Related ArticlesClinical significance of tumour mutation burden in immunotherapy across multiple cancer types: an individual meta-analysis. Jpn J Clin Oncol. 2020 Jun 16;: Authors: Yang Z, Wei S, Deng Y, Wang Z, Liu L Abstract BACKGROUND: Biomarkers for stratifying patients that could benefit from immune checkpoint inhibitors are necessary. Tumour mutation burden has recently become a promising biomarker in cancer, but the associations between tumour...
Wed Jun 17, 2020 14:38
Related ArticlesStereotactic body radiotherapy in patients with early-stage non-small cell lung cancer: Does beam-on time matter? Jpn J Clin Oncol. 2020 Jun 16;: Authors: Hurmuz P, Cengiz M, Ozyigit G, Akkas EA, Yuce D, Yilmaz MT, Yildiz D, Zorlu F, Akyol F Abstract PURPOSE: Stereotactic body radiotherapy (SBRT) is an effective treatment option for patients with early-stage non-small cell lung cancer (NSCLC). In this study, we evaluated the treatment...
Wed Jun 17, 2020 14:38
Related ArticlesDoes the right or left hemisphere involvement affect the swallowing in patients with hemiplegia? NeuroRehabilitation. 2020 Jun 12;: Authors: Sayaca C, Sapcíoglu TY, Kaya D Abstract BACKGROUND: Stroke is one of the most important causes of swallowing difficulty. It is seen in one of every two patients with stroke. Although swallowing function are controlled by both hemispheres, it is unknown which hemisphere is more dominant than another...
Wed Jun 17, 2020 13:38
Related ArticlesBlood flow restriction training: you can occlude your veins, but not your oxygen transport. J Physiol. 2020 Jun 15;: Authors: Kambič T PMID: 32539161 [PubMed - as supplied by publisher]
Wed Jun 17, 2020 13:29
Related ArticlesMaternal exercise attenuates the lower skeletal muscle glucose uptake and insulin secretion caused by paternal obesity in female adult rat offspring. J Physiol. 2020 Jun 15;: Authors: Falcão-Tebas F, Marin EC, Kuang J, Bishop DJ, McConell GK Abstract KEY POINTS: Paternal obesity negatively influences the metabolic outcomes in adult rat offspring. Maternal voluntary physical activity has previously been reported to improve glucose metabolism...
Wed Jun 17, 2020 13:29
Related ArticlesDrp1 knockdown induces severe muscle atrophy and remodelling, mitochondrial dysfunction, autophagy impairment and denervation. J Physiol. 2020 Jun 15;: Authors: Dulac M, Leduc-Gaudet JP, Reynaud O, Ayoub MB, Guérin A, Finkelchtein M, Hussain SN, Gouspillou G Abstract KEY POINTS: The maintenance of optimal mitochondrial content and function is critical for muscle health. Mitochondrial dynamics play key roles in mitochondrial quality control,...
Wed Jun 17, 2020 13:29
Related ArticlesIncreasing excitation vs. decreasing inhibition in auditory cortex: Consequences on the discrimination performance between communication sounds. J Physiol. 2020 Jun 15;: Authors: Gaucher Q, Yger P, Edeline JM Abstract KEY POINTS: Enhancing cortical excitability can be achieved by either reducing intracortical inhibition or by enhancing intracortical excitation. Here we compare the consequences of reducing the intracortical inhibition...
Wed Jun 17, 2020 13:29
Related ArticlesIn-vivo recordings from the human vagus nerve using ultrasound-guided microneurography. J Physiol. 2020 Jun 15;: Authors: Ottaviani MM, Wright L, Dawood T, Macefield VG Abstract KEY POINTS: The vagus nerve is the largest cranial nerve and innervates many structures in the neck, thorax and abdomen While single-unit recordings from the vagus nerve have been performed in experimental animals for seven decades, no recordings have ever been...
Wed Jun 17, 2020 13:29
Related ArticlesCorrigendum. J Physiol. 2020 Jun;598(12):2507 Authors: PMID: 32537775 [PubMed - in process]
Wed Jun 17, 2020 13:29
Related ArticlesEffect of acute nitrite infusion on contractile economy and metabolism in isolated skeletal muscle in situ during hypoxia. J Physiol. 2020 Jun;598(12):2371-2384 Authors: Porcelli S, Rasica L, Ferguson BS, Kavazis AN, McDonald J, Hogan MC, Grassi B, Gladden LB Abstract KEY POINTS: Increased plasma nitrite concentrations may have beneficial effects on skeletal muscle function. The physiological basis explaining these observations has not...
Wed Jun 17, 2020 13:29
Related ArticlesTime of day dependent effects of contractile activity on the phase of the skeletal muscle clock. J Physiol. 2020 Jun 14;: Authors: Kemler D, Wolff CA, Esser KA Abstract KEY POINTS: Disruptions in circadian rhythms across an organism are associated with negative health outcomes, such as cardiometabolic and neurodegenerative diseases. Exercise has been proposed as a time cue for the circadian clock in rodents and humans In this study, we...
Wed Jun 17, 2020 13:29
Related ArticlesPolypoid endometriosis of the rectum and vagina in an adolescent. J Pediatr Adolesc Gynecol. 2020 Jun 13;: Authors: Ling R, Jin H, Yang Y, Cheng L Abstract BACKGROUND: Polypoid endometriosis (PEM) is a rare type of endometriosis, frequently mimicking a malignant tumor. We reported a 10-year span case of PEM who had symptoms at age 16. CASE: A 20-year-old woman presented with massive vaginal hemorrhage and spontaneous abortion,...
Wed Jun 17, 2020 14:32
Related ArticlesComparative genomics of high grade neuroendocrine carcinoma of the cervix. PLoS One. 2020;15(6):e0234505 Authors: Hillman RT, Cardnell R, Fujimoto J, Lee WC, Zhang J, Byers LA, Ramalingam P, Leitao M, Swisher E, Futreal PA, Frumovitz M Abstract In order to improve treatment selection for high grade neuroendocrine carcinomas of the cervix (NECC), we performed a comparative genomic analysis between this rare tumor type and other cervical...
Wed Jun 17, 2020 14:32
Related ArticlesWunderlich syndrome secondary to cyst rupture and concurrent anticoagulation. Can J Urol. 2020 Jun;27(3):10270-10272 Authors: Gurbani CM, Khor V, Leow JJ, Tay MHW, Chong YL Abstract Wunderlich syndrome (WS) is a rare triad of flank pain, flank mass and hypovolemic shock and is classically attributed to angiomyolipomata or neoplasms. Treatment is guided by clinical severity: conservative, selective arterial embolization, or nephrectomy....
Wed Jun 17, 2020 14:32
Related ArticlesChronic active Epstein-Barr virus infection: A heterogeneous entity requiring a high index of suspicion for diagnosis. Int J Lab Hematol. 2020 Jun;42 Suppl 1:99-106 Authors: Ondrejka SL, Hsi ED Abstract Chronic active Epstein-Barr virus infection of T- and NK-cell type, systemic form, is a rare entity within the spectrum of EBV-driven T- and NK-cell lymphoproliferative disorders. Established diagnostic criteria and a characteristic clinical...
Wed Jun 17, 2020 14:32
Related ArticlesPrimary Rectal Amelanotic Malignant Melanoma: A Rare Case Report. Cureus. 2020 May 14;12(5):e8115 Authors: Nafees R, Khan H, Ahmed S, Ahmed Samo K, Siraj Memon A Abstract Malignant melanoma of the rectum comprises 0.5%-4% of all anorectal cancers. Malignant melanoma of the rectum is exceptionally a rare disease. It commonly affects the fifth or sixth decade, with nonspecific symptoms such as rectal bleeding or anal pain. After skin and...
Wed Jun 17, 2020 14:32
Related ArticlesA Randomized Phase IIa Trial with Temsirolimus versus Sunitinib in Advanced Non-Clear Cell Renal Cell Carcinoma: An Intergroup Study of the CESAR Central European Society for Anticancer Drug Research-EWIV and the Interdisciplinary Working Group on Renal Cell Cancer (IAGN) of the German Cancer Society. Oncol Res Treat. 2020 Jun 15;:1-6 Authors: Bergmann L, Grünwald V, Maute L, Grimm MO, Weikert S, Schleicher J, Klotz T, Greiner J, Flörcken A, Hartmann A,...
Wed Jun 17, 2020 14:32
Related ArticlesImaging and Contrast-enhanced Ultrasound features of duodenal neuroendocrine tumor: A case report. Clin Hemorheol Microcirc. 2020 Jun 06;: Authors: Zhang YQ, Wen JX, Luo RK, Yuan HX, Wang WP Abstract Duodenal neuroendocrine tumors are rare neoplasms arising from endocrine cells. Here we present a case of 32-year-old woman with Duodenal neuroendocrine tumors, report the imaging and contrast-enhanced Ultrasound (CEUS) features and review...
Wed Jun 17, 2020 13:28
Related ArticlesIntermixed medullary and papillary thyroid cancer in a patient with renal cell carcinoma. Endocrinol Diabetes Metab Case Rep. 2020 Jun 04;2020: Authors: Samarasinghe S, Yuksel S, Mehrotra S Abstract Summary: We report a rare case of concurrent medullary thyroid cancer (MTC) and papillary thyroid cancer (PTC) with intermixed disease in several of the lymph node (LN) metastases in a patient who was subsequently diagnosed with clear cell...
Wed Jun 17, 2020 13:28
Related ArticlesCan Epstein-Barr virus play a role in upper urinary tract urothelial carcinomas? Ann R Coll Surg Engl. 2020 Jun 15;:1-5 Authors: Dere Y, Ekmekçi S, Akarken I, Küçük Ü Abstract INTRODUCTION: Upper urinary tract urothelial carcinomas are very rare tumours with different biological behaviours. The Epstein-Barr virus, which is the first known oncogenic virus, is being investigated for various malignant tumours. It is known that this virus...
Wed Jun 17, 2020 13:28
Related ArticlesA Rare Case of Essential Thrombocythemia with Coexisting JAK2 and MPL Driver Mutations. J Korean Med Sci. 2020 Jun 15;35(23):e168 Authors: Jang MA, Seo MY, Choi KJ, Hong DS Abstract Philadelphia-negative (Ph-) classical myeloproliferative neoplasms (MPNs) include polycythemia vera, essential thrombocythemia (ET), and primary myelofibrosis. Somatic driver mutations in the JAK2, CALR, and MPL genes serve as major diagnostic criteria of...
Wed Jun 17, 2020 13:28
Related ArticlesA Bayesian approach in design and analysis of pediatric cancer clinical trials. Pharm Stat. 2020 Jun 14;: Authors: Ye J, Reaman G, De Claro RA, Sridhara R Abstract It is well recognized that cancer drug development for children and adolescents has many challenges, from biological and societal to economic. Pediatric cancer consists of a diverse group of rare diseases, and the relatively small population of children with multiple, disparate...
Wed Jun 17, 2020 13:28
Related ArticlesCurrent status and perspectives of patient-derived rare cancer models. Hum Cell. 2020 Jun 14;: Authors: Kondo T Abstract Malignancies with extremely low incidences, such as less than 6 per 100,000 people annually, are defined as rare cancers. Approximately 200 malignancies are classified in this category, therefore the total number of patients with rare cancers is greater than that of patients with any single common cancer. However, because...
Wed Jun 17, 2020 13:28
Related ArticlesBiomarkers for Pancreatic Neuroendocrine Neoplasms (PanNENs) Management-An Updated Review. Front Oncol. 2020;10:831 Authors: Bocchini M, Nicolini F, Severi S, Bongiovanni A, Ibrahim T, Simonetti G, Grassi I, Mazza M Abstract Pancreatic neuroendocrine tumors (PanNENs) are rare sporadic cancers or develop as part of hereditary syndromes. PanNENs can be both functioning and non-functioning based on whether they produce bioactive peptides....
Wed Jun 17, 2020 13:28
Related ArticlesRelative survival after diagnosis with a primary brain or other central nervous system tumor in the National Program of Cancer Registries, 2004 to 2014. Neurooncol Pract. 2020 Jun;7(3):306-312 Authors: Ostrom QT, Truitt G, Gittleman H, Brat DJ, Kruchko C, Wilson R, Barnholtz-Sloan JS Abstract Background: The majority of reported cancer survival statistics in the United States are generated using the National Cancer Institute's publicly...
Wed Jun 17, 2020 13:28
Related Articles[Rare association between maternal ovarian cancer and neonatal brain tumor: about a case]. Pan Afr Med J. 2020;35:75 Authors: Rhalem H, Knouni H, Barkat A Abstract Fetal brain tumors are rare. Teratoma is the most common histological type. Their evolution is often fatal. Ultrasound and magnetic resonance imaging allows for early antenatal diagnosis. However, definitive diagnosis is based on histologic examination. Placental metastases...
Wed Jun 17, 2020 13:28
Related ArticlesPrimary pancreatic Ewing sarcoma: a cytomorphologic and histopathologic study of 13 cases. J Am Soc Cytopathol. 2020 May 12;: Authors: Miller DL, Roy-Chowdhuri S, Illei P, James A, Hruban RH, Ali SZ Abstract INTRODUCTION: Ewing sarcoma (ES) is a small, round cell sarcoma that rarely occurs in solid organs, including the pancreas. A diagnostic overlap exists with other primary pancreatic neoplasms, especially for specimens from small biopsies...
Wed Jun 17, 2020 13:28
Related ArticlesOffice-Based Percutaneous Fasciotomy for Dupuytren Contracture. Orthop Clin North Am. 2020 Jul;51(3):369-372 Authors: Chambers J, Pate T, Calandruccio J Abstract Percutaneous fasciotomy is a safe, simple, and inexpensive treatment for mild to moderate Dupuytren contracture. The decrease in extension deficit in the metacarpophalangeal and proximal interphalangeal joints after release correlates with improvement in patient-reported outcomes....
Wed Jun 17, 2020 13:28
Related ArticlesAcromegaly: 'You must know it to think of it'. Eur J Endocrinol. 2020 Jul;183(1):C1-C4 Authors: Boguszewski CL Abstract Acromegaly is a debilitating and disfiguring chronic disease, which occurs in both sexes at any age, associated with multiple comorbidities and increased mortality. It is typically caused by a GH-secreting pituitary adenoma that promotes exposure of body tissues to increased concentrations of GH and IGF-I. The diagnosis...
Wed Jun 17, 2020 13:28
Related ArticlesGastric adenocarcinoma of the fundic gland type: A case report. Medicine (Baltimore). 2020 May 22;99(21):e20361 Authors: Fan X, Yang XS, Bai P, Ren YB, Zhang L, Li X, Wang L, Wang Y, Ding YM, Zeng RR, Lin XC Abstract INTRODUCTION: Gastric adenocarcinoma of the fundic gland type (GA-FG) is a newly described entity that is characterized by well-differentiated neoplasm with unclear etiopathogenesis. PATIENT CONCERNS: A 60-year-old...
Wed Jun 17, 2020 13:28
Related ArticlesAnalysis of magnetic resonance imaging features of ovarian thecoma. Medicine (Baltimore). 2020 May 22;99(21):e20358 Authors: Li Z, Hu Q, Luo Z, Deng Z, Zhou W, Xie L Abstract To investigate the magnetic resonance imaging (MRI) findings in ovarian thecoma and improve preoperative diagnostic accuracy.Retrospective analysis was performed on 45 patients with surgically and pathologically confirmed ovarian thecoma. Patients were grouped...
Wed Jun 17, 2020 13:28
Related ArticlesEchinococcosis with the image of peritoneal carcinomatosis. Ceska Gynekol. 2020;85(1):35-40 Authors: Gazurová Z, Kaščák P Abstract OBJECTIVE: Describe the case of echinococcal disease in gynecological practice and point out the complications of its diagnosis. DESIGN: Case report. SETTING: Department of Obstetrics and Gynaecology, Faculty Hospital Trenčín, Slovakia. CASE REPORT: The case is presented in an immunosuppressed...
Wed Jun 17, 2020 13:28
Related ArticlesPolymethoxyflavones from Gardenia oudiepe (Rubiaceae) induce cytoskeleton disruption-mediated apoptosis and sensitize BRAF-mutated melanoma cells to chemotherapy. Chem Biol Interact. 2020 Jul 01;325:109109 Authors: Gonçalves de Oliveira-Júnior R, Marcoult-Fréville N, Prunier G, Beaugeard L, Beserra de Alencar Filho E, Simões Mourão ED, Michel S, Quintans-Júnior LJ, Guedes da Silva Almeida JR, Grougnet R, Picot L Abstract A series of...
Wed Jun 17, 2020 13:28
Related ArticlesBrain metastases from germ cell tumor: time to reconsider radiotherapy? Crit Rev Oncol Hematol. 2020 Jun;150:102946 Authors: Khalifa J, Fléchon A, Chevreau C Abstract The presence of brain metastases (BMs) from germ cell tumor (GCT) remains a rare situation. BMs predominantly occur among patients with testis primary tumor site, and are almost exclusively associated with non-seminomatous (NS) histologies. Two situations must be distinguished,...
Wed Jun 17, 2020 13:28
Related ArticlesOlaparib and temozolomide in desmoplastic small round cell tumors: a promising combination in vitro and in vivo. J Cancer Res Clin Oncol. 2020 Jul;146(7):1659-1670 Authors: van Erp AEM, van Houdt L, Hillebrandt-Roeffen MHS, van Bree NFHN, Flucke UE, Mentzel T, Shipley J, Desar IME, Fleuren EDG, Versleijen-Jonkers YMH, van der Graaf WTA Abstract PURPOSE: Desmoplastic small round cell tumors (DSRCTs) are highly malignant and very rare...
Wed Jun 17, 2020 13:28
Related Articles[A woman with a red, painful breast]. Ned Tijdschr Geneeskd. 2019 12 05;163: Authors: Romeijn MM, Nielsen K, Schreurs WH Abstract A 79-year-old woman presented with swelling and pain in her right breast after re-excision of a melanoma and an axillary sentinel lymph node biopsy. The cellulitis was caused by Clostridium perfringens, a rare cause of a postoperative infection.PMID: 32073787 [PubMed - indexed for MEDLINE]
Wed Jun 17, 2020 13:28
Related ArticlesClinicopathologic features of undifferentiated round cell sarcomas of bone & soft tissues: An attempt to unravel the BCOR-CCNB3- & CIC-DUX4-positive sarcomas. Indian J Med Res. 2019 12;150(6):557-574 Authors: Rekhi B, Kembhavi P, Mishra SN, Shetty O, Bajpai J, Puri A Abstract Background & objectives: Certain genetically defined undifferentiated round cell sarcomas, namely BCOR-CCNB3 and CIC-DUX4 positive, have been described....
Wed Jun 17, 2020 13:28
Related ArticlesLaparoscopic spleen-preserving distal pancreatectomy for a solid-cystic intraabdominal desmoid tumor at a gastro-pancreatic lesion: a case report. BMC Surg. 2020 Feb 03;20(1):24 Authors: Sugimachi K, Iguchi T, Ohta M, Mano Y, Hisano T, Yokoyama R, Taguchi K, Ikebe M, Morita M, Toh Y Abstract BACKGROUND: We report a case of an intraabdominal desmoid tumor that occurred at a gastro-pancreatic lesion with spontaneous cystic features, and...
Wed Jun 17, 2020 13:28
Related ArticlesPancreatic abscess within hepato-gastric ligament: case report of an extremely rare disease. BMC Surg. 2020 Jan 30;20(1):20 Authors: Bakshi S Abstract BACKGROUND: Pancreatic pseudocyst is a very common benign cystic lesion of the pancreas. It develops in 5-15% of patients with peri-pancreatic fluid collection following acute pancreatitis. Collection usually occurs within the lesser sac of the omentum (near the pancreatic head and body...
Wed Jun 17, 2020 13:28
Related ArticlesSimultaneous occurrence of invasive pulmonary aspergillosis and diffuse large B-cell lymphoma: case report and literature review. BMC Cancer. 2020 Jan 06;20(1):15 Authors: Shao L, Jiang L, Wu S, Yu L, Wang L, Huang X Abstract BACKGROUND: Patients with lymphoma are at risk for developing pulmonary opportunistic infections due to immunocompromise. However, clinical reports of concurrent lymphoma and opportunistic infection at presentation...
Wed Jun 17, 2020 13:28
Related ArticlesFast growing angiosarcoma of the right atrium after radiofrequency catheter ablation: a missed diagnosis or misdiagnosis case report. BMC Cancer. 2020 Jan 06;20(1):13 Authors: Yu Y, Wang Q, Sun J, Zhao J, Chen S, Li Y Abstract BACKGROUND: Primary angiosarcomas of the right atrium are extremely rare, often resulted in missed diagnosis or misdiagnosis with routine examination tools. These malignant cardiac tumors are highly aggressive...
Wed Jun 17, 2020 13:28
Related ArticlesAbscopal effect in lung cancer: three case reports and a concise review. Immunotherapy. 2019 12;11(17):1445-1461 Authors: Garelli E, Rittmeyer A, Putora PM, Glatzer M, Dressel R, Andreas S Abstract The abscopal effect describes the ability of locally administered radiotherapy to induce systemic antitumor effects. Over the past 40 years, reports on the abscopal effect following conventional radiation have been relatively rare, especially...
Wed Jun 17, 2020 13:28
Related ArticlesCharacterization of 22 Canine Pancreatic Carcinomas and Review of Literature. J Comp Pathol. 2019 Nov;173:71-82 Authors: Aupperle-Lellbach H, Törner K, Staudacher M, Müller E, Steiger K, Klopfleisch R Abstract Pancreatic carcinomas are rare in dogs and clinical signs are mostly non-specific. The literature on clinically and pathologically characterized canine exocrine pancreatic tumours is limited to 76 cases reported since 1963. This...
Wed Jun 17, 2020 13:28
Related ArticlesCase Report: Borderline tumor and primary peritoneal carcinoma - a rare synchronism. F1000Res. 2019;8:1630 Authors: Rei M, Raposo S, Figueiredo P, Sousa R, Sá L Abstract Ovarian borderline serous tumors present with peritoneal involvement in 20% of cases, either as non-invasive or invasive implants, the latter also known as extraovarian low-grade serous carcinoma. The coexistence of high-grade serous carcinoma is rare, suggesting a...
Wed Jun 17, 2020 13:28
Related ArticlesPrognosis of early stage small cell bladder cancer is not always dismal. ESMO Open. 2019;4(6):e000559 Authors: Lim JH, Sundar S Abstract Background: Small cell carcinoma of the urinary bladder (SCCB) is an extremely rare malignancy which is often associated with poor survival outcome. Literature reporting such disease is scarce. There is no standardised management. This retrospective audit examines a UK Cancer Centre's SCCB management...
Wed Jun 17, 2020 13:28
Related ArticlesAdrenal insufficiency due to recurrent renal cell carcinoma in the left adrenal gland 3 years after right radical nephrectomy for renal cell carcinoma. Postgrad Med. 2020 Apr;132(3):301-303 Authors: Lee MW, Lee HJ Abstract Primary adrenal insufficiency due to tumor involvement is very rare. We herein report a case of adrenal insufficiency caused by cancer metastasis to a remaining single adrenal gland in a renal cell carcinoma patient...
Wed Jun 17, 2020 13:28
Related ArticlesA case report: a giant cardiac atypical lipoma associated with pericardium and right atrium. BMC Cardiovasc Disord. 2019 11 06;19(1):247 Authors: Wang X, Yu X, Ren W, Li D Abstract BACKGROUND: Among primary cardiac tumors, atypical lipoma is very rare. In particular, cases with lipomas in both the pericardium and the atria are even rare. CASE PRESENTATION: We report the case of a 49-year-old male patient presented to our department...
Wed Jun 17, 2020 13:28
Related ArticlesOncologic outcomes, prognostic factor analysis and therapeutic algorithm evaluation of head and neck mucosal melanomas in France. Eur J Cancer. 2019 12;123:1-10 Authors: Moya-Plana A, Aupérin A, Obongo R, Baglin A, Ferrand FR, Baujat B, Saroul N, Casiraghi O, Vergez S, Herman P, Janot F, Thariat J, Vérillaud B, de Gabory L, REFCOR members Abstract BACKGROUND: Head and neck mucosal melanoma (HNMM) is aggressive and rare, with a poor prognosis...
Wed Jun 17, 2020 13:28
Related ArticlesSingle-cell proteolytic activity measurement using microfluidics for rare cell populations. Methods Enzymol. 2019;628:129-143 Authors: Chen YC, Yoon E Abstract Proteolytic degradation of the extracellular matrix represents a key step in cancer dissemination and metastasis. To probe cellular proteolytic activity, fluorescent sensing substrate was developed, yet prior studies focused on average activity of thousands of cells. Considerable...
Wed Jun 17, 2020 13:28
Related ArticlesDilemma in management of cervico-facial cystic hygroma. Med J Malaysia. 2019 10;74(5):450-451 Authors: Tamilselvi R, Tang IP, Linger S, Mohd Soffian MS Abstract Cervico facial cystic hygroma and tongue lymphagioma is rare representative of spectrum of lymphatic malformations. Conservative management with sclerosants alone has proven to be successful. However, sudden enlargement of these cervico facial lymphangiomas leads to catastrophic...
Wed Jun 17, 2020 13:28
Related ArticlesNot all swellings are lymph nodes! A case of subcutaneous panniculitis-like T-cell lymphoma. Med J Malaysia. 2019 10;74(5):441-442 Authors: Tee Evelyn Wy Yap CT, Evelyn Yap WY Abstract Subcutaneous Panniculitis-like T-cell Lymphoma (SPTL) is a rare cutaneous neoplasm of mature cytotoxic T cells, first described in 1991 by Gonzalez et al. The incidence of SPTL in Asian countries ranges from 2.3% to 3%. In Malaysia, only 5 cases were reported...
Wed Jun 17, 2020 13:28
Related ArticlesBone and Soft-Tissue Sarcoma Risk in Long-Term Survivors of Hereditary Retinoblastoma Treated With Radiation. J Clin Oncol. 2019 12 10;37(35):3436-3445 Authors: Kleinerman RA, Schonfeld SJ, Sigel BS, Wong-Siegel JR, Gilbert ES, Abramson DH, Seddon JM, Tucker MA, Morton LM Abstract PURPOSE: Survivors of hereditary retinoblastoma have excellent survival but substantially increased risks of subsequent bone and soft-tissue sarcomas, particularly...
Wed Jun 17, 2020 13:28
Related ArticlesMerkel cell carcinoma with divergent differentiation. Clin Exp Dermatol. 2020 Apr;45(3):327-332 Authors: Gaitskell K, Nassar S, Ibrahim H Abstract Merkel cell carcinoma (MCC) is a rare primary neuroendocrine carcinoma of the skin, usually occurring at sun-exposed sites in elderly people. Divergent differentiation in MCC, although rare, has been reported in previous case series. We describe two new cases of MCC with divergent differentiation....
Wed Jun 17, 2020 13:28
Related ArticlesIxazomib-Thalidomide-Dexamethasone for induction therapy followed by Ixazomib maintenance treatment in patients with relapsed/refractory multiple myeloma. Br J Cancer. 2019 10;121(9):751-757 Authors: Ludwig H, Poenisch W, Knop S, Egle A, Schreder M, Lechner D, Hajek R, Gunsilius E, Krenosz KJ, Petzer A, Weisel K, Niederwieser D, Einsele H, Willenbacher W, Melchardt T, Greil R, Zojer N Abstract BACKGROUND: Ixazomib-revlimid-dexamethason...
Wed Jun 17, 2020 13:28
Related ArticlesCTC-Derived Models: A Window into the Seeding Capacity of Circulating Tumor Cells (CTCs). Cells. 2019 09 25;8(10): Authors: Tayoun T, Faugeroux V, Oulhen M, Aberlenc A, Pawlikowska P, Farace F Abstract Metastasis is the main cause of cancer-related death owing to the blood-borne dissemination of circulating tumor cells (CTCs) early in the process. A rare fraction of CTCs harboring a stem cell profile and tumor initiation capacities is...
Wed Jun 17, 2020 13:28
Related ArticlesA rare case of intraductal tubulopapillary neoplasm of the pancreas - case report (with video). Postgrad Med. 2020 Apr;132(3):270-273 Authors: Dalal A, Patil G, Vadgaonkar A, Maydeo A Abstract Intraductal tubulopapillary neoplasm (ITPN) is a premalignant epithelial tumor of the pancreas. We report a case of ITPN detected incidentally during histopathology examination (HPE) from a specimen taken at the time of endosonography in a patient...
Wed Jun 17, 2020 13:28
Related ArticlesCheckpoint Inhibition May Trigger the Rare Variant of Anti-LAD-1 IgG-Positive, Anti-BP180 NC16A IgG-Negative Bullous Pemphigoid. Front Immunol. 2019;10:1934 Authors: Sadik CD, Langan EA, Grätz V, Zillikens D, Terheyden P Abstract Bullous pemphigoid (BP) is an autoimmune blistering skin disease characterized by an autoimmune response to type XVII collagen (BP180). The generation of anti-BP180-NC16A IgG autoantibodies is considered to...
Wed Jun 17, 2020 13:28
Related ArticlesClinical and Radiological Characteristics of Malignant Tumors Located to the Cerebellopontine Angle and/or Internal Acoustic Meatus. Otol Neurotol. 2019 10;40(9):1237-1245 Authors: Eliezer M, Tran H, Inagaki A, Vérillaud B, Takahashi M, Marie JP, Hautefort C, Herman P, Murakami S, Kania R Abstract OBJECTIVE: Metastatic lesions to the internal auditory meatus (IAM) and/or the cerebellopontine angle (CPA) are rare and may appear like a...
Wed Jun 17, 2020 13:28
Related ArticlesAnatomical Reconstruction of the Acromion Using an Autologous Iliac Crest Graft for Treatment of Recurrent Chondroblastoma: A Case Report. JBJS Case Connect. 2019 Jul-Sep;9(3):e0086 Authors: Herget GW, Maier D, Südkamp NP, Uhl M, Füllgraf H, Dovi-Akue D Abstract CASE: A 38-year-old man presented with recurrent chondroblastoma of the acromion after primary curettage and bone grafting. The patient underwent revision surgery with resection...
Wed Jun 17, 2020 13:28
Related ArticlesPerspectives of Patients With Dermatofibrosarcoma Protuberans on Diagnostic Delays, Surgical Outcomes, and Nonprotuberance. JAMA Netw Open. 2019 08 02;2(8):e1910413 Authors: David MP, Funderburg A, Selig JP, Brown R, Caliskan PM, Cove L, Dicker G, Hoffman L, Horne T, Gardner JM Abstract Importance: Dermatofibrosarcoma protuberans (DFSP) may have a deceptively benign clinical appearance, including a nonprotuberant presentation. Patients...
Wed Jun 17, 2020 13:28
Related ArticlesA Rare Lesion in Childhood: Gallbladder Tubular Adenoma. Indian J Pediatr. 2019 12;86(12):1153-1154 Authors: Demirbaş F, Çaltepe G, Demirel BD, Bilgici MC, Meydan BC PMID: 31468311 [PubMed - indexed for MEDLINE]
Wed Jun 17, 2020 13:28
Related ArticlesA Rare Cause of Hearing Impairment. Dtsch Arztebl Int. 2019 Jul 08;116(27-28):486 Authors: Reuter TC, Arndt S, Jakob TF PMID: 31431238 [PubMed - indexed for MEDLINE]
Wed Jun 17, 2020 13:28
Related ArticlesElastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma. J Clin Invest. 2019 08 01;129(11):4676-4681 Authors: Moore PC, Cortez JT, Chamberlain CE, Alba D, Berger AC, Quandt Z, Chan A, Cheng MH, Bautista JL, Peng J, German MS, Anderson MS, Oakes SA Abstract While improvements in genetic analysis have greatly enhanced our understanding of the mechanisms behind pancreatitis, it continues to afflict...
Wed Jun 17, 2020 13:28
Related ArticlesThe necessity for rigour in rare disease study design. Lancet Oncol. 2019 09;20(9):1190-1192 Authors: Baker LH PMID: 31331700 [PubMed - indexed for MEDLINE]
Wed Jun 17, 2020 13:28
Related ArticlesIntegrative Genomic Characterization Identifies Molecular Subtypes of Lung Carcinoids. Cancer Res. 2019 09 01;79(17):4339-4347 Authors: Laddha SV, da Silva EM, Robzyk K, Untch BR, Ke H, Rekhtman N, Poirier JT, Travis WD, Tang LH, Chan CS Abstract Lung carcinoids (LC) are rare and slow growing primary lung neuroendocrine tumors. We performed targeted exome sequencing, mRNA sequencing, and DNA methylation array analysis on macro-dissected...
Wed Jun 17, 2020 13:28
Related ArticlesSingle-Cell Analysis Reveals a Preexisting Drug-Resistant Subpopulation in the Luminal Breast Cancer Subtype. Cancer Res. 2019 09 01;79(17):4412-4425 Authors: Prieto-Vila M, Usuba W, Takahashi RU, Shimomura I, Sasaki H, Ochiya T, Yamamoto Y Abstract Drug resistance is a major obstacle in the treatment of breast cancer. Surviving cells lead to tumor recurrence and metastasis, which remains the main cause of cancer-related mortality. Breast...
Wed Jun 17, 2020 13:28
Related ArticlesDeciphering the genotype and phenotype of hairy cell leukemia: clues for diagnosis and treatment. Expert Rev Clin Immunol. 2019 08;15(8):857-867 Authors: Polderdijk MCE, Heron M, Kuipers S, Rijkers GT Abstract Introduction: Hairy cell leukemia (HCL) is a rare, indolent B-cell neoplasm. The classical variant of the disease is characterized by the BRAF V600E mutation, which is present in virtually all cases. How this mutation leads to the...
Wed Jun 17, 2020 13:28
Related ArticlesA Rare Case of Multiple Intracranial Cysts. Indian J Pediatr. 2019 12;86(12):1162-1163 Authors: Kumar I, Sharma S, Siddiqui Z, Aggarwal P, Verma A PMID: 31250348 [PubMed - indexed for MEDLINE]
Wed Jun 17, 2020 13:28
Related ArticlesFlow-mediated dilation shows impaired endothelial function in patients with mastocytosis. J Allergy Clin Immunol. 2019 10;144(4):1106-1111 Authors: Bucci T, Parente R, De Feo G, Cardamone C, Triggiani M Abstract BACKGROUND: Mastocytosis is a rare disease characterized by clonal proliferation of mast cells (MCs) in different organs. Clinical manifestations of mastocytosis are mostly due to release of mediators from MCs and, in many cases,...
Wed Jun 17, 2020 13:28
Related ArticlesPituitary Adenoma in Pediatric and Adolescent Populations. J Neuropathol Exp Neurol. 2019 07 01;78(7):626-632 Authors: Chen J, Schmidt RE, Dahiya S Abstract Pituitary adenomas are rare in children and adolescents and although mostly benign, they can sometimes be challenging to manage due to their locally invasive nature. In this study, we examined the clinicopathologic features of 42 pituitary adenomas in patients ≤21 years of age....
Wed Jun 17, 2020 13:28
Related ArticlesCharacterization of the Basal Ganglia Using Diffusion Tensor Imaging in Children with Self-Injurious Behavior and Tuberous Sclerosis Complex. J Neuroimaging. 2019 07;29(4):506-511 Authors: Gipson TT, Poretti A, Kelley SA, Carson KA, Johnston MV, Huisman TAGM Abstract BACKGROUND AND PURPOSE: Tuberous sclerosis complex (TSC) is a rare, genetic disease that is associated with multiple manifestations including epilepsy and autism. Self-injurious...
Wed Jun 17, 2020 13:28
Related ArticlesMalignant mesothelioma in Lynch syndrome: A report of two cases and a review of the literature. Am J Ind Med. 2019 05;62(5):448-452 Authors: Shih AR, Kradin RL Abstract Malignant mesothelioma is a rare and aggressive cancer most typically associated with prior asbestos exposure. The nature of the relationship between asbestos exposure and hereditary familial syndromes predisposing to malignancy has not been determined. We report two...
Wed Jun 17, 2020 13:28
Related ArticlesSurgical outcomes of patients with diffuse-type tenosynovial giant-cell tumours: an international, retrospective, cohort study. Lancet Oncol. 2019 06;20(6):877-886 Authors: Mastboom MJL, Palmerini E, Verspoor FGM, Rueten-Budde AJ, Stacchiotti S, Staals EL, Schaap GR, Jutte PC, Aston W, Gelderblom H, Leithner A, Dammerer D, Takeuchi A, Thio Q, Niu X, Wunder JS, TGCT Study Group, van de Sande MAJ Abstract BACKGROUND: Diffuse-type tenosynovial...
Wed Jun 17, 2020 13:28
Related ArticlesThe Theory of Unpleasant Symptoms in Pediatric Oncology Nursing: A Conceptual and Empirical Fit? J Pediatr Oncol Nurs. 2019 Nov/Dec;36(6):436-447 Authors: Silva-Rodrigues FM, Hinds PS, Nascimento LC Abstract Symptom management knowledge is a priority for pediatric oncology nursing research. Theories and models can frame the studies of symptoms experienced during childhood cancer. This article describes and analyzes the middle-range theory,...
Wed Jun 17, 2020 13:28
Related ArticlesNeed for arthrodesis following facetectomy for spinal peripheral nerve sheath tumors: an institutional experience and review of the current literature. J Neurosurg Spine. 2019 04 05;31(1):112-122 Authors: Sebai MA, Kerezoudis P, Alvi MA, Yoon JW, Spinner RJ, Bydon M Abstract OBJECTIVE: Spinal peripheral nerve sheath tumors (PNSTs) are a group of rare tumors originating from the nerve and its supporting structures. Standard surgical management...
Wed Jun 17, 2020 13:28
Related ArticlesDestructive arthropathy of the shoulder complicating a cervical ependymoma. Joint Bone Spine. 2019 Oct;86(5):642 Authors: Alaya Z PMID: 30890366 [PubMed - indexed for MEDLINE]
Wed Jun 17, 2020 13:28
Related ArticlesVisualization of Sequential Treatments in Metastatic Breast Cancer. JCO Clin Cancer Inform. 2019 03;3:1-8 Authors: Rocque GB, Kandhare PG, Williams CP, Nakhmani A, Azuero A, Burkard ME, Forero A, Bhatia S, Kenzik KM Abstract PURPOSE: Treatment sequencing of metastatic breast cancer (MBC) is heterogeneous. The primary objective of this study was to develop a visualization technique to understand population-level treatment sequencing for...
Wed Jun 17, 2020 13:28
Related ArticlesChordoid Glioma Infiltrating Optic Structures. J Neuroophthalmol. 2019 Sep;39(3):408-410 Authors: Sanda N, Mircea CN, Bernier M, Safran AB, Aldea S Abstract Chordoid glioma of the third ventricle (CGTV) is a rare, slow-growing, World Health Organization Grade II glial tumor, with stereotyped localization in the anterior third ventricle. Despite being considered a noninvasive tumor, CGTV is usually associated with a poor clinical outcome...
Wed Jun 17, 2020 13:28
Related ArticlesMRI features of mucinous adenocarcinoma of the prostate: report of four cases. Abdom Radiol (NY). 2019 04;44(4):1261-1268 Authors: Yamada K, Kozawa N, Nagano H, Fujita M, Yamada K Abstract CASE REPORTS: We report four patients with mucinous adenocarcinoma of the prostate, focusing on their magnetic resonance imaging (MRI) findings. The lesions appeared hyperintense on T2-weighted images (T2WI) in all four patients. In the two patients...
Wed Jun 17, 2020 13:28
Related ArticlesLimbs and trunk soft tissue sarcoma systematic local and remote monitoring by MRI and thoraco-abdomino-pelvic scanner: A single-centre retrospective study. Eur J Surg Oncol. 2019 Jul;45(7):1274-1280 Authors: De Angelis F, Guy F, Bertaut A, Méjean N, Varbedian O, Hervieu A, Truc G, Thibouw D, Barra CC, Fraisse J, Burnier P, Isambert N, Causeret S Abstract INTRODUCTION: Soft tissue sarcomas (STS) are rare malignant tumors that require...
Wed Jun 17, 2020 13:28
Related ArticlesTargeted Genomic Profiling of Acral Melanoma. J Natl Cancer Inst. 2019 10 01;111(10):1068-1077 Authors: Yeh I, Jorgenson E, Shen L, Xu M, North JP, Shain AH, Reuss D, Wu H, Robinson WA, Olshen A, von Deimling A, Kwok PY, Bastian BC, Asgari MM Abstract BACKGROUND: Acral melanoma is a rare type of melanoma that affects world populations irrespective of skin color and has worse survival than other cutaneous melanomas. It has relatively...
Wed Jun 17, 2020 13:28
Related ArticlesA Tough NUT to Crack: A 47-Year-Old With Diplopia From a Rare Malignancy. J Neuroophthalmol. 2019 03;39(1):129-133 Authors: Maloley L, Helvey J, Bridge J, DiMaio D, Ghate D, Kedar S PMID: 30640313 [PubMed - indexed for MEDLINE]
Wed Jun 17, 2020 13:28
Related ArticlesLiver scalloping: Pseudomyxoma peritonei liver compression. J Visc Surg. 2019 Feb;156(1):75-76 Authors: Allart K, Sabbagh C, Regimbeau JM Abstract Pseudomyxoma peritonei is a rare tumor characterized by the presence of mucous disseminated throughout the peritoneal cavity generally arising from the rupture of an appendicular mucocele. Liver scalloping is a highly suggestive image of pseudomyxoma and corresponds to the indentation of the...
Wed Jun 17, 2020 13:28
Related ArticlesDifferentiation between inflammatory myofibroblastic tumor and cholangiocarcinoma manifesting as target appearance on gadoxetic acid-enhanced MRI. Abdom Radiol (NY). 2019 04;44(4):1395-1406 Authors: Chang AI, Kim YK, Min JH, Lee J, Kim H, Lee SJ Abstract PURPOSE: To determine the differential features of inflammatory myofibroblastic tumor (IMT) and intrahepatic cholangiocarcinoma (ICC) manifesting as target appearance on gadoxetic acid-enhanced...
Wed Jun 17, 2020 13:28
Related ArticlesEpiscleral racemose hemangioma. J AAPOS. 2019 04;23(2):111-113 Authors: Lim LA, Brower P, Shields JA, Shields CL Abstract Racemose hemangioma is a rare, benign vascular malformation. In the episclera, it appears as dilated, tortuous blood vessels that pass from the fornix over the globe surface to the limbal area, without capillary architecture, and then loop backward into the fornix. Fluorescein angiogram reveals the vascular malformation...
Wed Jun 17, 2020 13:28
Related ArticlesBreast Tumor Resembling the Tall Cell Variant of Papillary Thyroid Carcinoma: Molecular Characterization by Next-Generation Sequencing and Histopathological Comparison With Tall Cell Papillary Carcinoma of Thyroid. Int J Surg Pathol. 2019 Apr;27(2):134-141 Authors: Zhong E, Scognamiglio T, D'Alfonso T, Song W, Tran H, Baek I, Hoda SA Abstract Recent publications have brought attention to the histopathological, immunohistochemical, and...
Wed Jun 17, 2020 13:28
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