Related ArticlesAutologous haematopoietic stem-cell transplantation versus bortezomib-melphalan-prednisone, with or without bortezomib-lenalidomide-dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study. Lancet Haematol. 2020 Apr 30;: Authors: Cavo M, Gay F, Beksac M, Pantani L, Petrucci MT, Dimopoulos MA, Dozza L, van der Holt B, Zweegman S, Oliva S, van...
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Related ArticlesGlial heterotopia of the middle ear. Eur Ann Otorhinolaryngol Head Neck Dis. 2020 Apr 28;: Authors: Quatre R, Baguant A, Gil H, Schmerber S Abstract INTRODUCTION: Glial heterotopia is defined as the presence of normal glial tissue in an abnormal site. CASE REPORT: We report the case of a 63-year-old man who presented with right hearing loss and tinnitus. ENT examination, computed tomography and magnetic resonance imaging showed...
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Abstract Background As common risk factors of dementia, nine factors (low education, hearing loss, obesity, hypertension, smoking, depression, physical inactivity, diabetes and social isolation) were proposed. However, the joint impact of these factors on incident dementia is still uncertain; hence, we aimed to examine this impact. Methods We conducted a cohort study of 9017 cognitively intact individuals aged ≥ 65 years in the Swedish Twin Registry. The main exposure was the...
Sun May 03, 2020 20:24
Abstract The prevalence of type 2 diabetes (T2D) is rapidly increasing worldwide. Obesity, physical inactivity and ageing increase the risk of T2D. Epigenetic modifications can change due to environmental exposures and may thereby predispose to disease. This review aims at summarizing recent advances in epigenetics related to T2D, with a special focus on impaired insulin action and secretion in humans. There will be an emphasis on analyses in human tissues; both from T2D case‐control cohorts...
Sun May 03, 2020 18:03
Ο παραδοσιακός κανόνας της τακτικής κατανάλωσης «τριών λαχανικών» από μια γυναίκα πριν την εγκυμοσύνη της μπορεί να μειώσει τον κίνδυνο πρόωρου τοκετού, υποστηρίζει μια νέα επιστημονική μελέτη που δημοσιεύθηκε στο American Journal of Clinical Nutrition. Στο πλαίσιο της μελέτης, η υποψήφια διδάκτωρ του Πανεπιστημίου του Queensland, Dereje Gete ανέλυσε τη διατροφή σχεδόν 3.500 γυναικών και διαπίστωσε ότι η υψηλή κατανάλωση σε καρότο, μπρόκολο, κολοκύθι, λάχανο, πράσινα φασόλια και πατάτες πριν τη...
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Οι άνδρες με ιστορικό παχυσαρκίας κατά τα τελευταία εφηβικά τους χρόνια διατρέχουν μεγαλύτερο κίνδυνο εν τω βάθει φλεβικής θρόμβωσης στα πόδια ή πνευμονικής θρομβοεμβολής κατά την ενήλικη ζωή τους, σύμφωνα με μία μελέτη που πραγματοποίησαν επιστήμονες από το Πανεπιστήμιο του Gothenburg και δημοσίευσαν στο Journal of Internal Medicine. Όπως επισημαίνεται, μάλιστα, ο κίνδυνος αυξάνεται διαδοχικά και είναι υψηλότερος σε άτομα που ήταν σοβαρά παχύσαρκα κατά την εφηβεία τους. Η φλεβική θρομβοεμβολή – η...
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Από την αρχή της επιδημίας, ερευνητές σε όλο τον κόσμο παρακολουθούν την εξάπλωση του ιού μέσω των αστικών λυμάτων, ενώ αρκετές επιστημονικές μελέτες έχουν δείξει τη σαφή παρουσία του COVID-19 στα κόπρανα των ασθενών. Για το λόγο αυτό, τα λύματα θα μπορούσαν να αποτελέσουν μια πολύτιμη «πηγή δεδομένων, που δείχνει εάν ο ιός κυκλοφορεί στον ανθρώπινο πληθυσμό και σε ποιο βαθμό. Αυτό υποστηρίζουν ένα ζευγάρι επιστημόνων, Willemijn Lodder και Ana Maria de Roda Husman από το Ολλανδικό Κέντρο Ελέγχου...
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1137 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/05/04PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Publication date: Available online 4 May 2020Source: Journal of ProteomicsAuthor(s): Apabrita Ayan Das, Kamalika Roy Choudhury, M.G. Jagadeeshaprasad, Mahesh J. Kulkarni, Prakash Chandra Mondal, Arun Bandyopadhyay
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Related ArticlesContributing factors for delayed postoperative cerebrospinal fluid leaks and suggested treatment algorithm. Int Forum Allergy Rhinol. 2020 May 03;: Authors: London NR, Mohyeldin A, Montaser AS, Tanjararak K, Prevedello DM, Otto BA, Carrau RL Abstract BACKGROUND: Delayed postoperative cerebrospinal fluid (CSF) leaks are uncommon and largely unstudied complications. In this study we aim to identify their etiology and understand the efficacy...
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Related ArticlesPredicting prolonged length of stay after endoscopic transsphenoidal surgery for pituitary adenoma. Int Forum Allergy Rhinol. 2020 May 03;: Authors: Vimawala S, Chitguppi C, Reilly E, Fastenberg JH, Garzon-Muvdi T, Farrell C, Rabinowitz MR, Rosen MR, Evans J, Nyquist GG Abstract BACKGROUND: Endoscopic transsphenoidal surgery (ETS) for the resection of pituitary adenoma has become more common throughout the past decade. Although most patients...
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Related ArticlesDysphagia worsens short-term outcomes in patients with acute exacerbation of heart failure. Heart Vessels. 2020 May 02;: Authors: Yokota J, Ogawa Y, Takahashi Y, Yamaguchi N, Onoue N, Shinozaki T, Kohzuki M Abstract Dysphagia, defined as a dysfunction in any stage or process of eating, is common in patients with acute exacerbation of heart failure (HF). In some diseases, dysphagia worsens in-hospital mortality, length of hospital stay,...
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Related ArticlesAcquired reactive perforating collagenosis in association with prostate adenocarcinoma, chronic lymphocytic leukemia, and Graves' disease. An Bras Dermatol. 2020 Apr 18;: Authors: Huseynova L, Akdogan N, Gököz Ö, Evans SE Abstract Acquired reactive perforating collagenosis is a rare skin disorder characterized by the presence of umbilicated pruritic papules and nodules. Transepidermal elimination of altered and perforating bundles of...
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Related ArticlesManagement of isolated retroperitoneal Castelman's disease: A case report. Int J Surg Case Rep. 2020 Apr 22;70:24-27 Authors: Imen BI, Zenaidi H, Abdelwahed Y, Sabeur R, Ayoub Z Abstract INTRODUCTION: Castleman's disease (CD) is a rare disorder characterized by benign angio follicular lymphoid hyperplasia, with gentle behavior. Its etiology and prevalence are unclear. It is usually found in the mediastinal area and it is rare to see this...
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Related ArticlesPerforative peritonitis confused with peritoneal dialysis-related peritonitis: Report of three cases. Int J Surg Case Rep. 2020 Apr 22;70:20-23 Authors: Arata R, Banshodani M, Yamashita M, Shintaku S, Moriishi M, Kawanishi H Abstract INTRODUCTION: Perforative peritonitis in patients on peritoneal dialysis (PD) is a serious adverse event associated with significant mortality. The signs and symptoms of perforative peritonitis in patients...
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Despite reproducing without sexual recombination, the root-knot nematode Meloidogyne incognita is adaptive and versatile. Indeed, this species displays a global distribution, is able to parasitize a large range of plants and can overcome plant resistance in a few generations. The mechanisms underlying this adaptability without sex remain poorly known and only low variation at the single nucleotide polymorphism level have been observed so far across different geographical isolates with distinct ranges...
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A near-universal Standard Genetic Code (SGC) implies a single origin for Earthly life. To study this unique event, I compute paths to the SGC, comparing different plausible histories. SGC-like coding tables emerge from traditional evolutionary mechanisms, and a superior route can be identified. To objectively measure evolution, progress values from 0 (random coding) to 1 (SGC-like) are defined: these measure fractions of random-code-to-SGC distance. Progress types are spacing/distance/delta Polar...
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Valiant (2009) proposed to treat Darwinian evolution as a special kind of computational learning from statistical queries. The statistical queries represent a genotype's fitness over a distribution of challenges. And this distribution of challenges along with the best response to them specify a given abiotic environment or static fitness landscape. Valiant's model distinguished families of environments that are "adaptable-to" from those that are not. But this model of evolution omits the vital ecological...
Sun May 03, 2020 03:00
Related ArticlesAdvances in cancer imaging require renewed radiotherapy dose and target volume concepts. Radiother Oncol. 2020 Apr 23;148:140-142 Authors: Kaanders JHAM, van den Bosch S, Dijkema T, Al-Mamgani A, Raaijmakers CPJ, Vogel WV Abstract Advances in diagnostic imaging create opportunities for improved therapeutic targeting of cancer but conceptual thinking about radiotherapy target volume definition and dose-prescription is not keeping up....
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Related ArticlesProspective longitudinal patient-reported outcomes of swallowing following intensity modulated proton therapy for oropharyngeal cancer. Radiother Oncol. 2020 Apr 21;148:133-139 Authors: Grant SR, Hutcheson KA, Ye R, Garden AS, Morrison WH, Rosenthal DI, Brandon Gunn G, Fuller CD, Phan J, Reddy JP, Moreno AC, Lewin JS, Sturgis EM, Ferrarotto R, Frank SJ Abstract BACKGROUND AND PURPOSE: With an enlarging population of long-term oropharyngeal...
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Related ArticlesHPV driven squamous cell head and neck cancer of unknown primary is likely to be HPV driven squamous cell oropharyngeal cancer. Oral Oncol. 2020 Apr 30;107:104721 Authors: Schroeder L, Pring M, Ingarfield K, Pawlita M, Leary SD, Thomas SJ, Waylen A, Waterboer T, Ness AR Abstract OBJECTIVES: To compare risk factors and survival in people with oropharyngeal cancer (OPC) and cancer unknown primary (CUP). MATERIALS AND METHODS:...
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Related ArticlesPost-treatment 18F-FDG PET/CT for predicting survival and recurrence in patients with advanced-stage head and neck cancer undergoing curative surgery. Oral Oncol. 2020 Apr 30;107:104750 Authors: Jung AR, Roh JL, Kim JS, Choi SH, Nam SY, Kim SY Abstract OBJECTIVES: Pre- and post-treatment 18F-FDG PET/CT may have a prognostic role in human cancers. 18F-FDG PET/CT after primary surgery for head and neck cancer might also predict survival....
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Related ArticlesThree-dimensional modeling of the scapular tip for anterolateral and lateral mandibular defects. Oral Oncol. 2020 Apr 30;107:104718 Authors: Marchiano E, Stevens JR, Liao E, Rosko AJ, Powell AR, Chinn SB, Stucken CL, Spector ME Abstract OBJECTIVE: Three-dimensional (3D) computational modeling represents an invaluable surgical tool for complex reconstructive cases. There exists limited data on 3D imaging to evaluate the use of the...
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Related ArticlesShould hearing targeted screening for congenital cytomegalovirus infection Be implemented? Int J Pediatr Otorhinolaryngol. 2020 Apr 23;134:110055 Authors: Haller T, Shoup A, Park AH Abstract Since 2013, after Utah became the first state to implement hearing targeted early CMV screening, a national debate has been percolating about whether this approach should be introduced nationally. Currently Utah, Iowa, Connecticut, and New York...
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Related ArticlesSleep endoscopy findings in children in supine versus left lateral position. Int J Pediatr Otorhinolaryngol. 2020 Apr 21;134:110056 Authors: Carr M, Phillips D Abstract OBJECTIVE: To describe how drug-induced sleep endoscopy (DISE) findings in children with obstructive sleep apnea (OSA) change with lateral positioning. METHODS: Children undergoing DISE for OSA in 2018-19 at a tertiary care children's hospital were positioned...
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Related ArticlesAtypical lymphoid hyperplasia in a patient undergoing tonsillectomy for severe obstructive sleep apnea. Int J Pediatr Otorhinolaryngol. 2020 Apr 24;134:110066 Authors: Kinealy BP, Harding BC, Vazmitsel MA, Laziuk K, Gov-Ari E Abstract Tonsillectomy is a common procedure in the pediatric population, with subsequent microscopic examination of the specimen for cancer and other rare diagnoses occurring routinely. A 17 year-old female...
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Related ArticlesEnlarged vestibular aqueduct: Intraoperative electrocochleography findings during cochlear implantation. Int J Pediatr Otorhinolaryngol. 2020 Apr 24;134:110065 Authors: Riggs WJ, Hiss MM, Varadarajan VV, Mattingly JK, Adunka OF Abstract Enlarged vestibular aqueduct (EVA) is the most frequent inner ear abnormality found on computed tomography in children with sensorineural hearing loss. The effects EVA abnormalities have on electrocochleography...
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Related ArticlesAcquisition limitations of bone conduction hearing devices in children with unilateral microtia and atresia. Int J Pediatr Otorhinolaryngol. 2020 Apr 06;134:110040 Authors: Alexander NL, Silva RC, Barton G, Liu YC Abstract OBJECTIVE: To characterize the use of bone conduction hearing devices (BCHD) for hearing management in children with unilateral congenital aural atresia (CAA) at a tertiary pediatric center's microtia clinic while...
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Related ArticlesAKT inhibition as a strategy for targeting hypoxic HPV-positive HNSCC. Radiother Oncol. 2020 Apr 30;: Authors: Göttgens EL, Bussink J, Ansems M, Hammond EM, Span PN Abstract BACKGROUND AND PURPOSE: Hypoxia negatively affects treatment outcome in both Human papillomavirus (HPV)-positive and -negative head and neck squamous cell carcinomas (HNSCC). Despite HPV-positive patients having a relatively good prognosis, hypoxic HPV-positive...
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Related ArticlesResponsiveness and Convergent Validity of a New Patient Reported outcome measure for Chronic Rhinosinusitis (CRS-PRO). J Allergy Clin Immunol Pract. 2020 Apr 30;: Authors: Ghadersohi S, Price CPE, Beaumont JL, Kern RC, Conley DB, Welch KC, Calice AM, Stanton E, VanderMeeden MK, Jensen SE, Peters AT, Grammer LC, Stevens WW, Schleimer RP, Tan BK Abstract BACKGROUND: The CRS-PRO is a new patient reported outcome measure (PROM) for chronic...
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Related ArticlesSingle-center prospective trial investigating the feasibility of serial FDG-PET guided adaptive radiotherapy for head and neck cancer. Int J Radiat Oncol Biol Phys. 2020 Apr 30;: Authors: Gouw ZAR, Fontaine, Vogel WV, van de Kamer JB, Sonke JJ, Al-Mamgani A Abstract INTRODUCTION: We investigated in a single-center prospective trial (NCT03376386) the use of serial FDG-PET/CT's to determine the boost dose and to guide boost segmentation...
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Related ArticlesTreatment response monitoring in patients with advanced malignancies using cell-free SHOX2 and SEPT9 DNA methylation in blood: An observational prospective study. J Mol Diagn. 2020 Apr 30;: Authors: de Vos L, Jung M, Koerber RM, Bawden EG, Holderried TAW, Dietrich J, Bootz F, Brossart P, Kristiansen G, Dietrich D Abstract Patients with incurable cancer usually receive palliative treatment with significant toxicity and limited efficacy....
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Related ArticlesACR Appropriateness Criteria Facilitate Judicious Use of CT Angiography for Stroke Workup in the Emergency Department. J Am Coll Radiol. 2020 Apr 28;: Authors: Hartman J, Goiney C, Carlson B, Moran S, Hippe DS, Zecevic M, Mossa-Basha M Abstract PURPOSE: CT angiography (CTA) of the head and neck plays a key role in the evaluation of patients with stroke in the emergency department, particularly to evaluate for large-vessel occlusion...
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Related ArticlesNon-Exudative Perifoveal Vascular Anomalous Complex: the sub-clinical stage of Perifoveal Exudative Vascular Anomalous Complex? Am J Ophthalmol. 2020 Apr 28;: Authors: Sacconi R, Borrelli E, Sadda S, Corradetti G, Freund KB, Yannuzzi LA, Souied E, Capuano V, Sarraf D, Querques L, Bandello F, Querques G Abstract PURPOSE: To describe pre-exudative stage of exudative Perifoveal Vascular Anomalous Complex (ePVAC) referred to as non-exudative...
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Related ArticlesReply to 'CORONA-steps for tracheotomy in COVID-19 patients: A staff-safe method for airway management' by Ferreli F. et al. Oral Oncol. 2020 Apr 27;:104743 Authors: Pichi B, Mazzola F, Bonsembiante A, Petruzzi G, Zocchi J, Moretto S, De Virgilio A, Pellini R PMID: 32360316 [PubMed - as supplied by publisher]
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Related ArticlesCOVID alias challenge to onco-rehabilitation and to viable indications and decisions: Cues from an Italian COVID+ oral cancer patient. Oral Oncol. 2020 Apr 24;:104745 Authors: Pietrobon G, Tagliabue M, Chu F, De Berardinis R, Ansarin M PMID: 32360315 [PubMed - as supplied by publisher]
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Related ArticlesAre Oral Pain and Otalgia Predictive of Perineural Invasion in Squamous Cell Carcinoma of the Oral Tongue? J Oral Maxillofac Surg. 2020 Apr 06;: Authors: Hechler B, Carlson ER, Heidel RE, Fahmy MD, McCoy JM Abstract PURPOSE: Tongue cancer is often associated with pain and perineural invasion. The purpose of the present study was to determine the association between tongue pain and otalgia and the microscopic identification of perineural...
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