Abstract Here, QTL mapping for thousand-kernel weight carried out within a 541 × Ot1-3 population of recombinant inbred lines using high-density DArT-based map and three methods (single-marker analysis with F parametric test, marker analysis with the Kruskal–Wallis K* nonparametric test, and the recently developed analysis named genes interaction assorting by divergent selection with χ2 test) revealed 28 QTL distributed over all seven rye chromosomes. The first two methods showed...
Abstract RNA helicases are known from their ability to bind and unwind double-stranded RNA initiating RNA processing events. These evolutionary conserved RNA binding proteins are broadly expressed in a variety of tissues; however, we can distinguish those, which represent tissue-specific expression pattern and play unique roles in certain cell lineages. For instance, some RNA helicases mediate transcriptomic changes triggering cell differentiation which results in specification...
Abstract Brassica napus is an allopolyploid plant, derived from spontaneous hybridization between Brassica rapa and Brassica oleracea. Intensive breeding has led to a significant reduction in genetic and phenotypic diversity within this species. Newly resynthesized hybrids from progenitor species may restore some diversity in B. napus, but they often are chromosomally and phenotypically unstable. Using fluorescence in situ hybridization, we tested chromosome constitutions in a...
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Related ArticlesSchwannoma of the Greater Superficial Petrosal Nerve: An Unusual Site for a Common Tumor. J Neurol Surg A Cent Eur Neurosurg. 2020 May 03;: Authors: Uppar AM, Rao S, Prasad C, Arimappamagan A, Santosh V Abstract Greater superficial petrosal nerve (GSPN) schwannoma is a rare clinical entity. It forms a small subset of the larger group of facial nerve schwannomas. A thorough literature search yielded only 27 such cases reported to date...
Related ArticlesExtracellular Vesicles Derived from Neural Progenitor Cells--a Preclinical Evaluation for Stroke Treatment in Mice. Transl Stroke Res. 2020 May 02;: Authors: Zheng X, Zhang L, Kuang Y, Venkataramani V, Jin F, Hein K, Zafeiriou MP, Lenz C, Moebius W, Kilic E, Hermann DM, Weber MS, Urlaub H, Zimmermann WH, Bähr M, Doeppner TR Abstract Stem cells such as mesenchymal stem cells (MSCs) enhance neurological recovery in preclinical stroke models...
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Objective The aim of this study was to evaluate the usefulness of texture analysis of T2-weighted short inversion time inversion recovery (T2-STIR) for detecting myocardial tissue alterations in hypertrophic cardiomyopathy (HCM). Methods Twenty patients with HCM and 11 controls were examined. Texture analysis was performed for the hypertrophied regions with and without and abnormal hyperintensity (AHI) and for the interventricular septum of the controls on T2-STIR. T2 mapping was performed...
Objective The aim of the study was to quantitatively analyze the enhancement of breast lesions by contrast-enhanced spectral mammography to improve the differential diagnosis ability of contrast-enhanced spectral mammography. Methods A total of 283 patients with breast lesions admitted from August 2017 to May 2018 were retrospectively analyzed. Quantitative analysis of all enhancing lesions was performed to measure the gray values of the lesion region of interest (ROI), the area close...
Objective To establish the normal parameters of fetal lung development at different gestational ages and to study their correlation with gestational age, thereby providing clinicians with a noninvasive method for assessing fetal lung maturity. Methods Two hundred eight cases with pregnancy of 22 to 39 weeks plus 6 days were divided into 18 groups according to gestational age. Ultrasound Doppler was used to measure the relevant parameters of fetal pulmonary development, including right...
The authors investigated the usefulness of diffusion-tensor imaging (DTI) for evaluating tumor invasion depth, histologic grade, and lymph node metastasis in patients with cervical carcinoma (CC). Fifteen consecutive patients with histologically confirmed CC underwent 1.5-T magnetic resonance imaging and DTI. The CCs were clearly depicted as hypointense areas on all DTI maps. Fractional anisotropy, mean diffusivity, and axial diffusivity showed significantly inverse correlations with CC histologic...
Purpose The aims of the study were to assess the typical and atypical radiologic features of pathologically proven adrenal adenomas and to determine the relationship between the radiologic and histopathologic classification. Methods We retrospectively studied 156 pathologically proven adrenal adenomas in 154 patients from our institutional databases who have computed tomography (CT) and/or magnetic resonance imaging (MRI) examinations before intervention. We determined the histopathologic...
Objective The aim of this study was to evaluate the diagnostic ability of support vector machine (SVM) for early breast cancer (BC) using dedicated breast positron emission tomography (dbPET). Methods We evaluated 116 abnormal fluorodeoxyglucose (FDG) uptakes less than 2 cm on dbPET images in 105 women. Fluorodeoxyglucose uptake patterns and quantitative PET parameters were compared between BC and noncancer groups. Diagnostic accuracy of the SVM model including quantitative parameters...
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Stem Cells and Development, Ahead of Print.
Stem Cells and Development, Ahead of Print.
Stem Cells and Development, Ahead of Print.
Stem Cells and Development, Ahead of Print.
Stem Cells and Development, Volume 29, Issue 9, Page 586-598, May 1, 2020.
Stem Cells and Development, Ahead of Print.
Stem Cells and Development, Ahead of Print.
Stem Cells and Development, Ahead of Print.
Stem Cells and Development, Ahead of Print.
Stem Cells and Development, Ahead of Print.
Stem Cells and Development, Ahead of Print.
Stem Cells and Development, Ahead of Print.
Stem Cells and Development, Ahead of Print.
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Presentation of Case. Dr. John H. Stone: A 37-year-old man was evaluated in the rheumatology clinic of this hospital for joint pain and rash. The patient had been well until 2 years before this evaluation, when intermittent arthralgias developed in the joints of the hands. Four months before…
Presentation of Case. Dr. Sahir Kalim: A 29-year-old white man was evaluated at the nephrology clinic of this hospital because of hypertension, renal insufficiency, and hematuria. Eight months before the current evaluation, at a physical examination performed for employment, the patient was told he…
Presentation of Case. Dr. Xavier Guell (Medicine): A 24-year-old man was transferred to this hospital because of fever, fatigue, cough, and dyspnea. The patient had been well until 5 days before this presentation, when fatigue, malaise, fever, chills, and cough that was productive of terra…
Presentation of Case. Dr. Sarimer Sanchez (Medicine): A 37-year-old man was admitted to this hospital because of a facial droop, dysarthria, and kidney failure. The patient had been well until 1 week before admission, when weakness of the right arm and hand developed, along with difficulty with…
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Related ArticlesLong-term overall- and progression-free survival after pentostatin, cyclophosphamide and rituximab therapy for indolent non-Hodgkin lymphoma. Br J Haematol. 2019 05;185(4):670-678 Authors: Khashab T, Hagemeister F, Romaguera JE, Fanale MA, Pro B, McLaughlin P, Rodriguez MA, Neelapu SS, Fayad L, Younes A, Feng L, Vega F, Kwak LW, Samaniego F Abstract In a prospective phase II trial, pentostatin combined with cyclophosphamide and rituximab...
Related ArticlesExpression of GNAZ, encoding the Gαz protein, predicts survival in mantle cell lymphoma. Br J Haematol. 2019 05;185(4):708-712 Authors: Mundt F, Merrien M, Nygren L, Sutton LA, Christensson B, Wahlin BE, Rosenquist R, Sander B, Wasik AM Abstract Mantle cell lymphoma (MCL), a malignancy of B-lymphocytes, has a poor prognosis. It is thus necessary to improve the understanding of the pathobiology of MCL and identify factors contributing...
Related ArticlesEfficacy of venetoclax monotherapy in patients with relapsed chronic lymphocytic leukaemia in the post-BCR inhibitor setting: a UK wide analysis. Br J Haematol. 2019 05;185(4):656-669 Authors: Eyre TA, Kirkwood AA, Gohill S, Follows G, Walewska R, Walter H, Cross M, Forconi F, Shah N, Chasty R, Hart A, Broom A, Marr H, Patten PEM, Dann A, Arumainathan A, Munir T, Shankara P, Bloor A, Johnston R, Orchard K, Schuh AH, Fox CP, the UK CLL Forum Abstract...
Related ArticlesThe management of primary mediastinal B-cell lymphoma: a British Society for Haematology Good Practice Paper. Br J Haematol. 2019 05;185(3):402-409 Authors: Cwynarski K, Marzolini MAV, Barrington SF, Follows G, Illidge T, Stern S, Davies A, British Society for Haematology Guidelines PMID: 30609016 [PubMed - indexed for MEDLINE]
Related Articles[Chronic Lymphocytic Leukemia]. Ther Umsch. 2019;76(9):516-522 Authors: Schwarb H, Heim D Abstract Chronic Lymphocytic Leukemia Abstract. CLL is an indolent B-cell lymphoma characterized by a leukemic course. It is clinically and biologically very heterogeneous. The disease is preceded by a condition called monoclonal B lymphocytosis (MBL). The treatment of CLL has changed dramatically in recent years. Chemoimmunotherapy is being replaced...
Related ArticlesDose-limiting stomatitis associated with ibrutinib therapy: a case series. Br J Haematol. 2019 05;185(4):784-788 Authors: Vigarios E, Beylot-Barry M, Jegou MH, Oberic L, Ysebaert L, Sibaud V PMID: 30408164 [PubMed - indexed for MEDLINE]
Related ArticlesCell-of-origin in diffuse large B-cell lymphoma: findings from the UK's population-based Haematological Malignancy Research Network. Br J Haematol. 2019 05;185(4):781-784 Authors: Painter D, Barrans S, Lacy S, Smith A, Crouch S, Westhead D, Sha C, Patmore R, Tooze R, Burton C, Roman E PMID: 30408148 [PubMed - indexed for MEDLINE]
Related ArticlesA retrospective multicentre study of COCKLE, an oral chemotherapy regimen, as palliative treatment for high grade lymphoma. Br J Haematol. 2019 05;185(4):803-806 Authors: Maybury B, Kimpton G, Otton S PMID: 30407622 [PubMed - indexed for MEDLINE]
Related ArticlesGenetic analysis of Diffuse Large B-cell Lymphoma occurring in cases with antecedent Waldenström Macroglobulinaemia reveals different patterns of clonal evolution. Br J Haematol. 2019 05;185(4):767-770 Authors: Talaulikar D, Biscoe A, Lim JH, Gibson J, Arthur C, Mackinlay N, Saxena K, Cheng YY, Chen VM PMID: 30338525 [PubMed - indexed for MEDLINE]
Related ArticlesSerological normalisation as a surrogate marker for minimal residual disease negativity in multiple myeloma. Br J Haematol. 2019 05;185(4):775-778 Authors: Campbell L, Panitsas F, Basu S, Anyanwu F, Lee S, Ferry B, Ramasamy K PMID: 30338523 [PubMed - indexed for MEDLINE]
Related ArticlesDifferential expression of CD73, CD86 and CD304 in normal vs. leukemic B-cell precursors and their utility as stable minimal residual disease markers in childhood B-cell precursor acute lymphoblastic leukemia. J Immunol Methods. 2019 12;475:112429 Authors: Sędek Ł, Theunissen P, Sobral da Costa E, van der Sluijs-Gelling A, Mejstrikova E, Gaipa G, Sonsala A, Twardoch M, Oliveira E, Novakova M, Buracchi C, van Dongen JJM, Orfao A, van der Velden VHJ, Szczepański...
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