Spinal cord injury (SCI) is involved with abnormal expression of miRNAs (miRs) which are responsible for some IIry injury responses which include apoptosis, inflammation and oxidative stress. Mechanisms involving...
Mon Jun 15, 2020 03:00
Mon Jun 15, 2020 03:00
Hand Hygiene (HH) has been described as the cornerstone and starting point in all infection control. Compliance to HH is a fundamental quality indicator. The aim of this study was to investigate the HH complia...
Mon Jun 15, 2020 03:00
Surgical site infections (SSIs) are common complications after colorectal surgery. Oral non-absorbable antibiotic prophylaxis (OAP) can be administered preoperatively to reduce the risk of SSIs. Its efficacy w...
Mon Jun 15, 2020 03:00
In the present study, we sought to investigate the association between red cell distribution width (RDW) and stroke severity and outcome in patients who underwent anti-thrombolytic therapy with tissue plasmino...
Mon Jun 15, 2020 03:00
Lack of ideal mathematical models to qualify and quantify both pathogenicity, and virulence is a dreadful setback in development of new antimicrobials and vaccines against resistance pathogenic microorganisms....
Mon Jun 15, 2020 03:00
Publication date: Available online 14 June 2020Source: European Journal of Surgical OncologyAuthor(s): Chao Ren, Rui-hua Xu
Mon Jun 15, 2020 19:28
Asian populations tend to have a less projected nasal tip and shorter nose compared to the Caucasian population. Hence, there exists a great demand for augmentation rhinoplasty along with nasal tip plasty in Asia. However, the small and weak nasal septum in the population makes such aesthetic procedures very difficult.1 Septal extension graft (SEG) using harvested septal cartilage is still the standard method for augmenting the tip projection, but the weak L-strut cartilaginous septum often fails...
Mon Jun 15, 2020 03:00
Zusammenfassung Blasen und Erosionen an der Haut und den Schleimhäuten charakterisieren klinisch die heterogene Gruppe der bullösen Autoimmundermatosen (BAID). Diese werden in Pemphigoiderkrankungen mit Autoantikörpern gegen Strukturproteine der dermoepidermalen Junktionszone, Pemphiguserkrankungen mit Autoantikörpern gegen desmosomale Proteine und die Dermatitis herpetiformis Duhring mit Autoantikörpern gegen Transglutaminase 1 und 2 eingeteilt. Eine Unterscheidung der einzelnen...
Mon Jun 15, 2020 03:00
For the first time, a complete time-calibrated phylogeny for a large group of invertebrates is published for an entire continent. Scientists provide a diagrammatic hypothesis of the relationships and evolutionary history for all 496 extant European species of butterflies. Their work provides an important tool for evolutionary and ecological research, meant for the use of insect and ecosystem conservation.
Mon Jun 15, 2020 16:27
בהרצאה תידון השאלה אם יש להתערב בתהליכים המתרחשים בלשון טבעית, או שמא יש להניח לה לנפשה. שאלה זו העסיקה חוקרי לשונות טבעיות, וגם חוקרי העברית עסקו בה בדורות האחרונים. נכיר גישות שונות – גישות טהרניות וגישות מתירניות, ונתאר את גישת האקדמיה ללשון העברית להכוונת הלשון בימינו. המרצה: ד"ר גבריאל בירנבאום, מילא תפקידים בכירים באקדמיה ללשון – הוא היה המזכיר המדעי וחוקר בכיר במפעל המילון ההיסטורי. המחיר: 30 ₪ The post הרצאה מקוונת: עברית נכונה – האם היא קיימת? appeared first on האקדמיה ללשון העברית.
Mon Jun 15, 2020 13:47
סדנת זום לשיפור הטקסט המשפטי על קצה המזלג – 8 שעות אקדמיות ב־4 מפגשים הצטרפו אלינו לסדנה קצרה לדיון על הנושאים האלה: ניסוח טקסט משפטי בהיר, תמציתי וידידותי; תקניות הטקסט – לימוד פרקי ניסוח, כתיב ופיסוק והכרת כלי עבודה. בסדנה נלמד פרקי ניסוח אחדים ונתרגל אותם בטקסטים משפטיים. מנחה: ד"ר אורלי אלבק התאריכים: יום שני, כ"א בתמוז תש"ף (13 ביולי) 18:00 – 19:30 יום רביעי, כ"ג בתמוז תש"ף (15 ביולי) 18:00 – 19:30 יום שני, כ"ח בתמוז תש"ף (20 ביולי) 18:00 – 19:30 יום רביעי, א' באב תש"ף (22 ביולי)...
Mon Jun 15, 2020 13:13
עברי, כתוב עברית! בארכיון שלנו מצאנו מכתב המעיד על דבקותם של אנשים בוועד הלשון בעברית: בקיץ תרצ"ז (1937) התקבל במשרדו של שמואל ייבין, שהיה באותה השעה המזכיר המדעי של ועד הלשון בתל אביב, מכתב בגרמנית מאת ד"ר רודולפינה מנצל, שהייתה ככל הנראה בביקור בארץ ושהתה במקווה ישראל במטרה להכשיר מאלפי כלבים של "ההגנה". ייבין סירב להשיב לפנייה ונימוקו עימו: "לדאבוני הרב רואה אני חובה להחזיר לך את מכתבך מבלי לטפל בו, כי איננו כתוב עברית". ייבין הסביר את החלטתו: "מובטחני, כי אילו היית צריכה לפנות לאיזה מוסד ממשלתי...
Mon Jun 15, 2020 09:13
Purpose: DNA mismatch repair (MMR) deficiency is a hallmark of Lynch syndrome, the most common inherited cancer syndrome. MMR-deficient cancer cells accumulate numerous insertion/deletion mutations at microsatellites. Mutations of coding microsatellites (cMS) lead to the generation of immunogenic frameshift peptide (FSP) neoantigens. As the evolution of MMR-deficient cancers is triggered by mutations inactivating defined cMS-containing tumor suppressor genes, distinct FSP neoantigens are shared by...
Mon Jun 15, 2020 16:11
The potential immune intersection between COVID-19 disease and cancer therapy raises important practical clinical questions and highlights multiple scientific gaps to be filled. Among available therapeutic approaches to consider, checkpoint inhibitors (ICI) seem to require major attention as they may act at the cross-road between cancer treatment and COVID-19 disease, due to their profound immunomodulatory activity. Based on available literature evidences, we suggest guidance to consider for treating...
Mon Jun 15, 2020 16:11
Mon Jun 15, 2020 12:29
Abstract With the emergence of the Novel Coronavirus (2019-nCoV), researchers worldwide have started detecting the probable pathogenesis of the disease. The renin–angiotensin system (RAS) and angiotensin-converting enzymes have received a good deal of attention as possible pathways involved in 2019-nCoV pathogenesis. As the experiments seeking to find potential medications acting on these pathways are being conducted in the early phases, having an ecological worldview on the relationship...
Mon Jun 15, 2020 03:00
Publication date: Available online 15 June 2020Source: Journal of Surgical EducationAuthor(s): Brendan P. Lovasik, Thomas F. Dodson, Keith A. Delman, Jahnavi K. Srinivasan
Mon Jun 15, 2020 17:54
Publication date: Available online 15 June 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Ying Tang, Weina Kong, Jingwen Zhao, Yun Chen, Lei Liu, Guoying Zhang
Mon Jun 15, 2020 17:49
Publication date: Available online 14 June 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Bajram Zeqiri, Lian Wang, Piero Miloro, Stephen P. Robinson
Mon Jun 15, 2020 17:49
Publication date: Available online 14 June 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Franz Josef Putz, Ernst Michael Jung, Christina Putz, Miriam C Banas, Tobias Bergler, Jörg Vienken, Bernhard Banas
Mon Jun 15, 2020 17:49
Publication date: Available online 15 June 2020Source: Auris Nasus LarynxAuthor(s): Mohammad Waheed El-Anwar, Saad Elzayat, Yasser Ahmed Fouad
Mon Jun 15, 2020 17:45
Face-sensitive N170 component of event-related potential is sensitive to face inversion, which has been defined as the face-inversion effect. Moreover, a previous study suggested that similar to the face-inversion effect of the face-sensitive N170 affected by mental rotation of the face, object-related N170 of three-dimensional objects was also affected by the mental rotation of two-dimensional objects. The purpose of the present study was to compare the relationship between face-sensitive N170 during...
Thu Jun 11, 2020 03:00
Publication date: Available online 14 June 2020Source: Autoimmunity ReviewsAuthor(s): Manuel Rubio-Rivas, Catarina Moreira, J. Marcoval
Mon Jun 15, 2020 17:40
Publication date: Available online 14 June 2020Source: Autoimmunity ReviewsAuthor(s): Michael Mahler, Marie Hudson, Chelsea Bentow, Fabrece Roup, Lorenzo Beretta, Carmen Pilar Simeón, Alfredo Guillén-Del-Castillo, Silva Casas, Marvin J. Fritzler
Mon Jun 15, 2020 17:40
Mucosal Immunology, Published online: 15 June 2020; doi:10.1038/s41385-020-0312-8Dietary fiber metabolites regulate innate lymphoid cell responses
Mon Jun 15, 2020 03:00
Nature Communications, Published online: 15 June 2020; doi:10.1038/s41467-020-16788-3Nature Communications encouraged rapid dissemination of results with the launch of Under Consideration in 2017. Today we take one more step by offering an integrated preprint deposition service to our authors as part of the submission process.
Mon Jun 15, 2020 03:00
Nature Communications, Published online: 15 June 2020; doi:10.1038/s41467-020-16826-0Brain ischemia has been associated with deficits in neural oscillations. Here in an animal model, the authors show that modulation of low-gamma oscillations using a light flicker can restore low gamma oscillations and protect ischemic neurons.
Mon Jun 15, 2020 03:00
Nature Communications, Published online: 15 June 2020; doi:10.1038/s41467-020-16828-yB cell development is tightly regulated in a stepwise manner to ensure proper generation of repertoire diversity via somatic gene rearrangements. Here, the authors show that a transcription factor, Erg, functions at the earliest stage to critically control two downstream factors, Ebf1 and Pax5, for modulating this gene rearrangement process.
Mon Jun 15, 2020 03:00
Nature Communications, Published online: 15 June 2020; doi:10.1038/s41467-020-16856-8The human brain can simulate other people’s mental processes with Self-specific and Other-specific neural circuits, but it is not known how these circuits emerge. Here, the authors show that these circuits adapt to social experience, to determine whether a computation is attributed to Self or Other.
Mon Jun 15, 2020 03:00
Nature Communications, Published online: 15 June 2020; doi:10.1038/s41467-020-16842-0The transition between conducting and non-conducting states of K+ channels has been explained by conformational changes at the intracellular entrance to the conduction pathway. Here authors demonstrate that control over K+ currents in Kir channels is not explained by the canonical pore-gating model, as conduction is not impaired by a constricted inner helix bundle.
Mon Jun 15, 2020 03:00
Early stratification of radiotherapy response by activatable inflammation magnetic resonance imaging
Nature Communications, Published online: 15 June 2020; doi:10.1038/s41467-020-16771-yNon-invasive approaches to stratify early responses to therapy are of great value to improve cancer patient management. Here the authors design a hybrid nanovesicle-based activatable inflammation magnetic resonance method for the early prediction of response to radiotherapy.
Mon Jun 15, 2020 03:00
Nature Communications, Published online: 15 June 2020; doi:10.1038/s41467-020-16811-7Earth surface continues to slip after large earthquakes at a slow velocity for a period of a year or more. In this study, the authors show how such slow slip before and after large earthquakes relates to the interaction of the brittle zone of the fault with the ductile zone at greater depth.
Mon Jun 15, 2020 03:00
Nature Communications, Published online: 15 June 2020; doi:10.1038/s41467-020-16677-9Symmetric or asymmetric positioning of intracellular structures such as the nucleus and mitotic spindle steers various biological processes. Here authors use an in vitro model and show that a tug-of-war between centripetal actomyosin waves and percolation of bulk actomyosin network direct the positioning.
Mon Jun 15, 2020 03:00
Nature Communications, Published online: 15 June 2020; doi:10.1038/s41467-020-16529-6The authors develop a first-principles workflow for calculating Raman spectra of 733 monolayers from the computational 2D materials database. After benchmarking results against experimental data for 15 monolayers, an automatic procedure for identifying a material from its Raman spectrum is proposed.
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Early stratification of radiotherapy response by activatable inflammation magnetic resonance imaging
Mon Jun 15, 2020 03:00
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