Abstract Coronavirus disease 2019 (COVID-19) is a highly contagious infectious disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). From the epidemiological data, the picture emerges that the more severe etiopathologies among COVID-19 patients are found in elderly people. The risk of death due to COVID-19 increases exponentially with age. Eight out of 10 COVID-19 related deaths occur in people older than 65 years of age. Older patients with...
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22 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/08/06PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Aug 06, 2020 16:06
82 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/08/06PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Aug 06, 2020 15:25
2387 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/08/06PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Aug 06, 2020 17:35
2387 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/08/06PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Aug 06, 2020 13:33
Some of the Amazon’s smaller understory trees, juvenile members of the same species as the canopy trees, are capable of changing the way they process water to withstand drought conditions and still continue to grow up towards available light. (Pexels/)The Amazon rainforest’s future is in peril. Biologists and environmental scientists have known for some time that government policies that oppress Indigenous rights and allow logging have weakened the forest’s cohesion, while climate change has led...
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Not even a FastPass, FastPass+, or MaxPass can save you from the slow crawl of time. (Muti/)Waiting in line can test even the most patient person, but the happiest place on earth can make the longest of queues fly by. All it takes is these three tricks of the mind—no Disney magic necessary.When you wait for Space Mountain, for example, walls separate riders and twist the queue back and forth. This stops you from grasping the true number of folks ahead, dampening the urge to bow out of a seemingly...
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National parks are the crown jewel of America's public lands. Now, they will finally get updates to their aging infrastructures. (NPS Photo/J. Tobiason/)This story originally featured on Outdoor Life.For decades, the conservation community has been advocating for the full and permanent funding of the Land and Water Conservation Fund (LWCF), a program that uses royalties from offshore oil and gas operations to purchase new public lands and maintain public access. Today President Donald Trump—who has...
Thu Aug 06, 2020 21:30
Getting a hit in baseball is one of the hardest things to do regularly in sports. (Pexels/)There are few aspects of life where you can fail seven out of 10 times and still be considered great at what you do. With a 30 percent score on the MCAT, you wouldn’t get into medical school. You’d likely lose money if you only won 30 percent of your Super Bowl bets. But in baseball, if you get a hit 30 percent of the time you step up to the plate, you might be headed to the Hall of Fame—and that’s because...
Thu Aug 06, 2020 19:00
A place to store your leftovers. (Charles Deluvio via Unsplash/)There are dozens of reasons to invest in a good set of food storage containers. Saving your leftovers is cost effective, good for the environment, and saves you the time it would take to cook something fresh (or order takeout). A complete set also makes meal prep a snap, with standardized sizes, or compartments, for main and side dishes.We’ve chosen some of our favorites.For all of your leftovers. (Amazon/)These containers are our favorite,...
Thu Aug 06, 2020 17:56
Make these in your home! (Dallas Reedy via Unsplash/)Moldable, kinetic sand is an amazing, mess-free way for your kids to get creative or for you to stay focused and relieve some stress. This stuff is incredible. Like Play-doh or clay, it can help develop your child’s fine motor skills and provide hours of entertainment. Best of all, you won’t ever find yourself reaching for the broom because the sand is coated in silicone-based oils that loosely bind the particles together to keep it from spilling...
Thu Aug 06, 2020 17:46
Choose your filling. (Davide Ragusa via Unsplash/)Experimenting in the kitchen can be a fun adventure—especially when it involves making heavenly, cheesy ravioli. If you’re in the mood for cooking up this Italian staple but have no idea where to start, these four helpful gadgets have your back. They’re straightforward, efficient, and will have you eating all the delicious ravioli in no time.Makes twelve at a time. (Amazon/)This compact press is quick, simple, and churns out plenty of ravioli in one...
Thu Aug 06, 2020 17:42
Take your meals with you. (Kim Deachul via Unsplach/)Whether you’re packing food for a hangout in the park or a day at the office, meal prep bags are the perfect solution for fresh, organized nourishment. These handy satchels are insulated to help maintain temperature and offer roomy storage space to neatly stash your treats. You’ll save money on ordering out and avoid soggy messes.Here’s some of the best meal prep bags on the market.Comes with two sizes. (Amazon/)Organize your meals with this tricked...
Thu Aug 06, 2020 17:38
Yeah, being able to do this is cool and all, but simply walking over to the playground without is progress, too. (GMB Fitness/Unsplash/)Moving about isn’t meant to hurt. If you have normal range of motion, you should be able to stand, squat, walk, bend down, and reach over your head without any real effort or pain—and without having to warm up.Over the past year I’ve been working hard on moving better. I’ve gone from having shin splints and sore ankles when I run to bashing out 10Ks happy as anything....
Thu Aug 06, 2020 16:44
Family life is probably stressful right now, but it's also the perfect time to open up a dialogue with the younger members of your clan. (Pexels/)There’s a lot going on outside of the comforts of our homes right now. COVID-19 cases continue to skyrocket in some states. People are taking to the streets to speak up about violence and injustice against Black Americans. Hurricane season will soon be hitting its peak. And to top it all off, it’s a presidential election year.If you just felt a wave of...
Thu Aug 06, 2020 13:00
Related Articles scTyper: a comprehensive pipeline for the cell typing analysis of single-cell RNA-seq data. BMC Bioinformatics. 2020 Aug 04;21(1):342 Authors: Choi JH, In Kim H, Woo HG Abstract BACKGROUND: Recent advances in single-cell RNA sequencing (scRNA-seq) technology have enabled the identification of individual cell types, such as epithelial cells, immune cells, and fibroblasts, in tissue samples containing complex cell populations....
Thu Aug 06, 2020 14:35
Related Articles smsMap: mapping single molecule sequencing reads by locating the alignment starting positions. BMC Bioinformatics. 2020 Aug 04;21(1):341 Authors: Wei ZG, Zhang SW, Liu F Abstract BACKGROUND: Single Molecule Sequencing (SMS) technology can produce longer reads with higher sequencing error rate. Mapping these reads to a reference genome is often the most fundamental and computing-intensive step for downstream analysis. Most existing...
Thu Aug 06, 2020 14:35
Related Articles Application of multidirectional stitching technology in a laparoscopic suturing instructional program: a randomized controlled trial. BMC Med Educ. 2020 Aug 04;20(1):248 Authors: Zhao Y, Chen Q, Hu JN, Shen Q, Xia L, Yan LZ, Wang Y, Zhu XJ, Li WJ, Hu Y, Zhang Q Abstract BACKGROUND: Surgeon suturing technology plays a pivotal role in patient recovery after laparoscopic surgery. Intracorporal suturing and knot tying in minimally...
Thu Aug 06, 2020 13:44
Related Articles Impact of the Ebola virus disease outbreak (2014-2016) on tuberculosis surveillance activities by Guinea's National Tuberculosis Control Program: a time series analysis. BMC Public Health. 2020 Aug 04;20(1):1200 Authors: Magassouba AS, Diallo BD, Camara LM, Sow K, Camara S, Bah B, Barry AO, Diallo TH, Camara A, Bangoura AM, Sow OY Abstract BACKGROUND: Most countries in Subsaharan Africa have well-established National Tuberculosis...
Thu Aug 06, 2020 15:59
Related Articles The high cost of unpaid care by young people:health and economic impacts of providing unpaid care. BMC Public Health. 2020 Aug 05;20(1):1115 Authors: Brimblecombe N, Knapp M, King D, Stevens M, Cartagena Farias J Abstract BACKGROUND: Many countries worldwide have experienced reductions in provision of formal long-term care services amidst rising need for care. Provision of unpaid care, meanwhile, has grown. This includes care...
Thu Aug 06, 2020 15:59
Related Articles Socioeconomic inequalities in food insecurity and malnutrition among under-five children: within and between-group inequalities in Zimbabwe. BMC Public Health. 2020 Aug 04;20(1):1199 Authors: Lukwa AT, Siya A, Zablon KN, Azam JM, Alaba OA Abstract BACKGROUND: Food insecurity and malnutrition in children are pervasive public health concerns in Zimbabwe. Previous studies only identified determinants of food insecurity and malnutrition...
Thu Aug 06, 2020 15:59
Related Articles Natural history of recovery after intracerebral haemorrhage: a scoping review protocol. BMJ Open. 2020 Aug 04;10(8):e039460 Authors: Massicotte S, Lun R, Yogendrakumar V, Dewar B, Davies A, Fergusson DA, Shamy M, Dowlatshahi D Abstract INTRODUCTION: Clinical trials for intracerebral haemorrhage typically measure outcomes in the same way and at the same time points as trials for ischaemic stroke. However, there is growing evidence...
Thu Aug 06, 2020 16:45
Related Articles Reprocessing filtering facepiece respirators in primary care using medical autoclave: prospective, bench-to-bedside, single-centre study. BMJ Open. 2020 Aug 04;10(8):e039454 Authors: Harskamp RE, van Straten B, Bouman J, van Maltha-van Santvoort B, van den Dobbelsteen JJ, van der Sijp JR, Horeman T Abstract OBJECTIVE: There are widespread shortages of personal protective equipment as a result of the COVID-19 pandemic. Reprocessing...
Thu Aug 06, 2020 16:45
Related Articles Cross-sectional mixed-methods study protocol exploring the enablers and barriers for people with severe and enduring mental illness in Jamaica when accessing healthcare for chronic physical illness. BMJ Open. 2020 Aug 04;10(8):e038245 Authors: Whitehorne-Smith P, Burns S, Milbourn B, Abel W, Martin R Abstract INTRODUCTION: Extant international research suggests that people with severe and enduring mental illness (PWSEMI) experience...
Thu Aug 06, 2020 16:45
Related Articles FIRST-line support for assistance in breathing in children (FIRST-ABC): a master protocol of two randomised trials to evaluate the non-inferiority of high-flow nasal cannula (HFNC) versus continuous positive airway pressure (CPAP) for non-invasive respiratory support in paediatric critical care. BMJ Open. 2020 Aug 04;10(8):e038002 Authors: Richards-Belle A, Davis P, Drikite L, Feltbower R, Grieve R, Harrison DA, Lester J, Morris KP, Mouncey PR,...
Thu Aug 06, 2020 16:45
Related Articles Continuing medical education and work commitment among rural healthcare workers: a cross-sectional study in 11 western provinces in China. BMJ Open. 2020 Aug 04;10(8):e037985 Authors: Liu J, Mao Y Abstract OBJECTIVES: Continuing medical education (CME) and work commitment are important for rural healthcare workers (RHWs) and rural medical work. The significant association between continuing education and work commitment has...
Thu Aug 06, 2020 16:45
Related Articles Utility of the COM-B model in identifying facilitators and barriers to maintaining a healthy postnatal lifestyle following a diagnosis of gestational diabetes: a qualitative study. BMJ Open. 2020 Aug 04;10(8):e037318 Authors: Boyd J, McMillan B, Easton K, Delaney B, Mitchell C Abstract OBJECTIVES: Previous qualitative research investigating the experiences of women diagnosed with gestational diabetes (GD) has provided important...
Thu Aug 06, 2020 16:45
Related Articles What patients with lung cancer with comorbidity tell us about interprofessional collaborative care across healthcare sectors: qualitative interview study. BMJ Open. 2020 Aug 04;10(8):e036495 Authors: Bossert J, Forstner J, Villalobos M, Siegle A, Jung C, Deis N, Thomas M, Wensing M, Krug K Abstract BACKGROUND: Patients with lung cancer with comorbidity often require treatment and care by different health professionals, in different...
Thu Aug 06, 2020 16:45
Related Articles Meniscal Tear Outcome (METRO) review: a protocol for a systematic review summarising the clinical course and patient experiences of meniscal tears in the current literature. BMJ Open. 2020 Aug 04;10(8):e036247 Authors: Ahmed I, Khatri C, Parsons N, Hutchinson CE, Staniszewska S, Price AJ, Metcalfe A Abstract INTRODUCTION: Meniscal tears are a common knee injury with an incidence of 60 per 100 000. Management of meniscal tears...
Thu Aug 06, 2020 16:45
Related Articles Cost-effectiveness analysis of cinacalcet for haemodialysis patients with moderate-to-severe secondary hyperparathyroidism in China: evaluation based on the EVOLVE trial. BMJ Open. 2020 Aug 04;10(8):e034123 Authors: Liu L, Hong D, Ma K, Wu B, Lu X Abstract OBJECTIVE: As the cost-effectiveness evaluation of cinacalcet and conventional therapy in China has not been reported, the objective of this study was to make a pharmacoeconomic...
Thu Aug 06, 2020 16:45
Related Articles Sildenafil: how to make a bad situation worse. J Physiol. 2020 Aug 04;: Authors: Darby JRT PMID: 32754911 [PubMed - as supplied by publisher]
Thu Aug 06, 2020 15:10
Related Articles Maternal sildenafil impairs the cardiovascular adaptations to chronic hypoxemia in fetal sheep. J Physiol. 2020 Aug 04;: Authors: Inocencio IM, Polglase GR, Nitsos I, Miller SL, Allison BJ Abstract KEY POINTS: Fetal growth restriction induces a hemodynamic response which aims to maintain blood flow to vital organs such as the brain, in the face of chronic hypoxemia Maternal sildenafil treatment impairs the hypoxemia-driven hemodynamic...
Thu Aug 06, 2020 15:10
Related Articles Correction for Pearson et al., Securing timelines in the ancient Mediterranean using multiproxy annual tree-ring data. Proc Natl Acad Sci U S A. 2020 Aug 04;117(31):18891 Authors: PMID: 32753552 [PubMed - in process]
Thu Aug 06, 2020 13:15
Related Articles Reply to Manning: Dating of Gordion tree-ring sequence still stands within a year of 745 BC. Proc Natl Acad Sci U S A. 2020 Aug 04;117(31):18159-18160 Authors: Pearson C, Salzer M, Wacker L, Brewer P, Sookdeo A, Kuniholm P PMID: 32753551 [PubMed - in process]
Thu Aug 06, 2020 13:15
Related Articles Complications and challenges for securing Mediterranean timelines. Proc Natl Acad Sci U S A. 2020 Aug 04;117(31):18157-18158 Authors: Manning SW PMID: 32753550 [PubMed - in process]
Thu Aug 06, 2020 13:15
Related Articles Synthetic nanobodies as angiotensin receptor blockers. Proc Natl Acad Sci U S A. 2020 Aug 04;: Authors: McMahon C, Staus DP, Wingler LM, Wang J, Skiba MA, Elgeti M, Hubbell WL, Rockman HA, Kruse AC, Lefkowitz RJ Abstract There is considerable interest in developing antibodies as functional modulators of G protein-coupled receptor (GPCR) signaling for both therapeutic and research applications. However, there are few antibody...
Thu Aug 06, 2020 13:15
Related Articles A global view on how local muscular fatigue affects human performance. Proc Natl Acad Sci U S A. 2020 Aug 04;: Authors: Goethel MF, Gonçalves M, Brietzke C, Cardozo AC, Vilas-Boas JP, Ervilha UF Abstract There is a growing interest in scientific literature on identifying how and to what extent interventions applied to a specific body region influence the responses and functions of other seemingly unrelated body regions. To investigate...
Thu Aug 06, 2020 13:15
Related Articles Small proteins regulate Salmonella survival inside macrophages by controlling degradation of a magnesium transporter. Proc Natl Acad Sci U S A. 2020 Aug 04;: Authors: Yeom J, Shao Y, Groisman EA Abstract All cells require Mg2+ to replicate and proliferate. The macrophage protein Slc11a1 is proposed to protect mice from invading microbes by causing Mg2+ starvation in host tissues. However, the Mg2+ transporter MgtB enables the...
Thu Aug 06, 2020 13:15
Related Articles The whale shark genome reveals how genomic and physiological properties scale with body size. Proc Natl Acad Sci U S A. 2020 Aug 04;: Authors: Weber JA, Park SG, Luria V, Jeon S, Kim HM, Jeon Y, Bhak Y, Jun JH, Kim SW, Hong WH, Lee S, Cho YS, Karger A, Cain JW, Manica A, Kim S, Kim JH, Edwards JS, Bhak J, Church GM Abstract The endangered whale shark (Rhincodon typus) is the largest fish on Earth and a long-lived member of the...
Thu Aug 06, 2020 13:15
Related Articles Identification of MYC as an antinecroptotic protein that stifles RIPK1-RIPK3 complex formation. Proc Natl Acad Sci U S A. 2020 Aug 04;: Authors: Seong D, Jeong M, Seo J, Lee JY, Hwang CH, Shin HC, Shin JY, Nam YW, Jo JY, Lee H, Kim HJ, Kim HR, Oh JH, Ha SJ, Kim SJ, Roe JS, Kim W, Cheong JW, Bae KH, Lee SC, Oberst A, Vandenabeele P, Shin DH, Lee EW, Song J Abstract The underlying mechanism of necroptosis in relation to cancer...
Thu Aug 06, 2020 13:15
Related Articles MutS sliding clamps on an uncertain track to DNA mismatch repair. Proc Natl Acad Sci U S A. 2020 Aug 04;: Authors: Putnam CD PMID: 32753381 [PubMed - as supplied by publisher]
Thu Aug 06, 2020 13:15
Related Articles Nonreciprocity as a generic route to traveling states. Proc Natl Acad Sci U S A. 2020 Aug 04;: Authors: You Z, Baskaran A, Marchetti MC Abstract We examine a nonreciprocally coupled dynamical model of a mixture of two diffusing species. We demonstrate that nonreciprocity, which is encoded in the model via antagonistic cross-diffusivities, provides a generic mechanism for the emergence of traveling patterns in purely diffusive...
Thu Aug 06, 2020 13:15
Related Articles Nanoscale force sensing of an ultrafast nonlinear optical response. Proc Natl Acad Sci U S A. 2020 Aug 04;: Authors: Schumacher Z, Rejali R, Pachlatko R, Spielhofer A, Nagler P, Miyahara Y, Cooke DG, Grütter P Abstract The nonlinear optical response of a material is a sensitive probe of electronic and structural dynamics under strong light fields. The induced microscopic polarizations are usually detected via their far-field...
Thu Aug 06, 2020 13:15
Related Articles Polygenic inheritance, GWAS, polygenic risk scores, and the search for functional variants. Proc Natl Acad Sci U S A. 2020 Aug 04;: Authors: Crouch DJM, Bodmer WF Abstract The reconciliation between Mendelian inheritance of discrete traits and the genetically based correlation between relatives for quantitative traits was Fisher's infinitesimal model of a large number of genetic variants, each with very small effects, whose...
Thu Aug 06, 2020 13:15
Εάν θέλετε να ζήσετε περισσότερο το μυστικό είναι να μην παίρνετε το ασανσέρ, αλλά τις σκάλες, να κάνετε στρέτσινγκ και να παίζετε βόλεϊ, σύμφωνα με νέα έρευνα που δημοσιεύθηκε στο Medicine and Science in Sports and Exercise. Οι παραπάνω δραστηριότητες ήταν μεταξύ όσων συσχετίστηκαν με χαμηλότερα ποσοστά προώρου θανάτου βάσει έρευνας σε 27.000 ενήλικες 18-84 ετών του Πολιτειακού Πανεπιστημίου της Αριζόνα. Οι ερευνητές θέλησαν να εντοπίσουν ποιες δραστηριότητες συνέβαλαν περισσότερο στην μακροζωία....
Thu Aug 06, 2020 12:20
Τον καιρό που η κοινωνική κατασκευή του φύλου και η καταπίεση της γυναίκας έχουν τεθεί ως κυρίαρχα ζητήματα στην προοδευτική και όχι μόνο ατζέντα, με αφορμή τις βίαιες έως θανάσιμες επιθέσεις σε γυναίκες από άνδρες, την τοξική αρρενωπότητα και το κίνημα του «metoo», κοινή έρευνα από το Νοσοκομείο Παίδων UPMC του Πίτσμπουργκ και την αμερικανική ΜΚΟ Promundo για την εξάλειψη της βίας και την προαγωγή της ισότητας των (κοινωνικών) φύλων και της υγιούς αρρενωπότητας, φέρει στη συζήτηση την καταπίεση...
Thu Aug 06, 2020 09:01
Όπως αναφέρεται στο medRxiv (online αρχείο ερευνών που ακόμη δεν έχουν δημοσιευθεί σε επιστημονικό περιοδικό), ο βήχας, ο πυρετός και η απώλεια όσφρησης είναι τα συνήθη συμπτώματα της COVID-19, ωστόσο ανάμεσα στην ποικιλία των συμπτωμάτων βρίσκονται ο πονοκέφαλος, οι μυαλγίες, η κούραση, η διάρροια, η σύγχυση, η απώλεια όρεξης, η δυσκολία στην αναπνοή και πολλά άλλα. Για να προσδιορίσουν, λοιπόν, την έκταση των συμπτωμάτων, οι ερευνητές ανέλυσαν δεδομένα 1.600 ανθρώπων που ανέφεραν τα συμπτώματά...
Thu Aug 06, 2020 08:13
Βιβλιογραφική ανασκόπηση υπό το συντονισμό του Ινστιτούτου Καρολίνσκα στη Σουηδία και του Πανεπιστημίου McMaster στον Καναδά, η οποία δημοσιεύτηκε στο Mayo Clinic Proceedings, καταδεικνύει ότι οι υφασμάτινες μάσκες προσφέρουν αποτελεσματικά επίπεδα διήθησης για τη μείωση της εξάπλωσης των ιογενών σταγονιδίων και οι ειδικοί τονίζουν πως πρέπει να αποτελούν βασικό «όπλο» στη μάχη έναντι της COVID-19. Τυχαιοποιημένες ελεγχόμενες δοκιμές δεν υφίστανται, ωστόσο ο επικεφαλής της μελέτης, καθηγητής Επιδημιολογίας...
Thu Aug 06, 2020 07:56
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