Antibodies, Vol. 9, Pages 26: The Roles of Autoimmunity and Biotoxicosis in Sick Building Syndrome as a “Starting Point” for Irreversible Dampness and Mold Hypersensitivity Syndrome Antibodies doi: 10.3390/antib9020026 Authors: Tuuminen Background: The terminology of “sick building syndrome” (SBS), meaning that a person may feel sick in a certain building, but when leaving the building, the symptoms will reverse, is imprecise. Many different environmental hazards...
Mon Jun 22, 2020 03:00
Antibodies, Vol. 9, Pages 25: Human Natural Antibodies to Mammalian Carbohydrate Antigens as Unsung Heroes Protecting against Past, Present, and Future Viral Infections Antibodies doi: 10.3390/antib9020025 Authors: Uri Galili Human natural antibodies to mammalian carbohydrate antigens (MCA) bind to carbohydrate-antigens synthesized in other mammalian species and protect against zoonotic virus infections. Three such anti-MCA antibodies are: (1) anti-Gal, also produced in Old-World monkeys...
Mon Jun 22, 2020 03:00
Antioxidants, Vol. 9, Pages 546: Antiarrhythmic Effects of Melatonin and Omega-3 Are Linked with Protection of Myocardial Cx43 Topology and Suppression of Fibrosis in Catecholamine Stressed Normotensive and Hypertensive Rats Antioxidants doi: 10.3390/antiox9060546 Authors: Barbara Szeiffova Bacova Csilla Viczenczova Katarina Andelova Matus Sykora Kiranj Chaudagar Miroslav Barancik Michaela Adamcova Vladimir Knezl Tamara Egan Benova Peter Weismann Jan Slezak Narcisa...
Mon Jun 22, 2020 03:00
Antioxidants, Vol. 9, Pages 545: Neuroprotection by Phytoestrogens in the Model of Deprivation and Resupply of Oxygen and Glucose In Vitro: The Contribution of Autophagy and Related Signaling Mechanisms Antioxidants doi: 10.3390/antiox9060545 Authors: Giuseppe Abbruzzese Javier Morón-Oset Sabela Díaz-Castroverde Nuria García-Font Cesáreo Roncero Francisco López-Muñoz José Luis Marco Contelles María Jesús Oset-Gasque Phytoestrogens can have a neuroprotective effect...
Mon Jun 22, 2020 03:00
Atmosphere, Vol. 11, Pages 665: Statistical Learning of the Worst Regional Smog Extremes with Dynamic Conditional Modeling Atmosphere doi: 10.3390/atmos11060665 Authors: Lu Deng Mengxin Yu Zhengjun Zhang This paper is concerned with the statistical learning of the extreme smog (PM 2 . 5 ) dynamics of a vast region in China. Differently from classical extreme value modeling approaches, this paper develops a dynamic model of conditional, exponentiated Weibull distribution...
Mon Jun 22, 2020 03:00
Atmosphere, Vol. 11, Pages 666: Evaluation of Hurricane Harvey (2017) Rainfall in Deterministic and Probabilistic HWRF Forecasts Atmosphere doi: 10.3390/atmos11060666 Authors: Mu-Chieh Ko Frank D. Marks Ghassan J. Alaka Sundararaman G. Gopalakrishnan Rainfall forecast performance was evaluated for the first time for the Hurricane Weather Research and Forecasting (HWRF) model. This study focused on HWRF performance in predicting rainfall from Hurricane Harvey in 2017. In particular,...
Mon Jun 22, 2020 03:00
Atmosphere, Vol. 11, Pages 667: Odor Characteristics and Concentration of Malodorous Chemical Compounds Emitted from a Combined Sewer System in Korea Atmosphere doi: 10.3390/atmos11060667 Authors: Park (1) Objectives: This study was carried out to investigate the characteristics of odors emitted from a combined sewer for the abatement of combined sewer odor. (2) Methods: The odor samples emitted from the combined sewer were collected at 14 sites, and the concentrations of 13 malodorous...
Mon Jun 22, 2020 03:00
Atmosphere, Vol. 11, Pages 664: The Polar Vortex and Extreme Weather: The Beast from the East in Winter 2018 Atmosphere doi: 10.3390/atmos11060664 Authors: James Overland Richard Hall Edward Hanna Alexey Karpechko Timo Vihma Muyin Wang Xiangdong Zhang Public attention has recently focused on high-impact extreme weather events in midlatitudes that originate in the sub-Arctic. We investigate movements of the stratospheric polar vortex (SPV) and related changes in lower...
Mon Jun 22, 2020 03:00
Biology, Vol. 9, Pages 134: A Brief Theory of Epidemic Kinetics Biology doi: 10.3390/biology9060134 Authors: François Louchet In the context of the COVID-19 epidemic, and on the basis of the Theory of Dynamical Systems, we propose a simple theoretical approach for the expansion of contagious diseases, with a particular focus on viral respiratory tracts. The infection develops through contacts between contagious and exposed people, with a rate proportional to the number of contagious...
Mon Jun 22, 2020 03:00
Biomolecules, Vol. 10, Pages 944: Anti-Bacterial and Anti-Candidal Activity of Silver Nanoparticles Biosynthesized Using Citrobacter spp. MS5 Culture Supernatant Biomolecules doi: 10.3390/biom10060944 Authors: Aftab Hossain Mondal Dhananjay Yadav Asghar Ali Neelofar Khan Jun O Jin Qazi Mohd Rizwanul Haq The present study described the extracellular synthesis of silver nanoparticles (AgNPs) using environmental bacterial isolate Citrobacter spp. MS5 culture supernatant....
Mon Jun 22, 2020 03:00
Biomolecules, Vol. 10, Pages 943: Comparative Genomics Reveals a Significant Sequence Variability of Myticin Genes in Mytilus galloprovincialis Biomolecules doi: 10.3390/biom10060943 Authors: Magalí Rey-Campos Beatriz Novoa Alberto Pallavicini Marco Gerdol Antonio Figueras Myticins are cysteine-rich antimicrobial peptides highly expressed in hemocytes of Mytilus galloprovincialis. Along with other antimicrobial peptides (AMPs), myticins are potent effectors in the mussel...
Mon Jun 22, 2020 03:00
Biomolecules, Vol. 10, Pages 942: TGF-β1 Activates Nasal Fibroblasts through the Induction of Endoplasmic Reticulum Stress Biomolecules doi: 10.3390/biom10060942 Authors: Jae-Min Shin Ju-Hyung Kang Joo-Hoo Park Hyun-Woo Yang Heung-Man Lee Ii-Ho Park (1) Background: Tissue remodeling and extracellular matrix (ECM) accumulation contribute to the development of chronic inflammatory diseases of the upper airway. Endoplasmic reticulum (ER) stress is considered to be the key...
Mon Jun 22, 2020 03:00
Biomolecules, Vol. 10, Pages 941: Biological Manganese Removal by Novel Halotolerant Bacteria Isolated from River Water Biomolecules doi: 10.3390/biom10060941 Authors: Van Khanh Nguyen Myung-Gyu Ha Ho Young Kang Dinh Duc Nguyen Manganese-oxidizing bacteria have been widely investigated for bioremediation of Mn-contaminated water sources and for production of biogenic Mn oxides that have extensive applications in environmental remediation. In this study, a total of 5 Mn-resistant...
Mon Jun 22, 2020 03:00
Biomolecules, Vol. 10, Pages 939: Development of Biodegradable Agar-Agar/Gelatin-Based Superabsorbent Hydrogel as an Efficient Moisture-Retaining Agent Biomolecules doi: 10.3390/biom10060939 Authors: Jyoti Chaudhary Sourbh Thakur Minaxi Sharma Vijai Kumar Gupta Vijay Kumar Thakur Downgrading in the yield of crop is due to the inadequate availability of water. The way out for this trouble is to construct synthetic resources dependent on natural polymers with great water absorption...
Mon Jun 22, 2020 03:00
Biomolecules, Vol. 10, Pages 940: The Effect of Chronic Methamphetamine Treatment on Schizophrenia Endophenotypes in Heterozygous Reelin Mice: Implications for Schizophrenia Biomolecules doi: 10.3390/biom10060940 Authors: Camilla Hume Shelley Massey Maarten van den Buuse Reelin has been implicated in the development of schizophrenia but the mechanisms involved in this interaction remain unclear. Chronic methamphetamine (Meth) use may cause dopaminergic sensitisation and psychosis...
Mon Jun 22, 2020 03:00
Biomolecules, Vol. 10, Pages 937: Exploring the Role of Non-Coding RNAs in the Pathophysiology of Systemic Lupus Erythematosus Biomolecules doi: 10.3390/biom10060937 Authors: Mohammad Taheri Reyhane Eghtedarian Marcel E. Dinger Soudeh Ghafouri-Fard Systemic lupus erythematosus (SLE) is a chronic immune-related disorder designated by a lack of tolerance to self-antigens and the over-secretion of autoantibodies against several cellular compartments. Although the exact pathophysiology...
Mon Jun 22, 2020 03:00
Biomolecules, Vol. 10, Pages 938: CoRNeA: A Pipeline to Decrypt the Inter-Protein Interfaces from Amino Acid Sequence Information Biomolecules doi: 10.3390/biom10060938 Authors: Kriti Chopra Bhawna Burdak Kaushal Sharma Ajit Kembhavi Shekhar C. Mande Radha Chauhan Decrypting the interface residues of the protein complexes provides insight into the functions of the proteins and, hence, the overall cellular machinery. Computational methods have been devised in the past to...
Mon Jun 22, 2020 03:00
Biosensors, Vol. 10, Pages 70: Laccase-Based Biosensor Encapsulated in a Galactomannan-Chitosan Composite for the Evaluation of Phenolic Compounds Biosensors doi: 10.3390/bios10060070 Authors: Imane Boubezari François Bessueille Anne Bonhomme Gaëtan Raimondi Ali Zazoua Abdelhamid Errachid Nicole Jaffrezic‑Renault Galactomannan, a neutral polysaccharide, was extracted from carob seeds and characterized. It was used for the first time for the fabrication of a laccase-based...
Mon Jun 22, 2020 03:00
Cancers, Vol. 12, Pages 1656: Diffusion Kurtosis Imaging—A Superior Approach to Assess Tumor–Stroma Ratio in Pancreatic Ductal Adenocarcinoma Cancers doi: 10.3390/cancers12061656 Authors: Philipp Mayer Yixin Jiang Tristan A. Kuder Frank Bergmann Ekaterina Khristenko Verena Steinle Jörg Kaiser Thilo Hackert Hans-Ulrich Kauczor Miriam Klauß Matthias M. Gaida Extensive desmoplastic stroma is a hallmark of pancreatic ductal adenocarcinoma (PDAC) and contributes...
Mon Jun 22, 2020 03:00
Cancers, Vol. 12, Pages 1655: MicroRNA-199b Downregulation Confers Resistance to 5-Fluorouracil Treatment and Predicts Poor Outcome and Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Patients Cancers doi: 10.3390/cancers12061655 Authors: Ion Cristóbal Jaime Rubio Andrea Santos Blanca Torrejón Cristina Caramés Laura Imedio Sofía Mariblanca Melani Luque Marta Sanz-Alvarez Sandra Zazo Juan Madoz-Gúrpide Federico Rojo Jesús García-Foncillas...
Mon Jun 22, 2020 03:00
Cancers, Vol. 12, Pages 1657: Two-Dimensional Theranostic Nanomaterials in Cancer Treatment: State of the Art and Perspectives Cancers doi: 10.3390/cancers12061657 Authors: Raja Kang Kim Jung Han As the combination of therapies enhances the performance of biocompatible materials in cancer treatment, theranostic therapies are attracting increasing attention rather than individual approaches. In this review, we describe a variety of two-dimensional (2D) theranostic nanomaterials...
Mon Jun 22, 2020 03:00
Cancers, Vol. 12, Pages 1653: HERC Ubiquitin Ligases in Cancer Cancers doi: 10.3390/cancers12061653 Authors: Joan Sala-Gaston Arturo Martinez-Martinez Leonardo Pedrazza L. Francisco Lorenzo-Martín Rubén Caloto Xosé R. Bustelo Francesc Ventura Jose Luis Rosa HERC proteins are ubiquitin E3 ligases of the HECT family. The HERC subfamily is composed of six members classified by size into large (HERC1 and HERC2) and small (HERC3–HERC6). HERC family ubiquitin...
Mon Jun 22, 2020 03:00
Cancers, Vol. 12, Pages 1654: Prognostic Effect of Comorbid Disease and Immune Gene Expression on Mortality in Kidney Cancer—A Population Based Study Cancers doi: 10.3390/cancers12061654 Authors: Chung-Shun Wong Tzu-Ting Chen Wei-Pin Chang Henry Sung-Ching Wong Mei-Yi Wu Wirawan Adikusuma Yuh-Feng Lin Wei-Chiao Chang The effect of comorbidities and the immune profiles of the kidney cancer microenvironment play a major role in patients’ prognosis and survival....
Mon Jun 22, 2020 03:00
Cancers, Vol. 12, Pages 1652: Predicting Response to Neoadjuvant Therapy in Colorectal Cancer Patients the Role of Messenger-and Micro-RNA Profiling Cancers doi: 10.3390/cancers12061652 Authors: Alberto Izzotti Chiara Ceccaroli Marta Geretto Filippo Grillo Ruggieri Sara Schenone Emilio Di Maria Colorectal cancer patients’ responses to neoadjuvant therapy undergo broad inter-individual variations. The aim of this systematic review is to identify a molecular signature...
Mon Jun 22, 2020 03:00
Cancers, Vol. 12, Pages 1651: Emerging Concepts and Novel Strategies in Radiation Therapy for Laryngeal Cancer Management Cancers doi: 10.3390/cancers12061651 Authors: Mauricio E. Gamez Adriana Blakaj Wesley Zoller Marcelo Bonomi Dukagjin M. Blakaj Laryngeal squamous cell carcinoma is the second most common head and neck cancer. Its pathogenesis is strongly associated with smoking. The management of this disease is challenging and mandates multidisciplinary care. Currently,...
Mon Jun 22, 2020 03:00
Cancers, Vol. 12, Pages 1650: Safety of BRAF+MEK Inhibitor Combinations: Severe Adverse Event Evaluation Cancers doi: 10.3390/cancers12061650 Authors: Tomer Meirson Nethanel Asher David Bomze Gal Markel Aim: The selective BRAF and MEK inhibitors (BRAFi+MEKi) have substantially improved the survival of melanoma patients with BRAF V600 mutations. However, BRAFi+MEKi can also cause severe or fatal outcomes. We aimed to identify and compare serious adverse events (sAEs) that are...
Mon Jun 22, 2020 03:00
Cancers, Vol. 12, Pages 1649: Exploiting Cancer’s Tactics to Make Cancer a Manageable Chronic Disease Cancers doi: 10.3390/cancers12061649 Authors: Kambiz Afrasiabi Mark E. Linskey Yi-Hong Zhou The history of modern oncology started around eighty years ago with the introduction of cytotoxic agents such as nitrogen mustard into the clinic, followed by multi-agent chemotherapy protocols. Early success in radiation therapy in Hodgkin lymphoma gave birth to the introduction of radiation...
Mon Jun 22, 2020 03:00
Cancers, Vol. 12, Pages 1648: An Anti-PSMA Immunotoxin Reduces Mcl-1 and Bcl2A1 and Specifically Induces in Combination with the BAD-Like BH3 Mimetic ABT-737 Apoptosis in Prostate Cancer Cells Cancers doi: 10.3390/cancers12061648 Authors: Anie P. Masilamani Viviane Dettmer-Monaco Gianni Monaco Toni Cathomen Irina Kuckuck Susanne Schultze-Seemann Nathalie Huber Philipp Wolf Background: Upregulation of anti-apoptotic Bcl-2 proteins in advanced prostate cancer leads...
Mon Jun 22, 2020 03:00
Cancers, Vol. 12, Pages 1647: Estrogen Signaling and Its Potential as a Target for Therapy in Ovarian Cancer Cancers doi: 10.3390/cancers12061647 Authors: Simon P. Langdon C. Simon Herrington Robert L. Hollis Charlie Gourley The estrogen receptor (ER) has functionality in selected ovarian cancer subtypes and represents a potential target for therapy. The majority (>80%) of high grade serous, low grade serous and endometrioid carcinomas and many granulosa cell tumors express...
Mon Jun 22, 2020 03:00
Cancers, Vol. 12, Pages 1646: COX5B-Mediated Bioenergetic Alteration Regulates Tumor Growth and Migration by Modulating AMPK-UHMK1-ERK Cascade in Hepatoma Cancers doi: 10.3390/cancers12061646 Authors: Yu-De Chu Wey-Ran Lin Yang-Hsiang Lin Wen-Hsin Kuo Chin-Ju Tseng Siew-Na Lim Yen-Lin Huang Shih-Chiang Huang Ting-Jung Wu Kwang-Huei Lin Chau-Ting Yeh The oxidative phosphorylation machinery in mitochondria, which generates the main bioenergy pool in cells,...
Mon Jun 22, 2020 03:00
Cells, Vol. 9, Pages 1525: Intratumoral Versus Circulating Lymphoid Cells as Predictive Biomarkers in Lung Cancer Patients Treated with Immune Checkpoint Inhibitors: Is the Easiest Path the Best One? Cells doi: 10.3390/cells9061525 Authors: Marta Gascón Dolores Isla Mara Cruellas Eva M. Gálvez Rodrigo Lastra Maitane Ocáriz José Ramón Paño Ariel Ramírez Andrea Sesma Irene Torres-Ramón Alfonso Yubero Julián Pardo Luis Martínez-Lostao The molecular and...
Mon Jun 22, 2020 03:00
Cells, Vol. 9, Pages 1523: Potential Prognostic Role of SPARC Methylation in Non-Small-Cell Lung Cancer Cells doi: 10.3390/cells9061523 Authors: Federico Pio Fabrizio Angelo Sparaneo Andrea Fontana Tommaso Mazza Paolo Graziano Angela Pantalone Paola Parente Flavia Centra Natalizia Orlando Domenico Trombetta Annamaria la Torre Gian Maria Ferretti Marco Taurchini Concetta Martina Di Micco Evaristo Maiello Vito Michele Fazio Antonio Rossi Lucia...
Mon Jun 22, 2020 03:00
Cells, Vol. 9, Pages 1522: New Frontiers in Prostate Cancer Treatment: Are We Ready for Drug Combinations with Novel Agents? Cells doi: 10.3390/cells9061522 Authors: Gaetano Aurilio Alessia Cimadamore Matteo Santoni Franco Nolè Marina Scarpelli Francesco Massari Antonio Lopez-Beltran Liang Cheng Rodolfo Montironi Medical treatment for metastatic castration-resistant prostate cancer (mCRPC) patients has progressively been evolving from a nonspecific clinical approach...
Mon Jun 22, 2020 03:00
Cells, Vol. 9, Pages 1521: Hepatogenic Potential and Liver Regeneration Effect of Human Liver-derived Mesenchymal-Like Stem Cells Cells doi: 10.3390/cells9061521 Authors: Jooyoung Lee Jiwan Choi Seoon Kang Jiye Kim Ryunjin Lee Seongjun So Young-In Yoon Varvara A. Kirchner Gi-Won Song Shin Hwang Sung-Gyu Lee Eunju Kang Eunyoung Tak Human liver-derived stem cells (hLD-SCs) have been proposed as a possible resource for stem cell therapy in patients with...
Mon Jun 22, 2020 03:00
Cells, Vol. 9, Pages 1520: The Function of Mitochondrial Calcium Uniporter at the Whole-Cell and Single Mitochondrion Levels in WT, MICU1 KO, and MICU2 KO Cells Cells doi: 10.3390/cells9061520 Authors: Syed Islamuddin Shah Ghanim Ullah Mitochondrial Ca2+ ([Ca2+]M) uptake through its Ca2+ uniporter (MCU) is central to many cell functions such as bioenergetics, spatiotemporal organization of Ca2+ signals, and apoptosis. MCU activity is regulated by several intrinsic proteins including...
Mon Jun 22, 2020 03:00
Cells, Vol. 9, Pages 1517: In-Depth Investigation of Low-Abundance Proteins in Matured and Filling Stages Seeds of Glycine max Employing a Combination of Protamine Sulfate Precipitation and TMT-Based Quantitative Proteomic Analysis Cells doi: 10.3390/cells9061517 Authors: Cheol Woo Min Joonho Park Jin Woo Bae Ganesh Kumar Agrawal Randeep Rakwal Youngsoo Kim Pingfang Yang Sun Tae Kim Ravi Gupta Despite the significant technical advancements in mass spectrometry-based...
Mon Jun 22, 2020 03:00
Cells, Vol. 9, Pages 1519: Isoleucine 44 Hydrophobic Patch Controls Toxicity of Unanchored, Linear Ubiquitin Chains through NF-κB Signaling Cells doi: 10.3390/cells9061519 Authors: Jessica R. Blount Kozeta Libohova Gustavo M. Silva Sokol V. Todi Ubiquitination is a post-translational modification that regulates cellular processes by altering the interactions of proteins to which ubiquitin, a small protein adduct, is conjugated. Ubiquitination yields various products, including...
Mon Jun 22, 2020 03:00
Cells, Vol. 9, Pages 1515: The S1P–S1PR Axis in Neurological Disorders—Insights into Current and Future Therapeutic Perspectives Cells doi: 10.3390/cells9061515 Authors: Alexandra Lucaciu Robert Brunkhorst Josef M. Pfeilschifter Waltraud Pfeilschifter Julien Subburayalu Sphingosine 1-phosphate (S1P), derived from membrane sphingolipids, is a pleiotropic bioactive lipid mediator capable of evoking complex immune phenomena. Studies have highlighted its importance regarding...
Mon Jun 22, 2020 03:00
Cells, Vol. 9, Pages 1516: Overlap of Peak Growth Activity and Peak IGF-1 to IGFBP Ratio: Delayed Increase of IGFBPs versus IGF-1 in Serum as a Mechanism to Speed up and down Postnatal Weight Gain in Mice Cells doi: 10.3390/cells9061516 Authors: Michael Walz Luong Chau Christina Walz Mandy Sawitzky Daniela Ohde Julia Brenmoehl Armin Tuchscherer Martina Langhammer Friedrich Metzger Christine Höflich Andreas Hoeflich Forced expression of insulin-like growth...
Mon Jun 22, 2020 03:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου