκε στο Neurology της Αμερικανικής Ακαδημίας Νευρολογίας. Όσοι από αυτούς ακολουθούσαν πιστά τέσσερις ή και τις πέντε από τις συγκεκριμένες υγιεινές συμπεριφορές που αναλύονταν στη μελέτη παρουσίασαν 60% μικρότερο κίνδυνο να εκδηλώσουν τη νόσο. Οι συμπεριφορές αυτές ήταν η φυσική δραστηριότητα,...
Mon Jun 22, 2020 08:59
Η μάσκα αποτελεί το πλέον σημαντικό μέτρο για να προφυλαχθούμε από τον νέο κορωνοϊό. Τι συμβαίνει όμως όταν η προστασία μας γίνεται εμπόδιο στην επικοινωνία; Η κάλυψη του στόματος με τη μάσκα αποτελεί φραγμό στην επικοινωνία μέσω χειλεανάγνωσης, μιας μεθόδου που εφαρμόζουν οι ασθενείς με κώφωση για την κατανόηση του συνομιλητή τους. Τη λύση στο ασύμβατο ατομικής προστασίας με μάσκα και επικοινωνίας βρήκε η Αμερικανίδα Ingrid Helton, σχεδιάστρια κοστουμιών στην Όπερα του San Diego, η οποία σχεδίασε...
Mon Jun 22, 2020 08:42
Έρευνες έχουν δείξει πως ο μεγάλης διάρκειας ύπνος μπορεί να προσφέρει σημαντικά οφέλη στον άνθρωπο. Τι συμβαίνει, ωστόσο, όταν κανείς στερείται ώρες από έναν πλήρη και καλό ύπνο, ιδιαίτερα σε μια εποχή που ο ανεπαρκής ύπνος αναδεικνύεται σε επιδημία στον δυτικό κόσμο, προσβάλλοντας ιδιαίτερα τους νέους, αλλά και τους ενήλικες κάθε ηλικίας. Πρόσφατη έρευνα έδειξε πως η «επιδημία αϋπνίας» επιδρά αρνητικά στην ψυχολογική μας διάθεση, όχι σε βαθμό πρόκλησης αρνητικών συναισθημάτων όπως στην περίπτωση...
Mon Jun 22, 2020 08:06
Abstract Background The acute: chronic workload ratio (ACWR) is an index of the acute workload relative to the cumulative chronic workloads. The monitoring of physical workloads using the ACWR has emerged and been hypothesized as a useful tool for coaches and athletes to optimize performance while aiming to reduce the risk of potentially preventable load-driven injuries. ...
Mon Jun 22, 2020 03:00
Purpose. The aim of this study was to evaluate the diagnostic and prognostic value of IL-6 and sTREM-1 in the course of SIRS and sepsis in children with reference to routinely used CRP and PCT. Methods. A prospective study included 180 patients at the ages from 2 months to 18 years hospitalized due to fever from November 2015 to January 2017. Forty-nine children without fever hospitalized due to noninfectious causes formed the control group. IL-6 and sTREM-1 serum concentrations were assessed with...
Mon Jun 22, 2020 12:05
Background. Cerebral malaria (CM), a reversible encephalopathy affecting young children, is a medical emergency requiring rapid clinical assessment and treatment. However, understanding of the genes/proteins and the biological pathways involved in the disease outcome is still limited. Methods. We have performed a whole transcriptomic analysis of blood samples from Malian children with CM or uncomplicated malaria (UM). Hierarchical clustering and pathway, network, and upstream regulator analyses were...
Mon Jun 22, 2020 11:50
Receptor internalization and degradation (RID), is a transmembrane protein coded within the E3 region expression cassette of adenoviruses. RID downregulates the cell surface expression of epidermal growth factor receptor (EGFR), tumor necrosis factor receptor (TNFR), and apoptosis antigen 1 (FAS), causing a reduction of the effects of their respective ligands. In addition, RID inhibits apoptosis by decreasing the secretion of TNF-related apoptosis-inducing ligand (TRAIL) by normal tissue cells. In...
Mon Jun 22, 2020 11:50
Related Articles Impact of Personal Protective Equipment on Surgical Performance During the COVID-19 Pandemic. World J Surg. 2020 Jun 20;: Authors: Yánez Benítez C, Güemes A, Aranda J, Ribeiro M, Ottolino P, Di Saverio S, Alexandrino H, Ponchietti L, Blas JL, International Cooperation Group on PPE and Emergency Surgery, Ramos JP, Rangelova E, Muñoz M, Yánez C Abstract BACKGROUND: The Severe Acute Respiratory Syndrome Coronavirus 2 pandemic has...
Mon Jun 22, 2020 14:27
Related Articles The Risk of Second Primary Malignancies in Patients With Lung Neuroendocrine Tumors: A Population-Based Study on SEER Database. Curr Probl Cancer. 2020 Jun 12;:100613 Authors: Bu X, Wang X, Wei L, Liu J, Chen M Abstract PURPOSE: We investigated the at-risk sites of second primary malignancies (SPMs) and evaluate the risk factors of SPMs among lung neuroendocrine tumors (LNETs) survivors by using the surveillance, epidemiology,...
Mon Jun 22, 2020 14:22
Related Articles Correlation between private education costs and parental depression in South Korea. BMC Public Health. 2020 Jun 20;20(1):972 Authors: Oh BC, Yeon JY, Lee HS, Lee DW, Park EC Abstract BACKGROUND: In Korea, higher education has rapidly grown influenced by sociocultural tradition. Parents invest a significant portion of their household income in their children's education. Private education has been considered to greatly affect...
Mon Jun 22, 2020 18:15
Related Articles Comparison of test results from two separate video head impulse test systems in a cohort of patients diagnosed with a unilateral vestibular schwannoma. Eur Arch Otorhinolaryngol. 2020 Jun 20;: Authors: Aalling M, Skals RK, Abrahamsen ER, Hougaard DD Abstract PURPOSE: Video head impulse testing (vHIT) is a relatively new technology enabling evaluation of vestibular function. The aim of this study was to compare the test results...
Mon Jun 22, 2020 18:03
Related Articles The origin structure of each finger in the flexor digitorum superficialis muscle. Surg Radiol Anat. 2020 Jun 20;: Authors: Matsuzawa K, Edama M, Ikezu M, Kaneko F, Hirabayashi R, Kageyama I Abstract PURPOSE: The flexor digitorum superficialis muscle (FDS) is considered the most important of the forearm flexors for maintaining elbow valgus stability. However, the relationships between the origin structure of each finger...
Mon Jun 22, 2020 18:02
Related Articles Incidence and morphology of the incisive suture in CT scanning of young children and human fetuses. Surg Radiol Anat. 2020 Jun 20;: Authors: Nicol P, Elmaleh-Bergès M, Sadoine J, Slimani L, Vacher C Abstract PURPOSE: Incisive suture is a suture classically described on the oral face of the palate in fetuses and young children. The aim of our study was to describe the evolution of the incisive suture in human fetuses and...
Mon Jun 22, 2020 18:02
Related Articles Fraction-Variant Beam Orientation Optimization for Intensity-Modulated Proton Therapy. Med Phys. 2020 Jun 21;: Authors: Gu W, O'Connor D, Ruan D, Zou W, Dong L, Sheng K Abstract PURPOSE: To achieve a superior balance between dosimetry and the delivery efficiency of intensity modulated proton therapy (IMPT) using as few beams as possible in a single fraction, we optimally vary beams in different fractions. METHODS: In...
Mon Jun 22, 2020 18:00
Related Articles More than smell - COVID-19 is associated with severe impairment of smell, taste, and chemesthesis. Chem Senses. 2020 Jun 20;: Authors: Parma V, Ohla K, Veldhuizen MG, Niv MY, Kelly CE, Bakke AJ, Cooper KW, Bouysset C, Pirastu N, Dibattista M, Kaur R, Liuzza MT, Pepino MY, Schöpf V, Pereda-Loth V, Olsson SB, Gerkin RC, Rohlfs Domínguez P, Albayay J, Farruggia MC, Bhutani S, Fjaeldstad AW, Kumar R, Menini A, Bensafi M, Sandell M, Konstantinidis...
Mon Jun 22, 2020 18:00
Related Articles Letter to the Editor Regarding 'Bone metastasis of limb segments: Is mesometastasis another poor prognostic factor of cancer patients?' Jpn J Clin Oncol. 2020 Jun 22;: Authors: Ren S, Wang Z PMID: 32564091 [PubMed - as supplied by publisher]
Mon Jun 22, 2020 14:55
Related Articles Understanding help-seeking behaviour in relation to psychosocial support services among Japanese cancer patients. Jpn J Clin Oncol. 2020 Jun 22;: Authors: Matsui T, Hirai K, Gondo Y, Sato S Abstract BACKGROUND: There are various psychosocial support services for cancer patients in Japan; however, their utilization rate is lower than in Western countries. The aim of this study was to investigate the actual status of the utilization...
Mon Jun 22, 2020 14:55
Related Articles Evaluation of safety and diagnostic performance for flexible hysteroscopy in 1591 outpatient cases. Jpn J Clin Oncol. 2020 Jun 22;: Authors: Kobayashi Y, Tsuji K, Nakamura K, Nagai S, Takahashi T, Kobayashi A, Anko M, Hirano T, Watanabe K, Matoba Y, Kunitomi H, Adachi M, Yamagami W, Tominaga E, Banno K, Aoki D Abstract BACKGROUND: To date, only few large studies are available concerning the safety and diagnostic concordance...
Mon Jun 22, 2020 14:55
Related Articles Prognostic value of lymphocyte-to-C-reactive protein ratio in patients with gastric cancer after surgery: a multicentre study. Jpn J Clin Oncol. 2020 Jun 22;: Authors: Cheng CB, Zhang QX, Zhuang LP, Sun JW Abstract OBJECTIVE: The immune inflammation-based score is recognized as a prognostic marker for cancer. However, the most accurate prognostic marker for patients with gastric cancer remains undetermined. We aimed to evaluate...
Mon Jun 22, 2020 14:55
Related Articles Author's reply to 'bone metastasis of limb segments: is mesometastasis another poor prognostic factor of cancer patients?' Jpn J Clin Oncol. 2020 Jun 22;: Authors: Tani S, Morizaki Y, Uehara K, Sawada R, Kobayashi H, Shinoda Y, Kawano H, Tanaka S PMID: 32564082 [PubMed - as supplied by publisher]
Mon Jun 22, 2020 14:55
Related Articles The European Portuguese version of the Reproductive Concerns After Cancer Scale (RCACS): A psychometric validation for young adult female cancer survivors. Eur J Oncol Nurs. 2020 Jun 12;47:101781 Authors: Bártolo A, Santos IM, Valério E, Costa A, Reis S, Raposo S, Monteiro S Abstract PURPOSE: The purpose of this study was to evaluate the psychometric properties of the Portuguese version of the 18-item Reproductive Concerns After...
Mon Jun 22, 2020 15:17
Related Articles Patient-centered care coordination, education and counseling of patients treated with oral anticancer drugs: An importance-performance analysis. Eur J Oncol Nurs. 2020 May 04;47:101765 Authors: Kinnaer LM, Nelis M, Van Hecke A, Foulon V Abstract PURPOSE: To analyse the importance and performance of key elements in patient-centered care coordination, education and counseling of patients treated with oral anticancer drugs. ...
Mon Jun 22, 2020 15:17
Related Articles A rare presentation of hepatolithiasis in an adolescent patient: A case report. Int J Surg Case Rep. 2020 Jun 12;72:343-345 Authors: Freise J, Mena J, Wen KW, Stoller M, Ho S, Corvera C Abstract INTRODUCTION: Hepatolithiasis (intrahepatic stones) is rare in adolescent patients and requires complex management strategies to prevent recurrent infections and progression to hepatic fibrosis. Surgical management is often required....
Mon Jun 22, 2020 15:17
Nature Communications, Published online: 22 June 2020; doi:10.1038/s41467-020-16904-3Single cell RNA-seq is a powerful method to assign cell identity, but the purity of cell clusters arising from this data is not clear. Here the authors present an entropy-based statistic called ROGUE to quantify the purity of cell clusters, and identify subtypes within clusters.
Mon Jun 22, 2020 03:00
Nature Communications, Published online: 22 June 2020; doi:10.1038/s41467-020-16901-6Author Correction: HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis
Mon Jun 22, 2020 03:00
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