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Δευτέρα 22 Ιουνίου 2020


Sturge-Weber syndrome: an update on the relevant issues for neurosurgeons.
Related Articles Sturge-Weber syndrome: an update on the relevant issues for neurosurgeons. Childs Nerv Syst. 2020 Jun 21;: Authors: Bianchi F, Auricchio AM, Battaglia DI, Chieffo DRP, Massimi L Abstract PURPOSE: Sturge-Weber syndrome (SWS) is a neurocutaneous facomatosis characterized by facial and leptomeningeal angioma, glaucoma, seizures, and neurological disability. Therefore, a challenging multidisciplinary interaction is required for...
pubmed: epilepsy treatment
Mon Jun 22, 2020 16:34
Expert opinion: Proposed diagnostic and treatment algorithms for Lennox-Gastaut syndrome in adult patients.
Related Articles Expert opinion: Proposed diagnostic and treatment algorithms for Lennox-Gastaut syndrome in adult patients. Epilepsy Behav. 2020 Jun 18;110:107146 Authors: Montouris G, Aboumatar S, Burdette D, Kothare S, Kuzniecky R, Rosenfeld W, Chung S Abstract Lennox-Gastaut syndrome (LGS) is a severe developmental epileptic encephalopathy diagnosed in childhood that persists through adolescence and into adulthood. While the characteristics...
pubmed: epilepsy treatment
Mon Jun 22, 2020 16:34
Suicidal behavior among people with epilepsy in Northwest Ethiopia: A comparative cross-sectional study.
Related Articles Suicidal behavior among people with epilepsy in Northwest Ethiopia: A comparative cross-sectional study. Epilepsy Behav. 2020 Jun 18;111:107233 Authors: Mekonen T, Getnet A, Belete A, Menberu M, Fekadu W Abstract INTRODUCTION: Premature mortality is common in people with epilepsy, but the causes vary where suicide is considered as one of the commonest. OBJECTIVE: The objective of this study was to compare suicidal behavior...
pubmed: epilepsy treatment
Mon Jun 22, 2020 16:34
Control of taeniasis and cysticercosis in China.
Related Articles Control of taeniasis and cysticercosis in China. Adv Parasitol. 2020;110:289-317 Authors: Qian MB, Xiao N, Li SZ, Abela-Ridder B, Carabin H, Fahrion AS, Engels D, Zhou XN Abstract National surveys suggest that the prevalence of taeniasis has considerably decreased in China, while reported cases indicated T. solium cysticercosis was historically highly endemic in northeastern, central and southwestern China. The high prevalence...
pubmed: epilepsy treatment
Mon Jun 22, 2020 16:34
Maximizing placebo response in neurological clinical practice.
Related Articles Maximizing placebo response in neurological clinical practice. Int Rev Neurobiol. 2020;153:71-101 Authors: Mariani LL, Corvol JC Abstract The placebo effect is a widely recognized phenomenon in clinical research, with a negative perception that it could hide the "true" drug effect. In clinical care its positive potential to increase known drug effects has been neglected for too long. The placebo and nocebo responses have been...
pubmed: epilepsy treatment
Mon Jun 22, 2020 16:34
Durvalumab-Induced Diffuse Alveolar Hemorrhage: An Autopsy Case Report
Durvalumab, a programmed cell death ligand 1 inhibitor, induces various immune-related adverse events (irAEs), including lung injury. However, diffuse alveolar hemorrhage (DAH) is a rare type of lung injury due to immune checkpoint inhibitors. A 76-year-old man with c-stage IIIA squamous cell carcinoma of the lung received maintenance durvalumab therapy after chemoradiotherapy. He developed dyspnea and malaise after 11 cycles of durvalumab. Chest computed tomography showed rapidly spreading bilateral...
Case Reports in Oncology
Mon Jun 22, 2020 11:23
Correction to: The old CEACAMs find their new role in tumor immunotherapy
Correction is needed to the original version of this article.
Latest Results for Investigational New Drugs
Mon Jun 22, 2020 03:00
Quilting suture versus conventional closure in prevention of seroma after total mastectomy and axillary dissection in breast cancer patients
This randomized control study compares quilting suture and conventional closure to prevent seroma after total mastectomy and level 2 axillary dissection for breast cancer. The incidence of seroma is higher in conventional group. Seroma is treated with more ease in the quilting group as the frequency and amount of aspiration are lower and less frequent follow‐up visits are required. Abstract Background Total mastectomy and axillary dissection is a common procedure for breast cancer patients...
ANZ Journal of Surgery
Sun Jun 21, 2020 13:24
Prospective evaluation of the impact of human papilloma virus status and small node size on the diagnostic accuracy of 18F‐fluorodeoxyglucose positron emission tomography/computed tomography for primary head and neck squamous cell carcinoma
Staging of head and neck squamous cell carcinoma may be affected by node size and human papilloma virus (HPV) status. Our study ascertains the diagnostic accuracy of 18F‐fluorodeoxyglucose positron emission tomography/computed tomography with regards to these factors. It shows that subcentimetre nodes and HPV negativity are associated with decreased accuracy of 18F‐fluorodeoxyglucose. Abstract Background Fluorodeoxyglucose‐positron emission tomography/computed tomography (FDG‐PET/CT)...
ANZ Journal of Surgery
Sun Jun 21, 2020 13:20
Design and establishment of a cancer registry: a literature review
Establishment of a cancer registry is a complex process that requires substantial resources and careful planning. An electronic search was completed to examine the primary literature for evidence‐based recommendations on how to design and establish a cancer registry, with a focus on literature which analyses the performance and usefulness of already established registries or guidelines. Nine articles were included in the review and it was concluded that there is a large gap in the primary literature...
ANZ Journal of Surgery
Sun Jun 21, 2020 13:19
Correlation between computed tomography volumetry and nuclear medicine split renal function in live kidney donation: a single‐centre experience
Current computed tomography technology allows accurate assessment of renal volumes that correlate well with dimercaptosuccinic acid split function. The decision of which kidney to donate is based on function and anatomy which can be achieved with a computed tomography angiogram only. Abstract Background Potential live renal donors undergo both renal computed tomography angiogram (CTA) and nuclear imaging dimercaptosuccinic acid (DMSA) scans. Each kidney's renal function and vascular...
ANZ Journal of Surgery
Sun Jun 21, 2020 13:18
Study of anorectal dynamics in patients undergoing laparoscopic ultra‐low resection and transanal intersphincteric resection for rectal cancer
Laparoscopic total mesorectal excision combined with intersphincteric resection is technically safe and feasible for the treatment of ultra‐low rectal cancer. The curative effect is encouraging, but surgical indications should be determined. Abstract Background Quite a few studies on anal functions after open total mesorectal excision combined with transanal intersphincteric resection (ISR) have been reported, but there is little literature on anal function after laparoscopic total mesorectal...
ANZ Journal of Surgery
Sun Jun 21, 2020 13:14
How to do a handsewn reversal of ileostomy: a systematic technique for new surgical trainees
A straightforward, systematic and reproducible framework for junior registrars to adopt when learning the handsewn ileostomy closure technique.
ANZ Journal of Surgery
Sun Jun 21, 2020 12:00
Response of Retinal Pigment Epithelium (RPE)‐Choroid Explants to Thermal Stimulation Therapy of the RPE (TSR)
Background and Objectives The thermal stimulation therapy of the retinal pigment epithelium (TSR) is a sublethal laser technique for thermal stimulation of the retinal pigment epithelium (RPE)‐Bruch's membrane (BrM)‐complex. The aim of this study was to investigate the influence of TSR on the release of age‐related macular degeneration (AMD)‐relevant cell mediators. Study Design/Materials and Methods Porcine RPE‐BrM‐choroid explants were irradiated with a 532 nm continuous wave laser using...
Lasers in Surgery and Medicine
Sun Jun 21, 2020 18:40
Treatment with flow diverter stent during pregnancy
Abstract Intracranial aneurysms are rarely diagnosed during pregnancy. If treatment is necessary, surgery was traditionally preferred over embolization in case of ongoing pregnancy, due to concerns regarding foetal radiation exposure. We present a case of 21 mm unruptured carotid-ophthalmic aneurysm diagnosed during pregnancy and treated with flow diversion. Foetal radiation dose was estimated between 1 and 5 mGy, well below recommended limits. Double antiplatelet therapy with...
Neuroradiology
Mon Jun 22, 2020 03:00
Expanding the phenotypic spectrum of lipomatosis of the sciatic nerve: Early‐onset colonic diverticular disease
Lipomatosis of the sciatic nerve and early‐onset colonic diverticular disease. Nerves innervating descending and sigmoid colon that are affected by lipomatosis of nerve might influence directly or indirectly colon and cause the development in early‐onset diverticular disease. Abstract Background Lipomatosis of nerve (LN) is a complex peripheral nerve disorder characterized by fibrofatty nerve enlargement. MRI of this pathology is pathognomonic and obviates a diagnostic biopsy. Mutation...
The European Gastrointestinal Motility Society
Sun Jun 21, 2020 18:21
Current Status of Dyslipidemia Treatment for Stroke Prevention
Abstract Purpose of Review Elevated cholesterol is an established risk factor for ischemic stroke. The value of statins for stroke prevention has been clear for more than a decade. Recent Findings However, the use of new medication combinations such as ezetimibe or proprotein convertase subtilisin–kexin type 9 inhibitors plus statins...
Current Neurology and Neuroscience Reports
Mon Jun 22, 2020 03:00
A biomechanical analysis of 3D stress and strain patterns in patellar tendon during knee flexion
Abstract Patellar tendinopathy is among the most widespread patellar tendon diseases in athletes that participate in activities involving running and jumping. Although their symptoms can be detected, especially at the inferior pole of the patella, their biomechanical cause remains unknown. In this study, a three‐dimensional finite element model of knee complex was developed to investigate principal stress and strain distributions in the patellar tendon during 0°‐90° knee flexion and slow and fast...
International Journal for Numerical Methods in Biomedical Engineering
Sun Jun 21, 2020 18:08
The effect of inadequate access to peri‐implant hygiene on marginal bone level. A 4‐year cohort prospective study
Abstract Objective The objective of this four‐year cohort prospective study was to evaluate the effect of inadequate access to peri‐implant hygiene on marginal bone level (MBL). Material and Methods Forty‐one partially edentulous patients (16 males and 25 females, aged 49.8 ± 11.9 years) who had implants with at least one year in function were selected. Patients were clinically and radiographically evaluated at three different times: baseline (T0), 2‐year (T1), and 4‐year (T2) follow‐up...
Clinical Oral Implants Research
Sun Jun 21, 2020 12:19
Is 0.5% Hydrogen Peroxide Effective against SARS‐CoV‐2?
ABSTRACT SARS‐CoV‐2 is mostly transmitted through respiratory droplets and contact routes, but the WHO also states that “airborne transmission may be possible in specific circumstances and settings in which procedures or support treatments that generate aerosols are performed” (WHO, 2020).
Oral Diseases
Sun Jun 21, 2020 21:39
Expression Levels of SIX1, ME2 and AP2M1 in Adenoid Cystic Carcinoma and Mucoepidermoid Carcinoma
Abstract Objective Adenoid cystic carcinoma (AdCC) and mucoepidermoid carcinoma (MEC) are the most frequent malignancies in the salivary glands. The purpose of this study was to explore the roles of sineoculis homeobox homolog 1 (SIX1), malic enzyme 2 (ME2) and AP‐2 complex subunit mu (AP2M1) in AdCC and MEC, as well as the potential relationship between SIX1, ME2, AP2M1 and proliferation marker cyclin D1. Material and methods Immunohistochemistry was performed on human salivary gland tissue...
Oral Diseases
Sun Jun 21, 2020 13:37
SARS‐CoV‐2 and Oral Ulcers; a Causative Agent or a Predisposing Factor?
Abstract Earlier reports on COVID‐19 have reported certain orofacial manifestations like taste loss and salivary gland infection (Dar‐Odeh et al, 2020). More recently, two studies from Spain and France reported oral ulcerative lesions in COVID‐19 patients ( Chaux‐Bodard et al, 2020; Carreras‐ Presas et al, 2020). The study from Spain included three patients. The first two cases (males) were suspected cases of COVID‐19 as testing was not done for them. Intraorally, they had oral ulcers affecting...
Oral Diseases
Sun Jun 21, 2020 12:18
Metamizole‐induced reactions as a paradigm of drug hypersensitivity: non‐allergic reactions, anaphylaxis, and delayed‐type allergy
Abstract Metamizole belongs to the group of non‐opioid analgesics and, as for other non‐steroidal anti‐inflammatory drugs (NSAID) such as acetylsalicylic acid, diclofenac or ibuprofen, both isoforms of cyclooxygenase are inhibited. Metamizole is an important trigger of non‐allergic and allergic hypersensitivity reactions and has been withdrawn from the US, Australian, and UK market due to the risk of agranulocytosis, but is still available and broadly used in many countries of Europe, Central and...
Clinical & Experimental Allergy
Sun Jun 21, 2020 11:04
Enantiomeric Discrimination by Surface‐Enhanced Raman Scattering–Chiral Anisotropy of Chiral Nanostructured Gold Films
Absolution by SERS : A surface‐enhanced Raman scattering chiral anisotropy effect is presented that combines chiral discrimination and surface Raman scattering enhancement on chiral nanostructured Au films. It is applied in the normal Raman scattering system to identify the absolute configuration and composition of enantiomers, overcoming disadvantages of polarimeter systems and chromatography. Abstract A surface‐enhanced Raman scattering‐chiral anisotropy (SERS‐ChA) effect is reported...
Angewandte Chemie International Edition
Sun Jun 21, 2020 21:46
Patients’ communication preferences for receiving a cancer diagnosis: Differences depending on cancer stage
Abstract Objective This study aimed to identify communication preferences for receiving a cancer diagnosis in South Korean patients and explore differences depending on cancer stage—with or without recurrence/metastasis. Methods A total of 312 patients from five cancer centers in South Korea completed the Korean version of the Measure of Patients’ Preferences questionnaire, Mini‐Mental Adjustment to Cancer scale, Insomnia Severity Index, and Hospital Anxiety and Depression Scale. Results...
Psycho-Oncology
Sun Jun 21, 2020 18:50
Decision‐making in cancer care for people living with dementia
Abstract Objective Increasing numbers of people are expected to live with comorbid cancer and dementia. Cancer treatment decision‐making for these individuals is complex, particularly for those lacking capacity, requiring support across the cancer care pathway. There is little research to inform practice in this area. This ethnographic study reports on the cancer decision‐making experiences of people with cancer and dementia, their families, and healthcare staff. Methods Participant observations,...
Psycho-Oncology
Sun Jun 21, 2020 18:48
Interventions to control children's screen use and their effect on sleep: A systematic review and meta‐analysis
Abstract Prolonged viewing of screen‐based media is associated with poor sleep in children. Previous systematic reviews have analysed the effectiveness of interventions that aim to limit children's screen use; however, none have evaluated its effect on sleep. The aim of this systematic review was to evaluate the effect of interventions that incorporate strategies to control children's screen use on screen use and sleep. The databases Pubmed, Embase, Eric, Scopus and PsycInfo were searched during...
Journal of Sleep Research
Sun Jun 21, 2020 20:50
Effects of acute sleep deprivation on H reflex and V wave
Abstract The impact of sleep deprivation on muscular strength and power remains poorly understood. We aimed to determine the acute effects of 24 hr of sleep deprivation on H‐reflex and V‐wave excitability. Fourteen healthy young adults (eight men, six women) were included. Participants visited the laboratory on two different occasions, without and with 24 hr of sleep deprivation. In each session, participants were tested for maximal voluntary contraction (MVC) of the plantar flexors and dorsiflexors,...
Journal of Sleep Research
Sun Jun 21, 2020 16:25
Telephone‐guided imagery rehearsal therapy for nightmares: Efficacy and mediator of change
Summary The currently best‐supported psychological treatment for nightmares is imagery rehearsal therapy. The problem, however, is that not enough trained practitioners are available to offer this treatment. A possible solution is to conduct imagery rehearsal therapy in a guided self‐help format. In the current study, 70 participants with nightmares according to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders were randomized to either telephone‐guided imagery rehearsal...
Journal of Sleep Research
Sun Jun 21, 2020 15:38
Cumulative incidence and relative risk of sleep problems among children and adolescents with newly diagnosed neurodevelopmental disorders: A nationwide register‐based study
Abstract We estimated the absolute and relative risk of sleep problems in children and adolescents with newly diagnosed neurodevelopmental disorders. This was a population‐based cohort study of individuals born in Denmark in 1993–2014 and followed in nationwide registers in 2011–2016. We estimated the 5‐year cumulative incidence of sleep problems in incident cases of attention‐deficit/hyperactivity disorder (ADHD; n  = 12,844), autism spectrum disorder (ASD; n  = 8,073), oppositional defiant disorder/conduct...
Journal of Sleep Research
Sun Jun 21, 2020 13:44
A biologically constrained spiking neural network model of the primate basal ganglia with overlapping pathways exhibits action selection
Abstract Action selection has been hypothesised to be a key function of the basal ganglia, yet the nuclei involved, their interactions and the importance of the direct/indirect pathways segregation in such process remain debated. Here we design a spiking computational model of the monkey basal ganglia derived from a previously published population model, initially parameterized to reproduce electrophysiological activity at rest, and to embody as much quantitative anatomical data as possible. As...
European Journal of Neuroscience
Sun Jun 21, 2020 22:49
20Q: Why All Audiologists Should be Administering Balance Screenings
A discussion of why all audiologists should be conducting balance screenings, written in an engaging Q & A format.
Audiology
Mon Jun 22, 2020 07:00
Surgical correction of ankylosed TMJ in a child: case report
Abstract The temporomandibular joint (TMJ) ankylosis describes the bone or fibrous adhesion of the TMJ components, with functional impairment. The present report shows the surgical correction the TMJ ankylosis due to a condyle fracture in a child. A 12-year-old patient, female, attended to the Oral and Maxillofacial Surgery Department of the Clinical Hospital/Federal University of Uberlândia, showing severe mouth opening limitation (9 mm) and history of bilateral condyle fracture...
Oral and Maxillofacial Surgery
Mon Jun 22, 2020 03:00
A Bayesian hierarchical approach to account for left-censored and missing radiation doses prone to classical measurement error when analyzing lung cancer mortality due to γ-ray exposure in the French cohort of uranium miners
Abstract Epidemiological data on cohorts of occupationally exposed uranium miners are currently used to assess health risks associated with chronic exposure to low doses of ionizing radiation. Nevertheless, exposure uncertainty is ubiquitous and questions the validity of statistical inference in these cohorts. This paper highlights the flexibility and relevance of the Bayesian hierarchical approach to account for both missing and left-censored (i.e. only known to be lower than...
Latest Results for Radiation and Environmental Biophysics
Mon Jun 22, 2020 03:00
A clinical dilemma amid COVID-19 pandemic: missed or encountered diagnosis of cancer?
Future Oncology, Ahead of Print.
Future Oncology
Sun Jun 21, 2020 14:54
What is the alternative? Responding strategically to cancer misinformation
Future Oncology, Ahead of Print.
Future Oncology
Sun Jun 21, 2020 14:34
B-cell epitope peptide cancer vaccines: a new paradigm for combination immunotherapies with novel checkpoint peptide vaccine
Future Oncology, Ahead of Print.
Future Oncology
Sun Jun 21, 2020 14:24
The clinical training centers fellowships: a European School of Oncology career development program (2013–2019)
Future Oncology, Ahead of Print.
Future Oncology
Sun Jun 21, 2020 13:20

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