Related ArticlesAdvanced Prostate Cancer: Treatment Advances and Future Directions. Trends Cancer. 2020 Jun 10;: Authors: Swami U, R McFarland T, Nussenzveig R, Agarwal N Abstract Prostate cancer affects one in every nine men in the USA and is the second leading cause of cancer-related death. The treatment landscape of advanced prostate cancer is changing rapidly. Multiple agents including abiraterone, enzalutamide, apalutamide, darolutamide, docetaxel,...
Mon Jun 15, 2020 14:23
Related ArticlesTraining the generation Y plastic surgeon. J Plast Reconstr Aesthet Surg. 2020 May 25;: Authors: Koljonen V, Lassus P PMID: 32534895 [PubMed - as supplied by publisher]
Mon Jun 15, 2020 17:09
Related ArticlesEvaluating trends and analyses in plastic surgery research. J Plast Reconstr Aesthet Surg. 2020 May 08;: Authors: Zargaran D, Zargaran A PMID: 32534894 [PubMed - as supplied by publisher]
Mon Jun 15, 2020 17:09
Related ArticlesA compendium answering 150 questions on COVID-19 and SARS-CoV-2. Allergy. 2020 Jun 14;: Authors: Riggioni C, Comberiati P, Giovannini M, Agache I, Akdis M, Alves-Correia M, Antó JM, Arcolaci A, Kursat Azkur A, Azkur D, Beken B, Boccabella C, Bousquet J, Breiteneder H, Carvalho D, De Las Vecillas L, Diamant Z, Eguiluz-Gracia I, Eiwegger T, Eyerich S, Fokkens W, Gao YD, Hannachi F, Johnston SL, Jutel M, Karavelia A, Klimek L, Moya B, Nadeau K, O'Hehir...
Mon Jun 15, 2020 14:42
Related ArticlesLow skeletal muscle mass as predictor of postoperative complications and decreased overall survival in locally advanced head and neck squamous cell carcinoma: the role of ultrasound of rectus femoris muscle. Eur Arch Otorhinolaryngol. 2020 Jun 13;: Authors: Galli A, Colombo M, Carrara G, Lira Luce F, Paesano PL, Giordano L, Bondi S, Tulli M, Mirabile A, De Cobelli F, Bussi M Abstract PURPOSE: Skeletal muscle mass (SMM) depletion and...
Mon Jun 15, 2020 14:42
Related ArticlesMulti-operated cholesteatoma: when two surgeries are not enough. Eur Arch Otorhinolaryngol. 2020 Jun 13;: Authors: Hermann R, Blanc J, Fieux M, Desternes G, Coudert A, Truy E Abstract PURPOSE: Most studies regarding residual and recurrent cholesteatoma focus on single relapse. This study examines patients who had to undergo at least three surgeries for complete eradication of their cholesteatoma, with the aim of bringing to light...
Mon Jun 15, 2020 14:42
Related ArticlesHaller's vessels patterns in non-neovascular age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol. 2020 Jun 13;: Authors: Sacconi R, Cicinelli MV, Borrelli E, Savastano MC, Rispoli M, Lumbroso B, Corbelli E, Casaluci M, Bandello F, Querques G Abstract PURPOSE: To investigate the optical coherence tomography (OCT) en face reconstruction of the choroid in different phenotypes of non-neovascular age-related macular degeneration...
Mon Jun 15, 2020 14:42
Related ArticlesComparison of Therapeutic Results with/without Additional Hyperbaric Oxygen Therapy in Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Prospective Study. Audiol Neurootol. 2020 Jun 12;:1-6 Authors: Tong B, Niu K, Ku W, Xie W, Dai Q, Hellström S, Duan M Abstract OBJECTIVE: To assess the efficacy of the combination of hyperbaric oxygen (HBO) and pharmacological treatment in patients with idiopathic sudden sensorineural hearing...
Mon Jun 15, 2020 14:42
Related ArticlesDRH1 - a novel blood-based HPV tumour marker. EBioMedicine. 2020 Jun 11;56:102804 Authors: Weiland T, Eckert A, Tomazic PV, Wolf A, Pondorfer P, Vasicek S, Graupp M, Holzmeister C, Moser U, Andrianakis A, Kangler G, Kiss P, Brcic L, Kappler M, Wickenhauser C, Haak A, Krüger M, Al-Nawas B, Blatt S, Brockmeyer N, Skaletz-Rorowski A, Potthoff A, French LE, Charnowski S, Reinholz M, Kaufmann AM, Thies S, Lambrecht HG, Seliger B, Wild DC, Thurnher D ...
Mon Jun 15, 2020 14:42
Related ArticlesIrradiated homologous costal cartilage grafts for single-stage open airway reconstruction in severe subglottic stenosis for children under the age of one. Int J Pediatr Otorhinolaryngol. 2020 Jun 04;136:110167 Authors: Kherani S, Noel CW, Nazir T, Bitar MA Abstract We present two cases of premature infants with Cotton-Myer grade 3 subglottic stenosis where endoscopic balloon dilation failed. In an attempt to avoid tracheostomy, both...
Mon Jun 15, 2020 14:42
Related ArticlesCould sudden sensorineural hearing loss be the sole manifestation of COVID-19? An investigation into SARS-COV-2 in the etiology of sudden sensorineural hearing loss. Int J Infect Dis. 2020 Jun 11;: Authors: Kılıc O, Kalcıoglu MT, Cag Y, Tuysuz O, Pektas E, Caskurlu H, Cetın F Abstract OBJECTIVE: The aim of this study is to investigate the presence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in patients presenting...
Mon Jun 15, 2020 14:42
Related ArticlesThe omission of Level IIB in Early Oral Cancers: A word of caution. J Stomatol Oral Maxillofac Surg. 2020 Jun 11;: Authors: Subash A, Singh A, Sinha P Abstract The pattern of lymph nodal involvement in Head and Neck cancers is quite predictable. The extent of neck dissection over the years has evolved from a comprehensive one to a super-selective one. Multiple studies have shown the rarity of involvement of level IIB. The omission...
Mon Jun 15, 2020 14:42
Related ArticlesDental prevention of maxillo-mandibular osteoradionecrosis: a ten-year retrospective study. J Stomatol Oral Maxillofac Surg. 2020 Jun 11;: Authors: Dumoulin S, Maanen AV, Magremanne M Abstract INTRODUCTION: Osteoradionecrosis (ORN) remains a frequent complication of radiotherapy in head and neck cancer. As ORN management is often complex, it is essential to focus on its prevention, mainly by dental prophylaxis. The objectives of this...
Mon Jun 15, 2020 14:42
Related ArticlesSwallowing in individuals with disorders of consciousness: a cohort study. Ann Phys Rehabil Med. 2020 Jun 11;: Authors: Mélotte E, Maudoux A, Delhalle S, Lagier A, Thibaut A, Aubinet C, Kaux JF, Vanhaudenhuyse A, Ledoux D, Laureys S, Gosseries O Abstract BACKGROUND: After a period of coma, a proportion of individuals with severe brain injury remain in an altered state of consciousness before regaining partial or complete recovery....
Mon Jun 15, 2020 14:42
Related ArticlesOverexpression of kin of IRRE-Like protein 1 (KIRREL) as a prognostic biomarker for breast cancer. Pathol Res Pract. 2020 Jul;216(7):153000 Authors: Chen K, Zhao R, Yao G, Liu Z, Shi R, Geng J Abstract OBJECTIVES: The purpose of this study was to investigate the expression of Kin of IRRE-Like Protein 1 (KIRREL) and its clinicopathologic significance in breast cancer. MATERIALS AND METHODS: The mRNA and protein expressions...
Mon Jun 15, 2020 14:42
Related ArticlesRecommendations for head and neck surgical oncology practice in a setting of acute severe resource constraint during the COVID-19 pandemic: an international consensus. Lancet Oncol. 2020 Jun 11;: Authors: Mehanna H, Hardman JC, Shenson JA, Abou-Foul AK, Topf MC, AlFalasi M, Chan JYK, Chaturvedi P, Chow VLY, Dietz A, Fagan JJ, Godballe C, Golusiński W, Homma A, Hosal S, Iyer NG, Kerawala C, Koh YW, Konney A, Kowalski LP, Kraus D, Kuriakose MA, Kyrodimos...
Mon Jun 15, 2020 14:42
Related ArticlesSurgical management of carcinomas of the infratemporal fossa and skull base: patterns of failure and predictors of long-term outcomes. J Neurosurg. 2020 Jun 12;:1-7 Authors: Amit M, Bell D, Hunt PJ, Hanna E, Su SY, Kupferman M, Aashiq M, Takahashi H, Gidley PW, Nader ME, DeMonte F, Raza SM Abstract OBJECTIVE: Infratemporal fossa (ITF) tumors are unique in histological characteristics and difficult to treat. Predictors of patient outcomes...
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Abstract Background The pathogenesis of frontal fibrosing alopecia (FFA) is still unknown while hormonal factors have been postulated to play a role. There is scarce evidence with divergent results on the role of sex hormones in FFA. Aim To evaluate the possible association between sex hormone levels and FFA. Methods This study included 30 female cases of FFA and 34 healthy controls. Serum free testosterone, dehydroepiandrosterone sulfate (DHEAS), Luteinizing hormone (LH), Follicle‐stimulating...
Sun Jun 14, 2020 13:49
Abstract The hereditary leiomyomatosis and renal cell carcinoma syndrome (HLRCC) is defined by germline mutations in the fumarate hydratase (FH ) gene and associated with leiomyomas and aggressive renal cell carcinomas with FH deficiency. Here, we comprehensively characterize two new patients with HLRCC syndrome on a morphological, immunohistochemical and genetic level. The patients developed aggressive HLRCC syndrome‐associated RCC, uterine leiomyomas and dermal leiomyomas. One HLRCC syndrome‐associated...
Sun Jun 14, 2020 20:15
Related ArticlesStrategies for testing intervention matching schemes in cancer. Clin Pharmacol Ther. 2020 Jun 14;: Authors: Schork NJ, Goetz LH, Lowey J, Trent J Abstract Personalized Medicine, or the tailoring of health interventions to an individual's nuanced and often unique genetic, biochemical, physiological, behavioral and/or exposure profile, is seen by many as a biological necessity given the great heterogeneity of pathogenic processes underlying...
Mon Jun 15, 2020 14:36
Related ArticlesRate of Peritoneal Carcinomatosis in Resected Stage II and III Colon Cancer. Ann Surg Oncol. 2020 Jun 14;: Authors: Choi AH, Farzaneh C, Kejriwal N, Calidas A, Cordero-Caban K, Roman M, Kwong MLM, Selleck MJ, Pigazzi A, Jafari D, Senthil M Abstract INTRODUCTION: Incidence of peritoneal carcinomatosis (PC) after curative resection of stage II and III colon cancer varies widely. Although certain features are considered high risk for PC,...
Mon Jun 15, 2020 14:36
Related ArticlesReflux and dental disorders in the pediatric population: A systematic review. Int J Pediatr Otorhinolaryngol. 2020 Jun 08;136:110166 Authors: Lechien JR, Calvo-Henriquez C, Chiesa-Estomba CM, Barillari MR, Trozzi M, Meucci D, Peer S, Ben Abdelouahed F, Schindler A, Saussez S Abstract OBJECTIVES: To investigate the role of laryngopharyngeal reflux (LPR) or gastroesophageal reflux disease (GERD) in the development of dental disorders in...
Mon Jun 15, 2020 14:36
Related ArticlesTelehealth in Uro-oncology Beyond the Pandemic: Toll or Lifesaver? Eur Urol Focus. 2020 Jun 10;: Authors: Rodler S, Apfelbeck M, Schulz GB, Ivanova T, Buchner A, Staehler M, Heinemann V, Stief C, Casuscelli J Abstract BACKGROUND: Telehealth services are rapidly embraced in uro-oncology due to the current coronavirus disease 2019 (COVID-19) pandemic. OBJECTIVE: To determine patients' perspective on adoption of telehealth as a...
Mon Jun 15, 2020 14:36
Related ArticlesIn The Blood: Connecting Variant to Function In Human Hematopoiesis. Trends Genet. 2020 Jun 10;: Authors: Nandakumar SK, Liao X, Sankaran VG Abstract Genome-wide association studies (GWAS) have identified thousands of genetic variants associated with a range of human diseases and traits. However, understanding the mechanisms by which these genetic variants have an impact on associated diseases and traits, often referred to as the variant-to-function...
Mon Jun 15, 2020 14:36
Related ArticlesRoles of peroxisome proliferator-activated receptor α in the pathogenesis of ethanol-induced liver disease. Chem Biol Interact. 2020 Jun 11;:109176 Authors: Meng FG, Zhang XN, Liu SX, Wang YR, Zeng T Abstract Alcoholic liver disease (ALD) is a progressively aggravated liver disease with high incidence in alcoholics. Ethanol-induced fat accumulation and the subsequent lipopolysaccharide (LPS)-driven inflammation bring liver from reversible...
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Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00665C, PaperPeter E. Fowler, Jacob Zachary Pilgrim, Gyoung-il Lee, Gary A EicemanA planar tandem differential mobility spectrometer was integrated with a middle reactive stage to fragment ions, mobility selected in a first analyzer stage using characteristic compensation and separation fields. Fragmentation...The content of this RSS Feed (c) The Royal Society of Chemistry
Mon Jun 15, 2020 02:00
Abstract Introduction An unipedicular vertebral body stenting technique, termed ‘central stentoplasty’, was developed at our institution. With this technique, a single vertebral body stent was deployed percutaneously in the midline of the vertebral body using cone‐beam computed tomography (CBCT) guidance. Methods From September 2013 to July 2015, forty‐four patients with fifty‐six vertebral bodies underwent central stentoplasty. All fractures were of osteoporotic, traumatic or malignant...
Sun Jun 14, 2020 18:34
Abstract Triple‐negative breast cancer (TNBC) is a very aggressive subtype with high recurrence rate and no molecular targets for therapies. This subtype is characterized by high expression/secretion of the proinvasive/metastatic interleukin‐6 (IL‐6) cytokine. In the present study, we have shown that tocilizumab inhibits the IL‐6/STAT3 signaling and suppresses the cancer/inflammatory epigenetic IL‐6/STAT3/NF‐κB positive feedback loop. Furthermore, tocilizumab inhibited the proliferative and the...
Sun Jun 14, 2020 21:08
Key points Disruptions in circadian rhythms across an organism are associated with negative health outcomes, such as cardiometabolic and neurodegenerative diseases. Exercise has been proposed as a time cue for the circadian clock in rodents and humans In this study, we assessed the effect of a single bout of endurance exercise on the skeletal muscle clock in vivo and a bout of muscle contractions in vitro Timing of exercise or contractions influences the directional response of the muscle clock...
Sun Jun 14, 2020 16:08
Abstract Background Residual ridge resorption impairs patients’ satisfaction with complete denture (CD) treatment, but influence of bone resorption on the esthetic rehabilitation of edentulous patients still remains unclear due to insufficient quantitative investigations. Objectives To quantitatively evaluate the effects of residual ridge resorption on facial esthetic reconstruction in elderly edentulous patients. Methods According to radiological examination, a total of 19 edentulous...
Sun Jun 14, 2020 14:04
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