IJMS, Vol. 21, Pages 4319: Apamin Suppresses LPS-Induced Neuroinflammatory Responses by Regulating SK Channels and TLR4-Mediated Signaling Pathways International Journal of Molecular Sciences doi: 10.3390/ijms21124319 Authors: Jihyun Park Kyung Mi Jang Kwan-Kyu Park Neuroinflammation plays a vital role in neurodegenerative conditions. Microglia are a key component of the neuroinflammatory response. There is a growing interest in developing drugs to target microglia and thereby...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4318: Post-Transcriptional Regulation of Alpha One Antitrypsin by a Proteasome Inhibitor International Journal of Molecular Sciences doi: 10.3390/ijms21124318 Authors: Lang Rao Yi Xu Lucas Charles Reineke Abhisek Bhattacharya Alexey Tyryshkin Jin Na Shin Tony Eissa Alpha one antitrypsin (α1AT), a serine proteinase inhibitor primarily produced by the liver, protects pulmonary tissue from neutrophil elastase digestion. Mutations of the SERPINA1...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4316: Comparative Transcriptome Analysis of Two Contrasting Soybean Varieties in Response to Aluminum Toxicity International Journal of Molecular Sciences doi: 10.3390/ijms21124316 Authors: Zhao Cui Cai Yang Liu Wang Gai Hu Li : Aluminum (Al) toxicity is a major factor limiting crop productivity on acid soils. Soybean (Glycine max) is an important oil crop and there is great variation in Al tolerance in soybean germplasms. However,...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4315: Artificial Sporulation Induction (ASI) by kinA Overexpression Affects the Proteomes and Properties of Bacillus subtilis Spores International Journal of Molecular Sciences doi: 10.3390/ijms21124315 Authors: Tu Abhyankar Swarge Wel Kramer Brul Koning To facilitate more accurate spore proteomic analysis, the current study focuses on inducing homogeneous sporulation by overexpressing kinA and assesses the effect of synchronized sporulation...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4314: The Role of Estrogen Receptors in Cardiovascular Disease International Journal of Molecular Sciences doi: 10.3390/ijms21124314 Authors: Aryan Younessi Zargari Banerjee Agopian Rahman Borna Ruffenach Umar Eghbali Cardiovascular Diseases (CVDs) are the leading cause of death globally. More than 17 million people die worldwide from CVD per year. There is considerable evidence suggesting that estrogen modulates cardiovascular...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4317: Cancer Immunotherapeutic Potential of NKTT320, a Novel, Invariant, Natural Killer T Cell-Activating, Humanized Monoclonal Antibody International Journal of Molecular Sciences doi: 10.3390/ijms21124317 Authors: Nishant P. Patel Peng Guan Devika Bahal Tanwir Hashem Felix Scheuplein Robert Schaub Kim E. Nichols Rupali Das Invariant natural killer T cells (iNKTs) directly kill tumor cells and trans-activate the anti-tumor functions of dendritic...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4313: The Metabolism of Epoxyeicosatrienoic Acids by Soluble Epoxide Hydrolase Is Protective against the Development of Vascular Calcification International Journal of Molecular Sciences doi: 10.3390/ijms21124313 Authors: Olivier Varennes Romuald Mentaverri Thomas Duflot Gilles Kauffenstein Thibaut Objois Gaëlle Lenglet Carine Avondo Christophe Morisseau Michel Brazier Saïd Kamel Isabelle Six Jeremy Bellien This study addressed the...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4311: The Connexin 43 Regulator Rotigaptide Reduces Cytokine-Induced Cell Death in Human Islets International Journal of Molecular Sciences doi: 10.3390/ijms21124311 Authors: Seyed Mojtaba Ghiasi Jakob Bondo Hansen Dan Ploug Christensen Björn Tyrberg Thomas Mandrup-Poulsen Background: Intercellular communication mediated by cationic fluxes through the Connexin family of gap junctions regulates glucose-stimulated insulin secretion and beta cell defense...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4310: Proteomic Screening for Prediction and Design of Antimicrobial Peptides with AmpGram International Journal of Molecular Sciences doi: 10.3390/ijms21124310 Authors: Michał Burdukiewicz Katarzyna Sidorczuk Dominik Rafacz Filip Pietluch Jarosław Chilimoniuk Stefan Rödiger Przemysław Gagat Antimicrobial peptides (AMPs) are molecules widespread in all branches of the tree of life that participate in host defense and/or microbial competition. Due...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4312: Approved and Emerging Disease Modifying Therapies on Neurodegeneration in Multiple Sclerosis International Journal of Molecular Sciences doi: 10.3390/ijms21124312 Authors: Madeline Bross Melody Hackett Evanthia Bernitsas Multiple sclerosis (MS) is an autoimmune, chronic, progressive disease leading to a combination of inflammation, demyelination, and neurodegeneration throughout the central nervous system (CNS). The outcome of these processes can be visualized...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4309: Current Perspectives on 89Zr-PET Imaging International Journal of Molecular Sciences doi: 10.3390/ijms21124309 Authors: Joon-Kee Yoon Bok-Nam Park Eun-Kyoung Ryu Young-Sil An Su-Jin Lee 89Zr is an emerging radionuclide that plays an essential role in immuno-positron emission tomography (PET) imaging. The long half-life of 89Zr (t1/2 = 3.3 days) is favorable for evaluating the in vivo distribution of monoclonal antibodies. Thus, the use of 89Zr is...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4308: The “Janus” Role of C/EBPs Family Members in Cancer Progression International Journal of Molecular Sciences doi: 10.3390/ijms21124308 Authors: Manlio Tolomeo Stefania Grimaudo CCAAT/enhancer-binding proteins (C/EBPs) constitute a family of transcription factors composed of six members that are critical for normal cellular differentiation in a variety of tissues. They promote the expression of genes through interaction with their promoters. Moreover, they...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4307: Characterization of HLA-G Regulation and HLA Expression in Breast Cancer and Malignant Melanoma Cell Lines upon IFN-γ Stimulation and Inhibition of DNA Methylation International Journal of Molecular Sciences doi: 10.3390/ijms21124307 Authors: Nanna Jørgensen Abid Sayed Helene Bjerregaard Jeppesen Gry Persson Iben Weisdorf Tina Funck Thomas Vauvert Faurschou Hviid The potential role of human leukocyte antigen (HLA)-G as a target for new cancer...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4301: Upregulation of miR-941 in Circulating CD14+ Monocytes Enhances Osteoclast Activation via WNT16 Inhibition in Patients with Psoriatic Arthritis International Journal of Molecular Sciences doi: 10.3390/ijms21124301 Authors: Shang-Hung Lin Ji-Chen Ho Sung-Chou Li Yu-Wen Cheng Yi-Chien Yang Jia-Feng Chen Chung-Yuan Hsu Toshiaki Nakano Feng-Sheng Wang Ming-Yu Yang Chih-Hung Lee Chang-Chun Hsiao Psoriatic arthritis (PsA) is a destructive...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4306: Ambient Air Pollution Increases the Risk of Cerebrovascular and Neuropsychiatric Disorders through Induction of Inflammation and Oxidative Stress International Journal of Molecular Sciences doi: 10.3390/ijms21124306 Authors: Omar Hahad Jos Lelieveld Frank Birklein Klaus Lieb Andreas Daiber Thomas Münzel Exposure to ambient air pollution is a well-established determinant of health and disease. The Lancet Commission on pollution and health concludes...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4305: Characterization and Analysis of the Full-Length Transcriptomes of Multiple Organs in Pseudotaxus chienii (W.C.Cheng) W.C.Cheng International Journal of Molecular Sciences doi: 10.3390/ijms21124305 Authors: Li Liu Zhen Wang Yingjuan Su Ting Wang Pseudotaxus chienii, a rare tertiary relict species with economic and ecological value, is a representative of the monotypic genus Pseudotaxus that is endemic to China. P. chienii can adapt well to habitat...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4304: Pomegranate Mesocarp against Colitis-Induced Visceral Pain in Rats: Effects of a Decoction and Its Fractions International Journal of Molecular Sciences doi: 10.3390/ijms21124304 Authors: Carmen Parisio Elena Lucarini Laura Micheli Alessandra Toti Mohamad Khatib Nadia Mulinacci Laura Calosi Daniele Bani Lorenzo Di Cesare Mannelli Carla Ghelardini The management of chronic visceral pain related to Inflammatory Bowel Diseases or Irritable...
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4303: CAR-T Cell Therapy International Journal of Molecular Sciences doi: 10.3390/ijms21124303 Authors: Aamir Ahmad CAR-T therapy has revolutionized the treatment of select hematological malignancies, namely, acute lymphoblastic leukemia and large B-cell lymphomas [...]
Wed Jun 17, 2020 03:00
IJMS, Vol. 21, Pages 4302: Identification and Characterization of Circular Intronic RNAs Derived from Insulin Gene International Journal of Molecular Sciences doi: 10.3390/ijms21124302 Authors: Debojyoti Das Aniruddha Das Mousumi Sahu Smruti Sambhav Mishra Shaheerah Khan Pruthvi R. Bejugam Pranita K. Rout Arundhati Das Shehnaz Bano Gyan Prakash Mishra Sunil K. Raghav Anshuman Dixit Amaresh C. Panda Circular RNAs (circRNAs) are a large family of noncoding...
Wed Jun 17, 2020 03:00
JCM, Vol. 9, Pages 1900: Prognostic Biomarkers in Endometrial Cancer: A Systematic Review and Meta-Analysis Journal of Clinical Medicine doi: 10.3390/jcm9061900 Authors: Eva Coll-de la Rubia Elena Martinez-Garcia Gunnar Dittmar Antonio Gil-Moreno Silvia Cabrera Eva Colas Endometrial cancer (EC) is the sixth most common cancer in women worldwide and its mortality is directly associated with the presence of poor prognostic factors driving tumor recurrence. Stratification...
Wed Jun 17, 2020 03:00
JCM, Vol. 9, Pages 1899: Regular Training Increases sTWEAK and Its Decoy Receptor sCD163–Does Training Trigger the sTWEAK/sCD163-Axis to Induce an Anti-Inflammatory Effect? Journal of Clinical Medicine doi: 10.3390/jcm9061899 Authors: Robert Schönbauer Michael Lichtenauer Vera Paar Michael Emich Monika Fritzer-Szekeres Christoph Schukro Jeanette Strametz-Juranek Michael Sponder Background: Low levels of soluble tumor necrosis factor-like weak inducer of apoptosis...
Wed Jun 17, 2020 03:00
JCM, Vol. 9, Pages 1898: Comparison of Three Nutritional Screening Tools with the New Glim Criteria for Malnutrition and Association with Sarcopenia in Hospitalized Older Patients Journal of Clinical Medicine doi: 10.3390/jcm9061898 Authors: Francesco Bellanti Aurelio Lo Buglio Stefano Quiete Giuseppe Pellegrino Michał Dobrakowski Aleksandra Kasperczyk Sławomir Kasperczyk Gianluigi Vendemiale The integrated assessment of nutritional status and presence of sarcopenia...
Wed Jun 17, 2020 03:00
JCM, Vol. 9, Pages 1895: Using Bayesian Networks to Predict Long-Term Health-Related Quality of Life and Comorbidity after Bariatric Surgery: A Study Based on the Scandinavian Obesity Surgery Registry Journal of Clinical Medicine doi: 10.3390/jcm9061895 Authors: Yang Cao Mustafa Raoof Eva Szabo Johan Ottosson Ingmar Näslund Previously published literature has identified a few predictors of health-related quality of life (HRQoL) after bariatric surgery. However, performance...
Wed Jun 17, 2020 03:00
JCM, Vol. 9, Pages 1893: Should We Continue Assessing Glomerular Filtration Rate with the Cockroft–Gault Formula in NOAC-Treated Patients? The Magnitude of the Problem Journal of Clinical Medicine doi: 10.3390/jcm9061893 Authors: Roberto Cemin Luisa Foco Carmine Zoccali Raffaele De Caterina Despite the proven superiority of the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) over the Cockcroft–Gault (CG) formula, current guidelines recommend the latter...
Wed Jun 17, 2020 03:00
JCM, Vol. 9, Pages 1896: Early Respiratory Impairment and Pneumonia after Hybrid Laparoscopically Assisted Esophagectomy—A Comparison with the Open Approach Journal of Clinical Medicine doi: 10.3390/jcm9061896 Authors: Martin Reichert Maike Lang Matthias Hecker Emmanuel Schneck Michael Sander Florian Uhle Markus A. Weigand Ingolf Askevold Winfried Padberg Veronika Grau Andreas Hecker Patients undergoing esophageal cancer surgery are at high risk of developing...
Wed Jun 17, 2020 03:00
JCM, Vol. 9, Pages 1897: Sacubitril/Valsartan Improves Autonomic Functionand Cardiopulmonary Parameters in Patients withHeart Failure with Reduced Ejection Fraction Journal of Clinical Medicine doi: 10.3390/jcm9061897 Authors: Francesco Giallauria Giuseppe Vitale Mario Pacileo Anna Di Lorenzo Alessandro Oliviero Francesco Passaro Roberta Calce Alessandro Parlato Crescenzo Testa Giuseppe D’Ambrosio Giuseppe Romano Francesco Clemenza Silvia Sarullo Elio...
Wed Jun 17, 2020 03:00
JCM, Vol. 9, Pages 1894: CAR-T Cell Therapy—An Overview of Targets in Gastric Cancer Journal of Clinical Medicine doi: 10.3390/jcm9061894 Authors: Dominika Bębnowska Ewelina Grywalska Paulina Niedźwiedzka-Rystwej Barbara Sosnowska-Pasiarska Jolanta Smok-Kalwat Marcin Pasiarski Stanisław Góźdź Jacek Roliński Wojciech Polkowski Gastric cancer (GC) is one of the most commonly diagnosed malignancies and, unfortunately, still has a high mortality rate. Recent research...
Wed Jun 17, 2020 03:00
JCM, Vol. 9, Pages 1892: Has Drug Repurposing Fulfilled its Promise in Acute Myeloid Leukaemia? Journal of Clinical Medicine doi: 10.3390/jcm9061892 Authors: Debora Valli Alicja M. Gruszka Myriam Alcalay Drug repurposing is a method of drug discovery that consists of finding a new therapeutic context for an old drug. Compound identification arises from screening of large libraries of active compounds, through interrogating databases of cell line gene expression response upon treatment...
Wed Jun 17, 2020 03:00
JCM, Vol. 9, Pages 1890: Prevalence of Migraine and Neuropathic Pain in Rheumatic Diseases Journal of Clinical Medicine doi: 10.3390/jcm9061890 Authors: Sylvain Mathieu Marion Couderc Bruno Pereira Jean-Jacques Dubost Sandrine Malochet-Guinamand Anne Tournadre Martin Soubrier Xavier Moisset To investigate the physiopathology of pain in chronic inflammatory rheumatic diseases (CIRDs), we assessed the prevalence of migraine and neuropathic pain in 499 patients with...
Wed Jun 17, 2020 03:00
JCM, Vol. 9, Pages 1891: Available Technologies, Applications and Benefits of Teleorthodontics. A Literature Review and Possible Applications during the COVID-19 Pandemic Journal of Clinical Medicine doi: 10.3390/jcm9061891 Authors: Cinzia Maspero Andrea Abate Davide Cavagnetto Mohamed El Morsi Andrea Fama Marco Farronato Background: COVID-2019 spread rapidly throughout the world from China. This infection is highly contagiousness, has a high morbidity, and is capable...
Wed Jun 17, 2020 03:00
JCM, Vol. 9, Pages 1889: Validation of FRIEND and ACSM Equations for Cardiorespiratory Fitness: Comparison to Direct Measurement in CAD Patients Journal of Clinical Medicine doi: 10.3390/jcm9061889 Authors: Won Young Jang Dong Oh Kang Yoonjee Park Jieun Lee Woohyeun Kim Jah Yeon Choi Seung-Young Roh Yuna Jang Se-Hyun Park Woo-Sub Kim Jin Oh Na Cheol Ung Choi Seung-Woon Rha Chang Gyu Park Hong Seog Seo Eung Ju Kim The regression equation of...
Wed Jun 17, 2020 03:00
JCM, Vol. 9, Pages 1888: Retraction: Ñíguez Sevilla, B., et al. Nurse’s A-Phase–Silicocarnotite Ceramic–Bone Tissue Interaction in a Rabbit Tibia Defect Model. J. Clin. Med. 2019, 8, 1714 Journal of Clinical Medicine doi: 10.3390/jcm9061888 Authors: JCM Editorial Office Editorial Office In the published paper [...]
Wed Jun 17, 2020 03:00
JFB, Vol. 11, Pages 43: “Monoclonal-Type” Plastic Antibodies for COVID-19 Treatment: What Is the Idea? Journal of Functional Biomaterials doi: 10.3390/jfb11020043 Authors: Puoci In late December 2019, an outbreak due to a novel coronavirus, initially called 2019-nCoV, was reported in Wuhan, China [...]
Wed Jun 17, 2020 03:00
Medicina, Vol. 56, Pages 299: Lactation Ketoacidosis: A Systematic Review of Case Reports Medicina doi: 10.3390/medicina56060299 Authors: Abdullah M. Al Al Alawi Asma Al Flaiti Henrik Falhammar Background and Objective: Lactation ketoacidosis is a rare cause of high anion gap metabolic acidosis affecting breastfeeding mothers. We aim to review and analyze all cases of lactation ketoacidosis reported. Materials and Methods: A systematic search of PubMed/MEDLINE and Cumulative Index...
Wed Jun 17, 2020 03:00
Medicina, Vol. 56, Pages 298: Tumor Suppressors—HTRA Proteases and Interleukin-12—in Pediatric Asthma and Allergic Rhinitis Patients Medicina doi: 10.3390/medicina56060298 Authors: Joanna Renke Eliza Wasilewska Sabina Kędzierska-Mieszkowska Katarzyna Zorena Sylwia Barańska Tomasz Wenta Anna Liberek Danuta Siluk Dorota Żurawa-Janicka Aleksandra Szczepankiewicz Marcin Renke Barbara Lipińska Background and objective: Allergy belongs to a group of mast cell-related...
Wed Jun 17, 2020 03:00
Membranes, Vol. 10, Pages 125: The Development of Electroconvection at the Surface of a Heterogeneous Cation-Exchange Membrane Modified with Perfluorosulfonic Acid Polymer Film Containing Titanium Oxide Membranes doi: 10.3390/membranes10060125 Authors: Violetta Gil Mikhail Porozhnyy Olesya Rybalkina Dmitrii Butylskii Natalia Pismenskaya One way to enhance mass transfer and reduce fouling in wastewater electrodialysis is stimulation of electroconvective mixing of the solution...
Wed Jun 17, 2020 03:00
Metabolites, Vol. 10, Pages 254: The Cardiac Lipidome in Models of Cardiovascular Disease Metabolites doi: 10.3390/metabo10060254 Authors: Mateusz M. Tomczyk Vernon W. Dolinsky Cardiovascular disease (CVD) is the leading cause of death worldwide. There are numerous factors involved in the development of CVD. Among these, lipids have an important role in maintaining the myocardial cell structure as well as cardiac function. Fatty acids (FA) are utilized for energy, but also contribute...
Wed Jun 17, 2020 03:00
Metabolites, Vol. 10, Pages 255: Comparison of Metabolomic Profiles of Organs in Mice of Different Strains Based on SPME-LC-HRMS Metabolites doi: 10.3390/metabo10060255 Authors: Katarzyna Burlikowska Iga Stryjak Joanna Bogusiewicz Bogumiła Kupcewicz Karol Jaroch Barbara Bojko Given that the extent to which genetics alters the metabolomic profile of tissues is still poorly understood, the current study aimed to characterize and investigate the metabolite profiles of brain,...
Wed Jun 17, 2020 03:00
Metabolites, Vol. 10, Pages 253: A Metabolic Perspective and Opportunities in Pharmacologically Important Safflower Metabolites doi: 10.3390/metabo10060253 Authors: Vimalraj Mani Seon-Kyeong Lee Yunsoo Yeo Bum-Soo Hahn Safflower (Carthamus tinctorius L.) has long been grown as a crop due to its commercial utility as oil, animal feed, and pharmacologically significant secondary metabolites. The integration of omics approaches, including genomics, transcriptomics, metabolomics,...
Wed Jun 17, 2020 03:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου