Related ArticlesSurvey Based Assessment of Burnout Rates Among US Plastic Surgery Residents. Ann Plast Surg. 2020 Apr 27;: Authors: Hart AM, Crowley C, Janis JE, Losken A Abstract PURPOSE: The purpose of this study was to analyze the rates of burnout and contributory factors among US plastic surgery residents. METHODS: The Maslach Burnout Inventory Human Services Survey was emailed to program coordinators of American College of Graduate Medical...
Thu Apr 30, 2020 15:05
Related ArticlesReliability and Versatility of Reverse Sural Island Neurofasciocutaneous Leg Flaps. Ann Plast Surg. 2020 Apr 27;: Authors: Stevanovic GR, Dakovic-Bjelakovic MZ, Paravina JM, Momčilović S, Golubovic IZ, Ignjatovic NS, Jankovic ID, Radojkovic M, Nestorovic M, Rancic D, Rancic Z Abstract BACKGROUND: Distally based sural neurofasciocutaneous (NFC) flaps are a commonly used method for foot and ankle reconstruction given that they are much...
Thu Apr 30, 2020 15:05
Abstract Bulk motion seriously degrades the image quality of optical coherence tomography angiography (OCTA). Conventional correction methods focus on in‐plane displacement, while the bulk motion component perpendicular to B‐Scans also introduces noise. This work firstly presents an evaluation of this component using a specific scan protocol and an approximate expression derived from peak‐normalized cross‐correlation values, and then quantitatively assesses how inter‐plane bulk motion noise reduce...
Sat May 02, 2020 15:15
Abstract Fourier‐transform infrared (FTIR) microspectroscopy is rounding the corner to become a label‐free routine method for cancer diagnosis. In order to build infrared‐spectral based classifiers, infrared images need to be registered with Hematoxylin and Eosin (H&E) stained histological images. While FTIR images have a deep spectral domain with thousands of channels carrying chemical and scatter information, the H&E images have only three color channels for each pixel and carry mainly...
Thu Apr 30, 2020 16:40
Abstract Although mice are widely used to elucidate factors contributing to penile disorders and develop treatment options, quantification of tissue changes upon intervention is either limited to minuscule tissue volume (histology) or acquired with limited spatial resolution (MRI/CT). Thus, imaging method suitable for expeditious acquisition of the entire mouse penis with subcellular resolution is described that relies on both aqueous‐ (CUBIC) and solvent‐based (FDISCO) tissue optical clearing...
Thu Apr 30, 2020 12:18
Abstract This report describes the treatment of a 44‐year‐old woman with history of left great toe amputation due to surgical complications from metatarsophalangeal joint fusion procedure. The fabrication of a prosthetic great toe with interchangeable nail that is paintable is described in detail. This prosthetic demonstrates that the clinical and laboratory techniques used in fabrication of traditional maxillofacial prosthetics can be adapted for the fabrication of somatic prosthetics to enhance...
Sat May 02, 2020 22:53
Related ArticlesA Computational Approach to Investigate the HDAC6 and HDAC10 Binding Propensity of Psidium guajava-derived Compounds as Potential Anticancer Agents. Curr Cancer Drug Targets. 2020 May 01;: Authors: Adewole KE, Ishola AA Abstract BACKGROUND: Psidium guajava is consumed as food and used for medicinal purposes around the world; with studies reporting its antiproliferative effects via different biochemical mechanisms, yet its modulatory effects...
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Related ArticlesEffect of Nectaroscordum koelzi Methanolic Extract on Acute and Chronic Inflammation in Male Mice. Curr Cancer Drug Targets. 2020 May 01;: Authors: Hasanvand KH, Khaksarian M, Alipour M, Mahmoudvand H, Naizi M, Nadri S Abstract INTRODUCTION: The present study deals with the effect of Nectaroscordum koelzi fruit extract on acute and chronic inflammation. METHODS: Totally, 84 NMRI mice were used in this study. The extract effect...
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Related ArticlesVaccine and Cell Based Therapeutic Approaches in Acute Myeloid Leukemia. Curr Cancer Drug Targets. 2020 May 01;: Authors: Agrawal V, Gbolahan OB, Stahl M, Zeidan AM, Zaid MA, Farag SS, Konig H Abstract Over the past decade, our increased understanding of the interactions between the immune system and cancer cells has led to paradigm shifts in the clinical management of solid and hematologic malignancies. The incorporation of immune-targeted...
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Related ArticlesNegative binomial additive model for RNA-Seq data analysis. BMC Bioinformatics. 2020 May 01;21(1):171 Authors: Ren X, Kuan PF Abstract BACKGROUND: High-throughput sequencing experiments followed by differential expression analysis is a widely used approach for detecting genomic biomarkers. A fundamental step in differential expression analysis is to model the association between gene counts and covariates of interest. Existing models...
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Related Articleswg-blimp: an end-to-end analysis pipeline for whole genome bisulfite sequencing data. BMC Bioinformatics. 2020 May 01;21(1):169 Authors: Wöste M, Leitão E, Laurentino S, Horsthemke B, Rahmann S, Schröder C Abstract BACKGROUND: Analysing whole genome bisulfite sequencing datasets is a data-intensive task that requires comprehensive and reproducible workflows to generate valid results. While many algorithms have been developed for tasks...
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Related ArticlesEnhancing fragment-based protein structure prediction by customising fragment cardinality according to local secondary structure. BMC Bioinformatics. 2020 May 01;21(1):170 Authors: Abbass J, Nebel JC Abstract BACKGROUND: Whenever suitable template structures are not available, usage of fragment-based protein structure prediction becomes the only practical alternative as pure ab initio techniques require massive computational resources...
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Related Articles2SigFinder: the combined use of small-scale and large-scale statistical testing for genomic island detection from a single genome. BMC Bioinformatics. 2020 Apr 29;21(1):159 Authors: Kong R, Xu X, Liu X, He P, Zhang MQ, Dai Q Abstract BACKGROUND: Genomic islands are associated with microbial adaptations, carrying genomic signatures different from the host. Some methods perform an overall test to identify genomic islands based on their...
Fri May 01, 2020 14:45
Related ArticlesCYPminer: an automated cytochrome P450 identification, classification, and data analysis tool for genome data sets across kingdoms. BMC Bioinformatics. 2020 Apr 29;21(1):160 Authors: Kweon O, Kim SJ, Kim JH, Nho SW, Bae D, Chon J, Hart M, Baek DH, Kim YC, Wang W, Kim SK, Sutherland JB, Cerniglia CE Abstract BACKGROUND: Cytochrome P450 monooxygenases (termed CYPs or P450s) are hemoproteins ubiquitously found across all kingdoms, playing...
Fri May 01, 2020 14:45
Related ArticlesAdaptations of Escherichia coli strains to oxidative stress are reflected in properties of their structural proteomes. BMC Bioinformatics. 2020 Apr 29;21(1):162 Authors: Mih N, Monk JM, Fang X, Catoiu E, Heckmann D, Yang L, Palsson BO Abstract BACKGROUND: The reconstruction of metabolic networks and the three-dimensional coverage of protein structures have reached the genome-scale in the widely studied Escherichia coli K-12 MG1655 strain....
Fri May 01, 2020 14:45
Related ArticlescircRNAprofiler: an R-based computational framework for the downstream analysis of circular RNAs. BMC Bioinformatics. 2020 Apr 29;21(1):164 Authors: Aufiero S, Reckman YJ, Tijsen AJ, Pinto YM, Creemers EE Abstract BACKGROUND: Circular RNAs (circRNAs) are a newly appreciated class of non-coding RNA molecules. Numerous tools have been developed for the detection of circRNAs, however computational tools to perform downstream functional analysis...
Fri May 01, 2020 14:45
Related ArticlesYSMR: a video tracking and analysis program for bacterial motility. BMC Bioinformatics. 2020 Apr 29;21(1):166 Authors: Schwanbeck J, Oehmig I, Dretzke J, Zautner AE, Groß U, Bohne W Abstract BACKGROUND: Motility in bacteria forms the basis for taxis and is in some pathogenic bacteria important for virulence. Video tracking of motile bacteria allows the monitoring of bacterial swimming behaviour and taxis on the level of individual cells,...
Fri May 01, 2020 14:45
Related ArticlesIntrinsic limitations in mainstream methods of identifying network motifs in biology. BMC Bioinformatics. 2020 Apr 29;21(1):165 Authors: Fodor J, Brand M, Stones RJ, Buckle AM Abstract BACKGROUND: Network motifs are connectivity structures that occur with significantly higher frequency than chance, and are thought to play important roles in complex biological networks, for example in gene regulation, interactomes, and metabolomes. Network...
Fri May 01, 2020 14:45
Related ArticlesPredicting potential adverse events using safety data from marketed drugs. BMC Bioinformatics. 2020 Apr 29;21(1):163 Authors: Daluwatte C, Schotland P, Strauss DG, Burkhart KK, Racz R Abstract BACKGROUND: While clinical trials are considered the gold standard for detecting adverse events, often these trials are not sufficiently powered to detect difficult to observe adverse events. We developed a preliminary approach to predict 135 adverse...
Fri May 01, 2020 14:45
Related ArticlesGrAPFI: predicting enzymatic function of proteins from domain similarity graphs. BMC Bioinformatics. 2020 Apr 29;21(1):168 Authors: Sarker B, Ritchie DW, Aridhi S Abstract An amendment to this paper has been published and can be accessed via the original article.PMID: 32349654 [PubMed - in process]
Fri May 01, 2020 14:45
Related ArticlesSpatialCPie: an R/Bioconductor package for spatial transcriptomics cluster evaluation. BMC Bioinformatics. 2020 Apr 29;21(1):161 Authors: Bergenstråhle J, Bergenstråhle L, Lundeberg J Abstract BACKGROUND: Technological developments in the emerging field of spatial transcriptomics have opened up an unexplored landscape where transcript information is put in a spatial context. Clustering commonly constitutes a central component in analyzing...
Fri May 01, 2020 14:45
Related ArticlesvivaGen - a survival data set generator for software testing. BMC Bioinformatics. 2020 Apr 29;21(1):167 Authors: Gietzelt M, Karmen C, Knaup-Gregori P, Ganzinger M Abstract An amendment to this paper has been published and can be accessed via the original article.PMID: 32349651 [PubMed - in process]
Fri May 01, 2020 14:45
Related ArticlesSleeve Gastrectomy: Surgical Technique, Outcomes, and Complications. Surg Technol Int. 2020 May 02;36: Authors: Felsenreich DM, Bichler C, Langer FB, Gachabayov M, Prager G Abstract The number of bariatric surgical procedures performed worldwide increases every year and has recently exceeded 685,000. Over 50% of these are laparoscopic sleeve gastrectomy (SG), and Roux-en-Y gastric bypass accounts for an additional 30%. Bariatric/metabolic...
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Related ArticlesObstructive sleep apnea in head and neck cancer survivors. Support Care Cancer. 2020 May 01;: Authors: Saesen K, van der Veen J, Buyse B, Nuyts S Abstract IMPORTANCE: Chronic fatigue is present in 33.0% of all head and neck cancer (HNC) survivors; this impacts their quality of life negatively. A plausible cause is obstructive sleep apnea (OSA) after HNC treatment. However, studies regarding this topic are scarce. OBJECTIVE: To...
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Related ArticlesAssociations between obstructive sleep apnea and prescribed opioids among veterans. Pain. 2020 Apr 29;: Authors: Chen K, Yaggi HK, Fiellin DA, DeRycke E, Athar W, Haskell S, Bastian LA Abstract Sleep disruption caused by obstructive sleep apnea (OSA) may be associated with hyperalgesia and may contribute to poor pain control and use of prescription opioids. However, the relationship between OSA and opioid prescription is not well described....
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Related ArticlesUnexpected occult malignancy diagnosed during tonsillectomy surgery for obstructive sleep apnea: A case report. Medicine (Baltimore). 2020 May;99(18):e19793 Authors: Park D, Lee BJ, Go M, Kim JS, Heo SJ Abstract RATIONALE: Many previous studies have investigated the necessity of routine histopathological analysis of tonsillectomy specimen, and most recent studies have suggested that such an analysis is not justified in asymptomatic patients...
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Related ArticlesSleep Disorders in Adolescents. Pediatrics. 2020 May;145(Suppl 2):S204-S209 Authors: Kansagra S Abstract Chronic sleep deprivation is a common, treatable condition among adolescents. Growing literature supports a myriad consequences that impact overall health, behavior, mood, and academic performance in this vulnerable age group during a time when there are rapid changes in physical development and emotional regulation. This article reviews...
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Related ArticlesTemporal Relationship Between Night-Time Gastroesophageal Reflux Events and Arousals From Sleep. Am J Gastroenterol. 2020 May;115(5):697-705 Authors: Shepherd K, Ockelford J, Ganasan V, Holloway R, Hillman D, Eastwood P Abstract INTRODUCTION: Night-time gastroesophageal reflux (nGER) symptoms are commonly associated with interrupted sleep. Most studies attempting to understand the relationship between sleep, arousal, and nGER events have...
Sat May 02, 2020 14:24
Related ArticlesPrevalence of malocclusions and oral dysfunctions in children with persistent sleep-disordered breathing after adenotonsillectomy in the long term. J Clin Sleep Med. 2020 May 01;: Authors: Cohen-Levy J, Quintal MC, Rompré P, Almeida F, Huynh N Abstract STUDY OBJECTIVES: To evaluate the prevalence of craniofacial/orthodontic abnormalities and oral dysfunctions in a population of children with persistent sleep-disordered breathing (SDB)...
Sat May 02, 2020 14:24
Related ArticlesPotential influences of obstructive sleep apnea and obesity on COVID-19 severity. J Clin Sleep Med. 2020 May 01;: Authors: McSharry D, Malhotra A PMID: 32356516 [PubMed - as supplied by publisher]
Sat May 02, 2020 14:24
Related ArticlesEvaluation of sleep-related respiratory disorders in patients with multiple sclerosis. Acta Neurol Belg. 2020 Apr 30;: Authors: Saçmacı H, Tanık N, Özcan SS, İntepe YS, Aktürk T, Çiftçi B, İnan LE Abstract Patients with multiple sclerosis (MS) often report fatigue, poor sleep and complaint of sleep disorders. Neurofilament light chain (NF-L) has been identified as a potential biomarker for disease progression in MS patients. In this study,...
Sat May 02, 2020 13:08
Related ArticlesA Randomized, Controlled, Pilot Study of CPAP for Patients with Chronic Cough and Obstructive Sleep Apnea. Lung. 2020 Apr 30;: Authors: Sundar KM, Willis AM, Smith S, Hu N, Kitt JP, Birring SS Abstract BACKGROUND: An association between chronic cough and obstructive sleep apnea (OSA) has been reported in prior studies with resolution or improvement in cough after continuous positive airway pressure (CPAP) therapy. Controlled studies of...
Sat May 02, 2020 13:08
Related ArticlesAdrenaline use as a poor predictor for the return of spontaneous circulation among victims of out-of-hospital cardiac arrest according to a national emergency medical services database. Turk J Emerg Med. 2020 Jan-Mar;20(1):18-21 Authors: Yuksen C, Phattharapornjaroen P, Kreethep W, Suwanmano C, Jenpanitpong C, Nonnongku R, Sittichanbuncha Y, Sawanyawisuth K Abstract OBJECTIVE: This study aimed to determine additional predictors of cardiopulmonary...
Sat May 02, 2020 13:08
Related ArticlesThe influence of fronto-facial monobloc advancement on obstructive sleep apnea: An assessment of 109 syndromic craniosynostoses cases. J Craniomaxillofac Surg. 2020 Apr 13;: Authors: Khonsari RH, Haber S, Paternoster G, Fauroux B, Morisseau-Durand MP, Cormier-Daire V, Legeai-Mallet L, James S, Hennocq Q, Arnaud E Abstract Obstructive sleep apnea syndrome is prevalent in children with syndromic craniosynostoses. Here we assessed the effects...
Sat May 02, 2020 13:08
Related Articles2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2019 08 20;74(7):e51-e156 Authors: Kusumoto FM, Schoenfeld MH, Barrett C, Edgerton JR, Ellenbogen KA, Gold MR, Goldschlager NF, Hamilton RM, Joglar JA, Kim RJ, Lee R, Marine...
Sat May 02, 2020 13:08
Effects of Solriamfetol on Quality of Life Measures From a 12-Week Phase 3 Randomized Trial. Ann Am Thorac Soc. 2020 Apr 30;: Authors: Weaver TE, Drake CL, Benes H, Stern T, Maynard J, Thein SG, Andry JM, Hudson JD, Chen D, Carter LP, Bron M, Lee L, Black J, Bogan RK Abstract RATIONALE: Excessive daytime sleepiness in patients with obstructive sleep apnea is associated with substantial burden of illness. OBJECTIVE: To assess solriamfetol, a...
Fri May 01, 2020 13:29
Indirect effects of obstructive sleep apnea treatments on work withdrawal: A quasi-experimental treatment outcome study. J Occup Health Psychol. 2020 Apr 30;: Authors: Carleton EL, Barling J Abstract The effect of sleep on work is now receiving appropriate research attention, yet most results have been based on community (i.e., nonclinical) populations. Based on previous findings that clinical treatment for diagnosed obstructive sleep apnea benefits...
Fri May 01, 2020 13:29
Mouth Breathing Impairs the Development of Temporomandibular Joint at a very Early Stage. Oral Dis. 2020 Apr 30;: Authors: Hu Z, Sun H, Wu Y, Wu X, Mei P, Wang B, Zhu M Abstract OBJECTIVES: The study aimed to explore the effects of mouth breathing and hypoxia on the condyle of temporomandibular joint(TMJ) via two animal models. METHODS: 24 four-week rats were randomly separated into three groups, consisting of eight control rats, eight intermittent...
Fri May 01, 2020 13:29
New Diagnosis of Obstructive Sleep Apnea Following Anterior Cervical Discectomy Complicated by Rheumatoid Arthritis: A Case Report. Cureus. 2020 Mar 27;12(3):e7439 Authors: Wasey W, Festic E, Sapra A, Rafi T, Bhandari P Abstract Obstructive sleep apnea (OSA) is the most common variant of sleep-disordered breathing that often goes undiagnosed. OSA is characterized mainly by anatomical obstruction or partial collapse of upper airways during sleep. The...
Fri May 01, 2020 13:29
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