IJERPH, Vol. 17, Pages 4253: Oral Health Attitudes among Preclinical and Clinical Dental Students in Germany International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17124253 Authors: Mohamed Mekhemar Jonas Conrad Sameh Attia Christof Dörfer Oral health care providers are expected to show good examples of oral health behaviours and attitudes to their community. Previous studies displayed the constructive effect of dental education on oral hygiene...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4268: Impact of the Renin–Angiotensin System on the Endothelium in Vascular Dementia: Unresolved Issues and Future Perspectives International Journal of Molecular Sciences doi: 10.3390/ijms21124268 Authors: Fatima Y. Noureddine Raffaele Altara Fan Fan Andriy Yabluchanskiy George W. Booz Fouad A. Zouein The effects of the renin–angiotensin system (RAS) surpass the renal and cardiovascular systems to encompass other body tissues and organs,...
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IJMS, Vol. 21, Pages 4267: Synthesis of New Star-Shaped Liquid Crystalline Cyclotriphosphazene Derivatives with Fire Retardancy Bearing Amide-Azo and Azo-Azo Linking Units International Journal of Molecular Sciences doi: 10.3390/ijms21124267 Authors: Zuhair Jamain Melati Khairuddean Tay Guan-Seng Two series of new hexasubstituted cyclotriphosphazene derivatives were successfully synthesized and characterized. These derivatives are differentiated by two types of linking units in...
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IJMS, Vol. 21, Pages 4265: Insights about MYC and Apoptosis in B-Lymphomagenesis: An Update from Murine Models International Journal of Molecular Sciences doi: 10.3390/ijms21124265 Authors: Vecchio Fiume Correnti Romano Iaccino Mimmi Maisano Nisticò Quinto The balance between cell survival and cell death represents an essential part of human tissue homeostasis, while altered apoptosis contributes to several pathologies and can affect the treatment efficacy....
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4266: CRISPR Gene Editing of Murine Blood Stem and Progenitor Cells Induces MLL-AF9 Chromosomal Translocation and MLL-AF9 Leukaemogenesis International Journal of Molecular Sciences doi: 10.3390/ijms21124266 Authors: Sarrou Richmond Carmody Gibson Keeshan Chromosomal rearrangements of the mixed lineage leukaemia (MLL, also known as KMT2A) gene on chromosome 11q23 are amongst the most common genetic abnormalities observed in human acute leukaemias....
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4264: Exosomes as Messengers Between Mother and Fetus in Pregnancy International Journal of Molecular Sciences doi: 10.3390/ijms21124264 Authors: Liliana Czernek Markus Düchler The ability of exosomes to transport different molecular cargoes and their ability to influence various physiological factors is already well known. An exciting area of research explores the functions of exosomes in healthy and pathological pregnancies. Placenta-derived exosomes were identified...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4262: Hybrid Materials Based on Silica Matrices Impregnated with Pt-Porphyrin or PtNPs Destined for CO2 Gas Detection or for Wastewaters Color Removal International Journal of Molecular Sciences doi: 10.3390/ijms21124262 Authors: Diana Anghel Anca Lascu Camelia Epuran Ion Fratilescu Catalin Ianasi Mihaela Birdeanu Eugenia Fagadar-Cosma Multifunctional hybrid materials with applications in gas sensing or dye removal from wastewaters were obtained...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4261: Cross-Linked Self-Assembling Peptides and Their Post-Assembly Functionalization via One-Pot and In Situ Gelation System International Journal of Molecular Sciences doi: 10.3390/ijms21124261 Authors: Raffaele Pugliese Fabrizio Gelain Supramolecular nanostructures formed through peptide self-assembly can have a wide range of applications in the biomedical landscape. However, they often lose biomechanical properties at low mechanical stress due to the non-covalent...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4263: Mining for Candidate Genes Controlling Secondary Growth of the Carrot Storage Root International Journal of Molecular Sciences doi: 10.3390/ijms21124263 Authors: Macko-Podgórni Stelmach Kwolek Machaj Ellison Senalik Simon Grzebelus Background: Diverse groups of carrot cultivars have been developed to meet consumer demands and industry needs. Varietal groups of the cultivated carrot are defined based on the shape of roots. However,...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4260: Effectiveness in the Block by Honokiol, a Dimerized Allylphenol from Magnolia Officinalis, of Hyperpolarization-Activated Cation Current and Delayed-Rectifier K+ Current International Journal of Molecular Sciences doi: 10.3390/ijms21124260 Authors: Ming-Huan Chan Hwei-Hsien Chen Yi-Ching Lo Sheng-Nan Wu Background: Honokiol (HNK), a dimer of allylphenol obtained from the bark of Magnolia officinalis was demonstrated to exert an array of biological...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4258: Organophosphorus Compounds and MAPK Signaling Pathways International Journal of Molecular Sciences doi: 10.3390/ijms21124258 Authors: Tahereh Farkhondeh Omid Mehrpour Constanze Buhrmann Ali Mohammad Pourbagher-Shahri Mehdi Shakibaei Saeed Samarghandian The molecular signaling pathways that lead to cell survival/death after exposure to organophosphate compounds (OPCs) are not yet fully understood. Mitogen-activated protein kinases (MAPKs) including...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4259: Oxidative Stress and Thrombosis during Aging: The Roles of Oxidative Stress in RBCs in Venous Thrombosis International Journal of Molecular Sciences doi: 10.3390/ijms21124259 Authors: Qinhong Wang Rahima Zennadi Mid-life stage adults are at higher risk of developing venous thrombosis (VT)/thromboembolism (VT/E). Aging is characterized by an overproduction of reactive oxygen species (ROS), which could evoke a series of physiological changes involved in thrombosis....
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4257: Lipid Mediators Regulate Pulmonary Fibrosis: Potential Mechanisms and Signaling Pathways International Journal of Molecular Sciences doi: 10.3390/ijms21124257 Authors: Vidyani Suryadevara Ramaswamy Ramchandran David W. Kamp Viswanathan Natarajan Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease of unknown etiology characterized by distorted distal lung architecture, inflammation, and fibrosis. The molecular mechanisms involved in the...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4256: Lemon Balm Extract ALS-L1023 Regulates Obesity and Improves Insulin Sensitivity via Activation of Hepatic PPARα in High-Fat Diet-Fed Obese C57BL/6J Mice International Journal of Molecular Sciences doi: 10.3390/ijms21124256 Authors: Dongju Lee Yujin Shin Jong Seong Roh Jiwon Ahn Sunhyo Jeoong Soon Shik Shin Michung Yoon Our previous studies demonstrated that peroxisome proliferator-activated receptor α (PPARα) activation...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4255: Extracellular Vesicles: A Therapeutic Option for Liver Fibrosis International Journal of Molecular Sciences doi: 10.3390/ijms21124255 Authors: Stefania Bruno Giulia Chiabotto Giovanni Camussi Extracellular vesicles (EVs) are a heterogeneous population of small membrane vesicles released by all types of cells in both physiological and pathological conditions. EVs shuttle different types of molecules and are able to modify the behavior of target cells by...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4252: Micro-Transcriptome Analysis Reveals Immune-Related MicroRNA Regulatory Networks of Paralichthys olivaceus Induced by Vibrio anguillarum Infection International Journal of Molecular Sciences doi: 10.3390/ijms21124252 Authors: Xianhui Ning Li Sun MicroRNAs (miRNAs) are non-coding regulatory RNAs that play a vital part in the host immune response to pathogen infection. Japanese flounder (Paralichthys olivaceus) is an important aquaculture fish species that...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4253: Chiral Ionic Liquids: Structural Diversity, Properties and Applications in Selected Separation Techniques International Journal of Molecular Sciences doi: 10.3390/ijms21124253 Authors: Jolanta Flieger Joanna Feder-Kubis Małgorzata Tatarczak-Michalewska Ionic liquids (ILs) are chemical compounds composed of ions with melting points below 100 °C exhibiting a design feature. ILs are commonly used as the so-called green solvents, reagents or highly...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4254: Interplay Between SNX27 and DAG Metabolism in the Control of Trafficking and Signaling at the IS International Journal of Molecular Sciences doi: 10.3390/ijms21124254 Authors: Natalia González-Mancha Isabel Mérida Recognition of antigens displayed on the surface of an antigen-presenting cell (APC) by T-cell receptors (TCR) of a T lymphocyte leads to the formation of a specialized contact between both cells named the immune synapse (IS). This highly organized...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4251: A Synthetic Cell-Penetrating Heparin-Binding Peptide Derived from BMP4 with Anti-Inflammatory and Chondrogenic Functions for the Treatment of Arthritis International Journal of Molecular Sciences doi: 10.3390/ijms21124251 Authors: Da Hyeon Choi Dongwoo Lee Beom Soo Jo Kwang-Sook Park Kyeong Eun Lee Ju Kwang Choi Yoon Jeong Park Jue-Yeon Lee Yoon Shin Park We report dual therapeutic effects of a synthetic heparin-binding peptide (HBP)...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4250: Editorial for the Special Issue “Animal Models of Parkinson’s Disease and Related Disorders” International Journal of Molecular Sciences doi: 10.3390/ijms21124250 Authors: Yuzuru Imai Parkinson’s disease (PD) is the second most common neurodegenerative disorder characterized by age-dependent motor dysfunction and degeneration of the midbrain dopaminergic neurons [...]
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4249: Generation of Hematopoietic-Like Stem Cells from Adult Human Peripheral Blood Following Treatment with Platelet-Derived Mitochondria International Journal of Molecular Sciences doi: 10.3390/ijms21124249 Authors: Haibo Yu Wei Hu Xiang Song Dante Descalzi-Montoya Zheng Yang Robert Korngold Yong Zhao Adult stem cells represent a potential source for cellular therapy to treat serious human diseases. We characterized the insulin-producing cells...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4248: The Heterooligomerization of Human Small Heat Shock Proteins Is Controlled by Conserved Motif Located in the N-Terminal Domain International Journal of Molecular Sciences doi: 10.3390/ijms21124248 Authors: Vladislav M. Shatov Sergei V. Strelkov Nikolai B. Gusev Ubiquitously expressed human small heat shock proteins (sHsps) HspB1, HspB5, HspB6 and HspB8 contain a conserved motif (S/G)RLFD in their N-terminal domain. For each of them, we prepared mutants...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4247: Regulation of Autophagy by Protein Kinase C-ε in Breast Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms21124247 Authors: Alakananda Basu Protein kinase C-ε (PKCε), an anti-apoptotic protein, plays critical roles in breast cancer development and progression. Although autophagy is an important survival mechanism, it is not known if PKCε regulates autophagy in breast cancer cells. We have shown that...
Mon Jun 15, 2020 03:00
IJMS, Vol. 21, Pages 4246: First Report of the Potential Bovine Spongiform Encephalopathy (BSE)-Related Somatic Mutation E211K of the Prion Protein Gene (PRNP) in Cattle International Journal of Molecular Sciences doi: 10.3390/ijms21124246 Authors: Sae-Young Won Yong-Chan Kim Byung-Hoon Jeong Bovine spongiform encephalopathy (BSE) is a prion disease characterized by spongiform degeneration and astrocytosis in the brain. Unlike classical BSE, which is caused by prion-disease-contaminated...
Mon Jun 15, 2020 03:00
JCM, Vol. 9, Pages 1870: Non-Small Cell Lung Cancer from Genomics to Therapeutics: A Framework for Community Practice Integration to Arrive at Personalized Therapy Strategies Journal of Clinical Medicine doi: 10.3390/jcm9061870 Authors: Swapnil Rajurkar Isa Mambetsariev Rebecca Pharaon Benjamin Leach TingTing Tan Prakash Kulkarni Ravi Salgia Non-small cell lung cancer (NSCLC) is a heterogeneous disease, and therapeutic management has advanced with the identification...
Mon Jun 15, 2020 03:00
JCM, Vol. 9, Pages 1869: Impact of Acute Hemoglobin Falls in Heart Failure Patients: A Population Study Journal of Clinical Medicine doi: 10.3390/jcm9061869 Authors: Cristina Lopez Jose Luis Holgado Antonio Fernandez Inmaculada Sauri Ruth Uso Jose Luis Trillo Sara Vela Carlos Bea Julio Nuñez Ana Ferrer Javier Gamez Adrian Ruiz Josep Redon Aims: This study assessed the impact of acute hemoglobin (Hb) falls in heart failure (HF) patients. Methods: HF...
Mon Jun 15, 2020 03:00
JCM, Vol. 9, Pages 1867: A Pharmacovigilance Study of Hydroxychloroquine Cardiac Safety Profile: Potential Implication in COVID-19 Mitigation Journal of Clinical Medicine doi: 10.3390/jcm9061867 Authors: Anand Prakash Singh Sultan Tousif Prachi Umbarkar Hind Lal In light of the favorable outcomes of few small, non-randomized clinical studies, the Food and Drug Administration (FDA) has issued an Emergency Use Authorization (EUA) to Hydroxychloroquine (HCQ) for hospitalized coronavirus...
Mon Jun 15, 2020 03:00
JCM, Vol. 9, Pages 1866: Genetic Variants as Sudden-Death Risk Markers in Inherited Arrhythmogenic Syndromes: Personalized Genetic Interpretation Journal of Clinical Medicine doi: 10.3390/jcm9061866 Authors: Oscar Campuzano Georgia Sarquella-Brugada Elena Arbelo Sergi Cesar Paloma Jordà Alexandra Pérez-Serra Rocío Toro Josep Brugada Ramon Brugada Inherited arrhythmogenic syndromes are the primary cause of unexpected lethal cardiac episodes in young people. It...
Mon Jun 15, 2020 03:00
JCM, Vol. 9, Pages 1868: Reorganization Tips from a Sarcoma Unit at Time of the COVID-19 Pandemic in Italy: Early Experience from a Regional Referral Oncologic Center Journal of Clinical Medicine doi: 10.3390/jcm9061868 Authors: Barbara Rossi Carmine Zoccali Jacopo Baldi Alessandra Scotto di Uccio Roberto Biagini Assunta De Luca Maria Grazia Petrongari Virginia Ferraresi Since the World Health Organization declared the novel coronavirus outbreak a global health...
Mon Jun 15, 2020 03:00
JCM, Vol. 9, Pages 1864: Tryptophan Metabolism via the Kynurenine Pathway: Implications for Graft Optimization during Machine Perfusion Journal of Clinical Medicine doi: 10.3390/jcm9061864 Authors: Anna Zhang Cailah Carroll Siavash Raigani Negin Karimian Viola Huang Sonal Nagpal Irene Beijert Robert J. Porte Martin Yarmush Korkut Uygun Heidi Yeh Access to liver transplantation continues to be hindered by the severe organ shortage. Extended-criteria donor...
Mon Jun 15, 2020 03:00
JCM, Vol. 9, Pages 1863: Long-Term Visual/Anatomic Outcome in Patients with Fovea-Involving Fibrovascular Pigment Epithelium Detachment Presenting Choroidal Neovascularization on Optical Coherence Tomography Angiography Journal of Clinical Medicine doi: 10.3390/jcm9061863 Authors: Kyung Tae Kim Hwanho Lee Jin Young Kim Suhwan Lee Ju Byung Chae Dong Yoon Kim Background: To evaluate long-term visual/anatomic outcome after anti-vascular endothelial growth factor (anti-VEGF)...
Mon Jun 15, 2020 03:00
JCM, Vol. 9, Pages 1865: Comparison of Male and Female Patients in Louisiana Medical Marijuana Dispensaries Journal of Clinical Medicine doi: 10.3390/jcm9061865 Authors: H. Raymond Allen Doug Boudreaux Jeffrey N. Keller Relatively little is known in terms of patient demographics, indications, previous cannabis use, or the forms and dosages of medical marijuana (MM) dispensed for patients at MM dispensaries. Even less is known in terms of how male and female patients may differ...
Mon Jun 15, 2020 03:00
JCM, Vol. 9, Pages 1862: Endotheliitis and Endothelial Dysfunction in Patients with COVID-19: Its Role in Thrombosis and Adverse Outcomes Journal of Clinical Medicine doi: 10.3390/jcm9061862 Authors: Wassim Mosleh Kai Chen Steven E. Pfau Aseem Vashist Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV2), emerging in Wuhan, China and developing into a pandemic with rapidly emerging cardiovascular manifestations...
Mon Jun 15, 2020 03:00
JCM, Vol. 9, Pages 1861: Spectrum and Frequency of Tumors, Cancer Risk and Survival in Chilean Families with Lynch Syndrome: Experience of the Implementation of a Registry Journal of Clinical Medicine doi: 10.3390/jcm9061861 Authors: Karin Álvarez Paulina Orellana Marjorie De la Fuente Tamara Canales Eliana Pinto Claudio Heine Benjamín Solar Claudia Hurtado Pål Møller Udo Kronberg Alejandro José Zarate Mev Dominguez-Valentin Francisco López-Köstner Lynch...
Mon Jun 15, 2020 03:00
JCM, Vol. 9, Pages 1860: Medical Treatment of Advanced Pancreatic Neuroendocrine Neoplasms Journal of Clinical Medicine doi: 10.3390/jcm9061860 Authors: Lola-Jade Palmieri Solène Dermine Amélie Barré Marion Dhooge Catherine Brezault Anne-Ségolène Cottereau Romain Coriat Pancreatic neuroendocrine neoplasms (panNENs) are relatively rare but their incidence has increased almost sevenfold over the last four decades. Neuroendocrine neoplasms are classified according to their...
Mon Jun 15, 2020 03:00
JCM, Vol. 9, Pages 1859: Come in from the Cold: Are Older Adults Who Live in Colder Climates at Greater Risk for Sarcopenia? Journal of Clinical Medicine doi: 10.3390/jcm9061859 Authors: David Scott The operational definition of “sarcopenia”, an age-related skeletal muscle disease resulting from adverse changes that accrue across the lifetime, was recently updated by the European Working Group on Sarcopenia in Older People (EWGSOP) [...]
Mon Jun 15, 2020 03:00
JFMK, Vol. 5, Pages 43: Associations between Activity Pacing, Fatigue, and Physical Activity in Adults with Multiple Sclerosis: A Cross Sectional Study Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5020043 Authors: Ulric S. Abonie Femke Hoekstra Bregje L. Seves Lucas H. V. van der Woude Rienk Dekker Florentina J. Hettinga Fatigue is common in people with multiple sclerosis (MS). Activity pacing is a behavioral way to cope with fatigue and limited energy...
Mon Jun 15, 2020 03:00
JPM, Vol. 10, Pages 51: Risk Factors Associated with Low Back Pain among A Group of 1510 Pregnant Women Journal of Personalized Medicine doi: 10.3390/jpm10020051 Authors: Aleksandra Bryndal Marian Majchrzycki Agnieszka Grochulska Sebastian Glowinski Agnieszka Seremak-Mrozikiewicz Background: Low Back Pain (LBP) is a frequent, very common, and costly health problem. LBP, which occurs during pregnancy, may become a lifelong problem. The aim of this study was to determine the...
Mon Jun 15, 2020 03:00
JPM, Vol. 10, Pages 50: An Omics View of Emery–Dreifuss Muscular Dystrophy Journal of Personalized Medicine doi: 10.3390/jpm10020050 Authors: Nicolas Vignier Antoine Muchir Recent progress in Omics technologies has started to empower personalized healthcare development at a thorough biomolecular level. Omics have subsidized medical breakthroughs that have started to enter clinical proceedings. The use of this scientific know-how has surfaced as a way to provide a more far-reaching...
Mon Jun 15, 2020 03:00
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