Abstract Background The incidence of positional plagiocephaly has increased significantly over the last two decades, which has caused a service delivery challenge for pediatric neurosurgeons. As a potential solution to the long waitlists for abnormal head shape, a plagiocephaly clinic was established at BC Children’s Hospital (BCCH) in Vancouver, Canada. This clinic was supervised by an occupational therapist who had been trained by a...
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Annals of Clinical Microbiology and Antimicrobials - Effect of camera monitoring and feedback along with training on hospital infection rate in a neonatal intensive care unitIn terms of pediatric healthcare-associated infections (HAI), neonatal intensive care units (NICU) constitute the greatest risk. Contacting a health care personnel, either directly or indirectly, elevates NICU...Annals of Clinical Microbiology and Antimicrobials - Latest ArticlesWed Nov 13, 2019 02:00Mark above section as read Mediators...
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Publication date: Available online 12 November 2019Source: Clinical TherapeuticsAuthor(s): John C. Messina, Elliot Offman, Jennifer L. Carothers, Ramy A. MahmoudABSTRACTPurposeThe exhalation delivery system with fluticasone propionate (Xhance®) has been shown to deliver drug substantially more broadly in the nasal cavity (particularly into superior/posterior regions), with less off-target loss of drug to drip-out and swallowing, than conventional nasal sprays. This open-label study evaluated the...
Wed Nov 13, 2019 13:56
Publication date: Available online 11 November 2019Source: Clinical TherapeuticsAuthor(s): Moo-Yong Rhee, Kyung-Jin Kim, Sang-Hyun Kim, Young Won Yoon, Seung-Woon Rha, Soon Jun Hong, Choong-Hwan Kwak, Weon Kim, Chang-Wook Nam, Tae-Ho Park, Taek-Jong Hong, Sungha Park, Youngkeun Ahn, Namho Lee, Hui-Kyung Jeon, Dong Woon Jeon, Kyoo-Rok Han, Keon-Woong Moon, In-Ho Chae, Hae-Young KimAbstractPurposeThe goal of this study was to compare the lipid-lowering efficacy of the combination of ezetimibe and low-...
Tue Nov 12, 2019 17:51
Publication date: Available online 13 November 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Lauren J. Delaney, Cemile Basgul, Daniel W. MacDonald, Keith Fitzgerald, Noreen J. Hickok, Steven M. Kurtz, Flemming ForsbergAbstractPost-operative infection is a catastrophic complication of spinal fusion surgery, with rates as high as 10%, and existing preventative measures (i.e., peri-operative antibiotics) are only partially successful. To combat this clinical problem, we have designed a...
Wed Nov 13, 2019 13:55
Publication date: Available online 11 November 2019Source: Ultrasound in Medicine & BiologyAuthor(s): Hexuan Wang, Bradley Mills, Reem Mislati, Rifat Ahmed, Scott A. Gerber, David Linehan, Marvin M. DoyleyAbstractNeither contrast-enhanced computed tomography nor magnetic resonance imaging can monitor changes in the pancreatic ductal adenocarcinoma microenvironment during therapy. We hypothesized that shear wave elastography could overcome this limitation. To test this hypothesis, we measured...
Tue Nov 12, 2019 17:42
Publication date: Available online 12 November 2019Source: Journal of VoiceAuthor(s): Azlina Ab Rani, Mawaddah Azman, Muhammad Azhan Ubaidah, Mohd Razif Mohamad Yunus, Abdullah Sani, Marina Mat BakiSummaryObjectiveThis study compared the voice outcomes of selected patients with unilateral vocal fold palsy (UVFP) who underwent either nonselective laryngeal reinnervation (LR) or Type 1 thyroplasty (thyroplasty) in a Malaysian tertiary centre using multidimensional voice assessments.ParticipantsThe...
Wed Nov 13, 2019 13:47
Publication date: Available online 12 November 2019Source: Journal of VoiceAuthor(s): Eugenia San Segundo, Radek SkarnitzlSummaryIn this study we propose a new tool for the perceptual assessment of voice quality. For its design, we have adapted the Simplified Vocal Profile Analysis so that the new tool features two main characteristics: (1) the ordinal scalar degrees of the original protocol are turned into a visual analog scale; and (2) the original paper-based version of the protocol is now a computer-based...
Tue Nov 12, 2019 17:01
Publication date: Available online 12 November 2019Source: Archives of Oral BiologyAuthor(s): Alice Corrêa Silva-Sousa, Guido Artemio Marañón-Vásquez, Jennifer Tsi Gerber, Claudia Judachesci, Maria Bernadete Stuani, Mírian Aiko Nakane Matsumoto, Ricardo D. Coletta, Rafaela Scariot, Erika Calvano KuchlerAbstractObjectiveThe present study evaluated the association between genetic variants in WNT3A and WNT11, and palatal rugae phenotypes.DesignEighty-five biological unrelated orthodontic patients were...
Wed Nov 13, 2019 13:47
Publication date: Available online 11 November 2019Source: Archives of Oral BiologyAuthor(s): Masahiro Mizuhara, Kaori Kometani-Gunjigake, Kayoko Nakao-Kuroishi, Takashi Toyono, Suzuro Hitomi, Aoi Morii, Momotoshi Shiga, Yuji Seta, Kentaro Ono, Tatsuo KawamotoAbstractObjectivePain control is imperative in orthodontic treatment. Adenosine triphosphate (ATP) is a key mediator released from periodontal ligament cells that excites nociceptive nerve endings. Vesicular nucleotide transporter (VNUT), encoded...
Tue Nov 12, 2019 17:02
Publication date: Available online 13 November 2019Source: International ImmunopharmacologyAuthor(s): Marina U.W.B. Carvalho, Paola Vendramini, Christina Arslanian Kubo, Paulo Vítor Soreiro-Pereira, Rafael Sales de Albuquerque, Edson Antunes, Antonio Condino-NetoAbstractBAY 41-2272 increases guanosine 3′, 5′-cyclic monophosphate (cGMP) levels by stimulating soluble guanylate cyclase (sGC). In this study, we evaluated the effect of BAY 41-2272 on human T lymphocyte functions. Pretreating T cells for...
Wed Nov 13, 2019 13:46
Publication date: Available online 13 November 2019Source: International ImmunopharmacologyAuthor(s): Sijia Peng, Jingjing Jia, Jingjing Sun, Qizhi Xie, Xiaoyun Zhang, Yuanfei Deng, Li YiAbstractMicroglia activation is closely linked to ischemia, various chronic neurodegenerative diseases (e.g., Alzheimer′s disease, Parkinson′s disease, multiple sclerosis, amyotrophic lateral sclerosis), and many other central nervous system diseases. Accumulating evidence suggests that depressing the microglial...
Wed Nov 13, 2019 13:46
Publication date: Available online 11 November 2019Source: International ImmunopharmacologyAuthor(s): Hui Zhang, Xinyang Gong, Shimao Ni, Yu Wang, Lingbo Zhu, Ningning JiAbstractBackgroundsC1q tumor necrosis factor-related protein 9 (CTRP9) has been suggested to exert an atheroprotective effect by modulating the inflammation, foam cell formation, endothelia and smooth muscle cell function via Adenosine Monophosphate Activated Protein Kinase (AMPK) pathway. On the other hand, the NLR Family Pyrin...
Tue Nov 12, 2019 17:09
Publication date: Available online 11 November 2019Source: International ImmunopharmacologyAuthor(s): Sara Ghaffarpour, Abbas Foroutan, Nayere Askari, Fatemeh Mashhadi Abbas, Eisa Salehi, Maryam Nikoonejad, Mohammad Mehdi Naghizadeh, Maryam Eskandarian, Keivan Gohari Moghadam, Hassan Mohammad Hosseini Akbari, Mohammad Ebrahim Yarmohammadi, Tooba GhazanfariAbstractIntroductionLong-term pulmonary complications are one of the major long-term consequences of sulfur mustard (SM) exposure. Toll-like receptor...
Tue Nov 12, 2019 17:09
Publication date: Available online 13 November 2019Source: The Journal of Prosthetic DentistryAuthor(s): Adolfo Di Fiore, Gianpaolo Savio, Edoardo Stellini, Paolo Vigolo, Carlo Monaco, Roberto MeneghelloAbstractStatement of problemThe marginal gap and ceramic bond strength of metal-ceramic restorations are important for success. However, studies evaluating the marginal gap and ceramic bond strength of fixed partial dentures (FPDs) produced with 3D printing technologies such as selective laser melting...
Wed Nov 13, 2019 13:44
Publication date: Available online 13 November 2019Source: The Journal of Prosthetic DentistryAuthor(s): Jung-Jin Lee, Dong-Hwan Kim, Kwantae NohAbstractFor the retention and stability of removable complete dentures, the denture base should be fabricated with appropriate borders and polished surfaces. A technique for transferring the contour of a functional impression for digitally fabricated removable complete dentures is described.
Wed Nov 13, 2019 13:44
Publication date: Available online 13 November 2019Source: The Journal of Prosthetic DentistryAuthor(s): Saumya Kapoor, Saumyendra V. Singh, Deeksha Arya, Pooran ChandAbstractOne of the difficulties faced during the essential and demanding step of fabricating a mold for a partial auricular prosthesis is the fracture of its most elevated part, which engages the remnant concha and triangular fossa region, because of the presence of excessive convolutions and undercuts. This technique describes a 4-part...
Wed Nov 13, 2019 13:44
Publication date: Available online 13 November 2019Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Mohammad Mehdi Movahedi, Zahra Alamzadeh, Samira Hosseini-Nami, Ali Shakeri-Zadeh, Gholamreza Taheripak, Amirhossein Ahmadi, Arash Zare-Sadeghi, Habib Ghaznavi, Alireza MehdizadehAbstractWe have recently reported the synthesis and characterization of gold-coated iron oxide nanoparticle and demonstrated such a nanoparticle (Au@Fe2O3 NP) was able to significantly enhance the lethal effects of...
Wed Nov 13, 2019 13:41
Publication date: Available online 12 November 2019Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Michelle Barreto Requena, Pedro Ernesto Russignoli, José Dirceu Vollet-Filho, Ana Gabriela Salvio, Thereza Cury Fortunato, Sebastião Pratavieira, Vanderlei Salvador BagnatoAbstractBackgroundPhotodynamic Therapy (PDT) is an alternative treatment for non-melanoma skin cancer. One of the main challenges of topical PDT is to increase the precursor penetration when applied on the lesion. Protoporphyrin...
Wed Nov 13, 2019 13:41
Publication date: Available online 12 November 2019Source: Photodiagnosis and Photodynamic TherapyAuthor(s): José Athayde Vasconcelos Morais, Mosar C. Rodrigues, Fernanda F. Ferreira, Kunal Ranjan, Ricardo Bentes Azevedo, Marcio J. Poças-Fonseca, Luis A. MuehlmannAbstractCryptococcosis is a disseminated infection caused mainly by C. neoformans and C. gattii. Limitations for the treatment involve the selection of isolates resistant to conventional antifungal drugs, prolonged treatment time and drugs...
Tue Nov 12, 2019 17:20
Publication date: Available online 12 November 2019Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Mohamad S. AlSalhi, Sandhanasamy Devanesan, Muhammad Atif, M. Naveed Akhtar Saleem, Tahir N. Khan, Fatima AlQahtani, Vadivel MasilamaniAbstractHemophilia (HP), the deficiency of clotting factors such as VIII (FVIII) and IX, is an inherited blood disorder which is due to the lack of clotting protein. Conventional techniques for detecting hemophilia are based on clotting factor tests such as...
Tue Nov 12, 2019 17:20
Publication date: Available online 12 November 2019Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Waseem Jerjes, Zaid Hamdoon, Colin Hopper
Tue Nov 12, 2019 17:20
Publication date: Available online 12 November 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Meena Rafiq, Andrew Hayward, Charlotte Warren-Gash, Spiros Denaxas, Arturo Gonzalez-Izquierdo, Georgios Lyratzopoulos, Sara ThomasAbstractBackgroundImmunodeficiency syndromes (acquired/congenital/iatrogenic) are known to increase Hodgkin’s lymphoma (HL) risk, but the effect of allergic immune dysregulation and corticosteroids are poorly understood.ObjectiveTo assess the risk of HL associated...
Wed Nov 13, 2019 13:26
Publication date: Available online 12 November 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Elaine Fuertes, Joachim Heinrich
Wed Nov 13, 2019 13:26
The genus Astrophiura, which ranks among the most extraordinary of modern brittle stars, is the type genus of the recently resurrected family Astrophiuridae within the order Ophiurida. On account of its absurdly enlarged and strongly modified lateral arm plates, Astrophiura bears a closer resemblance to a pentagonal starfish than to a typical ophiuroid. Although molecular evidence suggests an ancient origin of the Astrophiuridae, dating back at least to the Early Jurassic, not a single fossil astrophiurid...
Wed Nov 13, 2019 02:00
Microsatellites are widely used as powerful markers in population genetics because of their ability to access recent genetic variation and to resolve subtle population genetic structures. However, their development, especially for non-model organisms with no available genome-wide sequence data has been difficult and time-consuming. Here, a commercial high-throughput sequencing approach (HTS) was used for the very first identification of microsatellite motifs in the genome of Xyela concava and the...
Wed Nov 13, 2019 02:00
Smaller animals display pecular characteristics related to their small body size, and miniaturization has recently been intensely studied in insects, but not in other arthropods. Collembola, or springtails, are abundant soil microarthropods and form one of the four basal groups of hexapods. Many of them are notably smaller than 1 mm long, which makes them a good model for studying miniaturization effects in arthropods. In this study we analyze for the first time the anatomy of the minute springtail...
Wed Nov 13, 2019 02:00
The genus Trogloderus LeConte, 1879, which is restricted to dunes and sandy habitats in the western United States, is revised using morphological and molecular information. Six new species are described from desert regions: Trogloderus arcanus New Species (Lahontan Trough); Trogloderus kandai New Species (Owens Valley); Trogloderus major New Species (Mohave Desert); Trogloderus skillmani New Species (eastern Great Basin and Mohave Desert); Trogloderus verpus New Species (eastern Colorado Plateau);...
Wed Nov 13, 2019 02:00
Background Acute kidney injury (AKI) is a major problem for health systems being directly related to short and long-term morbidity and mortality. In the last years, the incidence of AKI has been increasing. AKI and chronic kidney disease (CKD) are closely interconnected, with a growing rate of CKD linked to repeated and severe episodes of AKI. AKI and CKD can occur also secondary to imbalanced oxidative stress (OS) reactions, inflammation, and apoptosis. The kidney is particularly sensitive to...
Wed Nov 13, 2019 02:00
Although more massive flight muscles along with larger wings, higher wingbeat frequencies and greater stroke amplitudes enhance force and power production in flapping flight, the extent to which these parameters may be correlated with other morphological features relevant to flight physiology and biomechanics remains unclear. Intraspecifically, we hypothesized that greater vertical load-lifting capacity would correlate with higher wingbeat frequencies and relatively more massive flight muscles, along...
Wed Nov 13, 2019 02:00
Background Ulcerative colitis is a type of inflammatory bowel disease posing a great threat to the public health worldwide. Previously, gene expression studies of mucosal colonic biopsies have provided some insight into the pathophysiological mechanisms in ulcerative colitis; however, the exact pathogenesis is unclear. The purpose of this study is to identify the most related genes and pathways of UC by bioinformatics, so as to reveal the core of the pathogenesis. ...
Wed Nov 13, 2019 02:00
The development of breast cancer (BC) subtypes is controlled by distinct sets of candidate genes, and the expression of these genes is regulated by the binding of their mRNAs with miRNAs. Predicting miRNA associations and target genes is thus essential when studying breast cancer. The MirTarget program identifies the initiation of miRNA binding to mRNA, the localization of miRNA binding sites in mRNA regions, and the free energy from the binding of all miRNA nucleotides with mRNA. Candidate gene...
Wed Nov 13, 2019 02:00
Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor that regulates lipid/glucose homeostasis and adipocyte differentiation. While the role of PPARγ in adipogenesis and diabetes has been extensively studied, little is known about PPARγ function during early embryonic development. Within zebrafish, maternally-loaded pparγ transcripts are present within the first 6 h post-fertilization (hpf), and de novo transcription of zygotic pparγ commences at ~48 hpf....
Wed Nov 13, 2019 02:00
Background Soil aggregate-size classes and microbial communities within the aggregates are important factors regulating the soil organic carbon (SOC) turnover. However, the response of soil bacterial and fungal communities in aggregates to litter decomposition in different aggregate-size classes is poorly understand. Methods Soil samples from un-grazed natural grassland were separated into four dry aggregate classes...
Wed Nov 13, 2019 02:00
Background Milk is a complicated chemical mixture often studied through macronutrient concentrations of fat, protein, and sugar. There is a long-standing natural history tradition describing interspecific diversity in these concentrations. However, recent work has shown little influence of ecological or life history variables on them, aside from maternal diet effects, along with a strong phylogenetic signal. Methods ...
Wed Nov 13, 2019 02:00
Spatial and temporal patterns in stream temperature are primary factors determining species composition, diversity and productivity in stream ecosystems. The availability of spatially and temporally continuous estimates of stream temperature would improve the ability of biologists to fully explore the effects of stream temperature on biota. Most statistical stream temperature modeling techniques are limited in their ability to account for the influence of variables changing across spatial and temporal...
Tue Nov 12, 2019 02:00
Lake trophic state classifications provide information about the condition of lentic ecosystems and are indicative of both ecosystem services (e.g., clean water, recreational opportunities, and aesthetics) and disservices (e.g., cyanobacteria blooms). The current classification schemes have been criticized for developing indices that are single-variable based (vs. a complex aggregate of multi-variables), discrete (vs. a continuous), and/or deterministic (vs. an inherently random). We present an updated...
Tue Nov 12, 2019 02:00
Background Aminopeptidases play important roles in various biological processes in nematodes including growth, development and reproduction. Although the aminopeptidases have been shown to regulate reproduction in Caenorhabditis elegans (C. elegans), the role of aminopeptidases in development and aging has not been reported. This study focused on the function of aminopeptidase AlaNyl aminopeptidase 1 (ANP-1) on development in C. elegans. Methods In the present study, we reported the identification...
Tue Nov 12, 2019 02:00
Hosting unique and important plant germplasms, the Qinghai-Tibet Plateau (QTP), as the third pole of the world, and Xinjiang, located in the centre of the Eurasian continent, are major distribution areas of perennial Triticeae grasses, especially the widespread Elymus species. Elymus excelsus Turcz. ex Griseb, a perennial forage grass with strong tolerance to environmental stresses, such as drought, cold and soil impoverishment, can be appropriately used for grassland establishment due to its high...
Tue Nov 12, 2019 02:00
Background Kinetic motion analysis has been used in canines and equines as a fundamental objective evaluation measurement. Cats are very capable jumpers, and this ability has biomimetic applications. It is essential to understand movement patterns and physical adaptations of this species, as cats are popular pets for humans. Further to this, motion analysis of a cat’s movement patterns may provide potentially valuable information in relation to limb disease and injury. Therefore, the aim of this...
Tue Nov 12, 2019 02:00
Background In horses and ponies numerous medical conditions are known to be linked with inflammation in different tissues, especially in the liver. Besides affecting other metabolic pathways such as the expression of certain interleukins (IL), inflammation is associated with stress of the endoplasmic reticulum (ER). In particular, ER stress leads to adaptive stress response and can be measured by several markers of inflammatory and stress signalling pathways, like nuclear factor...
Tue Nov 12, 2019 02:00
Objectives: The objective of the present study was to explore the voice concerns and vocal and nonvocal habits of Vedic chanters. Participants and Method: A cross-sectional design was used to study 200 Vedic chanters using a 36-item questionnaire. This questionnaire was developed and administered to explore their voice concerns and vocal and nonvocal habits. Descriptive statistics were used to summarize the findings and K-means cluster analysis was carried out to identify clusters concerning voice...
Wed Nov 13, 2019 09:25
Publication date: Available online 13 November 2019Source: Academic RadiologyAuthor(s): Constance de Margerie-Mellon, Ritu R. Gill, Antonio C. Monteiro Filho, Benedikt H. Heidinger, Allison Onken, Paul A. VanderLaan, Alexander A. BankierRationale and ObjectivesTo analyze the performances of diameter-based measurements, either using diameters, or by calculating diameter-based volumes, as compared to volume measurements in assessing growth of pulmonary adenocarcinomas manifesting as subsolid nodules...
Wed Nov 13, 2019 12:22
Publication date: Available online 11 November 2019Source: Academic RadiologyAuthor(s): Jing Ye, Qing Xu, Shou-An Wang, Jin Zheng, Wei-Qiang DouRationale and ObjectivesTo evaluate the diagnostic value of intravoxel incoherent motion and diffusion kurtosis imaging parameters for clear cell renal cell carcinoma (ccRCC) grading.Materials and MethodsA total of 60 patients with pathologically proven ccRCC who underwent intravoxel incoherent motion and diffusion kurtosis imaging were retrospectively evaluated....
Tue Nov 12, 2019 12:49
Publication date: Available online 11 November 2019Source: Academic RadiologyAuthor(s): Giovanni D. Rodriguez, Richard B. Gunderman
Tue Nov 12, 2019 12:49
Publication date: Available online 11 November 2019Source: Academic RadiologyAuthor(s): Absia Jabbar, Shahzaib Nabi, Adeel Arshad, Muhammad Ali
Tue Nov 12, 2019 12:49
Publication date: Available online 11 November 2019Source: Academic RadiologyAuthor(s): Lukas Lenga, Marvin Lange, Christophe T. Arendt, Christian Booz, Ibrahim Yel, Boris Bodelle, Tommaso D'Angelo, Renate M. Hammerstingl, Nicole A. Huizinga, Thomas J. Vogl, Simon S. Martin, Moritz H. AlbrechtRationale and ObjectivesTo compare dual-energy CT virtual monoenergetic images (VMI) and standard reconstructions for reliability of quantitative size measurements and diagnostic accuracy for the detection of...
Tue Nov 12, 2019 12:49
Abstract Hymenoptera venom immunotherapy (VIT) extracts can be non‐purified aqueous, purified aqueous, or purified aluminium hydroxide adsorbed (“depot”) preparations. All of these are efficacious, but the choice of preparation will influence the updosing protocol and dose interval. Pharmalgen Bee Venom and Wasp Venom (ALK) are partially‐purified aqueous products, and until now have been the only licensed products available in the UK.
Tue Nov 12, 2019 22:59
Abstract Background and aims The on purpose‐modulated dendritic cells (DCs) have shown charming effects on restoring immune regulatory functions in subjects with immune diseases. This study aims to construct DCs carrying chimerical antigen (Ag) peptides (CAP‐DCs) to induce interleukin (IL)‐17+ inducible Tregs (iTregs) to alleviate food allergy (FA) in a murine model. Methods In this study, we constructed CAP‐DCs. The CAP is a fusion protein, consisting of a segment of recombinant scFv of...
Tue Nov 12, 2019 12:04
Objectives The purpose of this manuscript is to review the successive regulatory actions and decisions following the initial publication by Kanda and colleagues in 2014 regarding gadolinium retention in the human brain after multiple gadolinium-based contrast agents (GBCAs) administrations. Materials and Methods Starting from 2014, the actions and decisions made by all regulatory authorities were collected and summarized region by region. Volumes of GBCA sales in 2018 per region and main...
Wed Oct 16, 2019 03:00
Objectives This study aimed to develop a dual-input convolutional neural network (CNN)–based deep-learning algorithm that utilizes both anteroposterior (AP) and lateral elbow radiographs for the automated detection of pediatric supracondylar fracture in conventional radiography, and assess its feasibility and diagnostic performance. Materials and Methods To develop the deep-learning model, 1266 pairs of AP and lateral elbow radiographs examined between January 2013 and December 2017 at a...
Wed Oct 16, 2019 03:00
Objective The aim of this study was to compare bone imaging between ultrashort echo-time (UTE) magnetic resonance (MR) imaging and cone-beam computed tomography (CBCT) as the reference standard in patients with medication-related osteonecrosis of the jaw (MRONJ). Materials and Methods A 1-year retrospective, blinded, and randomized qualitative analysis of UTE MR images and CBCT from 19 patients with clinically diagnosed MRONJ was performed by 2 independent radiologists. Medication-related...
Wed Oct 16, 2019 03:00
Abstract Objectives Climate change is having a significant impact on biodiversity and increasing attention is therefore being devoted to identifying the behavioral strategies that a species uses to cope with climatic stress. We explore how wild vervet monkeys (Chlorocebus pygerythrus) respond to heat stress, and how behavioral adaptations are used to regulate body temperature. Materials and methods We implanted wild vervet monkeys with temperature‐sensitive data loggers and related the...
Tue Nov 12, 2019 15:00
Abstract Objectives Finite element analysis has gained popularity in anthropological research to connect morphological form to measurable function but requires that loads are applied at appropriate anatomical locations. This is challenging for the ankle because the joint surfaces are not easily determined given their deep anatomical location. While the location of the talonavicular and subtalar joints can be directly determined via medical imaging, regression equations are a common, less invasive...
Tue Nov 12, 2019 14:55
Background Photoacoustic tomography (PAT) is a noninvasive vascular imaging modality that uses near‐infrared pulse laser beams and ultrasound (US) to visualize vessels. We previously demonstrated the utility of PAT for visualizing anterolateral thigh (ALT) perforators in a clinical study of 10 thighs in 5 healthy adults. Evaluation of the correlation between PAT and US findings showed that PAT had comparable diagnostic potential but was superior in visualizing subcutaneous microvessels; however,...
Tue Nov 12, 2019 15:17
Abstract Periodontitis is an inflammation characterized by alveolar bone resorption caused by imbalance in bone homeostasis. It is known that autophagy is related to inflammation and bone metabolism. However, whether autophagy inhibitors could be used for periodontitis in animal models remains unknown. We investigated the role of two classical autophagy inhibitors, 3-methyladenine (3-MA) and chloroquine (CQ), on the development of rat experimental periodontitis in terms of the...
Wed Nov 13, 2019 02:00
Abstract This study investigated the effects of systemic treatment with a new formulation of resveratrol (RSV) vehicled in rice oil (RSVO) in experimental rat models of inflammation. Male Wistar rats were evaluated in the following in vivo models: carrageenan-induced acute edema, complete Freund’s adjuvant (CFA)-evoked sub-chronic edema, and CFA-induced polyarthritis. The animals were treated orally with RSVO (10–15 mg/kg) or RSV (100–200 mg/kg), depending on the experimental protocol....
Wed Nov 13, 2019 02:00
Abstract Damaged vascular endothelial cells after ischemic stroke release inflammatory cytokines and adhesion molecules, which could trigger platelet adhesion to vascular endothelial cells and platelet activation, and accelerate thrombus formation. Tetramethylpyrazine is the main bioactive component of Chuanxiong, which has demonstrated considerable protective effects in cerebrovascular diseases. However, the effect and mechanisms of tetramethylpyrazine...
Wed Nov 13, 2019 02:00
Abstract Curcumin, extracted from the roots of Curcuma longa, has been used as an anti-inflammatory agent since the time of Ayurveda. The present work was designed to evaluate the potential of curcumin in amelioration of ovalbumin (OVA) induced AD in mice. Female BALB/c mice were subjected to skin OVA-patch application for a period of 1 week followed by resting period of 2 weeks, and the same protocol was repeated thrice. Curcumin was administered...
Wed Nov 13, 2019 02:00
Abstract -20pt?>Mycobacterium tuberculosis (Mtb) is a pathogenic bacterium that causes contagious tuberculosis (TB). Recently, Mtb-secreted proteins have been considered virulence factors and candidates for drugs and vaccines. Among these proteins, 6-kDa early secreted antigenic target (ESAT-6) is known to be able to induce component of matrix metalloproteinase-9 (MMP-9) in epithelial cells, leading to recruitment of macrophages. However,...
Wed Nov 13, 2019 02:00
Abstract Background Differentiating parathyroid from thyroid lesions can be difficult on fine‐needle aspiration (FNA) due to overlapping cytomorphologic features. While the traditional parathyroid hormone (PTH) assays can help in the distinction, these tests may be cumbersome, particularly when the lesion is unexpected clinically and a needle wash is not collected at the time of FNA. Therefore, we chose to investigate the application of immunohistochemical staining (IHC) with GATA 3 and thyroid...
Tue Nov 12, 2019 14:49
Abstract Vaping‐induced lung injury is a recently recognized phenomenon owing to the rising popularity of e‐cigarette use. A cluster of cases of varying severity, including six deaths, was recently reported in the United States by the Centers for Disease Control. The objective of this report is to highlight the cytologic features suggestive of vaping‐induced lung injury. A 20‐year‐old previously healthy man presented with a 7‐day history of progressively worsening respiratory symptoms including...
Tue Nov 12, 2019 14:45
Abstract Cryptococcal meningitis commonly affects immunocompromised cases and can have varied presentation. In some instances, the presence of a plethora of inflammatory cells on cerebrospinal fluid (CSF) in an immunosuppressed patient can lead to further investigations, which unravel the presence of cryptococcal meningitis. The aim of this retrospective study was to analyze the spectrum of CSF findings of immunosuppressed patients who were diagnosed to have cryptococcal meningitis. Retrospective...
Tue Nov 12, 2019 14:40
Tue Nov 12, 2019 14:29
We examined factors related to the uptake of two malaria prevention measures, insecticide-treated bed-nets and prophylactic sulphadoxine-pyrimethamine (SP), among pregnant women in Nnewi, Nigeria. The survey had a quantitative and qualitative part. For each part, the subjects meeting our inclusion criteria were systematically identified in a population-based manner. For the qualitative part, focused group discussions, in-depth interviews with a wide variety of stakeholders (e.g., health workers,...
Wed Nov 13, 2019 06:05
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01759C, PaperSayyed Hashem Sajjadi, Hossein Ahmadzadeh, Elaheh K GoharshadNanoparticles (NPs) are able to improve the separation efficiency of proteins in SDS-polyacrylamide gel electrophoresis (SDS-PAGE) due to their capability in enhancing heat dissipation during electrophoresis. However, the intrinsic surface...The content of this RSS Feed (c) The Royal Society of Chemistry
Wed Nov 13, 2019 02:00
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01848D, PaperNuo Zhang, Yaoguang Wang, Guanhui Zhao, Chao Wang, Yueyuan Li, Yong Zhang, Huan Wang, Qin WeiAn ultrasensitive label-free photoelectrochemical (PEC) immunosensor was developed to detect amyloid β-protein (Aβ) based on CdS/CdTe cosensitized SnO2 nanoflowers. Specifically, SnO2 with flower-like porous nanostructure was utilized as a perfect...The content of this RSS Feed (c) The Royal Society of Chemistry
Wed Nov 13, 2019 02:00
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01679A, PaperKyu Shik Eom, Yijae Lee, Hye Won Seo, Ji Yoon Kang, Joon S. Shim, Soo Hyun LeeAn excessive cholesterol level can lead to cardiovascular diseases, such as stroke, hypertension, and myocardial infarction. A non-invasive, painless method of determining the cholesterol in the blood would improve the...The content of this RSS Feed (c) The Royal Society of Chemistry
Wed Nov 13, 2019 02:00
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01758E, PaperCorentin Jacquemmoz, François Giraud, Jean-Nicolas DumezNuclear magnetic resonance (NMR) spectroscopy is a powerful tool for reaction monitoring. Several devices have been recently developed for online monitoring, using flow NMR, of batch reactions carried out in...The content of this RSS Feed (c) The Royal Society of Chemistry
Tue Nov 12, 2019 02:00
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN02007A, PaperMingying Zhao, Fagong Xu, Lun Wang, Hongqi Chenerrous ion (Fe2+) is an important component of hemoglobin and plays a role in transporting O2 to human tissues. If iron deficiency is found, iron deficiency anemia may occur, so...The content of this RSS Feed (c) The Royal Society of Chemistry
Tue Nov 12, 2019 02:00
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01628G, PaperMahsa Taleghan Ghafari, Fahimeh Varmaghani, Babak Karimi, Vahid KhakyzadehTwo-electron oxidation of N,N,N',N'-tetramethyl-p-phenylenediamine (TMPD) results in highly unstable TMPD2+ in aqueous solutions. Despite its low redox potential, TMPD2+/TMPD couple is not considered as a suitable charge transfer functional group...The content of this RSS Feed (c) The Royal Society of Chemistry
Tue Nov 12, 2019 02:00
Abstract Background The purpose of this study was to investigate if FDG uptake metrics in primary tumor and lymph node metastases in patients with oropharyngeal squamous cell carcinoma (OPSCC) has a prognostic value beyond UICC8 staging in a multiple endpoint model. Methods Patients with OPSCC treated with primary radiotherapy at Rigshospitalet in the period...
Wed Nov 13, 2019 02:00
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Tue Nov 12, 2019 02:00
Tue Nov 12, 2019 02:00
Abstract Background Craniofacial morphogenesis is the result of an intricate multistep network of tightly controlled spatial and temporal signalling that involves several molecules and transcription factors organised into highly coordinated pathways. Any alteration in even one step of this delicate process can lead to congenital malformations such as cleft palate. One of the first steps in embryonal orofacial development is the migration of cells from the neural crests to the branchial arches....
Tue Nov 12, 2019 14:28
Sprache Stimme GehörDOI: 10.1055/a-0949-7081© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Full text
Tue Nov 12, 2019 01:00
Sprache Stimme GehörDOI: 10.1055/a-0949-6520The aim of the present study was a systematic literature review on selected evidence-based voice therapy programs for the treatment of various types of dysphonia. The results showed that nine of seventeen voice therapy programs complied the selection criteria. All nine voice therapy programs revealed significant improvements in various aspects of laryngeal evaluation, voice quality, vocal function, and/or self-evaluation. These improvements might be expected...
Tue Nov 12, 2019 01:00
This study compared the voice outcomes of selected patients with unilateral vocal fold palsy (UVFP) who underwent either nonselective laryngeal reinnervation (LR) or Type 1 thyroplasty (thyroplasty) in a Malaysian tertiary centre using multidimensional voice assessments.
Tue Nov 12, 2019 02:00
Abstract Objective to conduct a systematic review and meta‐analysis to evaluate the recent scientific literature addressing the association between periodontitis and asthma, chronic obstructive pulmonary disease (COPD), and pneumonia. Materials and Methods the search for studies was carried out using MedLine/PubMed, Embase, Lilacs, Web of Science, Scopus, and SciELO databases, including the gray literature (ProQuest). Reference lists of selected articles were also searched. Studies having...
Tue Nov 12, 2019 22:43
Abstract Objectives Using next‐generation sequencing (NGS) to determine whether aggressive periodontitis is associated with specific mitochondrial polymorphisms. Materials and Methods A total of 165 unrelated Han Chinese were enrolled in the study. We analyzed the mitochondrial DNA (mtDNA) in 97 patients with aggressive periodontitis and 68 healthy controls by NGS. The mitochondrial DNA was L‐PCR‐amplified and subsequently sequenced by an Illumina Genome Analyzer (NGS). Chi‐square tests...
Tue Nov 12, 2019 22:29
Abstract Objective To assess the association between polymorphic variants from SHMT1 and MTHFS genes, involved in the cytoplasmic futile folate cycle, and the risk of nonsyndromic cleft lip with or without cleft palate (NSCL/P) in the Chilean population. Subjects and Methods In a sample of 139 Chilean NSCL/P cases and 278 controls, we obtained the genotypes for 9 variants of SHMT1 and MTHFS and the association between them and the phenotype was evaluated using odds ratios (OR) in additive...
Mon Nov 11, 2019 20:24
Journal Name: Journal of Pediatric Endocrinology and MetabolismIssue: Ahead of print
Wed Nov 13, 2019 00:02
Journal Name: Journal of Pediatric Endocrinology and MetabolismIssue: Ahead of print
Wed Nov 13, 2019 00:02
Journal Name: Journal of Pediatric Endocrinology and MetabolismIssue: Ahead of print
Wed Nov 13, 2019 00:02
Abstract Purpose To establish the efficacy of oral antidepressants compared to placebo in improving obstructive sleep apnea (OSA) as measured on a polysomnography study. Secondary outcomes included self-reported sleepiness. Methods Authors identified prospective randomized placebo-controlled studies from MEDLINE through PubMed, Web of Science, the Cochrane...
Tue Nov 12, 2019 02:00
Abstract Objective To evaluate the performance of clinical criteria (CC) for diagnosis and initiation of empirical treatment with continuous positive airway pressure (CPAP) in patients with suspected obstructive sleep apnea (OSA) compared with the treatment decision based on sleep studies (polysomnography or respiratory polygraphy), guidelines, and experience of participating physicians. ...
Tue Nov 12, 2019 02:00
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