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Κυριακή 3 Μαΐου 2020

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Nephroprotective effect of ferulic acid on gentamicin-induced nephrotoxicity in female rats.
Related ArticlesNephroprotective effect of ferulic acid on gentamicin-induced nephrotoxicity in female rats. Drug Chem Toxicol. 2020 Apr 30;:1-7 Authors: Erseçkin V, Mert H, İrak K, Yildirim S, Mert N Abstract Ferulic acid is a kind of phenolic compound that can be found in various fruits and vegetables. This study aims to investigate the effect of ferulic acid on nephrotoxicity induced by gentamicin (GM). In this study, rats were separated into 4 groups...
pubmed: "drug chem toxicol"[...
Sat May 02, 2020 13:18
High Protein Intake Among Preschoolers in Childcare in a Region at Elevated Risk for Obesity
Abstract Objectives To compare diet quality of convenience samples of children 2–3 and 4–5 years attending 11 of 75 childcare centers in Hays County, Texas to a nationally representative sample, as part of a needs assessment to inform a childcare center-based intervention. Methods Parents completed 24-h recalls of their child’s diet in 2014. Usual...
Latest Results for Maternal and Child Health Journal
Sat May 02, 2020 03:00
The Co-development and Feasibility-Testing of an Innovative Digital Animation Intervention (DAISI) to Reduce the Risk of Maternal Sepsis in the Postnatal Period
Abstract Introduction Sepsis is one of the most common causes of mortality in postnatal women globally and many other women who develop sepsis are left with severe morbidity. Women’s knowledge of postnatal sepsis and how it can be prevented by simple changes to behaviour is lacking. Methods This paper describes the co-development and feasibility testing...
Latest Results for Maternal and Child Health Journal
Thu Apr 30, 2020 03:00
Is There an Association Between Diet, Physical Activity and Depressive Symptoms in the Perinatal Period? An Analysis of the UPBEAT Cohort of Obese Pregnant Women
Abstract Introduction Depression is a common morbidity of the perinatal period (during pregnancy and up to one year postpartum). There is evidence for an association between diet and physical activity, and depression in the non-pregnant population but this association has been relatively less explored during the perinatal period; particularly poorly understood is the relationship between specific dietary components and depression. The...
Latest Results for Maternal and Child Health Journal
Thu Apr 30, 2020 03:00
Autism Insurance Mandates in the US: Comparison of Mandated Commercial Insurance Benefits Across States
Abstract Introduction Autism mandates are laws that require commercial insurers to cover certain evidence-based treatments for Autism Spectrum Disorder (ASD). The purpose of this study was to review state variability in autism insurance mandates and the benefits they cover and to discuss recommendations for research and policy to improve ASD services across states. Methods...
Latest Results for Maternal and Child Health Journal
Thu Apr 30, 2020 03:00
Racial Disparities in Prenatal Care Utilization and Infant Small for Gestational Age Among Active Duty US Military Women
Abstract Objectives To examine racial disparities in prenatal care (PNC) utilization and infant small for gestational age (SGA) among active duty US military women, a population with equal access to health care and known socioeconomic status. Methods Department of Defense Birth and Infant Health Research program data identified active duty women with...
Latest Results for Maternal and Child Health Journal
Thu Apr 30, 2020 03:00
Acceptability and Feasibility of Hair and Salivary Biomarker Collection Among Multiethnic School-Age Children
Abstract Objective As noninvasive biological markers gain increasing popularity in pediatric research, it is critical to understand how study participants perceive these measures, especially among groups underrepresented in biobehavioral research, like children and people of color. The purpose of this study was to examine acceptability and feasibility of hair and salivary biomarker collection in an urban community sample of ethnically...
Latest Results for Maternal and Child Health Journal
Thu Apr 30, 2020 03:00
Outstanding clinical efficacy of PD-1/PD-L1 inhibitors for pulmonary pleomorphic carcinoma
Publication date: June 2020Source: European Journal of Cancer, Volume 132Author(s): Jiyun Lee, Yoon La Choi, Hyun Ae Jung, Se-Hoon Lee, Jin Seok Ahn, Myung-Ju Ahn, Keunchil Park, Jong-Mu Sun
European Journal of Cancer
Sat May 02, 2020 13:14
How to determine kidney function in cancer patients?
Publication date: June 2020Source: European Journal of Cancer, Volume 132Author(s): Ben Sprangers, Ala Abudayyeh, Sheron Latcha, Mark A. Perazella, Kenar D. Jhaveri
European Journal of Cancer
Fri May 01, 2020 12:57
Human chorionic gonadotropin–positive seminoma patients: A registry compiled by the global germ cell tumor collaborative group (G3)
Publication date: June 2020Source: European Journal of Cancer, Volume 132Author(s): Christoph Seidel, Gedske Daugaard, Tim Nestler, Alexey Tryakin, Mikhail Fedyanin, Christian Fankhauser, Thomas Hermanns, Jorge Aparicio, Julia Heinzelbecker, Pia Paffenholz, Axel Heidenreich, Ugo De Giorgi, Richard Cathomas, Anja Lorch, Anna Fingerhut, Fabian Gayer, Felix Bremmer, Patrizia Giannatempo, Andrea Necchi, Gaetano Aurilio
European Journal of Cancer
Thu Apr 30, 2020 18:46
Recurrence pattern in the presence of hepatosteatosis in breast cancer: does it facilitate liver metastasis?
Related ArticlesRecurrence pattern in the presence of hepatosteatosis in breast cancer: does it facilitate liver metastasis? Future Oncol. 2020 May 01;: Authors: Kus T, Cinkir HY, Aktas G, Abali H Abstract Aim: We aimed to investigate the impact of hepatosteatosis (HS) severity on the recurrence pattern of breast cancer and to clarify whether HS causes affinity to recurrence with liver metastasis. Materials & methods: The median follow-up was 80.0...
Future Oncology.
Sat May 02, 2020 15:12
Phase II open-label study investigating apalutamide in patients with biochemical progression after radical prostatectomy.
Related ArticlesPhase II open-label study investigating apalutamide in patients with biochemical progression after radical prostatectomy. Future Oncol. 2020 May 01;: Authors: Dirix P, Strijbos M, den Mooter TV, Liefhooghe N, Bruwaene SV, Uvin P, Ghysel C, Ost D, Schatteman P, Bral S, Engels B, den Begin RV, Otte FX, Roumeguere T, Palumbo S, Neybuch Y, Fonteyne V, Ost P, Dirix L Abstract Apalutamide, a competent inhibitor of the androgen receptor, has...
Future Oncology.
Sat May 02, 2020 15:12
Analysis of differential metabolites in lung cancer patients based on metabolomics and bioinformatics.
Related ArticlesAnalysis of differential metabolites in lung cancer patients based on metabolomics and bioinformatics. Future Oncol. 2020 May 01;: Authors: Zhao C, Kong X, Han S, Li X, Wu T, Zhou J, Guo Y, Bu Z, Liu C, Zhang C, Jia Y Abstract Aim: Based on metabonomics, the metabolic markers of lung cancer patients were analyzed, combined with bioinformatics to explore the underlying disease mechanism. Materials & methods: Based on case-control design,...
Future Oncology.
Sat May 02, 2020 15:12
Telemedicine for cancer patients during COVID-19 pandemic: between threats and opportunities.
Related ArticlesTelemedicine for cancer patients during COVID-19 pandemic: between threats and opportunities. Future Oncol. 2020 May 01;: Authors: Elkaddoum R, Haddad FG, Eid R, Kourie HR PMID: 32356460 [PubMed - as supplied by publisher]
Future Oncology.
Sat May 02, 2020 15:12
Treatment sequence of first and second generation tyrosine kinase inhibitor followed by osimertinib in EGFR-mutated non-small-cell lung cancer: a real life study.
Treatment sequence of first and second generation tyrosine kinase inhibitor followed by osimertinib in EGFR-mutated non-small-cell lung cancer: a real life study. Future Oncol. 2020 Apr 30;: Authors: Girard N, Moro-Sibilot D, Bouée S, Emery C, Torreton E, Le Lay K, Luciani L, Maritaz C, Chouaid C Abstract Background: We aimed to assess the effectiveness and cost of patients with first line tyrosine kinase inhibitors (TKIs) sequence of first (1G) and...
Future Oncology.
Fri May 01, 2020 14:56
IMbrave 050: a Phase III trial of atezolizumab plus bevacizumab in high-risk hepatocellular carcinoma after curative resection or ablation.
IMbrave 050: a Phase III trial of atezolizumab plus bevacizumab in high-risk hepatocellular carcinoma after curative resection or ablation. Future Oncol. 2020 Apr 30;: Authors: Hack SP, Spahn J, Chen M, Cheng AL, Kaseb A, Kudo M, Lee HC, Yopp A, Chow P, Qin S Abstract Hepatocellular carcinoma recurs in 70-80% of cases following potentially curative resection or ablation and the immune component of the liver microenvironment plays a key role in recurrence....
Future Oncology.
Fri May 01, 2020 14:56
Colorectal signet ring cell carcinoma: advancing research in a rare cancer.
Colorectal signet ring cell carcinoma: advancing research in a rare cancer. Future Oncol. 2020 Apr 30;: Authors: Barresi V, Pedrazzani C PMID: 32351144 [PubMed - as supplied by publisher]
Future Oncology.
Fri May 01, 2020 14:56
Gmcsf and Ifnα gene therapy improves the response to BCG immunotherapy in a murine model of bladder cancer.
Gmcsf and Ifnα gene therapy improves the response to BCG immunotherapy in a murine model of bladder cancer. Future Oncol. 2020 Apr 30;: Authors: Tham SM, Mahendran R, Chiong E, Wu QH, Esuvaranathan K Abstract Aim: To develop a strategy to improve response to bacillus Calmette-Gueri (BCG) using cytokine gene therapy (Gmcsf + Ifnα). Materials & methods: MB49-PSA tumor-bearing C57BL/6N mice were assigned into four groups: control; Gmcsf + Ifnα therapy;...
Future Oncology.
Fri May 01, 2020 14:56
Renin–Angiotensin–Aldosterone System Blockers and the Risk of Covid-19
Studies in animals have shown that angiotensin-converting enzyme 2 (ACE2), a membrane-bound aminopeptidase that is abundantly expressed in the lungs, the heart, and other tissues, is used by coronaviruses as a functional receptor for their entrance into the cells. Angiotensin-receptor blockers…
NEJM : Research
Fri May 01, 2020 03:00
Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19
As the coronavirus disease 2019 (Covid-19) pandemic has spread around the globe, there has been growing recognition that persons with underlying increased cardiovascular risk may be disproportionately affected. Several studies of case series have noted cardiac arrhythmias, cardiomyopathy, and…
NEJM : Research
Fri May 01, 2020 03:00
Renin–Angiotensin–Aldosterone System Inhibitors and Risk of Covid-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), can infect host cells by means of interaction with membrane-bound angiotensin-converting enzyme 2 (ACE2) on respiratory epithelium. ACE2 is part of the…
NEJM : Research
Fri May 01, 2020 03:00
Association between Mental Disorders and Subsequent Medical Conditions
Persons with mental disorders are at increased risk for other types of mental disorders and for a range of general medical conditions. These medical conditions contribute to a decreased quality of life, increased health care utilization, and premature death in many persons with mental disorders.…
NEJM : Research
Thu Apr 30, 2020 03:00
Self-Contained Neuromusculoskeletal Arm Prostheses
Conventional arm and hand prostheses used after transhumeral amputations are attached to the humerus with a socket that compresses the stump and are moved by native biceps and triceps muscles without somatosensory feedback. Advanced prostheses for the upper arm use motors activated by signals from…
NEJM : Research
Thu Apr 30, 2020 03:00
Significance of recanalization of sinuses and resolution of parenchymal lesion in cerebral venous sinus thrombosis.
Related ArticlesSignificance of recanalization of sinuses and resolution of parenchymal lesion in cerebral venous sinus thrombosis. J Clin Neurosci. 2020 Apr 27;: Authors: Singh VK, Jain N, Kalita J, Misra UK, Kumar S Abstract In cerebral venous sinus thrombosis (CVST), the degree of recanalization may determine resolution of parenchymal lesion and clinical outcome. The aim of our study was to evaluate the relationship of recanalization with resolution...
J Clin Neurosci
Sat May 02, 2020 13:04
Clinicopathological overlap of neurodegenerative diseases: A comprehensive review.
Related ArticlesClinicopathological overlap of neurodegenerative diseases: A comprehensive review. J Clin Neurosci. 2020 Apr 27;: Authors: Das S, Zhang Z, Ang LC Abstract Clinical and neuropathological overlap of two or more neurodegenerative diseases (ND) is not an uncommon occurrence yet is still underdiagnosed in clinical neurological and neuropathological. The authors present a clinicopathological overview of the current understanding of overlapping...
J Clin Neurosci
Sat May 02, 2020 13:04
Rapid reversal of diffuse cerebral edema with correction of serum sodium in acute water intoxication.
Related ArticlesRapid reversal of diffuse cerebral edema with correction of serum sodium in acute water intoxication. J Clin Neurosci. 2020 Apr 27;: Authors: Austin A, Saha BK, Giampa J, Beegle SH Abstract Acute water intoxication (AWI) is a disorder of excess water intake that can manifest in neurological injury and death. We describe a case of a 54-year-old man that presents to the emergency department with a generalized toxic-clonic seizure due to...
J Clin Neurosci
Sat May 02, 2020 13:04
Accuracy and safety of cortical bone trajectory screw placement by an inexperienced surgeon using 3D patient-specific guides for transforaminal lumbar interbody fusion.
Related ArticlesAccuracy and safety of cortical bone trajectory screw placement by an inexperienced surgeon using 3D patient-specific guides for transforaminal lumbar interbody fusion. J Clin Neurosci. 2020 Apr 27;: Authors: Maruo K, Arizumi F, Kusuyama K, Kishima K, Tachibana T Abstract Cortical bone trajectory (CBT) is an alternative method for pedicle screw insertion. However, identification of the optimal entry point and the direction of the CBT...
J Clin Neurosci
Sat May 02, 2020 13:04
Open-loop and closed-loop control of posture: Stabilogram-diffusion analysis of center-of-pressure trajectories among people with stroke.
Related ArticlesOpen-loop and closed-loop control of posture: Stabilogram-diffusion analysis of center-of-pressure trajectories among people with stroke. J Clin Neurosci. 2020 Apr 27;: Authors: Treger I, Mizrachi N, Melzer I Abstract Many people with stroke (PwS) demonstrate reduced balance and increased postural sway afterwards, which may ultimately lead to falls and injury. In this study, we aimed to better understand postural sway behavior and the...
J Clin Neurosci
Sat May 02, 2020 13:04
Plasma copeptin levels in patients with multiple sclerosis.
Related ArticlesPlasma copeptin levels in patients with multiple sclerosis. J Clin Neurosci. 2020 Apr 25;: Authors: Koseoglu M, Ozben S, Gozubatik-Celik G, Tutuncu M, Kucuksayan E, Hanikoğlu A, Atakli D, Ozben T Abstract We compared copeptin levels in relapsing-remitting multiple sclerosis (RRMS) patients with controls and investigated how plasma copeptin levels were changed with the disease period. Thirty patients with RRMS without a prior attack in...
J Clin Neurosci
Thu Apr 30, 2020 13:36
Comparative Evaluation of Apnoea Graph and Polysomnography in Sleep Disordered Breathing in an Urban Indian Population
Abstract Apnoea graph (AG) system is a new technology designed for evaluation of Sleep Disordered Breathing and more importantly the site of obstruction in Obstructive Sleep Apnoea (OSA). Apnoea Graph being a new modality of assessment needs to be evaluated with the time tested gold standard PolySomnoGraphy (PSG) along with its unique capability of establishing the level of obstruction. A prospective study of 30 patients of snoring and/or suspected for OSA was conducted in Sir...
Otolaryngology Indian
Sat May 02, 2020 03:00
Head and Neck Lipomas at Uncommon Subsites: A Series of Four Cases
Abstract Lipomas are benign soft tissue tumors; the most common ones present in subcutaneous planes distributed throughout the body. However, there are few sites which are unusual location for lipomas. Here, we discuss the presentation of 4 cases of head and neck lipomas at unusual subsites. Though its prevalence is high in the body, lipomas are rarely seen in upper aerodigestive tract and these lesions can cause severe deglutition and respiratory distress problems in addition...
Otolaryngology Indian
Thu Apr 30, 2020 03:00
Safety Guidelines for Sterility of Face Shields During COVID 19 Pandemic
Abstract Face shields are personal protective equipment devices that are to be used by many health care workers during COVID 19 pandemic for protection of the facial area and associated mucous membranes (eyes, nose, mouth) from droplet spread of infection. Face shields are generally not used alone, but in conjunction with other protective equipment like cap, mask, goggle, and are therefore classified as adjunctive personal protective equipment. In the wake of scarcity of face...
Otolaryngology Indian
Thu Apr 30, 2020 03:00
An exploratory clinical study evaluating safety and performance of a volume-stable collagen matrix with coronally advanced flap for single gingival recession treatment
Abstract Objective To test the safety of a new volume-stable collagen matrix (VCMX) in combination with coronally advanced flap (CAF) for the treatment of single gingival recession. Material and methods Ten patients were treated for single RT1 gingival recession. Complete and mean root coverage, gingival thickness and keratinized tissue height, patient-reported...
Clinical Oral Investigations
Sat May 02, 2020 03:00
Autistic patients: a retrospective study on their dental needs and the behavioural approach
Abstract Introduction Autism spectrum disorder (ASD) is a lifelong heterogeneous psychiatric disorder that represents a challenge for dentists. The aim of this retrospective study was to analyse ASD patients’ dental needs and to investigate key factors influencing the behavioural management. Materials and methods One hundred eighteen ASD subjects...
Clinical Oral Investigations
Fri May 01, 2020 03:00
A new standardized critical size bone defect model in the pig forehead for comparative testing of bone regeneration materials
Abstract Objectives The preclinical study aimed to establish a standardized preclinical model to investigate osseous graft consolidation in defect configurations of limited regenerative capacity. Material and methods Critical size defects (CSD) were prepared and titanium tubes inserted for defect separation from local bone in the forehead area...
Clinical Oral Investigations
Fri May 01, 2020 03:00
Evaluation of polymerization shrinkage of bulk-fill resin composites using microcomputed tomography
Abstract Objectives This study evaluated the influence of cavity depth on polymerization shrinkage of bulk-fill resin composites with and without adhesive resin. Materials and methods Standardized box-shaped cavities (width, 4 mm; length, 5 mm, depth, 2 mm or 4 mm) were made on occlusal surfaces of extracted human third molars (N = 60). The...
Clinical Oral Investigations
Fri May 01, 2020 03:00
Apical root resorption after orthodontic treatment in patients with unilateral cleft lip and palate
Abstract Objectives The aims of this retrospective longitudinal study were to present the incidence of external apical root resorption (EARR) in the maxillary anterior teeth of patients with complete unilateral cleft lip and palate (CUCLP) and to evaluate the influence of orthodontic treatment variables on the development of EARR. Material and methods ...
Clinical Oral Investigations
Fri May 01, 2020 03:00
The modulation of the TREM-1/PGLYRP1/MMP-8 axis in peri-implant diseases
Abstract Objectives The aim of this study is to investigate the expression of sTREM-1 and its ligand PGLYRP1, as well as the expression of MMP-8 and its inhibitor TIMP-1, in peri-implant diseases. As a secondary aim, we analyzed the influence of the concomitant existence of periodontitis in the expression of these biomarkers. Materials and methods ...
Clinical Oral Investigations
Fri May 01, 2020 03:00
Periodontal treatment does not result in detectable platelet activation in vivo
Abstract Objectives Periodontitis is associated with systemic inflammation, elevated platelet activation and enhanced risk for cardiovascular diseases, while periodontal treatment reduces tissue inflammation and shows desirable effects on the oral biofilm and dental health. However, subgingival debridement during conservative treatment can lead to local trauma and transient bacteraemia, which might affect cardiovascular risk in these...
Clinical Oral Investigations
Fri May 01, 2020 03:00

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